Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT03803 , Alcohol dehydrogenase class-3
Gene Name ADH5
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P11766
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT03803
 
Compound ID Compound Name Compound Formula
CP0544449
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one
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C24H21N3O5
 1
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
CP0407171
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(pyridin-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C21H18N4O5S
 1
1
IC50 = 16 nM
   TI
   LI
   LO
   TS
CP0413974
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C22H19N3O5S
 1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
CP0397812
US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C22H19N3O5S
 1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CP0406431
US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(pyridin-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C21H18N4O5S
 1
1
IC50 = 24 nM
   TI
   LI
   LO
   TS
CP0468280
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C23H20N4O5
 1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
CP0531133
US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one
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C24H21N3O5
 1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
CP0543353
US8906933, (S)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methyl-1H-pyrazol-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C20H19N5O5S
 1
1
IC50 = 35 nM
   TI
   LI
   LO
   TS
CP0518418
US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methyl-1H-pyrazol-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C20H19N5O5S
 1
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
CP0431790
US8906933, 4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C23H20N4O5
 1
1
IC50 = 43 nM
   TI
   LI
   LO
   TS
CP0550613
US8906933, (S)-3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid
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C22H21N3O5S
 1
1
IC50 = 67 nM
   TI
   LI
   LO
   TS
CP0414733
US8906933, 3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid
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C22H21N3O5S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0468165
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-phenyl-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C22H19N3O5S
 1
1
IC50 = 1820 nM
   TI
   LI
   LO
   TS
CP0429647
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(pyridin-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C21H18N4O5S
 1
1
IC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0396437
US8906933, (R)-3-ethoxy-2-hydroxy-5-(2-oxo-6-(pyridin-3-yl)-5-(thiophen-3-yl)-1,2,3,4-tetrahydropyrimidin-4-yl)benzoic acid
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C22H21N3O5S
 1
1
IC50 = 3170 nM
   TI
   LI
   LO
   TS
CP0429601
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5-phenyl-6-(pyridin-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C23H20N4O5
 1
1
IC50 = 6020 nM
   TI
   LI
   LO
   TS
CP0435232
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-5,6-diphenyl-3,4-dihydropyrimidin-2(1H)-one
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C24H21N3O5
 1
1
IC50 = 19720 nM
   TI
   LI
   LO
   TS
CP0385677
US8906933, (R)-4-(3-ethoxy-4-hydroxy-5-nitrophenyl)-6-(1-methyl-1H-pyrazol-3-yl)-5-(thiophen-3-yl)-3,4-dihydropyrimidin-2(1H)-one
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C20H19N5O5S
 1
1
IC50 = 31000 nM
   TI
   LI
   LO
   TS