Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
 Cell Line Info 
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT04916 , Growth hormone secretagogue receptor type 1
 Protein Info 
Gene Name GHSR
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID O08725
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011
 Cell Line Info 
 Protein ID: PT04916
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0849540
 Compound Info 
3-(Difluoromethyl)-4-methylbenzyl 2-((benzo[d][1,3]-dioxol-5-ylmethyl)amino)-5-(3-hydroxy-3-methylbut-1-yn-1-yl)nicotinate
   Show/Hide
C28H27F2N3O4
  2
1
IC50 = 0.28 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 13 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0884346
 Compound Info 
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(((S)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)methyl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)nicotinamide
   Show/Hide
C34H36N4O5
  1
1
IC50 = 0.96 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0869061
 Compound Info 
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)-N-(2-phenoxyethyl)nicotinamide
   Show/Hide
C33H36N4O4
  1
1
IC50 = 2.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0865055
 Compound Info 
5-((1R,5S)-8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-((benzo[d][1,3]dioxol-5-ylmethyl)amino)-N-(3-chloro-4-methoxybenzyl)nicotinamide
   Show/Hide
C32H33ClN4O5
  2
1
IC50 = 5.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0873715
 Compound Info 
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-N-(3-chloro-4-methoxybenzyl)-2-(((2,3-dihydrobenzofuran-6-yl)methyl)amino)nicotinamide
   Show/Hide
C33H35ClN4O4
  1
1
IC50 = 5.9 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0852605
 Compound Info 
5-(3-Acetamido-3-methylbut-1-yn-1-yl)-2-((benzo[d]-[1,3]dioxol-5-ylmethyl)amino)-N-(3-chloro-4-methoxybenzyl)-nicotinamide
   Show/Hide
C29H29ClN4O5
  2
1
IC50 = 6.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0865025
 Compound Info 
5-(8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-((benzo-[d][1,3]dioxol-5-ylmethyl)amino)-N-(2-phenoxyethyl)nicotinamide
   Show/Hide
C32H34N4O5
  1
1
IC50 = 9.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS