Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-N-[7-hydroxy-4-(3-methyl-4-pyrazolo[1,5-a]pyrimidin-6-yloxyanilino)quinazolin-6-yl]-3-[(2R)-1-methylpyrrolidin-2-yl]prop-2-enamide
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 PubChem ID
CID: 168283966
Canonical SMILES
CN1CCC[C@@H]1\C=C\C(=O)Nc1cc2c(Nc3ccc(Oc4cnc5ccnn5c4)c(C)c3)ncnc2cc1O
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Compound Formula C29H28N8O3
Compound Structure
Protein Name
 Protein Info 
Receptor tyrosine-protein kinase erbB-2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P04626
Gene Name
ERBB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 2.41 nM
   TI
   LI
   LO
   TS