Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT05074 , NADPH oxidase 4
Gene Name NOX4
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID Q9NPH5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT05074
 
Compound ID Compound Name Compound Formula
CP0931898
2-(2-Chlorophenyl)-10-(pyridin-2-ylmethyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C22H21Cl2N5O2
 1
1
Ki = 67 nM
   TI
   LI
   LO
   TS
CP0676506
10-benzyl-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C23H22Cl2N4O2
 1
1
Ki = 72 nM
   TI
   LI
   LO
   TS
CP0891668
10-(2-Chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C23H21Cl3N4O2
 1
1
Ki = 76 nM
   TI
   LI
   LO
   TS
CP0931896
2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C16H16Cl2N4O2
 1
1
Ki = 87 nM
   TI
   LI
   LO
   TS
CP0910838
2-(2-Methoxyphenyl)-10-(pyridin-2-ylmethyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C23H24ClN5O3
 1
1
Ki = 93 nM
   TI
   LI
   LO
   TS
CP0937033
2-(2-Chlorophenyl)-10-(pyridin-3-ylmethyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C22H21Cl2N5O2
 1
1
Ki = 94 nM
   TI
   LI
   LO
   TS
CP0855809
10-(3-Chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C23H21Cl3N4O2
 1
1
Ki = 101 nM
   TI
   LI
   LO
   TS
CP0459997
tert-butyl 4-(2-chlorophenyl)-3,8-dioxo-4,5,9,13-tetrazatricyclo[7.5.0.02,6]tetradeca-1,6-diene-13-carboxylate
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C21H23ClN4O4
 1
1
Ki = 103 nM
   TI
   LI
   LO
   TS
CP0917567
10-(4-Chlorobenzyl)-2-(2-chlorophenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C23H21Cl3N4O2
 1
1
Ki = 103 nM
   TI
   LI
   LO
   TS
CP0853723
2-(2-Chlorophenyl)-10-(2-methoxybenzyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C24H24Cl2N4O3
 1
1
Ki = 111 nM
   TI
   LI
   LO
   TS
CP0943839
2-(2-Chlorophenyl)-10-(furan-3-ylmethyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C21H20Cl2N4O3
 1
1
Ki = 111 nM
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   LI
   LO
   TS
CP0868711
2-(2-Chloro-phenyl)-9-(3-methoxy-benzyl)-2,3,7,8,9,10-hexahydro-6H-2,3,5a,9-tetraaza-cyclohepta[e]indene-1,5-dione hydrochloride
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C24H24Cl2N4O3
 1
1
Ki = 112 nM
   TI
   LI
   LO
   TS
CP0855810
2-(2-Chlorophenyl)-10-(4-methoxybenzyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C24H24Cl2N4O3
 1
1
Ki = 116 nM
   TI
   LI
   LO
   TS
CP0931897
10-(3-Methoxybenzyl)-2-(2-methoxyphenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C25H27ClN4O4
 1
1
Ki = 131 nM
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   LI
   LO
   TS
CP0859309
9-benzyl-2-(2-chlorophenyl)-2,3,7,8,9,10-hexahydropyrazolo[4',3':3,4]pyrido[1,2-a]pyrazine-1,5-dione hydrochloride
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C22H20Cl2N4O2
 1
1
Ki = 142 nM
   TI
   LI
   LO
   TS
CP0919256
10-Benzyl-2-(2-methoxyphenyl)-2,3,8,9,10,11-hexahydro-1H-pyrazolo[4',3':3,4]pyrido[1,2-a][1,4]diazepine-1,5(7H)-dione hydrochloride
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C24H25ClN4O3
 1
1
Ki = 144 nM
   TI
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   LO
   TS
CP0525079
4-(2-chlorophenyl)-12-oxa-4,5,9-triazatricyclo[7.4.0.02,6]trideca-1,6-diene-3,8-dione
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C15H12ClN3O3
 1
1
Ki = 156 nM
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   TS