| Compound ID |
Compound Name |
Compound Formula |
|
CP0415983
|
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
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|
C18H22F3N3O4S
|
1
|
| 1 |
IC50 > 6700 nM
|
|
|
|
CP0362924
|
(2R,3R,4S,5R)-2-[6-[[(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C17H23N5O4
|
1
|
| 1 |
Ki = 0.14 nM
|
|
|
|
CP0534305
|
(2R,3R,4S,5S)-2-[6-[[(1R,4S)-2-bicyclo[2.2.1]heptanyl]amino]purin-9-yl]-5-(chloromethyl)oxolane-3,4-diol
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|
C17H22ClN5O3
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
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CP0077413
|
(2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin-9-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol
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|
C15H20ClN5O4
|
1
|
| 1 |
Ki = 0.21 nM
|
|
|
|
CP0049200
|
(2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C15H21N5O4
|
1
|
| 1 |
Ki = 0.22 nM
|
|
|
|
CP0204638
|
(2R,3R,4S,5R)-2-[6-[di(cyclobutyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C19H27N5O4
|
1
|
| 1 |
Ki = 0.37 nM
|
|
|
|
CP0039348
|
(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide
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|
C12H16N6O4
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0169089
|
(1S,2R,3S,4R,5S)-4-[6-[[(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-N-cyclopropyl-2,3-dihydroxybicyclo[3.1.0]hexane-1-carboxamide
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|
C22H27ClN6O3
|
1
|
| 1 |
Ki = 0.45 nM
|
|
|
|
CP0169091
|
(1R,2R,3S,4R,5S)-4-[6-[di(cyclobutyl)methylamino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol
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|
C21H29N5O3
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0139864
|
(2R,3R,4S,5R)-2-[2-chloro-6-[di(cyclobutyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
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|
C19H26ClN5O4
|
1
|
| 1 |
Ki = 0.65 nM
|
|
|
|
CP0169090
|
(2S,3S,4R,5R)-2-(chloromethyl)-5-[6-[di(cyclobutyl)methylamino]purin-9-yl]oxolane-3,4-diol
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|
C19H26ClN5O3
|
1
|
| 1 |
Ki = 0.71 nM
|
|
|
|
CP0139869
|
(1S,2R,3S,4R,5S)-1-(chloromethyl)-4-[6-[di(cyclobutyl)methylamino]purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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|
C21H28ClN5O2
|
1
|
| 1 |
Ki = 1.05 nM
|
|
|
|
CP0169097
|
(1R,2R,3S,4R,5S)-4-[6-[[(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol
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|
C19H24ClN5O3
|
1
|
| 1 |
Ki = 1.05 nM
|
|
|
|
CP0069838
|
(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
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|
C26H26N6O4
|
1
|
| 1 |
Ki = 1.45 nM
|
|
|
|
CP0440591
|
(1S,2R,3S,4R,5S)-4-[6-[[(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-2,3-dihydroxy-N-(2-hydroxyethyl)bicyclo[3.1.0]hexane-1-carboxamide
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|
C21H27ClN6O4
|
1
|
| 1 |
Ki = 1.56 nM
|
|
|
|
CP0266847
|
(1S,2R,3S,4R,5S)-4-[6-[[(1R,2S,4S)-2-bicyclo[2.2.1]heptanyl]amino]-2-chloropurin-9-yl]-1-(chloromethyl)bicyclo[3.1.0]hexane-2,3-diol
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|
C19H23Cl2N5O2
|
1
|
| 1 |
Ki = 1.86 nM
|
|
|
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CP0139868
|
(1R,2R,3S,4R,5S)-4-[2-chloro-6-[di(cyclobutyl)methylamino]purin-9-yl]-1-(hydroxymethyl)bicyclo[3.1.0]hexane-2,3-diol
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|
C21H28ClN5O3
|
1
|
| 1 |
Ki = 2.47 nM
|
|
|
|
CP0354472
|
(2R,3R,4S,5S)-2-[6-[di(cyclobutyl)methylamino]purin-9-yl]-5-(ethylsulfanylmethyl)oxolane-3,4-diol
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|
C21H31N5O3S
|
1
|
| 1 |
Ki = 3.58 nM
|
|
|
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CP0169100
|
(1R,2R,3S,4R,5S)-4-[2-chloro-6-(dicyclopropylmethylamino)purin-9-yl]bicyclo[3.1.0]hexane-2,3-diol
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|
C18H22ClN5O2
|
1
|
| 1 |
Ki = 5.2 nM
|
|
|
|
CP0169092
|
(1S,2R,3S,4R,5S)-4-[2-chloro-6-[di(cyclobutyl)methylamino]purin-9-yl]-1-(chloromethyl)bicyclo[3.1.0]hexane-2,3-diol
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|
C21H27Cl2N5O2
|
1
|
| 1 |
Ki = 11.2 nM
|
|
|
|
CP0204631
|
1-[(1S,2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-bicyclo[3.1.0]hexanyl]-1,2,4-triazole-3-carboxamide
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|
C10H14N4O4
|
1
|
| 1 |
Ki = 25.2 nM
|
|
|
|
CP0424466
|
8-[4-[4-[(3-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C25H27BrN6O4S
|
1
|
| 1 |
Ki = 107 nM
|
|
|
|
CP0065233
|
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
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|
C14H14N4O5S
|
1
|
| 1 |
Ki = 591 nM
|
|
|
|
CP0420800
|
8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-methyl-1-propyl-7H-purine-2,6-dione
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|
C25H27ClN6O4S
|
1
|
| 1 |
Ki = 1520 nM
|
|
|
|
CP0204629
|
(1S,2R,3S,4R,5S)-4-[2-chloro-6-[di(cyclobutyl)methylamino]purin-9-yl]-1-[(2-fluorophenyl)sulfanylmethyl]bicyclo[3.1.0]hexane-2,3-diol
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|
C27H31ClFN5O2S
|
1
|
| 1 |
Ki = 2490 nM
|
|
|
|
CP0169094
|
methyl 1-[(1S,2R,3S,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-2-bicyclo[3.1.0]hexanyl]-1,2,4-triazole-3-carboxylate
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|
C11H15N3O5
|
1
|
| 1 |
Ki = 2990 nM
|
|
|
|
CP0014362
|
Adenosine receptor agonist, 16
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|
C8H12N4O5
|
1
|
| 1 |
Ki = 4430 nM
|
|
|
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CP0420820
|
8-[4-[4-(3-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C24H25FN6O4S
|
1
|
| 1 |
Ki > 300 nM
|
|
|
|
CP0420803
|
8-[4-[4-(4-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C24H25BrN6O4S
|
1
|
| 1 |
Ki > 1000 nM
|
|
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