| Compound ID |
Compound Name |
Compound Formula |
|
CP0447669
|
Carperitide
Show/Hide
|
C127H203N45O39S3
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0548773
|
(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(4R,10S,16R,19S,22S,28S,31S,34S,37S,40S,49S,52R)-52-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-19-(3-amino-3-oxopropyl)-49-benzyl-28,37-bis[(2S)-butan-2-yl]-31,40-bis(3-carbamimidamidopropyl)-34-(carboxymethyl)-16-(hydroxymethyl)-22-methyl-10-(2-methylpropyl)-6,9,12,15,18,21,24,27,30,33,36,39,42,45,48,51-hexadecaoxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50-hexadecazacyclotripentacontane-4-carbonyl]amino]-4-oxobutanoyl]amino]-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(4-hydroxyphenyl)propanoic acid
Show/Hide
|
C128H205N45O39S2
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0406660
|
1-[4-(2-amino-4-butyl-5-oxo-4H-imidazol-3-yl)-6-[4-[[4-(2-amino-4-butyl-5-oxo-4H-imidazol-3-yl)-6-carbamimidamido-1,3,5-triazin-2-yl]amino]anilino]-1,3,5-triazin-2-yl]guanidine;2,2,2-trifluoroacetic acid
Show/Hide
|
C32H40F6N20O6
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0548775
|
1-[4-[[6-(3-fluorophenyl)-2-(propan-2-ylamino)pyrido[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
Show/Hide
|
C28H38FN7O2
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0532093
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]pyrido[2,3-d]pyrimidin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
Show/Hide
|
C28H38FN7O3
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0545249
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
Show/Hide
|
C29H39FN6O3
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0482244
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-(1-hydroxy-2-methylpropan-2-yl)urea
Show/Hide
|
C28H37FN6O3
|
1
|
| 1 |
EC50 = 66 nM
|
|
|
|
CP0545248
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C27H35FN6O2
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0558910
|
2-[4-[[4-[[4-(diaminomethylideneamino)-6-[2-imino-5-(2-methylpropyl)-4-oxoimidazolidin-1-yl]-1,3,5-triazin-2-yl]amino]cyclohexyl]amino]-6-[2-imino-5-(2-methylpropyl)-4-oxoimidazolidin-1-yl]-1,3,5-triazin-2-yl]guanidine;2,2,2-trifluoroacetic acid
Show/Hide
|
C36H48F12N20O10
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0482243
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-[1-(hydroxymethyl)cyclopentyl]urea
Show/Hide
|
C30H39FN6O3
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0482245
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]pyrido[3,4-d]pyrimidin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
Show/Hide
|
C28H38FN7O3
|
1
|
| 1 |
EC50 = 130 nM
|
|
|
|
CP0427294
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-methoxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C28H37FN6O2
|
1
|
| 1 |
EC50 = 160 nM
|
|
|
|
CP0547323
|
1-cyclopropyl-3-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]urea
Show/Hide
|
C27H33FN6O2
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0417376
|
CHEMBL4210169
Show/Hide
|
C28H35FN6O2
|
1
|
| 1 |
EC50 = 270 nM
|
|
|
|
CP0417373
|
1-[4-[[6-(3-fluorophenyl)-2-(propan-2-ylamino)quinazolin-4-yl]amino]cyclohexyl]-3-[(2R)-1-hydroxy-3-methylbutan-2-yl]urea
Show/Hide
|
C29H39FN6O2
|
1
|
| 1 |
EC50 = 290 nM
|
|
|
|
CP0417374
|
CHEMBL4218179
Show/Hide
|
C29H39FN6O3
|
1
|
| 1 |
EC50 = 330 nM
|
|
|
|
CP0495340
|
1-[4-[[6-(3-fluorophenyl)-2-(propan-2-ylamino)quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C27H35FN6O
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0495338
|
CHEMBL4209251
Show/Hide
|
C27H35FN6O2
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0417370
|
1-[4-[[6-(3-fluorophenyl)-2-(2-methoxyethylamino)quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C27H35FN6O2
|
1
|
| 1 |
EC50 = 610 nM
|
|
|
|
CP0389271
|
N-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-hydroxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]-3-hydroxycyclobutane-1-carboxamide
Show/Hide
|
C28H34FN5O3
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0495339
|
CHEMBL4204379
Show/Hide
|
C27H33FN6O3
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0513833
|
1-[4-[[6-(3-fluorophenyl)-2-[[(2R)-1-methoxypropan-2-yl]amino]pyrido[3,2-d]pyrimidin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C27H36FN7O2
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0396429
|
1-cyclopropyl-3-[4-[[6-(3-fluorophenyl)-2-[[(2S)-1-methoxypropan-2-yl]amino]quinazolin-4-yl]amino]cyclohexyl]urea
Show/Hide
|
C28H35FN6O2
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0495341
|
3-hydroxy-N-[4-[[2-[[(2R)-1-hydroxypropan-2-yl]amino]-6-phenylquinazolin-4-yl]amino]cyclohexyl]cyclobutane-1-carboxamide
Show/Hide
|
C28H35N5O3
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0548774
|
N-[4-[[2-[[(2R)-1-hydroxypropan-2-yl]amino]-6-phenylquinazolin-4-yl]amino]cyclohexyl]-3-(propan-2-ylamino)cyclobutane-1-carboxamide
Show/Hide
|
C31H42N6O2
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0389270
|
1-[4-[[6-(3-fluorophenyl)-2-[2-hydroxyethyl(methyl)amino]quinazolin-4-yl]amino]cyclohexyl]-3-propan-2-ylurea
Show/Hide
|
C27H35FN6O2
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0417375
|
CHEMBL4214562
Show/Hide
|
C28H37FN6O
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0482246
|
CHEMBL4206328
Show/Hide
|
C30H40FN7O2
|
1
|
| 1 |
EC50 = 3200 nM
|
|
|
