(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-methyl-2-(2-phenylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-methylpurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)-4-methoxybenzamide

N-(2-phenylimidazo[1,2-a]pyrazin-8-yl)benzamide

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)pyridine-3-carboxamide

N-benzoyl-N-(2-phenylimidazo[1,2-a]pyrazin-8-yl)benzamide

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)benzamide

(1S,2R,3S,4R,5S)-4-[2-azido-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(5-bromothiophen-2-yl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-azido-6-(ethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-azido-6-(cyclobutylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-azido-6-(2-phenylethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[2-iodo-6-(2-phenylethylamino)purin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(2-chlorophenyl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-(methylamino)-2-(4-phenyltriazol-1-yl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(furan-2-yl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(3,4-difluorophenyl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-azido-6-[(3-chlorophenyl)methylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-6-(ethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[6-(ethylamino)-2-iodopurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(1-benzofuran-2-yl)triazol-1-yl]-6-(methylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[6-(cyclobutylamino)-2-iodopurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[5-[2-(5-chlorothiophen-2-yl)ethynyl]-7-(ethylamino)imidazo[4,5-b]pyridin-3-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-(methylamino)-2-(4-pyridin-2-yltriazol-1-yl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-(methylamino)-2-[4-(1-methylpyrazol-4-yl)triazol-1-yl]purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-(methylamino)-2-(4-pyrazin-2-yltriazol-1-yl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-(methylamino)-2-(4-pyrimidin-2-yltriazol-1-yl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-6-(2-phenylethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[4-(5-chlorothiophen-2-yl)triazol-1-yl]-6-(cyclobutylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[6-[(3-chlorophenyl)methylamino]-2-[4-(5-chlorothiophen-2-yl)triazol-1-yl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-(dimethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

N2-benzyl-8-(furan-2-yl)-9-propyl-9H-purine-2,6-diamine

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)-4-fluorobenzamide

8-(Furan-2-yl)-N2-phenethyl-9-propyl-9H-purine-2,6-diamine

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)furan-2-carboxamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[6-[(Z)-2-hydroxy-2-phenylethenyl]-2-(2-phenylethynyl)purin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[2-(4-tert-butylphenyl)ethynyl]-6-[(Z)-2-(4-tert-butylphenyl)-2-hydroxyethenyl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-[2-(3,4-difluorophenyl)ethynyl]-6-methylpurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

N-[(3-chlorophenyl)methyl]-2-[2-(3,4-difluorophenyl)ethynyl]-7H-purin-6-amine

N-[2-(4-methoxyphenyl)imidazo[1,2-a]pyrazin-8-yl]benzamide

(1S,2R,3S,4R,5S)-4-[2-[2-(3,4-difluorophenyl)ethynyl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

4-chloro-N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)benzamide

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(1R)-1-cyclopropylpropyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

4-methoxy-N-(2-phenylimidazo[1,2-a]pyrazin-8-yl)benzamide

2-chloro-N-[(3-chlorophenyl)methyl]-7H-purin-6-amine

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)thiophene-2-carboxamide

N-(2,6-diphenylimidazo[1,2-a]pyrazin-8-yl)-4-methylbenzamide

ethyl (1S,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate

2,2-diphenyl-N-(2-phenylimidazo[1,2-a]pyrazin-8-yl)acetamide

8-(Furan-2-yl)-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine

(1S,2R,3S,4R,5S)-4-[2-[2-(4-tert-butylphenyl)ethynyl]-6-methylpurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

N-[2-(4-methoxyphenyl)-6-phenylimidazo[1,2-a]pyrazin-8-yl]benzamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[6-methyl-2-(2-pyrazin-2-ylethynyl)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

N-benzyl-8-(furan-2-yl)-9-propyl-9H-purin-6-amine

(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol

propyl (1S,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate

(1S,2R,3S,4R,5S)-4-[2-[2-(2-chlorophenyl)ethynyl]-6-[(Z)-2-(2-chlorophenyl)-2-hydroxyethenyl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

2-phenyl-N-(2-phenylimidazo[1,2-a]pyrazin-8-yl)acetamide

(1S,2R,3S,4R,5S)-2,3-dihydroxy-N-methyl-4-[2-(methylamino)purin-9-yl]bicyclo[3.1.0]hexane-1-carboxamide

N2-Benzyl-8-bromo-9-propyl-9H-purine-2,6-diamine

(1S,2R,3S,4R,5S)-4-[2-[2-(5-chlorothiophen-2-yl)ethynyl]-6-methoxypurin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

3-(4-Bromothiophen-2-yl)-8-hydroxycoumarin

methyl (1S,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylate

8-(furan-2-yl)-9-propylpurin-6-amine

8-(Furan-2-yl)-N-phenethyl-9-propyl-9H-purin-6-amine

8-(Furan-2-yl)-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(dimethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid

(1S,2R,3S,4R,5S)-4-[2-chloro-6-[(Z)-2-hydroxy-2-phenylethenyl]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

8-Bromo-N2-phenethyl-9-propyl-9H-purine-2,6-diamine

(1R,2R,3S,4R,5S)-4-[2-chloro-6-(pentan-3-ylamino)purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(1R)-1-cyclopropyl-2-methylpropyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

8-Hydroxy-3-(thiophen-2-yl)coumarin

(1S,2R,3S,4R,5S)-2,3-dihydroxy-4-[2-[(Z)-2-hydroxy-2-pyrazin-2-ylethenyl]purin-9-yl]-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(dimethylamino)purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

(1S,2R,3S,4R,5S)-N-(2-acetamidoethyl)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxamide

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(1S)-1-cyclopropylpropyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

8-Acetoxy-3-(thiophen-3-yl)coumarin

8-Bromo-N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine

(1S,2R,3S,4R,5S)-N-(3-acetamidopropyl)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxamide

(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dimethylamino)purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

8-Bromo-N-phenethyl-9-propyl-9H-purin-6-amine

8-Acetoxy-3-(thiophen-2-yl)coumarin

8-Hydroxy-3-(thiophen-3-yl)coumarin

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(S)-cyclobutyl(cyclopropyl)methyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

3-(4-bromothiophen-2-yl)-7,8-dihydroxy-2H-chromen-2-one

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(1S)-1-cyclopropyl-2-methylpropyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

(1R,2R,3S,4R,5S)-4-[2-chloro-6-[[(R)-cyclobutyl(cyclopropyl)methyl]amino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol

2-oxo-3-(thiophen-3-yl)-2H-chromene-7,8-diyl diacetate

8-Acetoxy-3-(4-bromothiophen-2-yl)coumarin

7,8-dihydroxy-3-(thiophen-2-yl)-2H-chromen-2-one

(1'R,2'R,3'S,4'R,5'S)-4'-[2-Chloro-6-(3-chlorobenzylamino)-purine]-2',3'-O-dihydroxybicyclo-[3.1.0]hexane

7,8-dihydroxy-3-(thiophen-3-yl)-2H-chromen-2-one

N2-benzyl-9-propyl-9H-purine-2,6-diamine

N2-phenethyl-9-propyl-9H-purine-2,6-diamine

(1S,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxylic acid

N-benzyl-8-bromo-9-propyl-9H-purin-6-amine

8-Bromo-N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine

N2-(3-phenylpropyl)-9-propyl-9H-purine-2,6-diamine

N-phenethyl-9-propyl-9H-purin-6-amine

7,8-Diacetoxy-3-(thiophen-2-yl)coumarin

N-benzyl-9-propyl-9H-purin-6-amine

N-(3-phenylpropyl)-9-propyl-9H-purin-6-amine

1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione

9-Propyl-9H-adenine

8-Bromo-9-propyl-9H-adenine

3-(4-bromothiophen-2-yl)-2-oxo-2H-chromene-7,8-diyl diacetate