Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyclopentyl-N-[(3S)-5-(3,3-difluoropiperidin-1-yl)-1-oxo-1-(2H-tetrazol-5-ylamino)pentan-3-yl]-5-[2-(trifluoromethyl)phenyl]pyrazole-3-carboxamide
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 PubChem ID
CID: 168288270
Canonical SMILES
FC(F)(F)c1ccccc1-c1cc(nn1C1CCCC1)C(=O)N[C@@H](CCN1CCCC(F)(F)C1)CC(=O)Nc1nnn[nH]1
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Compound Formula C27H32F5N9O2
Compound Structure
Protein Name
 Protein Info 
Apelin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neuropeptide receptor
Uniprot ID
P35414
Gene Name
APLNR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 6.5 nM
   TI
   LI
   LO
   TS
2
EC50 = 24 nM
   TI
   LI
   LO
   TS
CL000026 CHO-K1
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 463 nM
   TI
   LI
   LO
   TS