| Compound ID |
Compound Name |
Compound Formula |
|
CP0568367
|
(E)-N-[7-hydroxy-4-(4-imidazo[1,2-c]pyrimidin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C29H28N8O3
|
1
|
| 1 |
IC50 = 1.06 nM
|
|
|
|
CP0543323
|
(E)-3-[(2R)-1-methylpyrrolidin-2-yl]-N-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C28H27N9O2
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0543324
|
(E)-N-[7-hydroxy-4-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C29H28N8O3
|
1
|
| 1 |
IC50 = 1.43 nM
|
|
|
|
CP0570125
|
(E)-N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H31N9O3
|
1
|
| 1 |
IC50 = 1.67 nM
|
|
|
|
CP0568342
|
(E)-N-[7-hydroxy-4-(4-imidazo[1,2-a]pyridin-7-yloxy-3-methylanilino)quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H29N7O3
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0537778
|
N-[5-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
|
C29H25ClN6O4
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0569329
|
N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enamide
Show/Hide
|
C25H22N8O3
|
1
|
| 1 |
IC50 = 1.93 nM
|
|
|
|
CP0374475
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C19H18ClFN6O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0545159
|
(E)-N-[7-hydroxy-4-(3-methyl-4-pyrazolo[1,5-a]pyrimidin-6-yloxyanilino)quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C29H28N8O3
|
1
|
| 1 |
IC50 = 2.41 nM
|
|
|
|
CP0570253
|
2-methoxy-N-[(E)-3-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]prop-2-enyl]acetamide
Show/Hide
|
C26H24N8O3
|
1
|
| 1 |
IC50 = 2.55 nM
|
|
|
|
CP0007142
|
N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]quinazolin-4-amine
Show/Hide
|
C29H26ClFN4O4S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0579281
|
(E)-4-(dimethylamino)-N-[4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]but-2-enamide
Show/Hide
|
C26H25N9O2
|
1
|
| 1 |
IC50 = 2.85 nM
|
|
|
|
CP0570251
|
(Z)-N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-2-fluoro-3-[(2S)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H30FN9O3
|
1
|
| 1 |
IC50 = 3.38 nM
|
|
|
|
CP0570553
|
N-[3-[4-[(2-benzyl-3H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C29H23N7O
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0569797
|
(Z)-N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-2-fluoro-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H30FN9O3
|
1
|
| 1 |
IC50 = 3.51 nM
|
|
|
|
CP0568371
|
(E)-N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-2-fluoro-3-[(2S)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H30FN9O3
|
1
|
| 1 |
IC50 = 3.68 nM
|
|
|
|
CP0578292
|
N-[3-[4-(4-hydroxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C32H31N7O2
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0431426
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C31H33N7O3
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0543325
|
N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-2-fluoroprop-2-enamide
Show/Hide
|
C25H21FN8O3
|
1
|
| 1 |
IC50 = 4.05 nM
|
|
|
|
CP0498546
|
N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H22N6O4
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0551544
|
N-[3-[4-(4-benzhydryloxyanilino)-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C45H41N7O2
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0033646
|
AZD-9291
Show/Hide
|
C28H33N7O2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0379991
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C33H35N7O3
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0078880
|
4-Dimethylamino-but-2-enoic acid {4-[3-chloro-4-(pyridin-2-ylmethoxy)-phenylamino]-3-cyano-7-ethoxy-quinolin-6-yl}-amide
Show/Hide
|
C30H29ClN6O3
|
2
|
| 1 |
IC50 = 5.57 nM
|
|
|
| 2 |
IC50 = 9.7 nM
|
|
|
|
CP0568340
|
(E)-N-[7-hydroxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-a]pyridin-7-yloxy)anilino]quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C29H28N8O3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0571295
|
(E)-N-[7-hydroxy-4-(4-imidazo[1,2-a]pyridin-6-yloxy-3-methylanilino)quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H29N7O3
|
1
|
| 1 |
IC50 = 6.42 nM
|
|
|
|
CP0514244
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[(6-morpholin-4-ylpyrido[3,4-d]pyrimidin-4-yl)amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C30H31F2N7O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0545155
|
(E)-N-[7-ethoxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinazolin-6-yl]-2-fluoro-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H30FN9O3
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0053637
|
(S)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamide
Show/Hide
|
C24H25ClFN5O3
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
|
CP0515185
|
N-[3-[4-[(1-benzylindol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H24N6O
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0283069
|
US8901140, 5
Show/Hide
|
C32H31ClN6O3
|
1
|
| 1 |
IC50 = 9.07 nM
|
|
|
|
CP0098558
|
N-[2-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]pyrrolo[3,2-d]pyrimidin-5-yl]ethyl]-3-hydroxy-3-methylbutanamide
Show/Hide
|
C26H25ClF3N5O3
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0564224
|
N-[5-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(3-hydroxypropoxy)phenyl]prop-2-enamide
Show/Hide
|
C30H27ClN6O4
|
1
|
| 1 |
IC50 = 9.3 nM
|
|
|
|
CP0467074
|
(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C31H31ClFN5O3
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0568368
|
(E)-N-[3-cyano-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C30H27N9O2
|
1
|
| 1 |
IC50 = 10.77 nM
|
|
|
|
CP0431430
|
(E)-4-(dimethylamino)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
|
C25H25N7O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0642885
|
N-(4-(3-chloro-4-fluorophenylamino)-7-(3-morpholinopropoxy)quinazolin-6-yl)acrylamide dihydrochloride
Show/Hide
|
C24H27Cl3FN5O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0491530
|
N-[3-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C27H21ClN6O2
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0513510
|
N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H22N6O3
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0379990
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C30H31N7O2
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0126507
|
HM 781-36B
Show/Hide
|
C23H21Cl2FN4O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0543444
|
N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C41H36N8O4
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0572512
|
N-[3-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C29H23N7O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0453900
|
5-((4-aminopiperidin-1-yl)methyl)-N-(1-((5-methylpyridin-3-yl)methyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H29N9
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0948510
|
1-(4-(3-hydroxyphenylamino)-9H-pyrido[2,3-b]indol-6-yl)ethanone
Show/Hide
|
C19H15N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0551545
|
N-[3-[4-(4-phenoxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C27H21N5O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0902790
|
4-{{5-(3-Acrylamidophenyl)-6-[4-(4-methylpiperazin-1-yl)-phenyl]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}amino}phenyl-2-(1-oxoisoindolin-2-yl)-2-phenylacetate
Show/Hide
|
C48H42N8O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0431411
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C22H22ClFN6O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0500333
|
N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C28H21ClFN5O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0500354
|
N-[5-[4-[(1-benzylindazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
|
C31H27N7O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0553718
|
N-[3-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C38H35ClN8O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0572511
|
N-[3-[4-ethoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0965630
|
N-{5-{4-{[3-Chloro-4-(pyridin-2-ylmethoxy)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-[(1-methoxypropan-2-yl)oxy]-phenyl}acrylamide
Show/Hide
|
C31H29ClN6O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0486641
|
N-[5-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-[2-(dimethylamino)ethoxy]phenyl]prop-2-enamide
Show/Hide
|
C31H30ClN7O3
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0570554
|
N-[5-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
|
C32H26N6O5
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0545156
|
(E)-N-[7-hydroxy-4-[3-methyl-4-([1,2,4]triazolo[4,3-b]pyridazin-7-yloxy)anilino]quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
Show/Hide
|
C28H27N9O3
|
1
|
| 1 |
IC50 = 16.01 nM
|
|
|
|
CP0432972
|
(E)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C27H27N7O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0369259
|
2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methoxy)acetic acid
Show/Hide
|
C23H19FN6O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0511625
|
5-[(4-aminopiperidin-1-yl)methyl]-N-[3-chloro-4-[(1-oxidopyridin-1-ium-2-yl)methoxy]phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H26ClN7O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0406561
|
cyclopentyl-[4-[2-methyl-4-[(6-morpholin-4-ylpyrido[3,4-d]pyrimidin-4-yl)amino]phenoxy]piperidin-1-yl]methanone
Show/Hide
|
C29H36N6O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0529791
|
N-tert-butyl-3-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
Show/Hide
|
C32H33N5O4
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0496951
|
2-piperazin-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H33N9O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0496952
|
(4-aminocyclohexyl) N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0435598
|
N-(2,6-difluorophenyl)-4-[4-[(6,7-dimethoxyquinazolin-4-yl)amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C29H29F2N5O4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0380016
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C33H35N7O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0432689
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C32H33N7O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0432974
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(3S,5R)-3,5-dimethylpiperazin-1-yl]but-2-enamide
Show/Hide
|
C34H38N8O2
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
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CP0469119
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-(2-methoxyethoxy)quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C34H38N8O3
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0432357
|
(4-amino-4-methylcyclohexyl) N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C30H34N8O2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0442803
|
(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C32H34ClFN6O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0049369
|
4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C30H34N6O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0406565
|
N-(2,6-difluorophenyl)-4-[4-[[6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C28H29F2N7O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0510451
|
[(3S)-morpholin-3-yl]methyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C28H30N8O3
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0578291
|
N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-propan-2-yloxy-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C29H32N6O2
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0452779
|
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H26ClN7O
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0227701
|
[(3S)-morpholin-3-yl]methyl N-[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
Show/Hide
|
C27H27FN8O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0418745
|
[(3S)-morpholin-3-yl]methyl N-[5-ethyl-4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C28H29FN8O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0038066
|
5-[(4-aminopiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H27FN8
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0435599
|
3,3-dimethyl-1-(4-(2-methyl-4-(6-morpholinopyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)piperidin-1-yl)butan-1-one
Show/Hide
|
C29H38N6O3
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0499123
|
piperidin-4-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0379993
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C33H36N8O2
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0572502
|
N-[2-[2-(dimethylamino)ethoxy]-5-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C34H31N7O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0445814
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[[6-(methylamino)pyrido[3,4-d]pyrimidin-4-yl]amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C27H27F2N7O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0409402
|
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyrazin-2-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C23H25ClN8O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0486567
|
N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-(2-methylpropoxy)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H34N6O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0537777
|
N-[3-[4-(4-benzhydryloxyanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C34H27N5O2
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0209615
|
5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H27FN8
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0439664
|
N-(2,6-difluorophenyl)-4-[4-[[6-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C30H31F2N5O4
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0374470
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C32H33N7O3
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0510452
|
2-piperidin-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C30H34N8O2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0501034
|
piperidin-3-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O2
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0948512
|
3-(6-bromo-9H-pyrido[2,3-b]indol-4-ylamino)phenol
Show/Hide
|
C17H12BrN3O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0564714
|
N-[3-[4-(4-benzylanilino)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C28H23N5O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0483697
|
4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-[3-(1H-imidazol-1-yl)propyl]pyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
|
C29H29N9O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0406560
|
4-(2-methyl-4-(6-(methylamino)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C27H30N6O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0499124
|
piperidin-2-ylmethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0374474
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[di(propan-2-yl)amino]but-2-enamide
Show/Hide
|
C34H39N7O2
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0406339
|
(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C32H32N6O4S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0467822
|
2-(1-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methyl)piperidin-4-ylamino)ethanol
Show/Hide
|
C28H31FN8O
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0452780
|
5-[(4-aminopiperidin-1-yl)methyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26ClFN6O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0432975
|
(E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-[di(propan-2-yl)amino]but-2-enamide
Show/Hide
|
C25H29ClFN5O2
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0453901
|
5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H27N9
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0511622
|
5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-2-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H27N9
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0374473
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C21H20ClFN6O2
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0511627
|
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-(pyridin-3-ylmethoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H26ClN7O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0384973
|
4-(2-methyl-4-(6-(pyrrolidin-1-yl)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C30H34N6O2
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0432356
|
2-piperidin-4-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C30H34N8O2
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0467823
|
5-[[4-(aminomethyl)piperidin-1-yl]methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0458760
|
(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C30H30N6O4S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0254994
|
2-(1H-imidazol-1-yl)ethyl N-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}carbamate
Show/Hide
|
C28H27N9O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0485462
|
4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylic acid
Show/Hide
|
C23H20N6O2
|
1
|
| 1 |
IC50 = 40 nM
|
|
|
|
CP0340906
|
N-[1-[(1R)-1-(3-fluorophenyl)ethyl]indazol-5-yl]-5-[[(2S)-morpholin-2-yl]methoxymethyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0484069
|
5-((1,4-diazepan-1-yl)methyl)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26ClFN6O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0406352
|
(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C26H24ClFN6O2
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0459842
|
5-[(4-aminopiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-6-methoxypyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8O
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0464652
|
5-[(4-amino-4-methylpiperidin-1-yl)methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0966165
|
N-{3-{6-[4-(4-Methylpiperazin-1-yl)phenyl]-4-{{4-[2-(1-oxoisoindolin-2-yl)-2-phenylacetamido]phenyl}amino}-7H-pyrrolo[2,3-d]-pyrimidin-5-yl}phenyl}acrylamide
Show/Hide
|
C48H43N9O3
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0496927
|
cyclopentyl-[4-[4-[[6-(2-methoxyethoxy)quinazolin-4-yl]amino]-2-methylphenoxy]piperidin-1-yl]methanone
Show/Hide
|
C29H36N4O4
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0494681
|
2-imidazol-1-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C28H27N9O2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0379992
|
(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C30H32N6O4S
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0486211
|
N-(2,6-difluorophenyl)-4-[4-[(6-methoxyquinazolin-4-yl)amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C28H27F2N5O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0153482
|
DACOMITINIB
Show/Hide
|
C24H25ClFN5O2
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0542302
|
4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C28H32N6O2
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0378419
|
EXEL-7647
Show/Hide
|
C24H25Cl2FN4O2
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0380390
|
2-(2-{[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}ethyl)-1H- isoindole-1,3(2H)-dione
Show/Hide
|
C25H18Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0380391
|
US9796704, Entry 216
Show/Hide
|
C22H21Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0380395
|
N-(3,4-dichlorophenyl)-7-{[(4-ethyl-1,4- oxazepan-2-yl)methyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0395755
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-4-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0415980
|
N-(3,4-dichlorophenyl)-7-{[(3S,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0445459
|
N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23ClF2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0452080
|
N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23BrCl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0458249
|
N-(3,4-dichlorophenyl)-7-[(hexahydro-1H- [1,4]oxazino[3,4-c][1,4]oxazin-3- ylmethyl)oxy]-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0458726
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-deoxy-D-xylo- hexitol
Show/Hide
|
C21H19BrClN3O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0461660
|
(3S,8aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
|
C23H22Cl2FN5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0464626
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
Show/Hide
|
C22H21BrClN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0464627
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-ethyl-L-iditol
Show/Hide
|
C23H23BrClN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0468537
|
1,4:3,6-dianhydro-5-deoxy-5-({[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol
Show/Hide
|
C23H23Cl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0473228
|
N-(3,4-dichlorophenyl)-7-{[(3R,8aR)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487677
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4- propyl-1,4-oxazepan-2- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487691
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2- (1-methylpiperidin-4-yl)-1,3-thiazol-4- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487692
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- piperidin-2-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H23Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487702
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-2-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0487718
|
N-(3,4-dichlorophenyl)-7-{[(3aR,6aS)-2- methyloctahydrocyclopenta[c]pyrrol-5- yl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H24Cl2N4O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487719
|
1,4:3,6-dianhydro-5-O-[4-[(3,4- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-2-O-methyl-D- xylo-hexitol
Show/Hide
|
C22H21Cl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487721
|
7-[(cyclopropylmethyl)oxy]-N-(3,4- dichlorophenyl)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C19H17Cl2N3O2
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0487722
|
US9796704, Entry 194
Show/Hide
|
C22H23Cl2N3O7
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0493314
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-4-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0493322
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- [(4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin- 2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H19Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0507993
|
N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23Cl2FN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0508004
|
N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H23Cl2FN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0508008
|
N-(3,4-dichlorophenyl)-7-({[5-(1- ethylpiperidin-3-yl)-1,2,4-oxadiazol-3- yl]methyl}oxy)-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C25H26Cl2N6O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0509854
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[3- (4-methylpiperazin-1-yl)-1,2,4-oxadiazol-5- yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0513211
|
1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]-5-O-methyl-L-iditol
Show/Hide
|
C22H21ClFN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0513288
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7- {[(3S,8aS)-hexahydro-1H-pyrrolo[2,1- c][1,4]oxazin-3-ylmethyl]oxy}-6- (methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0515482
|
N-(3,4-dichlorophenyl)-7-{[(3R,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0517548
|
1,4:3,6-dianhydro-5-deoxy-5-({[4-[(4,5- dichloro-2-fluorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-2-O- methyl-D-glucitol
Show/Hide
|
C23H22Cl2FN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0517550
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O- (difluoromethyl)-L-iditol
Show/Hide
|
C22H19BrClF2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0529534
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7- {[(8aR)-tetrahydro-1H-[1,3]thiazolo[4,3- c][1,4]oxazin-6-ylmethyl]oxy}quinazolin-4- amine
Show/Hide
|
C22H22Cl2N4O3S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0530868
|
6-[2-({[4-[(3,4-dichlorophenyl)amino]-6- (methyloxy)quinazolin-7- yl]oxy}methyl)morpholin-4-yl]hexanenitrile
Show/Hide
|
C26H29Cl2N5O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0539875
|
N-(3,4-dichlorophenyl)-7-{[(3S,8aS)- hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3- ylmethyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C23H24Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0551124
|
N-(3,4-dichlorophenyl)-7-{[(4-ethylmorpholin- 2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4- amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0856512
|
N-(3,4-dichlorophenyl)-6-[(1-methylethyl)oxy]-7-[(morpholin-2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0856517
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(1-methylpiperidin-3-yl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C25H25Cl2N5O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0867266
|
N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholine-4-carboximidamide
Show/Hide
|
C22H21Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0869467
|
2-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl]acetamide
Show/Hide
|
C22H23Cl2N5O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0869471
|
N-(3,4-dichlorophenyl)-6-(ethyloxy)-7-[(morpholin-2-ylmethyl)oxy]quinazolin-4-amine
Show/Hide
|
C21H22Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0869474
|
[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl](piperidin-1-yl)methylidene]cyanamide
Show/Hide
|
C27H29Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0869475
|
N-(3,4-dichlorophenyl)-7-{[(6,6-dimethylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869476
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4,6,6-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869477
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(methylsulfonyl)-L-iditol
Show/Hide
|
C22H21BrClN3O6S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869479
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-5-C-(trifluoromethyl)-D-glucitol
Show/Hide
|
C22H19BrClF3N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869480
|
1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-[(methylsulfonyl)amino]-L-iditol
Show/Hide
|
C22H22BrClN4O6S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869483
|
N-(3-chloro-2,4-difluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23ClF2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0869484
|
N-(4,5-dichloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2FN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0884372
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0884376
|
1,4:3,6-dianhydro-2-O-[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
|
C22H20Cl2FN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0884377
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
|
C22H20BrClFN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0893937
|
N-(3,4-dichlorophenyl)-7-({[4-(ethylsulfonyl)morpholin-2-yl]methyl}oxy)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O5S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0893940
|
N-(3,4-dichloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2FN4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0895616
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C24H24Cl2N6O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0895621
|
N-(3-chloro-2,4-difluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23ClF2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0895622
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0895699
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
|
C21H19BrClN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0897775
|
N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-{[(3S,4R)-4-(methyloxy)tetrahydroiuran-3-yl]oxy}quinazolin-4-amine
Show/Hide
|
C20H25N3O7
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0899591
|
{[(4-butylmorpholin-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0899593
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(methylsulfonyl)morpholin-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C21H22Cl2N4O5S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0900965
|
N-(4-bromo-3-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C22H25BrN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0900966
|
N-(3-chloro-2,4-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21ClF2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0900967
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-D-glucitol
Show/Hide
|
C21H19BrClN3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0902687
|
N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N-ethylmorpholine-4-carboximidamide
Show/Hide
|
C24H25Cl2N7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0903647
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2-(4,5,5-trimethylmorpholin-2-yl)ethyl]oxy}quinazolin-4-amine
Show/Hide
|
C24H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0903650
|
N-(3,4-dichloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H25Cl2FN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0912090
|
N-(3,4-dichlorophenyl)-7-{[(5-ethyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C24H25Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0912091
|
N-(4-bromo-2,3-dichlorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H25BrCl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0920903
|
7-[({4-[(3-chloropropyl)sulfonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H25Cl3N4O5S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0920904
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4-propanoylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H24Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0920905
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0920906
|
N-(4-bromo-2,5-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21BrF2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0920907
|
N-(3,4-dichloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21Cl2FN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0920909
|
N-(4,5-dichloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2FN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0920910
|
N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0921766
|
N-(3,4-dichloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23Cl2FN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0921771
|
dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-sorbose ethylene glycol acetal
Show/Hide
|
C23H21BrClN3O6
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0923157
|
N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-oxazepane-4-carboximidamide
Show/Hide
|
C23H23ClFN7O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
|
CP0923942
|
7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)-N-(3,4,5-trichlorophenyl)quinazolin-4-amine
Show/Hide
|
C21H21Cl3N4O3
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1
|
| 1 |
IC50 = 50 nM
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CP0923943
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N-(3,4-dichlorophenyl)-7-[({4-[(3,5-dimethylisoxazol-4-yl)carbonyl]morpholin-2-yl}methyl)oxy]-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H25Cl2N5O5
|
1
|
| 1 |
IC50 < 50 nM
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CP0923944
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N-(3,4-dichlorophenyl)-7-{[2-(5,5-dimethylmorpholin-2-yl)ethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H26Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0923945
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[2-(4,6,6-trimethylmorpholin-2-yl)ethyl]oxy}quinazolin-4-amine
Show/Hide
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C24H28Cl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0923946
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21BrClFN4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0923947
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(6S)-6-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-4-methylpiperazin-2-one
Show/Hide
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C21H20Cl2FN5O3
|
1
|
| 1 |
IC50 = 50 nM
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|
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CP0924120
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7-[({4-[(2-chloropyridin-3-yl)carbonyl]morpholin-2-yl}methyl)oxy]-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H22Cl3N5O4
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1
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| 1 |
IC50 < 50 nM
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CP0924123
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[(1E)-[2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)morpholin-4-yl](pyrrolidin-1-yl)methylidene]cyanamide
Show/Hide
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C26H27Cl2N7O3
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1
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| 1 |
IC50 < 50 nM
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CP0924133
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N'-cyano-2-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-N-methylmorpholine-4-carboximidamide
Show/Hide
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C24H26ClN7O3
|
1
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| 1 |
IC50 < 50 nM
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CP0924134
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N-(4-bromo-2,3-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21BrF2N4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0924135
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(6S)-6-({[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-4-methylpiperazin-2-one
Show/Hide
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C21H20BrClFN5O3
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1
|
| 1 |
IC50 = 50 nM
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CP0926169
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N-(4-bromo-3-chlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H22BrClN4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0926506
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7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)-N-(2,3,4-trichlorophenyl)quinazolin-4-amine
Show/Hide
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C21H21Cl3N4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0928848
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N-(3-bromo-4-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H25BrN4O3
|
1
|
| 1 |
IC50 = 50 nM
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|
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CP0928849
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7-{[(4-acetyl-1,4-oxazepan-2-yl)methyl]oxy}-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H24Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
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CP0930213
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1,4:3,6-dianhydro-5-O-[4-[(3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-fluoro-L-iditol
Show/Hide
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C21H18ClF2N3O4
|
1
|
| 1 |
IC50 = 50 nM
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CP0930214
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N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrClFN4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0930305
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N-(4-bromo-3-chloro-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24BrClN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0930306
|
N-(4-bromo-5-chloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H25BrClFN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
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CP0930307
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N-(4,5-dichloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25Cl2FN4O3
|
1
|
| 1 |
IC50 < 50 nM
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CP0938039
|
7-({[4-(cyclopentylcarbonyl)morpholin-2-yl]methyl}oxy)-N-(3,4-dichlorophenyl)-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C26H28Cl2N4O4
|
1
|
| 1 |
IC50 < 50 nM
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CP0938053
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N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-[(3R)-tetrahydrofuran-3-yloxy]quinazolin-4-amine
Show/Hide
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C19H17BrClN3O3
|
1
|
| 1 |
IC50 = 50 nM
|
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CP0942317
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N-(4,5-dichloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21Cl2FN4O3
|
1
|
| 1 |
IC50 = 50 nM
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CP0942462
|
1,4:3,6-dianhydro-5-O-[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-O-methyl-D-xylo-hexitol
Show/Hide
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C22H21Cl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
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CP0942584
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C21H21BrCl2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
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CP0942615
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N-(3,4-dichlorophenyl)-7-{[(4-ethanimidoyl-1,4-oxazepan-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H25Cl2N5O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0944880
|
N-(3,4-dichlorophenyl)-6-[(1-methylethyl)oxy]-7-{[(4-methylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H26Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0947311
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(5-methyl-4,5,6,7-tetrahydro[1,3]thiazolo[5,4-c]pyridin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H21Cl2N5O2S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0947313
|
N-(3-chloro-2,4-difluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C23H25ClF2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0952653
|
N-(4-bromo-5-chloro-2-fluorophenyl)-7-{[(3S,8aS)-hexahydro-1H-pyrrolo[2,1-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C23H23BrClFN4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0954969
|
N-(3,4-dichlorophenyl)-6-(ethyloxy)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0954970
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N-(4-bromo-3-chloro-2-fluorophenyl)-6-(methyloxy)-7-{[(4,5,5-trimethylmorpholin-2-yl)methyl]oxy}quinazolin-4-amine
Show/Hide
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C23H25BrClFN4O3
|
1
|
| 1 |
IC50 < 50 nM
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|
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CP0956988
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-C-(trifluoromethyl)-D-glucitol
Show/Hide
|
C22H18BrClF3N3O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0957821
|
1,4:3,6-dianhydro-2-O-[4-[(4-bromo-2,3-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
|
C22H20BrCl2N3O5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0958991
|
N-(3,4-dichlorophenyl)-6-(methyloxy)-7-({[4-(methylsulfonyl)-1,4-oxazepan-2-yl]methyl}oxy)quinazolin-4-amine
Show/Hide
|
C22H24Cl2N4O5S
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0961506
|
N-(4-bromo-3,5-difluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21BrF2N4O3
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0963485
|
N-(4-bromo-3-chloro-2-fluorophenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
|
C21H21BrClFN4O3
|
1
|
| 1 |
IC50 < 50 nM
|
|
|
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CP0964029
|
6-({[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-3,3,4-trimethylmorpholin-2-one
Show/Hide
|
C23H24Cl2N4O4
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
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CP0543416
|
N-[3-[4-methoxy-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C27H28N6O2
|
1
|
| 1 |
IC50 = 50 nM
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|
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CP0490486
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1-(4-(4-(6-(dimethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C27H36N6O2
|
1
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| 1 |
IC50 = 51 nM
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|
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CP0409406
|
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopyrrolidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H25FN8
|
1
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| 1 |
IC50 = 52 nM
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|
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CP0374477
|
(E)-N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C28H26ClFN6O2
|
1
|
| 1 |
IC50 = 53 nM
|
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CP0453899
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[[4-(methylamino)piperidin-1-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8
|
1
|
| 1 |
IC50 = 54 nM
|
|
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CP0038067
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(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H26FN7O2
|
1
|
| 1 |
IC50 = 55 nM
|
|
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CP0467956
|
N-(2,6-difluorophenyl)-4-[2-methyl-4-[[6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenoxy]piperidine-1-carboxamide
Show/Hide
|
C34H38F2N6O4
|
1
|
| 1 |
IC50 = 55 nM
|
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CP0568519
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N-[3-[4-[4-[(1,3-dioxoisoindol-2-yl)methyl]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C41H36N8O3
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
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CP0145851
|
(R)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H26FN7O2
|
1
|
| 1 |
IC50 = 60 nM
|
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CP0369258
|
5-(3-aminopropoxymethyl)-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H24FN7O
|
1
|
| 1 |
IC50 = 60 nM
|
|
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CP0452778
|
5-((4-aminopiperidin-1-yl)methyl)-N-(3-chloro-4-((5-methylpyridin-3-yl)methoxy)phenyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H28ClN7O
|
1
|
| 1 |
IC50 = 60 nM
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CP0004106
|
(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.1^{2,6}.0^{7,28}.0^{8,13}.0^{15,19}.0^{20,27}.0^{21,26}]nonacosa-8(13),9,11,14(28),15(19),20(27),21(26),22,24-nonaen-16-one
Show/Hide
|
C28H26N4O3
|
1
|
| 1 |
IC50 = 60.8 nM
|
|
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CP0374476
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C27H26N8O
|
1
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| 1 |
IC50 = 62 nM
|
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CP0431412
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C29H28N8O
|
1
|
| 1 |
IC50 = 62 nM
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|
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CP0571294
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(E)-N-[3-cyano-4-[3-methyl-4-([1,2,4]triazolo[4,3-c]pyrimidin-7-yloxy)anilino]quinolin-6-yl]-4-(dimethylamino)but-2-enamide
Show/Hide
|
C28H25N9O2
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1
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| 1 |
IC50 = 62.26 nM
|
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CP0487045
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N-(3-chlorophenyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C17H12ClN3
|
1
|
| 1 |
IC50 = 66 nM
|
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CP0358496
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-(piperidin-4-yloxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H26FN7O
|
1
|
| 1 |
IC50 = 70 nM
|
|
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CP0399584
|
(R)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((3-aminopyrrolidin-1-yl)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H25FN8
|
1
|
| 1 |
IC50 = 70 nM
|
|
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CP0431410
|
(E)-N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide
Show/Hide
|
C30H31N5O3
|
1
|
| 1 |
IC50 = 73 nM
|
|
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CP0486207
|
3,3-dimethyl-1-[4-[2-methyl-4-[[6-(3-morpholin-4-ylpropoxy)quinazolin-4-yl]amino]phenoxy]piperidin-1-yl]butan-1-one
Show/Hide
|
C33H45N5O4
|
1
|
| 1 |
IC50 = 75 nM
|
|
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CP0467824
|
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[(piperidin-4-ylamino)methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C26H27FN8
|
1
|
| 1 |
IC50 = 76 nM
|
|
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CP0406562
|
N-(2,6-difluorophenyl)-4-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]piperidine-1-carboxamide
Show/Hide
|
C33H32F2N6O4
|
1
|
| 1 |
IC50 = 76 nM
|
|
|
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CP0406564
|
4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C29H32N4O4
|
1
|
| 1 |
IC50 = 77 nM
|
|
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CP0486205
|
(4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)(cyclopentyl)methanone
Show/Hide
|
C32H42N4O6
|
1
|
| 1 |
IC50 = 77 nM
|
|
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CP0472044
|
2-morpholin-4-ylethyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethyl-7aH-pyrrolo[2,3-d]pyrimidin-6-yl]carbamate
Show/Hide
|
C29H32N8O3
|
1
|
| 1 |
IC50 = 77 nM
|
|
|
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CP0578290
|
N-[3-[3-ethyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C28H30N6O2
|
1
|
| 1 |
IC50 = 84 nM
|
|
|
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CP0187101
|
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C21H17FN6
|
1
|
| 1 |
IC50 = 88 nM
|
|
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CP0467076
|
(E)-N-[4-(3-chloro-4-fluoroanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C22H23ClFN7O
|
1
|
| 1 |
IC50 = 89 nM
|
|
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CP0060035
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5-(2-aminoethoxymethyl)-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C23H22FN7O
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
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CP0037987
|
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
Show/Hide
|
C22H23N3O4
|
5
|
| 1 |
IC50 = 91 nM
|
|
|
| 2 |
IC50 = 120 nM
|
|
|
| 3 |
IC50 = 140 nM
|
|
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| 4 |
IC50 = 160 nM
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| 5 |
IC50 = 200 nM
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CP0406563
|
N-[3-[4-[4-[1-(3,3-dimethylbutanoyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C32H39N5O4
|
1
|
| 1 |
IC50 = 94 nM
|
|
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CP0486568
|
N-[3-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-6-[4-(4-methylpiperazin-1-yl)phenyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
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C39H35ClFN7O2
|
1
|
| 1 |
IC50 = 95 nM
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CP0435600
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1-(4-(4-(6-methoxyquinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C27H34N4O3
|
1
|
| 1 |
IC50 = 96 nM
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CP0036082
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N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine
Show/Hide
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C22H24ClFN4O3
|
2
|
| 1 |
IC50 = 97 nM
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| 2 |
IC50 = 343 nM
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CP0496928
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1-(4-(4-(6,7-dimethoxyquinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C28H36N4O4
|
1
|
| 1 |
IC50 = 100 nM
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CP0380017
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(E)-N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C32H32N6O5S
|
1
|
| 1 |
IC50 = 100 nM
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CP0484469
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(E)-4-(dimethylamino)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
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C25H24N6O2
|
1
|
| 1 |
IC50 = 100 nM
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CP0464953
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(E)-N-[4-(4-phenoxyanilino)pyrido[3,4-d]pyrimidin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
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C27H26N6O2
|
1
|
| 1 |
IC50 = 102 nM
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CP0215424
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N-(1-benzylindazol-5-yl)-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C21H18N6
|
1
|
| 1 |
IC50 = 110 nM
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CP0309342
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2-((4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methoxy)acetamide
Show/Hide
|
C23H20FN7O2
|
1
|
| 1 |
IC50 = 110 nM
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CP0335787
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(4-(1-(3-fluorobenzyl)-1H-indazol-5-ylamino)pyrrolo[1,2-f][1,2,4]triazin-5-yl)methanol
Show/Hide
|
C21H17FN6O
|
1
|
| 1 |
IC50 = 110 nM
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CP0483696
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
|
C23H21N7O
|
1
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| 1 |
IC50 = 110 nM
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CP0452781
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5-[[4-(dimethylamino)piperidin-1-yl]methyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C28H31FN8
|
1
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| 1 |
IC50 = 110 nM
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CP0309328
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N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-(piperidin-4-ylmethoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O
|
1
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| 1 |
IC50 = 120 nM
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CP0511624
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N-[1-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-4-yl]-2-hydroxyacetamide
Show/Hide
|
C28H29FN8O2
|
1
|
| 1 |
IC50 = 120 nM
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CP0384975
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1-(4-(4-(6-(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C29H38N4O4
|
1
|
| 1 |
IC50 = 120 nM
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CP0432953
|
N-[4-[(1-benzylindol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C27H25N5O2
|
1
|
| 1 |
IC50 = 124 nM
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|
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CP0431408
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(2R,6S)-2,6-dimethylpiperidin-1-yl]but-2-enamide
Show/Hide
|
C35H39N7O2
|
1
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| 1 |
IC50 = 128 nM
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CP0357802
|
5-(((S)-morpholin-2-ylmethoxy)methyl)-N-(1-((R)-1-phenylethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29N7O2
|
1
|
| 1 |
IC50 = 130 nM
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CP0358497
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5-(4-aminobutoxymethyl)-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26FN7O
|
1
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| 1 |
IC50 = 130 nM
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|
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CP0456529
|
4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N-methylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
Show/Hide
|
C24H23N7O
|
1
|
| 1 |
IC50 = 130 nM
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|
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CP0445841
|
3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C33H35N5O4
|
1
|
| 1 |
IC50 = 130 nM
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CP0486204
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4-(2-methyl-4-(6-(4-methylpiperazin-1-yl)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C31H37N7O2
|
1
|
| 1 |
IC50 = 130 nM
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CP0144274
|
5-(((1,4-oxazepan-6-yl)methoxy)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O2
|
1
|
| 1 |
IC50 = 140 nM
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|
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CP0384972
|
4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-neopentylbenzamide
Show/Hide
|
C33H35N5O4
|
1
|
| 1 |
IC50 = 140 nM
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|
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CP0384976
|
3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-phenylbenzamide
Show/Hide
|
C34H29N5O4
|
1
|
| 1 |
IC50 = 140 nM
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|
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CP0471361
|
N-[3-[3-methyl-6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C27H28N6O2
|
1
|
| 1 |
IC50 = 146 nM
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|
|
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CP0486209
|
N-[3-[4-[4-[1-(cyclobutanecarbonyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C31H35N5O4
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
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CP0520421
|
N-[4-[(1-benzylindazol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C26H24N6O2
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
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CP0369257
|
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((piperidin-3-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0399775
|
benzyl N-[4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamate
Show/Hide
|
C30H27N7O2
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
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CP0511623
|
5-((1,4-diazepan-1-yl)methyl)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-6-methoxypyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H29FN8O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
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CP0406340
|
(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-morpholin-4-ylbut-2-enamide
Show/Hide
|
C30H32N6O5S
|
1
|
| 1 |
IC50 = 174 nM
|
|
|
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CP0485460
|
ethyl 4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C25H24N6O2
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
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CP0516402
|
N-[1-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-4-yl]acetamide
Show/Hide
|
C28H29FN8O
|
1
|
| 1 |
IC50 = 180 nM
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|
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CP0477196
|
2-[3-(1,3-benzodioxol-5-yl)-5-(4-bromophenyl)-3,4-dihydropyrazol-2-yl]-4-(4-bromophenyl)-1,3-thiazole
Show/Hide
|
C25H17Br2N3O2S
|
1
|
| 1 |
IC50 = 180 nM
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|
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CP0571434
|
N-[5-[4-[(2-benzyl-3H-benzimidazol-5-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-(2-hydroxyethoxy)phenyl]prop-2-enamide
Show/Hide
|
C31H27N7O3
|
1
|
| 1 |
IC50 = 188 nM
|
|
|
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CP0409404
|
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-[[4-(2-methylsulfonylethylamino)piperidin-1-yl]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C29H33FN8O2S
|
1
|
| 1 |
IC50 = 190 nM
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|
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CP0511633
|
5-((4-aminopiperidin-1-yl)methyl)-N-(1-(pyridin-4-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H27N9
|
1
|
| 1 |
IC50 = 190 nM
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|
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CP0467073
|
(E)-N-[4-[(1-benzylindazol-5-yl)amino]-7-ethoxyquinazolin-6-yl]-4-[(2S,6R)-2,6-dimethylpiperazin-1-yl]but-2-enamide
Show/Hide
|
C34H38N8O2
|
1
|
| 1 |
IC50 = 198 nM
|
|
|
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CP0399774
|
ethyl 4-[(1-benzylindazol-5-yl)amino]-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C24H22N6O2
|
1
|
| 1 |
IC50 = 200 nM
|
|
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CP0509089
|
ethyl 2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H23N7O3
|
1
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| 1 |
IC50 = 200 nM
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CP0456527
|
ethyl 4-[(1-benzylindazol-5-yl)amino]-5-propan-2-ylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C26H26N6O2
|
1
|
| 1 |
IC50 = 210 nM
|
|
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CP0384979
|
N-[3-[4-[4-[1-(3-chlorobenzoyl)piperidin-4-yl]oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C33H32ClN5O4
|
1
|
| 1 |
IC50 = 210 nM
|
|
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CP0435603
|
4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)-N-(2,6-difluorophenyl)piperidine-1-carboxamide
Show/Hide
|
C33H37F2N5O6
|
1
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| 1 |
IC50 = 230 nM
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CP0541868
|
N-cyclobutyl-3-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
Show/Hide
|
C32H31N5O4
|
1
|
| 1 |
IC50 = 230 nM
|
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CP0485715
|
3-(1H-imidazol-1-yl)propyl 4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxylate
Show/Hide
|
C29H28N8O2
|
1
|
| 1 |
IC50 = 240 nM
|
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CP0404829
|
2-cyano-N-[(2-hydroxy-5-morpholin-4-ylsulfonyl-1H-indol-3-yl)imino]acetamide
Show/Hide
|
C15H15N5O5S
|
1
|
| 1 |
IC50 = 240 nM
|
|
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CP0358495
|
5-methyl-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C20H17N7
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
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CP0364775
|
(S)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-6-methoxy-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C27H28FN7O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
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CP0467957
|
1-(4-(4-(6,7-bis(2-methoxyethoxy)quinazolin-4-ylamino)-2-methylphenoxy)piperidin-1-yl)-3,3-dimethylbutan-1-one
Show/Hide
|
C32H44N4O6
|
1
|
| 1 |
IC50 = 260 nM
|
|
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CP0374472
|
(E)-N-[7-ethoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C30H32N6O3
|
1
|
| 1 |
IC50 = 278 nM
|
|
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CP0358498
|
methyl 2-[[4-[[1-[(3-fluorophenyl)methyl]indazol-5-yl]amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methoxy]acetate
Show/Hide
|
C24H21FN6O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
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CP0529746
|
4-(2-methyl-4-(6-(2-morpholinoethylamino)pyrido[3,4-d]pyrimidin-4-ylamino)phenoxy)-N-neopentylbenzamide
Show/Hide
|
C32H39N7O3
|
1
|
| 1 |
IC50 = 280 nM
|
|
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CP0471252
|
N-[4-[[1-(benzenesulfonyl)indol-5-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C26H23N5O4S
|
1
|
| 1 |
IC50 = 286 nM
|
|
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CP0432690
|
(E)-N-[4-[4-(benzenesulfonamido)anilino]-7-ethoxyquinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
|
C31H35N7O4S
|
1
|
| 1 |
IC50 = 290 nM
|
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CP0954038
|
3-(6-(morpholinosulfonyl)-9H-pyrido[2,3-b]indol-4-ylamino)phenol
Show/Hide
|
C21H20N4O4S
|
1
|
| 1 |
IC50 = 298 nM
|
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CP0157746
|
5-methyl-N-(1-(pyridin-2-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C20H17N7
|
1
|
| 1 |
IC50 = 310 nM
|
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CP0734493
|
N-(4-chlorophenyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C17H12ClN3
|
1
|
| 1 |
IC50 = 310 nM
|
|
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CP0548169
|
N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-3-(2-methylpropyl)-4-oxo-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
Show/Hide
|
C30H34N6O2
|
1
|
| 1 |
IC50 = 321 nM
|
|
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CP0489638
|
1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C21H19ClN2O2S
|
1
|
| 1 |
IC50 = 350 nM
|
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|
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CP0427002
|
4-(Bis(2-chloroethyl)amino)-N-(1-naphthyl)benzamide
Show/Hide
|
C21H20Cl2N2O
|
1
|
| 1 |
IC50 = 350 nM
|
|
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CP0948511
|
3-(6-(4-(2-Hydroxyethyl)piperazin-1-ylsulfonyl)-9H-pyrido[2,3-b]indol-4-ylamino)-phenol
Show/Hide
|
C23H25N5O4S
|
1
|
| 1 |
IC50 = 376 nM
|
|
|
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CP0145858
|
(S)-5-((morpholin-2-ylmethoxy)methyl)-N-(1-(pyridin-2-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26N8O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
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CP0456526
|
ethyl 4-[(1-benzylindazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C23H20N6O2
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
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CP0898280
|
N-(3-Methoxyphenyl)-6-(piperazin-1-yl-sulfonyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C22H23N5O3S
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
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CP0379989
|
N-[7-methoxy-4-(4-phenylmethoxyanilino)quinazolin-6-yl]propanamide
Show/Hide
|
C25H24N4O3
|
1
|
| 1 |
IC50 = 404 nM
|
|
|
|
CP0432954
|
N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
|
C18H16ClFN4O2
|
1
|
| 1 |
IC50 = 406 nM
|
|
|
|
CP0157693
|
(S)-5-((morpholin-2-ylmethoxy)methyl)-N-(1-(pyridin-3-ylmethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
Show/Hide
|
C25H26N8O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0427003
|
4-(Bis(2-chloroethyl)amino)-N-(4-methoxyphenyl)benzamide
Show/Hide
|
C18H20Cl2N2O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0431358
|
(E)-N-[7-methoxy-4-[4-(pyridin-2-ylmethyl)anilino]quinazolin-6-yl]-4-pyrrolidin-1-ylbut-2-enamide
Show/Hide
|
C29H30N6O2
|
1
|
| 1 |
IC50 = 413 nM
|
|
|
|
CP0476116
|
N-[7-methoxy-4-(4-phenoxyanilino)quinazolin-6-yl]propanamide
Show/Hide
|
C24H22N4O3
|
1
|
| 1 |
IC50 = 419 nM
|
|
|
|
CP0060097
|
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C22H19FN6O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0296492
|
N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]-5-(2-methoxyethoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
|
C24H23FN6O2
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0859705
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2-(2-(5-Bromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
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C10H8BrN3O2S
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1
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| 1 |
IC50 = 420 nM
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CP0177513
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N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-amine
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C20H16ClFN4O
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1
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| 1 |
IC50 = 430 nM
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CP0465177
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N-[4-[3-chloro-4-[(3-fluorophenyl)methoxy]anilino]-7-methoxyquinazolin-6-yl]propanamide
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C25H22ClFN4O3
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1
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| 1 |
IC50 = 458 nM
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CP0433488
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4-(4-bromophenyl)-2-[5-(4-bromophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-3,4-dihydropyrazol-2-yl]-1,3-thiazole
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C26H19Br2N3O2S
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1
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| 1 |
IC50 = 460 nM
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CP0436087
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4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethyl-N,N-dimethylpyrrolo[1,2-a][1,2,4]triazine-6-carboxamide
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C25H25N7O
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1
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| 1 |
IC50 = 500 nM
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CP0445873
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N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]propanamide
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C24H27ClFN5O3
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1
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| 1 |
IC50 = 509 nM
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CP0369261
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N-[1-[(1S)-1-(3-fluorophenyl)ethyl]indazol-5-yl]-5-[[(2S)-morpholin-2-yl]methoxymethyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
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C27H28FN7O2
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1
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| 1 |
IC50 = 510 nM
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CP0384978
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2-methoxy-N-[3-(4-{3-methyl-4-[1-(tetrahydro-furan-2-carbonyl)-piperidin-4-yloxy]-phenylamino}-quinazolin-6-yl)-prop-2-ynyl]-acetamide
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C31H35N5O5
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1
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| 1 |
IC50 = 550 nM
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CP0467071
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N-[4-[(1-benzyl-2,3-dihydroindol-5-yl)amino]-7-methoxyquinazolin-6-yl]propanamide
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C27H27N5O2
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1
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| 1 |
IC50 = 556 nM
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CP0145853
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5-[3-(dimethylamino)propoxymethyl]-N-[1-[(3-fluorophenyl)methyl]indazol-5-yl]pyrrolo[2,1-f][1,2,4]triazin-4-amine
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C26H28FN7O
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1
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| 1 |
IC50 = 560 nM
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CP0364773
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(S)-N-(4-(3-fluorobenzyloxy)-3-chlorophenyl)-5-((morpholin-2-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
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C25H25ClFN5O3
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1
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| 1 |
IC50 = 560 nM
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CP0913983
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N-(3-Ethoxyphenyl)-6-(piperazin-1-yl-sulfonyl)-9H-pyrido[2,3-b]indol-4-amine
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C23H25N5O3S
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1
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| 1 |
IC50 = 576 nM
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CP0144278
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(R)-N-(1-(3-fluorobenzyl)-1H-indazol-5-yl)-5-((morpholin-3-ylmethoxy)methyl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
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C26H26FN7O2
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1
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| 1 |
IC50 = 590 nM
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CP0552871
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N-[3-[6-[4-(4-methylpiperazin-1-yl)phenyl]-4-oxo-3-propan-2-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl]phenyl]prop-2-enamide
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C29H32N6O2
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1
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| 1 |
IC50 = 592 nM
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CP0432692
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N-[7-methoxy-4-[[1-(pyridin-2-ylmethyl)indol-5-yl]amino]quinazolin-6-yl]propanamide
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C26H24N6O2
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1
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| 1 |
IC50 = 642 nM
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CP0489639
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1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
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C21H19BrN2O2S
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1
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| 1 |
IC50 = 660 nM
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CP0439402
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2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetic acid
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C24H22N6O2
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1
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| 1 |
IC50 = 680 nM
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CP0908158
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2-(4-(4-(3-Methoxyphenylamino)-9H-pyrido[2,3-b]indol-6-ylsulfonyl)piperazin-1-yl)ethanol
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C24H27N5O4S
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1
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| 1 |
IC50 = 689 nM
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CP0432588
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[4-[(1-benzylindazol-5-yl)amino]-5-ethylpyrrolo[2,1-f][1,2,4]triazin-6-yl]methanol
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C23H22N6O
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1
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| 1 |
IC50 = 730 nM
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CP0380019
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N-[4-[[1-(furan-2-ylmethyl)indol-5-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
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C25H23N5O3
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1
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| 1 |
IC50 = 782 nM
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CP0431424
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N-[4-[4-(benzenesulfonamido)anilino]-7-methoxyquinazolin-6-yl]propanamide
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C24H23N5O4S
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1
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| 1 |
IC50 = 798 nM
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CP0379899
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ethyl 2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
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C27H25N7O4
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1
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| 1 |
IC50 = 800 nM
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CP0406338
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N-[4-(1H-indol-5-ylamino)-7-methoxyquinazolin-6-yl]propanamide
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C20H19N5O2
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1
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| 1 |
IC50 = 800 nM
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CP0473244
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N-[7-methoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]propanamide
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C24H23N5O3
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1
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| 1 |
IC50 = 815 nM
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CP0483694
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ethyl 5-ethyl-4-(4-phenoxyanilino)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
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C23H22N4O3
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1
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| 1 |
IC50 = 820 nM
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CP0335791
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5-(((S)-morpholin-2-ylmethoxy)methyl)-N-(1-((S)-1-phenylethyl)-1H-indazol-5-yl)pyrrolo[1,2-f][1,2,4]triazin-4-amine
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C27H29N7O2
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1
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| 1 |
IC50 = 850 nM
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CP0379650
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2-[3-(1,3-benzodioxol-5-yl)-5-(4-bromophenyl)-3,4-dihydropyrazol-2-yl]-4-(4-methoxyphenyl)-1,3-thiazole
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C26H20BrN3O3S
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1
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| 1 |
IC50 = 850 nM
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CP0478911
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N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]acetamide
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C27H18ClF3N4O2S
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1
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| 1 |
IC50 = 879 nM
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CP0432973
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N-[7-methoxy-4-[[1-(pyridin-2-ylmethyl)-2,3-dihydroindol-5-yl]amino]quinazolin-6-yl]propanamide
Show/Hide
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C26H26N6O2
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1
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| 1 |
IC50 = 897 nM
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CP0458759
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N-[4-[[6-(benzenesulfonamido)pyridin-3-yl]amino]-7-methoxyquinazolin-6-yl]propanamide
Show/Hide
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C23H22N6O4S
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1
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| 1 |
IC50 = 958 nM
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CP0841942
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N-o-Tolyl-9H-pyrido[2,3-b]indol-4-amine
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C18H15N3
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1
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| 1 |
IC50 = 978 nM
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CP0861439
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1-(4-(3-nitrophenylamino)-9H-pyrido[2,3-b]indol-6-yl)ethanone
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C19H14N4O3
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1
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| 1 |
IC50 = 978 nM
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CP0380385
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(3S,9aS)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one
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C24H24Cl2FN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0380386
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(3S,8aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
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C23H22Cl2FN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0380387
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1,4:3,6-dianhydro-2-O-[4-[(3-bromo-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
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C23H24BrN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0458250
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3- chlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-D- glucitol
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C22H21BrClN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0487699
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1,4:3,6-dianhydro-5-({[4-[(4-bromo-2,3- dichlorophenyl)amino]-6- (methyloxy)quinazolin-7-yl]oxy}methyl)-5- deoxy-2-O-methyl-D-glucitol
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C23H22BrCl2N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0493312
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1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2- methylphenyl)amino]-6- (methyloxy)quinazolin-7-yl]-5-O-methyl-L- iditol
Show/Hide
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C23H24ClN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0493313
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N-(3,4-dichlorophenyl)-6-(methyloxy)-7-{[(2- morpholin-4-yl-1,3-thiazol-4- yl)methyl]oxy}quinazolin-4-amine
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C23H21Cl2N5O3S
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1
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| 1 |
IC50 = 1000 nM
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CP0517549
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(3S,8aS)-3-({[4-[(4-bromo-3-chloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydropyrrolo[1,2- a]pyrazin-1(2H)-one
Show/Hide
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C23H22BrClFN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0545604
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(3S,9aR)-3-({[4-[(3,4-dichloro-2- fluorophenyl)amino]-6-(methyloxy)quinazolin- 7-yl]oxy}methyl)hexahydro-2H-pyrido[1,2- a]pyrazin-1(6H)-one
Show/Hide
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C24H24Cl2FN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0848456
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(3S,8aS)-3-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-2-methylhexahydropyrrolo[1,2-a]pyrazin-1(2H)-one
Show/Hide
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C24H24Cl2FN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0848458
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1,4:3,6-dianhydro-2-O-[4-[(4,5-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
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C22H20Cl2FN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0856499
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1,1-dimethylethyl 2-(2-{[4-[(3,4-dichlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}ethyl)-5,5-dimethylmorpholine-4-carboxylate
Show/Hide
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C28H34Cl2N4O5
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1
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| 1 |
IC50 = 1000 nM
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CP0856508
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(3R,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C24H25BrCl2N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0869478
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(diethylamino)-L-iditol
Show/Hide
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C25H28BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0869481
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1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-[4-{[3-fluoro-4-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
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C26H29F2N5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0869482
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1,4:3,6-dianhydro-2-deoxy-5-O-[4-{[2,3-dichloro-4-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-2-fluoro-L-iditol
Show/Hide
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C26H28Cl2FN5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0870274
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-morpholin-4-yl-L-iditol
Show/Hide
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C25H26BrClN4O5
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1
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| 1 |
IC50 = 1000 nM
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CP0870278
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1,4:3,6-dianhydro-2-deoxy-5-O-[4-{[3,4-dichloro-2-(4-methylpiperazin-1-yl)phenyl]amino}-6-(methyloxy)quinazolin-7-yl]-2-fluoro-L-iditol
Show/Hide
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C26H28Cl2FN5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0893939
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N-(4-bromo-3-chlorophenyl)-6-(methyloxy)-7-[(1-methylpyrrolidin-3-yl)oxy]quinazolin-4-amine
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C20H20BrClN4O2
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1
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| 1 |
IC50 = 1000 nM
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CP0895700
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2-amino-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-L-iditol
Show/Hide
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C21H20BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0901757
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N-(3,4-dichloro-2-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0902688
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N-(2,3-dichloro-4-methylphenyl)-7-{[(4-methylmorpholin-2-yl)methyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C22H24Cl2N4O3
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1
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| 1 |
IC50 = 1000 nM
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CP0902689
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(4-methylpiperazin-1-yl)-L-iditol
Show/Hide
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C26H29BrClN5O4
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1
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| 1 |
IC50 = 1000 nM
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CP0903651
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2-O-acetyl-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-L-iditol
Show/Hide
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C23H21BrClN3O6
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1
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| 1 |
IC50 = 1000 nM
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CP0912075
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-(methylsulfonyl)-D-glucitol
Show/Hide
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C22H21BrClN3O7S
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1
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| 1 |
IC50 = 1000 nM
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CP0912092
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(6S)-6-({[4-[(3,4-dichloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-dimethylpiperazin-2-one
Show/Hide
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C22H22Cl2FN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0920908
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-S-methyl-5-thio-L-iditol
Show/Hide
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C22H21BrClN3O4S
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1
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| 1 |
IC50 = 1000 nM
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CP0921768
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1,4:3,6-dianhydro-2-O-methyl-5-O-{6-(methyloxy)-4-[(2,3,4-trichlorophenyl)amino]quinazolin-7-yl}-L-iditol
Show/Hide
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C22H20Cl3N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0923756
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1,4:3,6-dianhydro-2-O-[4-[(4-bromo-5-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-y1]-5-O-methyl-L-iditol
Show/Hide
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C22H20BrClFN3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0924136
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-(dimethylamino)-L-iditol
Show/Hide
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C22H22BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0924137
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2-(acetylamino)-1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-L-iditol
Show/Hide
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C23H22BrClN4O5
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1
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| 1 |
IC50 = 1000 nM
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CP0930308
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-pyrrolidin-1-yl-L-iditol
Show/Hide
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C25H26BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0930309
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1,4:3,6-dianhydro-5-O-[4-[(4-bromo-3-chlorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-2-deoxy-2-piperidin-1-yl-L-iditol
Show/Hide
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C26H28BrClN4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0947314
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N-(4-bromo-2,3-dichlorophenyl)-7-{[(3S,9aS)-hexahydro-1H-[1,4]oxazino[3,4-c][1,4]oxazin-3-ylmethyl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C23H23BrCl2N4O4
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1
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| 1 |
IC50 = 1000 nM
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CP0947315
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1,4:3,6-dianhydro-2-O-[4-[(3-chloro-2,4-difluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]-5-O-methyl-L-iditol
Show/Hide
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C22H20ClF2N3O5
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1
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| 1 |
IC50 = 1000 nM
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CP0952649
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(6S)-6-({[4-[(4-bromo-3-chloro-2-fluorophenyl)amino]-6-(methyloxy)quinazolin-7-yl]oxy}methyl)-1,4-dimethylpiperazin-2-one
Show/Hide
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C22H22BrClFN5O3
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1
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| 1 |
IC50 = 1000 nM
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CP0957482
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N-(4-bromo-3-chlorophenyl)-7-{[(3a'S,4R,6'S,6a'R)-2,2-dimethyltetrahydrospiro[1,3-dioxolane-4,3'-furo [3,2-b]iuran]-6'-yl]oxy}-6-(methyloxy)quinazolin-4-amine
Show/Hide
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C25H23BrClN3O6
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1
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| 1 |
IC50 = 1000 nM
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CP0963407
|
1,4:3,6-dianhydro-2-deoxy-2-fluoro-5-O-(6-(methyloxy)-4-{[4-(4-methylpiperazin-1-yl)phenyl]amino}quinazolin-7-yl)-L-iditol
Show/Hide
|
C26H30FN5O4
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0878675
|
2-(5-(4-Bromophenyl)-3-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3OS
|
1
|
| 1 |
IC50 = 1070 nM
|
|
|
|
CP0861442
|
6-bromo-N-(3-chlorophenyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C17H11BrClN3
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0913981
|
1-(4-(3-chlorophenylamino)-9H-pyrido[2,3-b]indol-6-yl)ethanone
Show/Hide
|
C19H14ClN3O
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0456528
|
ethyl 4-[(1-benzylindazol-5-yl)amino]-5-propylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C26H26N6O2
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0444135
|
1-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]-3-(2-morpholin-4-ylethyl)urea
Show/Hide
|
C32H28ClF3N6O3S
|
1
|
| 1 |
IC50 = 1200 nM
|
|
|
|
CP0430870
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C21H18Cl2N2O2S
|
1
|
| 1 |
IC50 = 1230 nM
|
|
|
|
CP0875725
|
N-(3-Methoxyphenyl)-(6-morpholinosulfonyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C22H22N4O4S
|
1
|
| 1 |
IC50 = 1240 nM
|
|
|
|
CP0116655
|
3-(9H-pyrido[2,3-b]indol-4-ylamino)phenol
Show/Hide
|
C17H13N3O
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0443293
|
2-[5-(4-bromophenyl)-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-3,4-dihydropyrazol-2-yl]-4-(4-methoxyphenyl)-1,3-thiazole
Show/Hide
|
C27H22BrN3O3S
|
1
|
| 1 |
IC50 = 1320 nM
|
|
|
|
CP0446377
|
1-benzyl-N-[6-(ethoxymethyl)-5-ethylpyrrolo[1,2-a][1,2,4]triazin-4-yl]-1H-indazol-5-amine
Show/Hide
|
C25H26N6O
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0489636
|
1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H18ClFN2OS
|
1
|
| 1 |
IC50 = 1410 nM
|
|
|
|
CP0514142
|
6-(4-aminophenyl)-N-[3-chloro-4-[3-(trifluoromethyl)phenoxy]phenyl]thieno[2,3-d]pyrimidin-4-amine
Show/Hide
|
C25H16ClF3N4OS
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0848111
|
1-(4-(3-Aminophenylamino)-9H-pyrido[2,3-b]indol-6-yl)ethanone
Show/Hide
|
C19H16N4O
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0853154
|
2-(2-(5-Chloro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8ClN3O2S
|
1
|
| 1 |
IC50 = 1780 nM
|
|
|
|
CP0429957
|
1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H18BrFN2OS
|
1
|
| 1 |
IC50 = 1870 nM
|
|
|
|
CP0383875
|
4-(Bis(2-chloroethyl)amino)-N-p-tolylbenzamide
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 1880 nM
|
|
|
|
CP0543150
|
methyl 2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C25H21N7O3
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0481743
|
methyl 2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H23N7O4
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0198957
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-phenyl)acrylate
Show/Hide
|
C21H19N3O4
|
1
|
| 1 |
IC50 = 2150 nM
|
|
|
|
CP0447436
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H18Cl2N2O3
|
1
|
| 1 |
IC50 = 2210 nM
|
|
|
|
CP0473489
|
2-[3-(1,3-benzodioxol-5-yl)-5-(4-methylphenyl)-3,4-dihydropyrazol-2-yl]-4-(4-bromophenyl)-1,3-thiazole
Show/Hide
|
C26H20BrN3O2S
|
1
|
| 1 |
IC50 = 2230 nM
|
|
|
|
CP0376571
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C21H18Br2N2O2S
|
1
|
| 1 |
IC50 = 2240 nM
|
|
|
|
CP0847129
|
2-(5-Phenyl-3-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3OS
|
1
|
| 1 |
IC50 = 2240 nM
|
|
|
|
CP0415407
|
1-(5-Chloro-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H19ClN2O3
|
1
|
| 1 |
IC50 = 2270 nM
|
|
|
|
CP0521413
|
4-(Bis(2-chloroethyl)amino)-N-(4-isopropylphenyl)benzamide
Show/Hide
|
C20H24Cl2N2O
|
1
|
| 1 |
IC50 = 2320 nM
|
|
|
|
CP0409226
|
2-[3-(1,3-benzodioxol-5-yl)-5-(4-chlorophenyl)-3,4-dihydropyrazol-2-yl]-4-(4-bromophenyl)-1,3-thiazole
Show/Hide
|
C25H17BrClN3O2S
|
1
|
| 1 |
IC50 = 2380 nM
|
|
|
|
CP0483470
|
2-{4-[(1-benzyl-1H-indazol-5-yl)amino]-5-ethylpyrrolo[1,2-a][1,2,4]triazin-6-yl}acetamide
Show/Hide
|
C24H23N7O
|
1
|
| 1 |
IC50 = 2400 nM
|
|
|
|
CP0913242
|
2-(2-(4-Bromobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8BrN3OS
|
1
|
| 1 |
IC50 = 2430 nM
|
|
|
|
CP0847122
|
2-(3,5-Dip-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3OS
|
1
|
| 1 |
IC50 = 2520 nM
|
|
|
|
CP0520439
|
4-(Bis(2-chloroethyl)amino)-N-(4-bromophenyl)benzamide
Show/Hide
|
C17H17BrCl2N2O
|
1
|
| 1 |
IC50 = 2580 nM
|
|
|
|
CP0489670
|
1-(5-Bromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H19BrN2O3
|
1
|
| 1 |
IC50 = 2660 nM
|
|
|
|
CP0859406
|
2-(2-(4-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8ClN3OS
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0847109
|
2-(5-(4-Bromophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3O2S
|
1
|
| 1 |
IC50 = 2750 nM
|
|
|
|
CP0483691
|
ethyl 4-(3-chloro-4-fluoroanilino)-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C17H16ClFN4O2
|
1
|
| 1 |
IC50 = 2800 nM
|
|
|
|
CP0399771
|
ethyl 4-(3-bromoanilino)-5-ethylpyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C17H17BrN4O2
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0847124
|
2-(5-(4-Bromophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14BrN3OS
|
1
|
| 1 |
IC50 = 3050 nM
|
|
|
|
CP0847108
|
2-(5-(4-Chlorophenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3OS
|
1
|
| 1 |
IC50 = 3110 nM
|
|
|
|
CP0483692
|
ethyl 5-ethyl-4-(1H-indazol-5-ylamino)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C18H18N6O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0383873
|
4-(Bis(2-chloroethyl)amino)-N-(4-chlorophenyl)benzamide
Show/Hide
|
C17H17Cl3N2O
|
1
|
| 1 |
IC50 = 3330 nM
|
|
|
|
CP0440140
|
1-(5-Chloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H18ClFN2O2
|
1
|
| 1 |
IC50 = 3450 nM
|
|
|
|
CP0514949
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-(benzyloxy)phenyl)acrylate
Show/Hide
|
C22H21N3O5
|
1
|
| 1 |
IC50 = 3460 nM
|
|
|
|
CP0897862
|
2-(5-(4-Fluorophenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3OS
|
1
|
| 1 |
IC50 = 3530 nM
|
|
|
|
CP0006184
|
6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione
Show/Hide
|
C14H6O8
|
1
|
| 1 |
IC50 = 3540 nM
|
|
|
|
CP0859405
|
2-(2-(5-Fluoro-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8FN3O2S
|
1
|
| 1 |
IC50 = 3590 nM
|
|
|
|
CP0910691
|
2-(3,5-Bis(4-bromophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13Br2N3OS
|
1
|
| 1 |
IC50 = 3650 nM
|
|
|
|
CP0880338
|
2-(2-(3,5-Dibromo-2-hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H7Br2N3O2S
|
1
|
| 1 |
IC50 = 3730 nM
|
|
|
|
CP0847120
|
2-(5-(4-Bromophenyl)-3-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrClN3OS
|
1
|
| 1 |
IC50 = 3840 nM
|
|
|
|
CP0845353
|
2-(2-(4-Fluorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8FN3OS
|
1
|
| 1 |
IC50 = 3890 nM
|
|
|
|
CP0498688
|
4-(Bis(2-chloroethyl)amino)-N-(4-fluorophenyl)benzamide
Show/Hide
|
C17H17Cl2FN2O
|
1
|
| 1 |
IC50 = 3890 nM
|
|
|
|
CP0481744
|
ethyl 2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C27H25N7O3
|
1
|
| 1 |
IC50 = 4100 nM
|
|
|
|
CP0853322
|
2-(3-(4-Methoxyphenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3O2S
|
1
|
| 1 |
IC50 = 4120 nM
|
|
|
|
CP0373905
|
(E)-2-((E)-(3,5-Dichloro-2-hydroxybenzylidene)hydrazono)thiazolidin-4-one (5)
Show/Hide
|
C10H7Cl2N3O2S
|
1
|
| 1 |
IC50 = 4510 nM
|
|
|
|
CP0176037
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C21H18Br2N2O3
|
1
|
| 1 |
IC50 = 4530 nM
|
|
|
|
CP0910690
|
2-(3-Phenyl-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3OS
|
1
|
| 1 |
IC50 = 4640 nM
|
|
|
|
CP0428346
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-bromophenyl)acrylate
Show/Hide
|
C15H14BrN3O4
|
1
|
| 1 |
IC50 = 4650 nM
|
|
|
|
CP0411851
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-chlorophenyl)acrylate
Show/Hide
|
C15H14ClN3O4
|
1
|
| 1 |
IC50 = 4770 nM
|
|
|
|
CP0868127
|
2-(5-(4-Chlorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14ClN3OS
|
1
|
| 1 |
IC50 = 4830 nM
|
|
|
|
CP0878673
|
2-(3-(4-Bromophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14BrN3OS
|
1
|
| 1 |
IC50 = 4870 nM
|
|
|
|
CP0411850
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-1-yl)acrylate
Show/Hide
|
C19H17N3O4
|
1
|
| 1 |
IC50 = 5030 nM
|
|
|
|
CP0848283
|
2-(3,5-Diphenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H15N3OS
|
1
|
| 1 |
IC50 = 5120 nM
|
|
|
|
CP0539409
|
1-(5-Bromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H18BrFN2O2
|
1
|
| 1 |
IC50 = 5170 nM
|
|
|
|
CP0460317
|
2-amino-5-oxo-1-pyridin-3-yl-4-(tetrazolo[1,5-a]quinolin-4-yl)-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C24H18N8O
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0509090
|
methyl 2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H23N7O3
|
1
|
| 1 |
IC50 = 5200 nM
|
|
|
|
CP0853155
|
2-(2-(4-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3OS
|
1
|
| 1 |
IC50 = 5830 nM
|
|
|
|
CP0427703
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-fluorophenyl)acrylate
Show/Hide
|
C15H14FN3O4
|
1
|
| 1 |
IC50 = 5840 nM
|
|
|
|
CP0878674
|
2-(3-(4-Bromophenyl)-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrClN3OS
|
1
|
| 1 |
IC50 = 5870 nM
|
|
|
|
CP0847125
|
2-(5-(4-Methoxyphenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H17N3O2S
|
1
|
| 1 |
IC50 = 6210 nM
|
|
|
|
CP0897863
|
2-(5-(4-Methoxyphenyl)-3-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3O2S
|
1
|
| 1 |
IC50 = 6230 nM
|
|
|
|
CP0921415
|
2-(5-(4-Bromophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrFN3OS
|
1
|
| 1 |
IC50 = 6240 nM
|
|
|
|
CP0921414
|
2-(5-(4-Fluorophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14FN3OS
|
1
|
| 1 |
IC50 = 6350 nM
|
|
|
|
CP0491206
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H17Cl2FN2OS
|
1
|
| 1 |
IC50 = 6490 nM
|
|
|
|
CP0913982
|
2-(4-(4-(3-Ethoxyphenylamino)-9H-pyrido[2,3-b]indol-6-ylsulfonyl)piperazin-1-yl)ethanol
Show/Hide
|
C25H29N5O4S
|
1
|
| 1 |
IC50 = 6530 nM
|
|
|
|
CP0491207
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylthiourea
Show/Hide
|
C21H17Br2FN2OS
|
1
|
| 1 |
IC50 = 6730 nM
|
|
|
|
CP0885035
|
2-(2-(4-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H9N3O2S
|
1
|
| 1 |
IC50 = 6930 nM
|
|
|
|
CP0918021
|
2-(3-(4-bromophenyl)-5-p-tolyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3OS
|
1
|
| 1 |
IC50 = 7040 nM
|
|
|
|
CP0899898
|
2-(3-(4-Chlorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14ClN3OS
|
1
|
| 1 |
IC50 = 7050 nM
|
|
|
|
CP0429966
|
1-(2-Hydroxy-5-methylbenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C22H22N2O2S
|
1
|
| 1 |
IC50 = 7130 nM
|
|
|
|
CP0483693
|
4-Benzylamino-5-ethyl-pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid ethyl ester
Show/Hide
|
C18H20N4O2
|
1
|
| 1 |
IC50 = 7200 nM
|
|
|
|
CP0853520
|
2-(3-(4-Methoxyphenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3O2S
|
1
|
| 1 |
IC50 = 7350 nM
|
|
|
|
CP0885544
|
2-(5-(4-Chlorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3O2S
|
1
|
| 1 |
IC50 = 7590 nM
|
|
|
|
CP0860905
|
2-(5-(4-Fluorophenyl)-3-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3O2S
|
1
|
| 1 |
IC50 = 8040 nM
|
|
|
|
CP0878669
|
2-(3-(4-Chlorophenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3OS
|
1
|
| 1 |
IC50 = 8130 nM
|
|
|
|
CP0885543
|
2-(3-(4-Bromophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13BrFN3OS
|
1
|
| 1 |
IC50 = 8140 nM
|
|
|
|
CP0447434
|
(E)-2((E)-(4-Nitrobenzylidene)hydrazono)thiazolidine-4-one (2)
Show/Hide
|
C10H8N4O3S
|
1
|
| 1 |
IC50 = 8460 nM
|
|
|
|
CP0875722
|
6-bromo-N-(3-nitrophenyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C17H11BrN4O2
|
1
|
| 1 |
IC50 = 8830 nM
|
|
|
|
CP0379898
|
2-amino-4-(7-methoxytetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C25H20N8O2
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0483737
|
methyl 2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C25H20ClN7O3
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0859407
|
2-(2-(4-Methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3O2S
|
1
|
| 1 |
IC50 = 9170 nM
|
|
|
|
CP0418466
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(naphthalen-2-yl)acrylate
Show/Hide
|
C19H17N3O4
|
1
|
| 1 |
IC50 = 9240 nM
|
|
|
|
CP0918022
|
2-(3-(4-Bromophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16BrN3O2S
|
1
|
| 1 |
IC50 = 9270 nM
|
|
|
|
CP0406247
|
1-(2-Hydroxy-3,5-dimethylbenzyl)-1-(4-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C23H24N2O2S
|
1
|
| 1 |
IC50 = 9470 nM
|
|
|
|
CP0401471
|
1-(3,5-Dichloro-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H17Cl2FN2O2
|
1
|
| 1 |
IC50 = 9640 nM
|
|
|
|
CP0452143
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-p-tolylacrylate
Show/Hide
|
C16H17N3O4
|
1
|
| 1 |
IC50 = 9650 nM
|
|
|
|
CP0436088
|
1-benzyl-N-{5-ethyl-6-[(ethylamino)methyl]pyrrolo[1,2-a][1,2,4]triazin-4-yl}-1H-indazol-5-amine
Show/Hide
|
C25H27N7
|
1
|
| 1 |
IC50 = 9700 nM
|
|
|
|
CP0879040
|
5-Trifluoromethyl-2'-(3-trifluoromethyl-phenoxymethyl)-biphenyl-3-sulfonic acid [2-(3-fluoro-phenyl)-ethyl]-amide
Show/Hide
|
C29H22F7NO3S
|
1
|
| 1 |
IC50 = 9710 nM
|
|
|
|
CP0492788
|
4-(Bis(2-chloroethyl)amino)-N-(2-bromophenyl)benzamide
Show/Hide
|
C17H17BrCl2N2O
|
1
|
| 1 |
IC50 = 9950 nM
|
|
|
|
CP0847128
|
2-(3,5-Bis(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13Cl2N3OS
|
1
|
| 1 |
IC50 = 9960 nM
|
|
|
|
CP0467438
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-isopropylphenyl)acrylate
Show/Hide
|
C18H21N3O4
|
1
|
| 1 |
IC50 = 9970 nM
|
|
|
|
CP0384971
|
4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-phenylbenzamide
Show/Hide
|
C34H29N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0384977
|
3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-methylbenzamide
Show/Hide
|
C29H27N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0406566
|
N-[3-[4-[4-(1-acetylpiperidin-4-yl)oxy-3-methylanilino]quinazolin-6-yl]prop-2-ynyl]-2-methoxyacetamide
Show/Hide
|
C28H31N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435597
|
2-methoxy-N-(3-(4-(3-methyl-4-(piperidin-4-yloxy)phenylamino)quinazolin-6-yl)prop-2-ynyl)acetamide
Show/Hide
|
C26H29N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435601
|
N-tert-butyl-4-[4-[[6-[3-[(2-methoxyacetyl)amino]prop-1-ynyl]quinazolin-4-yl]amino]-2-methylphenoxy]benzamide
Show/Hide
|
C32H33N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0435602
|
4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N-methylbenzamide
Show/Hide
|
C29H27N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0439663
|
2-methoxy-N-(3-(4-(3-methyl-4-(1-methylpiperidin-4-yloxy)phenylamino)quinazolin-6-yl)prop-2-ynyl)acetamide
Show/Hide
|
C27H31N5O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0439665
|
4-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N,N-dimethylbenzamide
Show/Hide
|
C30H29N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0496929
|
3-(4-(6-(3-(2-methoxyacetamido)prop-1-ynyl)quinazolin-4-ylamino)-2-methylphenoxy)-N,N-dimethylbenzamide
Show/Hide
|
C30H29N5O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0514243
|
2-methoxy-N-(3-(4-(4-(1-(2-methoxyacetyl)piperidin-4-yloxy)-3-methylphenylamino)quinazolin-6-yl)prop-2-ynyl)acetamide
Show/Hide
|
C29H33N5O5
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0924341
|
2-(2-(3-Bromobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8BrN3OS
|
1
|
| 1 |
IC50 = 10260 nM
|
|
|
|
CP0890834
|
2-(3-(4-Fluorophenyl)-5-(p-tolyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3OS
|
1
|
| 1 |
IC50 = 10260 nM
|
|
|
|
CP0847121
|
2-(3-(4-Chlorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16ClN3O2S
|
1
|
| 1 |
IC50 = 10340 nM
|
|
|
|
CP0879057
|
N-[2-(3-Fluoro-phenyl)-ethyl]-3-thianthren-1-yl-5-trifluoromethyl-benzenesulfonamide
Show/Hide
|
C27H19F4NO2S3
|
1
|
| 1 |
IC50 = 10400 nM
|
|
|
|
CP0885545
|
2-(3,5-bis(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C20H19N3O3S
|
1
|
| 1 |
IC50 = 10480 nM
|
|
|
|
CP0935261
|
2-(3-(4-Fluorophenyl)-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H14FN3OS
|
1
|
| 1 |
IC50 = 10530 nM
|
|
|
|
CP0514506
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethylcinnamate
Show/Hide
|
C15H15N3O4
|
1
|
| 1 |
IC50 = 10780 nM
|
|
|
|
CP0520466
|
1-(3,5-Dibromo-2-hydroxybenzyl)-1-(4-fluorobenzyl)-3-phenylurea
Show/Hide
|
C21H17Br2FN2O2
|
1
|
| 1 |
IC50 = 12420 nM
|
|
|
|
CP0853521
|
2-(3-(4-Fluorophenyl)-5-(4-methoxyphenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C19H16FN3O2S
|
1
|
| 1 |
IC50 = 12430 nM
|
|
|
|
CP0507694
|
4-(Bis(2-chloroethyl)amino)-N-(2-chlorophenyl)benzamide
Show/Hide
|
C17H17Cl3N2O
|
1
|
| 1 |
IC50 = 12870 nM
|
|
|
|
CP0847126
|
2-(5-(4-Chlorophenyl)-3-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13ClFN3OS
|
1
|
| 1 |
IC50 = 13160 nM
|
|
|
|
CP0473224
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(4-methoxyphenyl)acrylate
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 14320 nM
|
|
|
|
CP0913243
|
2-(2-(3-Chlorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8ClN3OS
|
1
|
| 1 |
IC50 = 14340 nM
|
|
|
|
CP0460316
|
2-amino-4-(7-methyltetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C25H20N8O
|
1
|
| 1 |
IC50 = 14800 nM
|
|
|
|
CP0492787
|
4-(Bis(2-chloroethyl)amino)-N-(2-fluorophenyl)benzamide
Show/Hide
|
C17H17Cl2FN2O
|
1
|
| 1 |
IC50 = 15390 nM
|
|
|
|
CP0430869
|
1-(4-Fluorobenzyl)-1-(2-hydroxy-5-methylbenzyl)-3-phenylthiourea
Show/Hide
|
C22H21FN2OS
|
1
|
| 1 |
IC50 = 15660 nM
|
|
|
|
CP0522057
|
1-(2-Hydroxy-3,5-dimethylbenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
IC50 = 16120 nM
|
|
|
|
CP0847127
|
2-(3-(4-Chlorophenyl)-5-(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13ClFN3OS
|
1
|
| 1 |
IC50 = 16420 nM
|
|
|
|
CP0427702
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-fluorophenyl)acrylate
Show/Hide
|
C15H14FN3O4
|
1
|
| 1 |
IC50 = 16750 nM
|
|
|
|
CP0879039
|
5-Trifluoromethyl-4'-(3-trifluoromethyl-phenoxymethyl)-biphenyl-3-sulfonic acid [2-(3-fluoro-phenyl)-ethyl]-amide
Show/Hide
|
C29H22F7NO3S
|
1
|
| 1 |
IC50 = 18000 nM
|
|
|
|
CP0878668
|
2-(3,5-Bis(4-fluorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)thiazol-4(5H)-one
Show/Hide
|
C18H13F2N3OS
|
1
|
| 1 |
IC50 = 18120 nM
|
|
|
|
CP0373847
|
1-(2-Hydroxy-5-methylbenzyl)-1-(4-hydroxybenzyl)-3-phenylurea
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
IC50 = 18430 nM
|
|
|
|
CP0400315
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-methoxyphenyl)acrylate
Show/Hide
|
C16H17N3O5
|
1
|
| 1 |
IC50 = 18820 nM
|
|
|
|
CP0434965
|
N-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]methanesulfonamide
Show/Hide
|
C26H18ClF3N4O3S2
|
1
|
| 1 |
IC50 = 19200 nM
|
|
|
|
CP0509091
|
2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile
Show/Hide
|
C24H17ClN8O
|
1
|
| 1 |
IC50 = 19300 nM
|
|
|
|
CP0428883
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(3-nitrophenyl)acrylate
Show/Hide
|
C15H14N4O6
|
1
|
| 1 |
IC50 = 19340 nM
|
|
|
|
CP0859408
|
2-(2-(3-Fluorobenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H8FN3OS
|
1
|
| 1 |
IC50 = 21750 nM
|
|
|
|
CP0494510
|
ethyl 2-amino-4-(7-chlorotetrazolo[1,5-a]quinolin-4-yl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carboxylate
Show/Hide
|
C26H22ClN7O3
|
1
|
| 1 |
IC50 = 22700 nM
|
|
|
|
CP0426999
|
4-(Bis(2-chloroethyl)amino)-N-methyl-N-phenylbenzamide
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 22750 nM
|
|
|
|
CP0139001
|
N-(4-fluorophenyl)-1-methyl-3-[[methyl-[2-(4-phenylphenyl)ethyl]amino]methyl]indole-5-carboxamide
Show/Hide
|
C32H30FN3O
|
1
|
| 1 |
IC50 = 24000 nM
|
|
|
|
CP0483695
|
ethyl 5-benzyl-4-[(1-benzylindazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazine-6-carboxylate
Show/Hide
|
C30H26N6O2
|
1
|
| 1 |
IC50 > 25000 nM
|
|
|
|
CP0851720
|
4'-[4-(2-Methoxy-ethyl)-phenoxymethyl]-5-trifluoromethyl-biphenyl-3-sulfonic acid [2-(3-fluoro-phenyl)-ethyl]-amide
Show/Hide
|
C31H29F4NO4S
|
1
|
| 1 |
IC50 = 25400 nM
|
|
|
|
CP0492790
|
N-benzyl-4-[bis(2-chloroethyl)amino]benzamide
Show/Hide
|
C18H20Cl2N2O
|
1
|
| 1 |
IC50 = 25870 nM
|
|
|
|
CP0426998
|
4-(Bis(2-chloroethyl)amino)-N-(4-nitrophenyl)benzamide
Show/Hide
|
C17H17Cl2N3O3
|
1
|
| 1 |
IC50 = 27190 nM
|
|
|
|
CP0885036
|
2-(2-(3-Hydroxybenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C10H9N3O2S
|
1
|
| 1 |
IC50 = 27830 nM
|
|
|
|
CP0861440
|
N-(3-(Benzyloxy)phenyl)-(6-morpholinosulfonyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
|
C28H26N4O4S
|
1
|
| 1 |
IC50 = 28300 nM
|
|
|
|
CP0498687
|
4-(Bis(2-chloroethyl)amino)-N-butylbenzamide
Show/Hide
|
C15H22Cl2N2O
|
1
|
| 1 |
IC50 = 30060 nM
|
|
|
|
CP0913244
|
2-(2-Cyclooctylidenehydrazono)thiazolidin-4-one
Show/Hide
|
C11H17N3OS
|
1
|
| 1 |
IC50 = 31000 nM
|
|
|
|
CP0914245
|
3-(2,2'-bithiophen-5-yl)-N-(3-fluorophenethyl)-5-(trifluoromethyl)benzenesulfonamide
Show/Hide
|
C23H17F4NO2S3
|
1
|
| 1 |
IC50 = 31500 nM
|
|
|
|
CP0905450
|
2-(2-(3-Methylbenzylidene)hydrazinyl)thiazol-4(5H)-one
Show/Hide
|
C11H11N3OS
|
1
|
| 1 |
IC50 = 31780 nM
|
|
|
|
CP0407065
|
1-Butyl-1-(5-chloro-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C18H21ClN2OS
|
1
|
| 1 |
IC50 = 32540 nM
|
|
|
|
CP0009041
|
5-propan-2-yl-7,8-dihydro-6H-indeno[1,2-b]indole-9,10-dione
Show/Hide
|
C18H17NO2
|
1
|
| 1 |
IC50 > 35000 nM
|
|
|
|
CP0372727
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-chlorophenyl)acrylate
Show/Hide
|
C15H14ClN3O4
|
1
|
| 1 |
IC50 = 36450 nM
|
|
|
|
CP0481820
|
1-[4-[4-[3-chloro-4-[3-(trifluoromethyl)phenoxy]anilino]thieno[2,3-d]pyrimidin-6-yl]phenyl]-3-cyclopropylurea
Show/Hide
|
C29H21ClF3N5O2S
|
1
|
| 1 |
IC50 = 37100 nM
|
|
|
|
CP0517623
|
(E)-2((E)-(3-nitrobenzylidene)hydrazono)thiazolidin-4-one (8)
Show/Hide
|
C10H8N4O3S
|
1
|
| 1 |
IC50 = 37640 nM
|
|
|
|
CP0489637
|
1-(4-Fluorobenzyl)-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylthiourea
Show/Hide
|
C23H23FN2OS
|
1
|
| 1 |
IC50 = 37820 nM
|
|
|
|
CP0447437
|
1-(4-Fluorobenzyl)-1-(2-hydroxy-5-methylbenzyl)-3-phenylurea
Show/Hide
|
C22H21FN2O2
|
1
|
| 1 |
IC50 = 38230 nM
|
|
|
|
CP0491208
|
1-(5-Bromo-2-hydroxybenzyl)-1-butyl-3-phenylthiourea
Show/Hide
|
C18H21BrN2OS
|
1
|
| 1 |
IC50 = 39510 nM
|
|
|
|
CP0421854
|
4-(Bis(2-chloroethyl)amino)-N,N-dipropylbenzamide
Show/Hide
|
C17H26Cl2N2O
|
1
|
| 1 |
IC50 = 39640 nM
|
|
|
|
CP0429967
|
1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
|
C18H20Cl2N2OS
|
1
|
| 1 |
IC50 = 39780 nM
|
|
|
|
CP0401884
|
(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-nitrophenyl)acrylate
Show/Hide
|
C15H14N4O6
|
1
|
| 1 |
IC50 = 40000 nM
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CP0400314
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-fluorophenyl)acrylate
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C15H14FN3O4
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1
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| 1 |
IC50 = 41260 nM
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CP0498689
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4-(Bis(2-chloroethyl)amino)-N,N-dibutylbenzamide
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C19H30Cl2N2O
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1
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| 1 |
IC50 = 44510 nM
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CP0514950
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl3-(2-bromophenyl)acrylate
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C15H14BrN3O4
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1
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| 1 |
IC50 = 44850 nM
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CP0859409
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2-(2-(3-Methoxybenzylidene)hydrazinyl)thiazol-4(5H)-one
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C11H11N3O2S
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1
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| 1 |
IC50 = 45510 nM
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CP0427001
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4-(Bis(2-chloroethyl)amino)-N-tert-butylbenzamide
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C15H22Cl2N2O
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1
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| 1 |
IC50 = 46100 nM
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CP0913245
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2-(2-Cycloheptylidenehydrazono)thiazolidin-4-one
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C10H15N3OS
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1
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| 1 |
IC50 = 47000 nM
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CP0383876
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4-(Bis(2-chloroethyl)amino)-N-cyclopentylbenzamide
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C16H22Cl2N2O
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1
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| 1 |
IC50 = 48350 nM
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CP0885037
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2-(2-Cyclobutylidenehydrazinyl)thiazol-4(5H)-one
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C7H9N3OS
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1
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| 1 |
IC50 > 50000 nM
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CP0924340
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2-(2-Cyclohexylidenehydrazono)thiazolidin-4-one
Show/Hide
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C9H13N3OS
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1
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| 1 |
IC50 > 50000 nM
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CP0926266
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2-(2-Cyclopentylidenehydrazono)thiazolidin-4-one
Show/Hide
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C8H11N3OS
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1
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| 1 |
IC50 > 50000 nM
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CP0401403
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1-Butyl-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylurea
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C18H20Br2N2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0406246
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1-(5-Bromo-2-hydroxybenzyl)-1-butyl-3-phenylurea
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C18H21BrN2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0429956
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1-Butyl-1-(2-hydroxy-5-methylbenzyl)-3-phenylurea
Show/Hide
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C19H24N2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0430867
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1-Butyl-1-(3,5-dichloro-2-hydroxybenzyl)-3-phenylturea
Show/Hide
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C18H20Cl2N2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0439054
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1-Butyl-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylthiourea
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C23H24N2OS
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1
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| 1 |
IC50 > 50000 nM
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CP0440139
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1-(4-fluorobenzyl)-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylurea
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C23H23FN2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0440209
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1-Butyl-1-(2-hydroxy-5-methylbenzyl)-3-phenylthiourea
Show/Hide
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C19H24N2OS
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1
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| 1 |
IC50 > 50000 nM
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CP0489669
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1-Butyl-1-(5-chloro-2-hydroxybenzyl)-3-phenylurea
Show/Hide
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C18H21ClN2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0491205
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1-Butyl-1-(2-hydroxy-3,5-dimethylbenzyl)-3-phenylurea
Show/Hide
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C20H26N2O2
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1
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| 1 |
IC50 > 50000 nM
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CP0491209
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1-Butyl-1-(3,5-dibromo-2-hydroxybenzyl)-3-phenylthiourea
Show/Hide
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C18H20Br2N2OS
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1
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| 1 |
IC50 > 50000 nM
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CP0492789
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4-(Bis(2-chloroethyl)amino)-N-(3-morpholinopropyl)benzamide
Show/Hide
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C18H27Cl2N3O2
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1
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| 1 |
IC50 > 50000 nM
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CP0517599
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4-(Bis(2-chloroethyl)amino)-N-dodecylbenzamide
Show/Hide
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C23H38Cl2N2O
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1
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| 1 |
IC50 > 50000 nM
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CP0427704
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(E)-2-(2-Methyl-5-nitro-1H-imidazol-1-yl)ethyl 3-(2-methoxyphenyl)acrylate
Show/Hide
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C16H17N3O5
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1
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| 1 |
IC50 > 50000 nM
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CP0953333
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N-(3-Ethoxyphenyl)-(6-morpholinosulfonyl)-9H-pyrido[2,3-b]indol-4-amine
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C23H24N4O4S
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1
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| 1 |
IC50 = 54800 nM
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CP0892089
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6-bromo-N-(3-methoxyphenyl)-9H-pyrido[2,3-b]indol-4-amine
Show/Hide
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C18H14BrN3O
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1
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| 1 |
IC50 = 91200 nM
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CP0118159
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N-(1H-indazol-5-yl)-5-methylpyrrolo[2,1-f][1,2,4]triazin-4-amine
Show/Hide
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C14H12N6
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1
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| 1 |
IC50 > 1000 nM
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CP0253829
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(3-Chloro-4-fluoro-phenyl)-(5-methyl-pyrrolo[2,1-f][1,2,4]triazin-4-yl)-amine
Show/Hide
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C13H10ClFN4
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1
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| 1 |
IC50 > 1000 nM
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CP0380018
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(E)-4-(4-methylpiperazin-1-yl)-N-[4-[4-(pyridin-2-ylmethyl)anilino]pyrido[3,4-d]pyrimidin-6-yl]but-2-enamide
Show/Hide
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C28H30N8O
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1
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| 1 |
IC50 > 1000 nM
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CP0431360
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(E)-N-[7-ethoxy-4-[4-(pyridin-2-ylmethoxy)anilino]quinazolin-6-yl]-4-(4-methylpiperazin-1-yl)but-2-enamide
Show/Hide
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C31H35N7O3
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1
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| 1 |
IC50 > 1000 nM
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