| Compound ID |
Compound Name |
Compound Formula |
|
CP0422261
|
4'-(2-furyl)-N-pyridin-3-yl-4,5'-bipyrimidin-2'-amine
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|
C17H12N6O
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0415983
|
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
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|
C18H22F3N3O4S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0099922
|
N-[5-(3-fluoropyridin-4-yl)-6-pyridin-3-ylpyrazin-2-yl]cyclopropanecarboxamide
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|
C18H14FN5O
|
1
|
| 1 |
IC50 = 512 nM
|
|
|
|
CP0377686
|
8-(4-(4-(4-Chlorophenyl)piperazine-1-sulfonyl)phenyl)-1-propyl-3,7-dihydropurine-2,6-dione
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|
C24H25ClN6O4S
|
1
|
| 1 |
Kd = 0.351 nM
|
|
|
|
CP0420803
|
8-[4-[4-(4-bromophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C24H25BrN6O4S
|
1
|
| 1 |
Ki = 0.131 nM
|
|
|
|
CP0424466
|
8-[4-[4-[(3-bromophenyl)methyl]piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C25H27BrN6O4S
|
1
|
| 1 |
Ki = 0.901 nM
|
|
|
|
CP0420820
|
8-[4-[4-(3-fluorophenyl)piperazin-1-yl]sulfonylphenyl]-1-propyl-3,7-dihydropurine-2,6-dione
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|
C24H25FN6O4S
|
1
|
| 1 |
Ki = 0.926 nM
|
|
|
|
CP0391881
|
N-[2-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)ethyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
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|
C31H34BF2N7O4
|
1
|
| 1 |
Ki = 1.32 nM
|
|
|
|
CP0069838
|
(4-Cyano-phenyl)-carbamic acid 4-(2,6-dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-phenyl ester
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|
C26H26N6O4
|
1
|
| 1 |
Ki = 3.12 nM
|
|
|
|
CP0420800
|
8-[4-[4-(4-chlorophenyl)piperazin-1-yl]sulfonylphenyl]-3-methyl-1-propyl-7H-purine-2,6-dione
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|
C25H27ClN6O4S
|
1
|
| 1 |
Ki = 8.34 nM
|
|
|
|
CP0065233
|
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
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|
C14H14N4O5S
|
1
|
| 1 |
Ki = 1940 nM
|
|
|
|
CP0043620
|
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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|
C8H10N4O2
|
1
|
| 1 |
Ki = 23000 nM
|
|
|
