Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT03657 , Solute carrier organic anion transporter family member 1B3
Gene Name SLCO1B3
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID Q9NPD5
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT03657
 
Compound ID Compound Name Compound Formula
CP0182760
Sarsasapogenin
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C27H44O3
 2
1
IC50 = 104.71 nM
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2
Ki = 80 nM
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CP0052039
18beta-glycyrrhetic acid
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C30H46O4
 2
1
IC50 = 549.54 nM
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2
Ki = 420 nM
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CP0166263
NORSTICTIC ACID
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C18H12O9
 2
1
IC50 = 549.54 nM
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2
Ki = 420 nM
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CP0870363
BUSSEIN
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C43H54O18
 2
1
IC50 = 691.83 nM
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2
Ki = 530 nM
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CP0423174
[(1R,3Z,6S,7R,9R,10R,15R,16S,19S,20S)-18-acetyloxy-6-(furan-3-yl)-9,19,20-trimethoxy-3-(1-methoxy-2-methylpropylidene)-16-(2-methoxy-2-oxoethyl)-7,12,15,17-tetramethyl-4-oxo-5,11,13,21-tetraoxaheptacyclo[10.8.1.114,17.01,10.02,7.010,15.014,19]docosan-8-yl] 2-methylpropanoate
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C43H58O16
 2
1
IC50 = 724.44 nM
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2
Ki = 560 nM
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CP0051629
4-hydroxy-3-(4-hydroxyphenyl)-5-methoxy-8,8-dimethyl-6-(3-methylbut-2-enyl)pyrano[2,3-h]chromen-2-one
   Show/Hide
C26H26O6
 2
1
IC50 = 741.31 nM
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2
Ki = 560 nM
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CP0077816
LASALOCID A SODIUM
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C34H53NaO8
 2
1
IC50 = 776.25 nM
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2
Ki = 590 nM
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CP0391465
[(1R,2R,7S,8R,9S,17S,18S,20R,22S)-8-acetyloxy-17-(furan-3-yl)-3,7-dihydroxy-22-(2-methoxy-2-oxoethyl)-2,5,11,18-tetramethyl-20-(2-methylbutanoyloxy)-15-oxo-10,12,16,21-tetraoxaheptacyclo[9.9.1.12,5.01,9.03,7.09,13.013,18]docosan-6-yl] 2,3-dimethyloxirane-2-carboxylate
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C41H52O17
 2
1
IC50 = 776.25 nM
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2
Ki = 600 nM
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CP0272224
4-Epi-Hederagenin
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C30H48O4
 2
1
IC50 = 891.25 nM
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2
Ki = 680 nM
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CP0071410
Benicar
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C29H30N6O6
 2
1
IC50 = 977.24 nM
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2
Ki = 750 nM
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CP0018902
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
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C20H32O2
 2
1
IC50 = 1071.52 nM
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2
Ki = 820 nM
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CP0043276
CAS_114798-26-4
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C22H23ClN6O
 2
1
IC50 = 1148.15 nM
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2
Ki = 890 nM
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CP0370401
(9beta,10alpha,11alpha,14beta,16alpha,17alpha)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl furan-2-carboxylate
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C27H30Cl2O6
 2
1
IC50 = 1148.15 nM
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2
Ki = 870 nM
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CP0650250
SID855631
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C44H43ClN2O8
 2
1
IC50 = 1230.27 nM
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2
Ki = 940 nM
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CP0083167
4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
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C33H30N4O2
 2
1
IC50 = 1258.93 nM
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2
Ki = 960 nM
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CP0433032
[(1S,4bS,5R,6aS,8R,10aR,10bS,12aS)-5-acetyloxy-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-8-yl] acetate
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C30H40O7
 2
1
IC50 = 1412.54 nM
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2
Ki = 1080 nM
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CP0027182
3-hydroxy-9-methoxy-6-oxo-7-pentanoyl-1-pentylbenzo[b][1,4]benzodioxepine-2-carboxylic acid
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C25H28O8
 2
1
IC50 = 1621.81 nM
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2
Ki = 1250 nM
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CP0408703
CARBENOXOLONE DISODIUM
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C34H48Na2O7
 2
1
IC50 = 1905.46 nM
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2
Ki = 1480 nM
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CP0379894
BRL-1702
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C19H18Cl2N3NaO6S
 2
1
IC50 = 1995.26 nM
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2
Ki = 1550 nM
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CP0391187
ERYTHROMYCIN ETHYLSUCCINATE
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C43H75NO16
 2
1
IC50 = 2089.3 nM
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2
Ki = 1610 nM
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CP0391198
(4R)-4-[(E)-3-carboxybut-2-enyl]-14-hydroxy-6,6,18-trimethyl-21-(3-methylbut-2-enyl)-18-(4-methylpent-3-enyl)-12-oxo-2,5,19-trioxapentacyclo[11.8.0.03,7.03,11.015,20]henicosa-1(13),10,14,16,20-pentaene-4-carboxylic acid
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C38H46O9
 2
1
IC50 = 2238.72 nM
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2
Ki = 1730 nM
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CP0283462
4-[12,18-dihydroxy-8,21,21-trimethyl-5-(3-methylbutyl)-8-(4-methylpentyl)-14-oxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11-tetraen-19-yl]-2-methylbutanoic acid
   Show/Hide
C38H54O8
 2
1
IC50 = 2290.87 nM
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2
Ki = 1770 nM
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CP0083586
methyl 8,10-dichloro-3,9-dihydroxy-1,4,7-trimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylate
   Show/Hide
C18H14Cl2O7
 2
1
IC50 = 2398.83 nM
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2
Ki = 1840 nM
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CP0024953
2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-benzoimidazole-4-carboxylic acid 1-cyclohexyloxycarbonyloxy-ethyl ester
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C33H34N6O6
 2
1
IC50 = 2454.71 nM
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2
Ki = 1900 nM
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CP0161979
methyl 8,10-dichloro-9-hydroxy-3-methoxy-1,7-dimethyl-6-oxobenzo[b][1,4]benzodioxepine-2-carboxylate
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C18H14Cl2O7
 2
1
IC50 = 2630.27 nM
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2
Ki = 2020 nM
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CP0381174
(Z)-4-[(1S,2S,8R,17S,19S)-12,18-dihydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14-oxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11-tetraen-19-yl]-2-methylbut-2-enoic acid
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C38H48O8
 2
1
IC50 = 2818.38 nM
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2
Ki = 2160 nM
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CP0280690
(Z)-4-[12,18-dihydroxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14-oxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4(13),5,9,11,15-pentaen-19-yl]-2-methylbut-2-enoic acid
   Show/Hide
C38H46O8
 2
1
IC50 = 2884.03 nM
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2
Ki = 2240 nM
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CP0355438
BETA CAROTENE
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C40H56
 2
1
IC50 = 2951.21 nM
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2
Ki = 2260 nM
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CP0381198
[(1R,2R,4S,7R,8R,11R,12S,13S,15R,17S,19R)-13-acetyloxy-7-(furan-3-yl)-19-hydroxy-1,8,12,16,16-pentamethyl-5-oxo-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadecan-15-yl] acetate
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C30H40O9
 2
1
IC50 = 2951.21 nM
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2
Ki = 2270 nM
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CP0426731
(1S,2R,4S,7S,8S,11R,12R,13R,15R,18R,20R)-7-(furan-3-yl)-20-hydroxy-1,8,12,17,17-pentamethyl-3,6,14-trioxahexacyclo[9.9.0.02,4.02,8.012,18.013,15]icosane-5,16-dione
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C26H32O7
 1
1
IC50 = 2951.21 nM
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CP0423162
Erythromycin Estolate
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C52H97NO18S
 2
1
IC50 = 3090.3 nM
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2
Ki = 2350 nM
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CP0391194
beta-DIHYDROGEDUNOL
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C28H38O7
 1
1
IC50 = 3235.94 nM
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CP0133264
A-56268
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C38H69NO13
 1
1
IC50 = 3311.31 nM
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CP0429602
(1S,4bS,5R,6aS,10aS,10bS,12aS)-1-(furan-3-yl)-5-hydroxy-4b,7,7,10a,12a-pentamethyl-5,6,6a,9,10,10b,11,12-octahydro-1H-naphtho[2,1-f]isochromene-3,8-dione
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C26H34O5
 2
1
IC50 = 3311.31 nM
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2
Ki = 2550 nM
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CP0113897
BILIRUBIN
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C33H36N4O6
 2
1
IC50 = 3388.44 nM
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2
Ki = 2630 nM
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CP0198648
Beta-Escin
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C54H84O24
 2
1
IC50 = 3388.44 nM
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2
Ki = 2610 nM
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CP0391202
PRIEURIANIN
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C37H48O16
 2
1
IC50 = 3388.44 nM
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2
Ki = 2630 nM
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CP0391204
Atorvastatin
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C66H68CaF2N4O10
 2
1
IC50 = 3388.44 nM
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2
Ki = 2580 nM
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CP0877478
ANTHOTHECOL
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C28H32O7
 2
1
IC50 = 3467.37 nM
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2
Ki = 2640 nM
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CP0059405
CHOLIC ACID, METHYL ESTER
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C25H42O5
 2
1
IC50 = 3715.35 nM
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2
Ki = 2890 nM
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CP0109019
Conceptrol
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C33H60O10
 2
1
IC50 = 3715.35 nM
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2
Ki = 2870 nM
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CP0381175
[(1S,4bS,5R,6aS,8R,10aR,10bS,12aS)-1-(furan-3-yl)-8-hydroxy-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,10b,11,12-octahydronaphtho[2,1-f]isochromen-5-yl] acetate
   Show/Hide
C28H36O6
 2
1
IC50 = 3715.35 nM
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2
Ki = 2890 nM
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CP0433071
METHYL 6-ACETOXYANGOLENSATE
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C29H36O9
 2
1
IC50 = 3801.89 nM
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2
Ki = 2920 nM
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CP0435006
[(1S,4bS,5R,6aS,10aS,10bS,12aS)-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3,8-dioxo-5,6,6a,10b,11,12-hexahydro-1H-naphtho[2,1-f]isochromen-5-yl] acetate
   Show/Hide
C28H34O6
 2
1
IC50 = 3801.89 nM
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2
Ki = 2890 nM
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CP0012708
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
   Show/Hide
C15H10O5
 2
1
IC50 = 3890.45 nM
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2
Ki = 2960 nM
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CP0514201
[(1S,2R,4S,7S,8S,10R,11R,12S,13S,15R,17S,19R)-10,13,15-triacetyloxy-7-(furan-3-yl)-1,8,12,16,16-pentamethyl-5-oxo-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadecan-19-yl] acetate
   Show/Hide
C34H44O12
 2
1
IC50 = 3981.07 nM
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2
Ki = 3050 nM
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CP0042741
AURIN
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C19H14O3
 2
1
IC50 = 4073.8 nM
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2
Ki = 3150 nM
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CP0070921
MLS001335996
   Show/Hide
C76H52O46
 2
1
IC50 = 4168.69 nM
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2
Ki = 3230 nM
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CP0645768
SID855643
   Show/Hide
C25H22O10
 2
1
IC50 = 4265.8 nM
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2
Ki = 3270 nM
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CP0074965
(-)-Epicatechin-3-gallate
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C22H18O10
 2
1
IC50 = 4466.84 nM
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2
Ki = 3460 nM
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CP0388301
[(2R,3R)-2-[1-[(2R,3R)-5,7-dihydroxy-3-(3,4,5-trihydroxybenzoyl)oxy-3,4-dihydro-2H-chromen-2-yl]-3,4,6-trihydroxy-5-oxobenzo[7]annulen-8-yl]-5,7-dihydroxy-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
   Show/Hide
C43H32O20
 2
1
IC50 = 4466.84 nM
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2
Ki = 3420 nM
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CP0391201
methyl 2-[(1S,3S,5S,7S,8S,9R,12S,13S)-5-acetyloxy-13-(furan-3-yl)-6,6,8,12-tetramethyl-17-methylidene-15-oxo-2,14-dioxatetracyclo[7.7.1.01,12.03,8]heptadecan-7-yl]acetate
   Show/Hide
C29H38O8
 2
1
IC50 = 4466.84 nM
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2
Ki = 3470 nM
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CP0038508
7-[8-formyl-1,6,7-trihydroxy-3-methyl-5-(propan-2-yl)naphthalen-2-yl]-2,3,8-trihydroxy-6-methyl-4-(propan-2-yl)naphthalene-1-carbaldehyde
   Show/Hide
C30H30O8
 2
1
IC50 = 4570.88 nM
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2
Ki = 3470 nM
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CP0049972
RETINYL ACETATE
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C22H32O2
 2
1
IC50 = 5011.87 nM
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2
Ki = 3890 nM
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CP0381172
(1R,2R,4S,7S,8S,11R,12S,15S,17R)-7-(furan-3-yl)-15-hydroxy-1,8,12,16,16-pentamethyl-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-ene-5,19-dione
   Show/Hide
C26H32O6
 2
1
IC50 = 5011.87 nM
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2
Ki = 3810 nM
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CP0066372
methyl (Z)-4-[12-methoxy-8,21,21-trimethyl-5-(3-methylbut-2-enyl)-8-(4-methylpent-3-enyl)-14,18-dioxo-3,7,20-trioxahexacyclo[15.4.1.02,15.02,19.04,13.06,11]docosa-4,6(11),9,12,15-pentaen-19-yl]-2-methylbut-2-enoate
   Show/Hide
C40H48O8
 2
1
IC50 = 5128.61 nM
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2
Ki = 3940 nM
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CP0137277
Abietic Acid
   Show/Hide
C20H30O2
 2
1
IC50 = 5248.07 nM
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2
Ki = 4080 nM
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CP0433070
[(2R,3R,4S,5R)-3-[(2R,3R,4S,5R,6S)-5-[(2S,3R,4S,5R)-3,5-dihydroxy-4-[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,4-dihydroxy-6-methyloxan-2-yl]oxy-4,5-dihydroxyoxan-2-yl] (4aR,5R,6aR,6aS,6bR,8aR,10S,12aR,14bR)-5-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-10-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylate
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C58H94O25
 2
1
IC50 = 5248.07 nM
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2
Ki = 4020 nM
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CP0433021
Acetyl Isogambogic Acid
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C40H46O9
 2
1
IC50 = 5370.32 nM
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2
Ki = 4170 nM
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CP0019370
Ketek
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C43H65N5O10
 1
1
IC50 = 5888.44 nM
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CP0014077
2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
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C15H22O3
 1
1
IC50 = 7079.46 nM
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CP0423173
[(1R,4bR,5R,6aR,10aR,10bR,12aR)-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3,8-dioxo-5,6,6a,9,10,10b,11,12-octahydro-1H-naphtho[2,1-f]isochromen-5-yl] acetate
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C28H36O6
 2
1
IC50 = 7762.47 nM
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2
Ki = 5990 nM
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CP0461909
[(2R,3R)-5,7-dihydroxy-2-[3,4,5-trihydroxy-2-[2,3,4-trihydroxy-6-[(2R,3R)-3,5,7-trihydroxy-3,4-dihydro-2H-chromen-2-yl]phenyl]phenyl]-3,4-dihydro-2H-chromen-3-yl] 3,4,5-trihydroxybenzoate
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C37H30O18
 2
1
IC50 = 8511.38 nM
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2
Ki = 6500 nM
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CP0040077
(3beta)-3-hydroxyurs-12-en-28-oic acid
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C30H48O3
 1
1
IC50 = 11481.54 nM
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CP0423164
3-acetyl-11-keto-ursolic acid
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C32H48O5
 1
1
IC50 = 11481.54 nM
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CP0054979
DIGOXIN
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C41H64O14
 1
1
IC50 = 13182.57 nM
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CP0423160
Oligomycin
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C45H74O11
 1
1
Ki = 440 nM
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CP0385369
[(1S,4bS,5R,8S,10aR,12aS)-5-acetyloxy-1-(furan-3-yl)-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-8-yl] acetate
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C30H40O7
 1
1
Ki = 2670 nM
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CP0433020
Lorglumide Sodium
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C22H31Cl2N2NaO4
 1
1
Ki = 2710 nM
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CP0432848
methyl 2-[(1S,3S,5S,7S,8S,9R,12S,13S)-13-(furan-3-yl)-5-hydroxy-6,6,8,12-tetramethyl-17-methylidene-15-oxo-2,14-dioxatetracyclo[7.7.1.01,12.03,8]heptadecan-7-yl]acetate
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C27H36O7
 1
1
Ki = 3060 nM
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CP0433031
Salinomycin Sodium
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C42H69NaO11
 1
1
Ki = 3310 nM
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CP0021823
(2R,3S,6S,7R,8R)-3-[(3-formamido-2-hydroxybenzoyl)amino]-8-hexyl-2,6-dimethyl-4,9-dioxo-1,5-dioxonan-7-yl 3-methylbutanoate
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C28H40N2O9
 1
1
Ki = 3820 nM
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CP0391197
[(1S,4bS,5R,8R,10S,10aR,12aR)-1-(furan-3-yl)-8,10-dihydroxy-4b,7,7,10a,12a-pentamethyl-3-oxo-1,5,6,6a,8,9,10,10b,11,12-decahydronaphtho[2,1-f]isochromen-5-yl] acetate
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C28H38O7
 1
1
Ki = 6590 nM
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