Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT06423 , Beta-3 adrenergic receptor
 Protein Info 
Gene Name ADRB3
Organism Macaca mulatta, Rhesus macaque
Protein Classification Membrane receptor
Uniprot ID Q28524
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT06423
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0135429
 Compound Info 
(4R)-2-amino-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-5,6-dihydro-4H-cyclopenta[d][1,3]thiazole-4-carboxamide
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C25H28N4O2S
  1
1
EC50 = 0.06 nM
 Bioactivity Info 
   TI
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CP0156740
 Compound Info 
(R)-N-(4-(2-(2-hydroxy-2-(pyridin-3-yl)ethylamino)ethyl)phenyl)-4-(4-(4-(trifluoromethyl)phenyl)thiazol-2-yl)benzenesulfonamide
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C31H27F3N4O3S2
  2
1
EC50 = 0.43 nM
 Bioactivity Info 
   TI
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2
EC50 = 17 nM
 Bioactivity Info 
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CP0105650
 Compound Info 
KRP-114V
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C26H28N4O3
  2
1
EC50 = 0.57 nM
 Bioactivity Info 
   TI
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2
EC50 = 7.1 nM
 Bioactivity Info 
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CP0135426
 Compound Info 
(4R)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(pyridin-3-yl)methyl]pyrrolidin-2-yl]methyl]phenyl]-5,6-dihydro-4H-cyclopenta[d][1,3]thiazole-4-carboxamide
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C24H26N4O2S
  1
1
EC50 = 2 nM
 Bioactivity Info 
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CP0156745
 Compound Info 
(2S)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-2-(6-oxopyridazin-1-yl)propanamide
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C25H28N4O3
  2
1
EC50 = 2.5 nM
 Bioactivity Info 
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2
EC50 = 12 nM
 Bioactivity Info 
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CP0105652
 Compound Info 
N-[4-[[(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl]methyl]phenyl]-2-(6-oxopyridazin-1-yl)acetamide
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C24H26N4O3
  1
1
EC50 = 3.5 nM
 Bioactivity Info 
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CP0105651
 Compound Info 
(6S)-N-[4-[[(2S,5R)-5-[(R)-hydroxy(pyridin-3-yl)methyl]pyrrolidin-2-yl]methyl]phenyl]-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-6-carboxamide
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C24H27N5O2
  1
1
EC50 = 4.7 nM
 Bioactivity Info 
   TI
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