Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-(2,6-dimethylpyridin-4-yl)phenyl)-7-methyl-8-(trifluoromethyl)-1H-benzo[b][1,4]diazepin-2(3H)-one
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 PubChem ID
CID: 11158623
SID: 16393244
Canonical SMILES
Cc1cc(cc(C)n1)-c1cccc(c1)C1=Nc2cc(C)c(cc2NC(=O)C1)C(F)(F)F
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Compound Formula C24H20F3N3O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 3
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31422
Gene Name
GRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 < 10 nM
   TI
   LI
   LO
   TS