Brief Information of the Cell Line and Protein
Cell Line ID: CL000012 , Sf21
 Cell Line Info 
Synonyms
SF21
Sf-21
SF-21
IPLB-SF-21-AE
IPLB-Sf21-AE
IPLB-SF21-AE
IPLB-SF 21AE
IPLB-Sf21AE
IPLB-SF21AE
IPLB-SF-21
IPLB-Sf-21
IPLB-SF 21
IPLB-Sf21
IPLB-SF21
Category Spontaneously immortalized cell line
Organism
Spodoptera frugiperda (Fall armyworm)
Cellosaurus ID
CVCL_0518
Protein ID: PT01381 , Serine/threonine-protein kinase B-raf
 Protein Info 
Gene Name BRAF
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P15056
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000012
 Cell Line Info 
 Protein ID: PT01381
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0110489
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-3-(trifluoromethyl)benzamide
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C24H19F3N4O2
  1
1
IC50 = 0.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0408514
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-3-tert-butylbenzamide
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C27H28N4O2
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0429721
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-3-chlorobenzamide
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C23H19ClN4O2
  1
1
IC50 = 0.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0086011
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-4-(trifluoromethyl)pyridine-2-carboxamide
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C23H18F3N5O2
  1
1
IC50 = 0.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548229
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-3-[(2S)-2,4-dimethylpiperazin-1-yl]-5-(trifluoromethyl)benzamide
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C30H31F3N6O2
  1
1
IC50 = 3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148909
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)benzamide
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C30H31F3N6O2
  1
1
IC50 = 5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0548228
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]-6-(trifluoromethyl)pyridine-2-carboxamide
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C23H18F3N5O2
  1
1
IC50 = 6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148908
 Compound Info 
N-[3-(2-acetamidoimidazo[1,2-a]pyridin-6-yl)-4-methylphenyl]benzamide
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C23H20N4O2
  1
1
IC50 = 61 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS