Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-((1R,5S)-8-Acetyl-8-azabicyclo[3.2.1]oct-3-en-3-yl)-2-((benzo[d][1,3]dioxol-5-ylmethyl)amino)-N-(3-chloro-4-methoxybenzyl)nicotinamide
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 PubChem ID
CID: 122182047
Canonical SMILES
COc1ccc(CNC(=O)c2cc(C3=C[C@@H]4CC[C@H](C3)N(C(C)=O)C4)cnc2NCc2ccc3c(c2)OCO3)cc1Cl
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Compound Formula C32H33ClN4O5
Compound Structure
Protein Name
 Protein Info 
Growth hormone secretagogue receptor type 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
GRP-related receptor
Uniprot ID
O08725
Gene Name
GHSR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 5.6 nM
   TI
   LI
   LO
   TS
2
IC50 = 100 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 9.8 nM
   TI
   LI
   LO
   TS