| Compound ID |
Compound Name |
Compound Formula |
|
CP0140442
|
(+)-2-Amino-3-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C8H10FNO4
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
Ki = 65.9 nM
|
|
|
|
CP0374563
|
(+)-2-Amino-6-fluoro-4-oxo-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C8H8FNO5
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
Ki = 3.62 nM
|
|
|
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CP0409272
|
(+)-2-Amino-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C8H10FNO4
|
2
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
Ki = 41.7 nM
|
|
|
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CP0211752
|
(1R,2R,3R,5R,6R)-2-Amino-3-(3,4-dichloro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C15H14Cl2FNO5
|
3
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 24 nM
|
|
|
| 3 |
Ki = 4.46 nM
|
|
|
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CP0377729
|
(1S,2S)-2-((S)-1-amino-1-carboxy-2-(9H-xanthen-9-yl)ethyl)cyclopropanecarboxylic acid
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|
C20H19NO5
|
3
|
| 1 |
EC50 > 100000 nM
|
|
|
| 2 |
IC50 = 14.2 nM
|
|
|
| 3 |
Ki = 3.04 nM
|
|
|
|
CP0232347
|
7-ethoxy-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C24H20F3N3O2
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0338876
|
7-ethoxy-4-(3-(pyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C23H18F3N3O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0202837
|
4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C24H20F3N3O
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0053384
|
7-methyl-4-(3-(2-methylpyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C23H18F3N3O
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0484073
|
8-(4-fluorophenyl)-4-(3-imidazol-1-ylphenyl)-1,3-dihydro-1,5-benzodiazepin-2-one
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|
C24H17FN4O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0295954
|
4-(3-(2-methylpyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C22H16F3N3O
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0237670
|
4-(3-(pyridin-4-yl)phenyl)-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C21H14F3N3O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0231490
|
7,8-dichloro-4-(3-(2-methylpyridin-4-yl)phenyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C21H15Cl2N3O
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0059417
|
8-(2-fluorophenyl)-4-(3-imidazol-1-ylphenyl)-1,3-dihydro-1,5-benzodiazepin-2-one
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|
C24H17FN4O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0162027
|
4-(3-(1H-1,2,3-triazol-1-yl)phenyl)-8-(2-fluorophenyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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|
C23H16FN5O
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
IC50 = 42 nM
|
|
|
|
CP0205609
|
8-(2-fluorophenyl)-7-hydroxy-4-(3-imidazol-1-ylphenyl)-1,3-dihydro-1,5-benzodiazepin-2-one
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|
C24H17FN4O2
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0392388
|
(1R,2R,3R,5R,6R)-2-Amino-3-(3,4-difluoro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C15H14F3NO5
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0391913
|
(1R,2R,3R,5R,6R)-2-Amino-3-benzhydryloxy-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C21H20FNO5
|
1
|
| 1 |
Ki = 3.93 nM
|
|
|
|
CP0399772
|
2-[1-Amino-1-carboxy-2-(9H-xanthen-9-yl)-ethyl]-cyclopropanecarboxylic acid
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|
C20H19NO5
|
1
|
| 1 |
Ki = 4.11 nM
|
|
|
|
CP0406578
|
(1R,2R,3R,5R,6R)-2-Amino-3-(4-chloro-benzyloxy)-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C15H15ClFNO5
|
1
|
| 1 |
Ki = 4.77 nM
|
|
|
|
CP0499045
|
(1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-(naphthalen-2-ylmethoxy)-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C19H18FNO5
|
1
|
| 1 |
Ki = 5.43 nM
|
|
|
|
CP0491988
|
(1R,2R,3R,5R,6R)-2-Amino-3-benzyloxy-6-fluoro-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C15H16FNO5
|
1
|
| 1 |
Ki = 15.9 nM
|
|
|
|
CP0076675
|
(1S,2S,5R,6S)-2-Amino-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C8H11NO4
|
1
|
| 1 |
Ki = 53.5 nM
|
|
|
|
CP0497432
|
(1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-hydroxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C8H10FNO5
|
1
|
| 1 |
Ki = 67.1 nM
|
|
|
|
CP0491986
|
(1R,2R,3R,5R,6R)-2-Amino-6-fluoro-3-methoxy-bicyclo[3.1.0]hexane-2,6-dicarboxylic acid
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|
C9H12FNO5
|
1
|
| 1 |
Ki = 88.1 nM
|
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