| Compound ID |
Compound Name |
Compound Formula |
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CP0924357
|
(2S)-5-[2-[2-[2-[2-[2-[2-[[(1S)-4-amino-1-[[(1S)-1-[(2S)-2-[[(1S)-1-[[(1S)-1-[[(1S)-2-[[(1S)-2-[[(1S)-5-amino-1-[[2-[(2S)-2-[[(1S)-1-[(2S)-2-[[(1S)-1-carboxy-2-phenyl-ethyl]carbamoyl]pyrrolidine-1-carbonyl]-3-methylsulfanyl-propyl]carbamoyl]pyrrolidin-1-yl]-2-oxo-ethyl]carbamoyl]pentyl]amino]-1-(1H-imidazol-4-ylmethyl)-2-oxo-ethyl]amino]-1-(hydroxymethyl)-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-4-guanidino-butyl]carbamoyl]pyrrolidine-1-carbonyl]-4-guanidino-butyl]carbamoyl]-4-oxo-butyl]amino]-2-oxo-ethoxy]ethoxy]ethylamino]-2-oxo-ethoxy]ethoxy]ethylamino]-5-oxo-2-(tridecanoylamino)pentanoic acid
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C99H164N26O26S
|
1
|
| 1 |
EC50 = 0.23 nM
|
|
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CP0235875
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C69H108N22O16S
|
4
|
| 1 |
EC50 = 0.3 nM
|
|
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| 2 |
EC50 = 0.42 nM
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|
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| 3 |
EC50 = 2 nM
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|
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| 4 |
EC50 = 3.11 nM
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CP0564495
|
N-[(3S)-1-(cyclobutylamino)-5-[methyl(2-methylpropyl)amino]-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
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C30H42F3N5O2
|
2
|
| 1 |
EC50 = 0.35 nM
|
|
|
| 2 |
EC50 = 24 nM
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CP0153773
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2,5-diamino-5-oxopentanoyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
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C69H111N23O16S
|
1
|
| 1 |
EC50 = 0.87 nM
|
|
|
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CP0567571
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-oxo-5-piperidin-1-yl-1-(1,3-thiazol-2-ylamino)pentan-3-yl]pyrazole-3-carboxamide
Show/Hide
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C30H40N6O4S
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
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CP0414744
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H90N18O11
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
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CP0495176
|
(2R)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-6-aminohexanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H90N16O11
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
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CP0414741
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C53H92N20O12
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
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CP0564626
|
N-[(3S)-1-(cyclobutylamino)-5-[cyclohexyl(methyl)amino]-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C32H44F3N5O2
|
2
|
| 1 |
EC50 = 2 nM
|
|
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| 2 |
EC50 = 14 nM
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CP0414735
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-6-aminohexanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]hexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H89N15O11
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
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CP0564483
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C30H40F3N5O2
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
EC50 = 64 nM
|
|
|
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CP0414742
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H89N15O11
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
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CP0564494
|
N-[(3S)-1-(cyclobutylamino)-5-(3,3-difluoropiperidin-1-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C30H38F5N5O2
|
2
|
| 1 |
EC50 = 3.4 nM
|
|
|
| 2 |
EC50 = 11 nM
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|
|
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CP0564627
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N-[(2R)-4-(cyclobutylamino)-1-(3,3-difluoroazetidin-1-yl)-4-oxobutan-2-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C27H32F5N5O2
|
2
|
| 1 |
EC50 = 4 nM
|
|
|
| 2 |
EC50 = 67 nM
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CP0544915
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-[2-(1,1-difluoroethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C31H43F2N5O2
|
2
|
| 1 |
EC50 = 4.3 nM
|
|
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| 2 |
EC50 = 46 nM
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CP0481411
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C52H90N20O12S
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
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CP0550685
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C56H90N20O12
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
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CP0538572
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-[methyl(1,3-thiazol-2-yl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C31H42N6O4S
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
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CP0573728
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-fluoro-6-methoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C30H42FN5O3
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2
|
| 1 |
EC50 = 5.6 nM
|
|
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| 2 |
EC50 = 90 nM
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CP0551758
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-[(2S)-2-(trifluoromethyl)piperidin-1-yl]pentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C31H39F6N5O2
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2
|
| 1 |
EC50 = 6 nM
|
|
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| 2 |
EC50 = 31 nM
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CP0546874
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-cyclopropylphenyl)pyrazole-3-carboxamide
Show/Hide
|
C32H45N5O2
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2
|
| 1 |
EC50 = 6.4 nM
|
|
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| 2 |
EC50 = 49 nM
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CP0546508
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1-cyclopentyl-N-[(3S)-5-(3,3-difluoropiperidin-1-yl)-1-oxo-1-(2H-tetrazol-5-ylamino)pentan-3-yl]-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C27H32F5N9O2
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2
|
| 1 |
EC50 = 6.5 nM
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|
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| 2 |
EC50 = 24 nM
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CP0574566
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-ethylphenyl)pyrazole-3-carboxamide
Show/Hide
|
C31H45N5O2
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2
|
| 1 |
EC50 = 7 nM
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|
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| 2 |
EC50 = 44 nM
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CP0546407
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N-[(3S)-5-(azepan-1-yl)-1-(cyclobutylamino)-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C32H48ClN5O4
|
1
|
| 1 |
EC50 = 8 nM
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CP0414736
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]propanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C47H83N15O11
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1
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| 1 |
EC50 = 8.9 nM
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|
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CP0551630
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1-cyclopentyl-N-[(3S)-1-[(3,3-difluorocyclobutyl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C31H43F2N5O4
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1
|
| 1 |
EC50 = 9 nM
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CP0545129
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N-[(3S)-1-(cyclobutylamino)-5-(4-fluorophenyl)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C31H34F4N4O2
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2
|
| 1 |
EC50 = 15 nM
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| 2 |
EC50 = 103 nM
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CP0495175
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[2-[(2S)-2-[[(2S)-1-amino-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Show/Hide
|
C55H96N22O13S
|
1
|
| 1 |
EC50 = 19 nM
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CP0414738
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[2-[(2S)-2-[[(2S)-1-[(2S)-2-carbamoylpyrrolidin-1-yl]-4-methylsulfanyl-1-oxobutan-2-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Show/Hide
|
C60H103N23O14S
|
1
|
| 1 |
EC50 = 20 nM
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CP0532228
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methyl 2-[[(2S)-2-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]-4-phenylbutanoyl]amino]acetate
Show/Hide
|
C29H36N4O6
|
2
|
| 1 |
EC50 = 21 nM
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|
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| 2 |
EC50 = 3090 nM
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CP0572907
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N-[(3S)-1-(cyclobutylamino)-5-(4-methylpyrazol-1-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C29H35F3N6O2
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2
|
| 1 |
EC50 = 26 nM
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|
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| 2 |
EC50 = 54 nM
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CP0473007
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methyl 2-[[(2S)-2-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]-4-phenylbutanoyl]-methylamino]acetate
Show/Hide
|
C30H38N4O6
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2
|
| 1 |
EC50 = 27 nM
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|
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| 2 |
EC50 = 266 nM
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CP0573718
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N-[(3S)-1-(cyclobutylamino)-5-morpholin-4-yl-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C29H38F3N5O3
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2
|
| 1 |
EC50 = 28 nM
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| 2 |
EC50 = 69 nM
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CP0397355
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C48H88N18O11
|
1
|
| 1 |
EC50 = 31 nM
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CP0440864
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]hexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H88N14O11
|
1
|
| 1 |
EC50 = 33 nM
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CP0552576
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N-[(3S)-1-(cyclobutylamino)-5-(2,6-dimethylpiperidin-1-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C33H50ClN5O4
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1
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| 1 |
EC50 = 33 nM
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CP0434897
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-6-aminohexanoyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C53H88N16O11
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1
|
| 1 |
EC50 = 44 nM
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CP0487507
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N-[(3S)-5-cyclohexyl-1-(2-hydroxybutylamino)-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C31H48N4O5
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2
|
| 1 |
EC50 = 46 nM
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|
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| 2 |
EC50 = 118 nM
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CP0525837
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N-[(3S)-1-(cyclobutylamino)-5-cyclohexyl-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-propylpyrazole-3-carboxamide
Show/Hide
|
C30H44N4O4
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2
|
| 1 |
EC50 = 49 nM
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|
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| 2 |
EC50 = 107 nM
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CP0525839
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N-[(3S)-5-cyclohexyl-1-[[(2R)-2-hydroxybutyl]amino]-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C31H48N4O5
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2
|
| 1 |
EC50 = 69 nM
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|
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| 2 |
EC50 = 157 nM
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CP0414383
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N-[(3S)-1-(cyclobutylamino)-5-cyclohexyl-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C32H46N4O4
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2
|
| 1 |
EC50 = 70 nM
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| 2 |
EC50 = 97 nM
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CP0414739
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]-4-phenylbutanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C54H89N15O11
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
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CP0543292
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N-[(3S)-1-(cyclobutylamino)-5-cyclohexyl-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C31H46N4O4
|
2
|
| 1 |
EC50 = 81 nM
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|
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| 2 |
EC50 = 282 nM
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CP0414374
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-phenylpentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C31H40N4O4
|
2
|
| 1 |
EC50 = 83 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0480450
|
(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-1-[(2S)-5-(diaminomethylideneamino)-2-[[(2S)-5-oxopyrrolidine-2-carbonyl]amino]pentanoyl]pyrrolidine-2-carbonyl]amino]pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]propanoic acid
Show/Hide
|
C63H104N22O16S
|
1
|
| 1 |
EC50 = 83.18 nM
|
|
|
|
CP0955280
|
(S)-N-(1-(1H-tetrazol-5-ylamino)-1-oxo-5-(piperidin-1-yl)pentan-3-yl)-1-cyclopentyl-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C28H39N9O4
|
1
|
| 1 |
EC50 = 93 nM
|
|
|
|
CP0546507
|
N-[(3S)-5-(2-azabicyclo[2.2.2]octan-2-yl)-1-(cyclobutylamino)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C32H42F3N5O2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0414381
|
N-[(3S)-1-(cyclobutylamino)-5-cyclohexyl-1-oxopentan-3-yl]-1-cyclohexyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C33H48N4O4
|
2
|
| 1 |
EC50 = 101 nM
|
|
|
| 2 |
EC50 = 151 nM
|
|
|
|
CP0558018
|
N-[(3S)-1-[cyclobutyl(methyl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C32H47N5O4
|
1
|
| 1 |
EC50 = 105 nM
|
|
|
|
CP0955279
|
(S)-1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-(4-(piperidin-1-yl)-1-(4H-1,2,4-triazol-3-yl)butan-2-yl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C28H39N7O3
|
1
|
| 1 |
EC50 = 134 nM
|
|
|
|
CP0364315
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C31H46ClN5O4
|
2
|
| 1 |
EC50 = 136 nM
|
|
|
| 2 |
EC50 = 162 nM
|
|
|
|
CP0575625
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C31H45N5O4
|
2
|
| 1 |
EC50 = 136 nM
|
|
|
| 2 |
EC50 = 162 nM
|
|
|
|
CP0546510
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-propan-2-ylphenyl)pyrazole-3-carboxamide
Show/Hide
|
C32H47N5O2
|
1
|
| 1 |
EC50 = 140 nM
|
|
|
|
CP0549122
|
N-[(3S)-5-cyclohexyl-1-oxo-1-(2-oxobutylamino)pentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C31H46N4O5
|
2
|
| 1 |
EC50 = 144 nM
|
|
|
| 2 |
EC50 = 246 nM
|
|
|
|
CP0543273
|
(2R)-N'-cyclobutyl-N-cyclohexyl-2-[[1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]amino]butanediamide
Show/Hide
|
C30H38F3N5O3
|
1
|
| 1 |
EC50 = 152 nM
|
|
|
|
CP0571216
|
N-[(3S)-1-(cyclobutylamino)-5-(3,5-dimethylpyrazol-1-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C30H37F3N6O2
|
1
|
| 1 |
EC50 = 157 nM
|
|
|
|
CP0409281
|
5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)-N-[(2S)-1-oxo-1-(2-oxobutylamino)-4-phenylbutan-2-yl]pyrazole-3-carboxamide
Show/Hide
|
C30H38N4O5
|
2
|
| 1 |
EC50 = 162 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0571211
|
N-[(3S)-1-(cyclobutylamino)-5-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C30H38F3N5O3
|
1
|
| 1 |
EC50 = 162 nM
|
|
|
|
CP0575810
|
5-(2-chlorophenyl)-N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentylpyrazole-3-carboxamide
Show/Hide
|
C29H40ClN5O2
|
1
|
| 1 |
EC50 = 163 nM
|
|
|
|
CP0546403
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-pyrrolidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C30H44ClN5O4
|
1
|
| 1 |
EC50 = 167 nM
|
|
|
|
CP0567984
|
(2R)-N'-cyclobutyl-2-[[1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]amino]-N-(oxan-4-yl)butanediamide
Show/Hide
|
C29H36F3N5O4
|
1
|
| 1 |
EC50 = 169 nM
|
|
|
|
CP0573633
|
N-[(3S)-1-(cyclobutylamino)-5-(oxetane-3-carbonylamino)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C29H36F3N5O4
|
1
|
| 1 |
EC50 = 176 nM
|
|
|
|
CP0559581
|
(3S)-5-(azepan-1-yl)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]pentanoic acid;hydrochloride
Show/Hide
|
C28H41ClN4O5
|
1
|
| 1 |
EC50 = 181 nM
|
|
|
|
CP0548600
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-(1,3-oxazol-2-ylmethylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C31H42N6O5
|
1
|
| 1 |
EC50 = 194 nM
|
|
|
|
CP0568000
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-methoxyphenyl)pyrazole-3-carboxamide
Show/Hide
|
C30H43N5O3
|
1
|
| 1 |
EC50 = 234 nM
|
|
|
|
CP0435011
|
(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]-N-[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[2-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C48H88N18O11
|
1
|
| 1 |
EC50 = 237 nM
|
|
|
|
CP0414380
|
methyl 2-[[(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]pentanoyl]-methylamino]acetate
Show/Hide
|
C31H46N4O6
|
2
|
| 1 |
EC50 = 237 nM
|
|
|
| 2 |
EC50 = 1850 nM
|
|
|
|
CP0546406
|
N-[(3S)-1-(cyclobutylamino)-5-morpholin-4-yl-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C30H44ClN5O5
|
1
|
| 1 |
EC50 = 237 nM
|
|
|
|
CP0473006
|
(3S)-5-cyclohexyl-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C28H39N3O5
|
2
|
| 1 |
EC50 = 238 nM
|
|
|
| 2 |
EC50 = 424 nM
|
|
|
|
CP0546404
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-[(3-methyloxetan-3-yl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C31H45N5O5
|
1
|
| 1 |
EC50 = 241 nM
|
|
|
|
CP0546509
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-ethyl-4-fluorophenyl)pyrazole-3-carboxamide
Show/Hide
|
C31H44FN5O2
|
1
|
| 1 |
EC50 = 265 nM
|
|
|
|
CP0569308
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-ethynylphenyl)pyrazole-3-carboxamide
Show/Hide
|
C31H41N5O2
|
1
|
| 1 |
EC50 = 267 nM
|
|
|
|
CP0543285
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethoxy)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C30H40F3N5O3
|
1
|
| 1 |
EC50 = 272 nM
|
|
|
|
CP0414377
|
(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-propylpyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C26H37N3O5
|
2
|
| 1 |
EC50 = 281 nM
|
|
|
| 2 |
EC50 = 416 nM
|
|
|
|
CP0544201
|
cyclobutyl (3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-piperidin-1-ylpentanoate
Show/Hide
|
C31H44N4O5
|
1
|
| 1 |
EC50 = 285 nM
|
|
|
|
CP0473203
|
methyl 2-[[(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]pentanoyl]amino]acetate
Show/Hide
|
C30H44N4O6
|
2
|
| 1 |
EC50 = 288 nM
|
|
|
| 2 |
EC50 = 684 nM
|
|
|
|
CP0525836
|
5-(2,6-dimethoxyphenyl)-N-[(2S)-1-(2-hydroxybutylamino)-1-oxo-4-phenylbutan-2-yl]-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C30H40N4O5
|
2
|
| 1 |
EC50 = 313 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0414373
|
N-[(3S)-1-(cyclobutylamino)-5-cyclohexyl-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carboxamide
Show/Hide
|
C33H41FN4O4
|
2
|
| 1 |
EC50 = 344 nM
|
|
|
| 2 |
EC50 = 425 nM
|
|
|
|
CP0553001
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-[(1-methylcyclobutyl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C32H47N5O4
|
1
|
| 1 |
EC50 = 352 nM
|
|
|
|
CP0559583
|
N-[(3S)-5-(7-azabicyclo[2.2.1]heptan-7-yl)-1-(cyclobutylamino)-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;hydrochloride
Show/Hide
|
C32H46ClN5O4
|
1
|
| 1 |
EC50 = 363 nM
|
|
|
|
CP0564496
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-methylsulfanylphenyl)pyrazole-3-carboxamide
Show/Hide
|
C30H43N5O2S
|
1
|
| 1 |
EC50 = 377 nM
|
|
|
|
CP0414382
|
(3S)-5-cyclohexyl-3-[[1-cyclohexyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C29H41N3O5
|
2
|
| 1 |
EC50 = 380 nM
|
|
|
| 2 |
EC50 = 518 nM
|
|
|
|
CP0551276
|
(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-pyrrolidin-1-ylpentanoic acid;hydrochloride
Show/Hide
|
C26H37ClN4O5
|
1
|
| 1 |
EC50 = 398 nM
|
|
|
|
CP0487508
|
5-(2,6-dimethoxyphenyl)-N-[(2S)-1-(2-methoxyethylamino)-1-oxo-4-phenylbutan-2-yl]-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
|
C29H38N4O5
|
2
|
| 1 |
EC50 = 411 nM
|
|
|
| 2 |
EC50 > 10000 nM
|
|
|
|
CP0397356
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-6-aminohexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C50H90N16O11
|
1
|
| 1 |
EC50 = 494 nM
|
|
|
|
CP0546511
|
N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)thiophen-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C28H38F3N5O2S
|
1
|
| 1 |
EC50 = 538 nM
|
|
|
|
CP0414745
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[8-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]hexanoyl]amino]octanoylamino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C52H93N15O11
|
1
|
| 1 |
EC50 = 539 nM
|
|
|
|
CP0397354
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C47H83N17O11
|
1
|
| 1 |
EC50 = 637 nM
|
|
|
|
CP0414376
|
(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C27H39N3O5
|
2
|
| 1 |
EC50 = 649 nM
|
|
|
| 2 |
EC50 = 915 nM
|
|
|
|
CP0397357
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-3-methyl-1-oxobutan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C52H90N20O12
|
1
|
| 1 |
EC50 = 691 nM
|
|
|
|
CP0946695
|
(S)-N-(1-((1H-tetrazol-5-yl)methylamino)-1-oxo-5-(piperidin-1-yl)pentan-3-yl)-1-cyclopentyl-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxamide
Show/Hide
|
C29H41N9O4
|
1
|
| 1 |
EC50 = 693 nM
|
|
|
|
CP0552575
|
(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-morpholin-4-ylpentanoic acid;hydrochloride
Show/Hide
|
C26H37ClN4O6
|
1
|
| 1 |
EC50 = 703 nM
|
|
|
|
CP0552571
|
N-[(3S)-1-(cyclobutylamino)-5-(4-methylpiperazin-1-yl)-1-oxopentan-3-yl]-1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carboxamide;dihydrochloride
Show/Hide
|
C31H48Cl2N6O4
|
1
|
| 1 |
EC50 = 721 nM
|
|
|
|
CP0546409
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(2S)-1-(1,3,4-oxadiazol-2-yl)-4-piperidin-1-ylbutan-2-yl]pyrazole-3-carboxamide
Show/Hide
|
C28H38N6O4
|
1
|
| 1 |
EC50 = 779 nM
|
|
|
|
CP0380123
|
(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-(4-fluorophenyl)pyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
|
C29H34FN3O5
|
2
|
| 1 |
EC50 = 800 nM
|
|
|
| 2 |
EC50 = 844 nM
|
|
|
|
CP0551277
|
(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-piperazin-1-ylpentanoic acid;hydrochloride
Show/Hide
|
C26H38ClN5O5
|
1
|
| 1 |
EC50 = 805 nM
|
|
|
|
CP0564482
|
N-[(3S)-1-(cyclobutylamino)-5-(dimethylamino)-1-oxopentan-3-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C27H36F3N5O2
|
1
|
| 1 |
EC50 = 834 nM
|
|
|
|
CP0551757
|
(2S)-N'-cyclobutyl-N-cyclohexyl-2-[[1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carbonyl]amino]-N-methylbutanediamide
Show/Hide
|
C31H40F3N5O3
|
1
|
| 1 |
EC50 = 879 nM
|
|
|
|
CP0576773
|
N-[(2S)-4-(cyclobutylamino)-1-(3,3-difluoropiperidin-1-yl)-4-oxobutan-2-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
|
C29H36F5N5O2
|
1
|
| 1 |
EC50 = 910 nM
|
|
|
|
CP0440865
|
(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
|
C47H84N18O11
|
1
|
| 1 |
EC50 = 936 nM
|
|
|
|
CP0552574
|
1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-(2-methoxyethylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
|
C30H45N5O5
|
1
|
| 1 |
EC50 = 1185 nM
|
|
|
|
CP0543272
|
N-[(2S)-4-(cyclobutylamino)-1-(3,3-difluoropyrrolidin-1-yl)-4-oxobutan-2-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
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C28H34F5N5O2
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1
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| 1 |
EC50 = 1207 nM
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CP0414379
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N-[(2S)-1-(cyclobutylamino)-1-oxo-4-phenylbutan-2-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
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C30H38N4O4
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2
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| 1 |
EC50 = 1260 nM
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| 2 |
EC50 = 3480 nM
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CP0538573
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(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-(diethylamino)pentanoic acid;hydrochloride
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C26H39ClN4O5
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1
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| 1 |
EC50 = 1365 nM
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CP0414740
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamidopropanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
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C50H85N17O12
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1
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| 1 |
EC50 = 1383 nM
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CP0414378
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(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-methylpyrazole-3-carbonyl]amino]pentanoic acid
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C24H33N3O5
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2
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| 1 |
EC50 = 1460 nM
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| 2 |
EC50 = 2550 nM
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CP0525834
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N-[(3S)-5-cyclohexyl-1-(2-methoxyethylamino)-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
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C30H46N4O5
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2
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| 1 |
EC50 = 1700 nM
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| 2 |
EC50 = 3170 nM
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CP0487509
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2-[[(3S)-5-cyclohexyl-3-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]pentanoyl]amino]acetic acid
Show/Hide
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C29H42N4O6
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2
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| 1 |
EC50 = 1850 nM
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| 2 |
EC50 = 4820 nM
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CP0565300
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(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-piperidin-1-ylpentanoic acid;hydrochloride
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C27H39ClN4O5
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1
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| 1 |
EC50 = 2110 nM
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CP0551278
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(3S)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-(2,6-dimethylpiperidin-1-yl)pentanoic acid;hydrochloride
Show/Hide
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C29H43ClN4O5
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1
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| 1 |
EC50 = 2112 nM
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CP0435012
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[2-[(2S)-2-carbamoylpyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
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C50H87N21O12
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1
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| 1 |
EC50 = 2350 nM
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CP0563551
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1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-[2-methoxyethyl(methyl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
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C31H47N5O5
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1
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| 1 |
EC50 = 2411 nM
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CP0946696
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(S)-N-(1-(2-(1H-tetrazol-5-yl)ethylamino)-1-oxo-5-(piperidin-1-yl)pentan-3-yl)-1-cyclopentyl-5-(2,6-dimethoxyphenyl)-1H-pyrazole-3-carboxamide
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C30H43N9O4
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1
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| 1 |
EC50 = 2642 nM
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CP0567749
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2-methylsulfonylphenyl)pyrazole-3-carboxamide
Show/Hide
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C30H43N5O4S
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1
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| 1 |
EC50 = 2966 nM
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CP0546505
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,6-dimethylphenyl)pyrazole-3-carboxamide
Show/Hide
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C31H45N5O2
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1
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| 1 |
EC50 = 3841 nM
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CP0546408
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1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-[(1-methylcyclopropyl)amino]-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
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C31H45N5O4
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1
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| 1 |
EC50 = 5000 nM
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CP0543284
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(4-ethoxy-2,6-difluorophenyl)pyrazole-3-carboxamide
Show/Hide
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C31H43F2N5O3
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1
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| 1 |
EC50 = 5085 nM
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CP0544914
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N-[(2S)-4-(cyclobutylamino)-1-[cyclohexyl(methyl)amino]-4-oxobutan-2-yl]-1-cyclopentyl-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
Show/Hide
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C31H42F3N5O2
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1
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| 1 |
EC50 = 5125 nM
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CP0525798
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N-[(3S)-1-amino-5-cyclohexyl-1-oxopentan-3-yl]-5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carboxamide
Show/Hide
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C27H40N4O4
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2
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| 1 |
EC50 = 5750 nM
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| 2 |
EC50 > 10000 nM
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CP0546875
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-thiophen-2-ylpyrazole-3-carboxamide
Show/Hide
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C27H39N5O2S
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1
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| 1 |
EC50 = 5856 nM
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CP0546405
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1-cyclopentyl-5-(2,6-dimethoxyphenyl)-N-[(3S)-1-(2-oxa-6-azaspiro[3.3]heptan-6-yl)-1-oxo-5-piperidin-1-ylpentan-3-yl]pyrazole-3-carboxamide
Show/Hide
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C32H45N5O5
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1
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| 1 |
EC50 = 5892 nM
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CP0571613
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(3S)-5-(7-azabicyclo[2.2.1]heptan-7-yl)-3-[[1-cyclopentyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]pentanoic acid;hydrochloride
Show/Hide
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C28H39ClN4O5
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1
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| 1 |
EC50 = 7562 nM
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CP0473204
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(3S)-5-cyclohexyl-3-[[1-(cyclohexylmethyl)-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]pentanoic acid
Show/Hide
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C30H43N3O5
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1
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| 1 |
EC50 > 10000 nM
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CP0516492
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(2S)-2-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]-4-phenylbutanoic acid
Show/Hide
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C26H31N3O5
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1
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| 1 |
EC50 > 10000 nM
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CP0525797
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(3S)-3-[[1-cycloheptyl-5-(2,6-dimethoxyphenyl)pyrazole-3-carbonyl]amino]-5-cyclohexylpentanoic acid
Show/Hide
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C30H43N3O5
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1
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| 1 |
EC50 > 10000 nM
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CP0532229
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(3S)-3-[[5-(2,6-dimethoxyphenyl)-1-(2-methylpropyl)pyrazole-3-carbonyl]amino]-5-phenylpentanoic acid
Show/Hide
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C27H33N3O5
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1
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| 1 |
EC50 > 10000 nM
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CP0543270
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(1,3-thiazol-4-yl)pyrazole-3-carboxamide
Show/Hide
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C26H38N6O2S
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1
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| 1 |
EC50 > 10000 nM
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CP0543283
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-[4-fluoro-2-(2,2,2-trifluoroethoxy)phenyl]pyrazole-3-carboxamide
Show/Hide
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C31H41F4N5O3
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1
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| 1 |
EC50 > 10000 nM
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CP0546506
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(2,4,6-trifluorophenyl)pyrazole-3-carboxamide
Show/Hide
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C29H38F3N5O2
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1
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| 1 |
EC50 > 10000 nM
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CP0550099
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-pyridin-2-ylpyrazole-3-carboxamide
Show/Hide
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C28H40N6O2
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1
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| 1 |
EC50 > 10000 nM
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CP0568002
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(3,5-dimethyl-1,2-oxazol-4-yl)pyrazole-3-carboxamide
Show/Hide
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C28H42N6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0571239
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-(1-oxidopyridin-1-ium-2-yl)pyrazole-3-carboxamide
Show/Hide
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C28H40N6O3
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1
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| 1 |
EC50 > 10000 nM
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CP0571690
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-phenylpyrazole-3-carboxamide
Show/Hide
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C29H41N5O2
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1
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| 1 |
EC50 > 10000 nM
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CP0578219
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N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentyl-5-pyrimidin-5-ylpyrazole-3-carboxamide
Show/Hide
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C27H39N7O2
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1
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| 1 |
EC50 > 10000 nM
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CP0579888
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5-[2,6-bis(2,2,2-trifluoroethoxy)phenyl]-N-[(3S)-1-(cyclobutylamino)-1-oxo-5-piperidin-1-ylpentan-3-yl]-1-cyclopentylpyrazole-3-carboxamide
Show/Hide
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C33H43F6N5O4
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1
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| 1 |
EC50 > 10000 nM
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CP0499222
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-6-aminohexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C49H74N12O12S
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1
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| 1 |
EC50 > 31622.78 nM
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CP0535757
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-2-acetamido-6-aminohexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C34H51N7O8S
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1
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| 1 |
EC50 > 31622.78 nM
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CP0481413
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Show/Hide
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C37H65N17O9
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1
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| 1 |
EC50 > 3000 nM
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CP0481414
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-acetamido-6-[(2,2,2-trifluoroacetyl)amino]hexanoyl]pyrrolidine-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C52H89F3N16O12
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1
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| 1 |
EC50 > 3000 nM
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CP0495177
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(2S)-2-amino-N-[(2S)-5-(diaminomethylideneamino)-1-[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1,6-diamino-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxopentan-2-yl]pentanediamide
Show/Hide
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C43H77N19O10
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1
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| 1 |
EC50 > 3000 nM
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CP0495178
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Show/Hide
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C31H58N14O8
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1
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| 1 |
EC50 > 3000 nM
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CP0548973
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(2S)-1-[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[8-[[(2S)-1-[(2S)-2-acetamido-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]octanoylamino]-4-methylpentanoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]acetyl]-N-[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
Show/Hide
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C49H86N14O11
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1
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| 1 |
EC50 > 3000 nM
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CP0574669
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(2S)-2-amino-N-[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pentanediamide
Show/Hide
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C45H80N20O11
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1
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| 1 |
EC50 > 3000 nM
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CP0210766
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(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-1-[2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-5-amino-2-[[(2S)-5-carbamimidamido-2-[[(2S)-5-carbamimidamido-2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-3-phenylpropanoyl]amino]pentanoyl]amino]pentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]pyrrolidine-2-carbonyl]amino]-5-carbamimidamidopentanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-4-yl)propanoyl]amino]hexanoyl]amino]acetyl]pyrrolidine-2-carbonyl]amino]-4-methylsulfanylbutanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid
Show/Hide
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C96H156N34O20S
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1
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| 1 |
Ki = 0.04 nM
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CP0382476
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[[4-(diethylamino)phenyl]-(4-diethylazaniumylidenecyclohexa-2,5-dien-1-ylidene)methyl]benzenesulfonate;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C65H80F9N11O14S3
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1
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| 1 |
Ki = 89 nM
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CP0467936
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)methylamino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
Show/Hide
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C60H78N11O9S3+
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1
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| 1 |
Ki = 180 nM
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CP0457156
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-benzylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C65H82N11O9S3+3
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1
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| 1 |
Ki = 270 nM
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CP0482575
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5-[6-[[(5S)-5-[[2-(2-amino-3-methyl-1,3-thiazol-3-ium-4-yl)acetyl]amino]-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-1-ium-4-yl)amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]carbamoylamino]hexylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate;2,2,2-trifluoroacetate
Show/Hide
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C72H92F9N13O16S3
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1
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| 1 |
Ki = 310 nM
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CP0457157
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate;2,2,2-trifluoroacetate;2,2,2-trifluoroacetic acid
Show/Hide
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C65H78F9N11O15S3
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1
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| 1 |
Ki = 400 nM
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CP0487517
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5-[12-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylamino]dodecylsulfonyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
Show/Hide
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C72H101N12O10S3+
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1
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| 1 |
Ki = 400 nM
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CP0416175
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5-[12-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-1-ium-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-3H-1,3-thiazol-3-ium-4-yl)acetyl]amino]-6-oxohexyl]carbamoylamino]dodecylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate;2,2,2-trifluoroacetate
Show/Hide
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C72H104N13O10S3+3
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1
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| 1 |
Ki = 430 nM
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CP0411701
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2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]-5-[[(5S)-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-[[(2S)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]sulfamoyl]benzenesulfonate
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C48H65N9O9S3
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1
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| 1 |
Ki = 450 nM
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CP0867360
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5-(N-(12-(3-((S)-6-((S)-3-(1-benzyl-3-methyl-1H-imidazol-3-ium-4-yl)-1-(1-methylpiperidinium-4-ylamino)-1-oxopropan-2-ylamino)-5-(2-(2-iminio-3-methyl-2,3-dihydrothiazol-4-yl)acetamido)-6-oxohexyl)ureido)dodecyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate
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C72H102N13O10S3+
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1
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| 1 |
Ki = 690 nM
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CP0382475
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5-[[(5S)-5-[[2-(2-amino-1,3-thiazol-4-yl)acetyl]amino]-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C58H74N11O9S3+
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1
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| 1 |
Ki = 850 nM
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CP0864956
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5-(N-((S)-6-((S)-3-(1-benzyl-1H-imidazol-3-ium-4-yl)-1-(1-methylpiperidin-4-ylamino)-1-oxopropan-2-ylamino)-5-(2-(2-imino-3-methyl-2,3-dihydrothiazol-4-yl)acetamido)-6-oxohexyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate
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C58H73N11O9S3
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1
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| 1 |
Ki = 960 nM
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CP0467934
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5-[[(5S)-6-[[(2S)-1-[[(2S)-1-amino-1-oxopropan-2-yl]amino]-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C56H70N11O10S3+
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1
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| 1 |
Ki = 970 nM
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CP0475317
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5-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-(oxan-4-ylamino)-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C58H73N10O10S3+
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1
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| 1 |
Ki = 980 nM
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CP0484085
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5-[[(5S)-5-acetamido-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-6-oxohexyl]sulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C55H72N9O9S2+
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1
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| 1 |
Ki = 1200 nM
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CP0539568
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5-[12-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1,1-dimethylpiperidin-1-ium-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]carbamoylamino]dodecylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C73H105N13O10S3+2
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1
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| 1 |
Ki = 1400 nM
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CP0904667
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5-(N-(12-(3-((S)-6-((S)-3-(1-benzyl-1H-imidazol-3-ium-4-yl)-1-(1-methylpiperidinium-4-ylamino)-1-oxopropan-2-ylamino)-5-(2-(2-imino-3-methyl-2,3-dihydrothiazol-4-yl)acetamido)-6-oxohexyl)ureido)dodecyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate
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C71H99N13O10S3
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1
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| 1 |
Ki = 1500 nM
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CP0900188
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5-(N-(12-(3-((S)-6-((S)-3-(1-benzyl-1H-imidazol-3-ium-4-yl)-1-(1,1-dimethylpiperidinium-4-ylamino)-1-oxopropan-2-ylamino)-5-(2-(2-imino-3-methyl-2,3-dihydrothiazol-4-yl)acetamido)-6-oxohexyl)ureido)dodecyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate
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C72H102N13O10S3+
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1
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| 1 |
Ki = 3000 nM
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CP0914904
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5-(N-(12-(3-((S)-6-((S)-3-(1-benzyl-1H-imidazol-3-ium-4-yl)-1-(1-methylpiperidinium-4-ylamino)-1-oxopropan-2-ylamino)-5-(2-(2-imino-2,3-dihydrothiazol-4-yl)acetamido)-6-oxohexyl)ureido)dodecyl)sulfamoyl)-2-(6-(diethylamino)-3-(diethyliminio)-3H-xanthen-9-yl)benzenesulfonate
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C70H97N13O10S3
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1
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| 1 |
Ki = 9000 nM
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CP0480381
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(2S)-6-acetamido-2-[[2-(2-amino-3-methyl-1,3-thiazol-3-ium-4-yl)acetyl]amino]-N-[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-1-ium-4-yl)amino]-1-oxopropan-2-yl]hexanamide;2,2,2-trifluoroacetate
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C40H52F9N9O10S
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1
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| 1 |
Ki > 100000 nM
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CP0484083
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5-[4-[[(5S)-6-[[(2S)-3-(1-benzyl-3-methylimidazol-1-ium-4-yl)-1-[(1-methylpiperidin-4-yl)amino]-1-oxopropan-2-yl]amino]-5-[[2-(2-imino-3-methyl-1,3-thiazol-4-yl)acetyl]amino]-6-oxohexyl]amino]butylsulfamoyl]-2-[3-(diethylamino)-6-diethylazaniumylidenexanthen-9-yl]benzenesulfonate
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C63H85N12O9S3+
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1
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| 1 |
Ki > 100000 nM
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