| Compound ID |
Compound Name |
Compound Formula |
|
CP0459534
|
1-(3-fluoro-4-(4-(5-nitro-2-(piperidin-1-yl)benzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C24H27FN4O4
|
1
|
| 1 |
EC50 = 1 nM
|
|
|
|
CP0459633
|
1-(4-(4-(2-(cyclohexylamino)-5-nitrobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C25H29FN4O4
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0474948
|
1-(3-fluoro-4-(4-(2-(isopropylamino)-5-nitrobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C22H25FN4O4
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0372392
|
4-[4-(2-Cyclohexyloxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C25H28FN3O4S
|
1
|
| 1 |
EC50 = 8 nM
|
|
|
|
CP0377260
|
1-(4-(4-(2-sec-butoxy-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C24H29FN2O5S
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0452144
|
3-Fluoro-4-[4-(2-isobutoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C23H26FN3O4S
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0452616
|
3-fluoro-4-(4-(5-(methylsulfonyl)-2-(piperidin-1-yl)benzoyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C24H27FN4O3S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0405579
|
4-[4-(2-Cyclopentyloxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C24H26FN3O4S
|
1
|
| 1 |
EC50 = 12 nM
|
|
|
|
CP0425937
|
[4-[2-fluoro-4-(trifluoromethyl)phenyl]piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H21F7N2O4S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0421272
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-phenylisoindolin-2-yl)methanone
Show/Hide
|
C25H22F3NO4S
|
1
|
| 1 |
EC50 = 13 nM
|
|
|
|
CP0522107
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(tetrahydro-2H-pyran-4-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H26F3NO5S
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0459632
|
1-(3-fluoro-4-(4-(2-morpholino-5-nitrobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C23H25FN4O5
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0489989
|
2-(4-(2-morpholino-5-nitrobenzoyl)piperazin-1-yl)-5-(trifluoromethyl)benzonitrile
Show/Hide
|
C23H22F3N5O4
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0508191
|
1-(3-fluoro-4-(4-(2-(isopropylthio)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C23H27FN2O4S2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0522858
|
1-(4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C24H27FN2O5S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0048052
|
4-(4-(2-(cyclopropylmethoxy)-5-(methylsulfonyl)benzoyl)piperazin-1-yl)-3-fluorobenzonitrile
Show/Hide
|
C23H24FN3O4S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0377261
|
1-(3-fluoro-4-(4-(3'-fluoro-4-(methylsulfonyl)biphenylcarbonyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C26H24F2N2O4S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0478731
|
(4'-fluoro-4-(methylsulfonyl)biphenyl-2-yl)(5-(tetrahydro-2H-pyran-4-yl)isoindolin-2-yl)methanone
Show/Hide
|
C27H26FNO4S
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0478726
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(pyridin-4-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H21F3N2O4S
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
|
CP0411825
|
4-[4-(2-Cyclobutoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C23H24FN3O4S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
|
CP0522857
|
3-fluoro-4-(4-(4-(methylsulfonyl)biphenylcarbonyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C25H22FN3O3S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0425944
|
4-[4-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C22H22F3N3O4S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0527694
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(trifluoromethyl)isoindolin-2-yl)methanone
Show/Hide
|
C20H17F6NO4S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0502200
|
(2-cyclohexyl-5-(methylsulfonyl)phenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C25H29F3N2O3S
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0452145
|
3-Fluoro-4-{4-[5-methanesulfonyl-2-(2,2,2-trifluoro-ethoxy)-benzoyl]-piperazin-1-yl}-benzonitrile
Show/Hide
|
C21H19F4N3O4S
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0421271
|
(2-isopropoxy-5-(methylsulfonyl)phenyl)(5-(tetrahydro-2H-pyran-4-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H29NO5S
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0529003
|
(4'-fluoro-4-(methylsulfonyl)biphenyl-2-yl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C25H22F4N2O3S
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
|
CP0455119
|
3-fluoro-4-(4-(2-morpholino-5-nitrobenzoyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C22H22FN5O4
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0093117
|
[2-[(2S)-3,3-dimethylbutan-2-yl]oxy-5-methylsulfonylphenyl]-[4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C24H29F4N3O4S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0401874
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]methanone
Show/Hide
|
C22H22F6N2O4S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0425932
|
[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C21H20ClF6N3O4S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0376457
|
(2-isobutoxy-5-(methylsulfonyl)phenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C20H21F3N2O4S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0380206
|
(3',4'-difluoro-4-(methylsulfonyl)biphenyl-2-yl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C22H15F5N2O3S
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0455114
|
(4-(methylsulfonyl)biphenyl-2-yl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C25H23F3N2O3S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0459653
|
(4-(6-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C21H21ClF3N5O4
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0471044
|
3-Fluoro-4-[4-(5-methanesulfonyl-2-propoxy-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C22H24FN3O4S
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0489988
|
(4-(3-fluoro-4-(trifluoromethyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H22F4N4O4
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0401887
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C21H21F6N3O4S
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0510101
|
1-(3-fluoro-4-(4-(2-isopropoxy-5-(methylsulfonyl)benzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C23H27FN2O5S
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0377262
|
(4-(2-fluoro-4-(methylsulfonyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H25FN4O6S
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0514681
|
(2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C23H25F3N2O4S
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0844912
|
rac-4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl]-[5-methanesulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)phenyl]-methanone
Show/Hide
|
C21H20F7N3O4S
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0459637
|
(4-(2-fluoro-4-(trifluoromethyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H22F4N4O4
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0471043
|
3-fluoro-4-[4-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl]piperazin-1-yl]benzonitrile
Show/Hide
|
C22H21F4N3O4S
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0459536
|
(5-(methylsulfonyl)-2-morpholinophenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C23H26F3N3O4S
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0459654
|
(4-(2-fluoro-4-(methylsulfonyl)phenyl)piperazin-1-yl)(5-(methylsulfonyl)-2-(piperidin-1-yl)phenyl)methanone
Show/Hide
|
C24H30FN3O5S2
|
1
|
| 1 |
EC50 = 46 nM
|
|
|
|
CP0502193
|
(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C21H21ClF3N5O4
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0439483
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C19H16F6N2O4S
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0498051
|
(2-(cyclopropylmethoxy)-5-(methylsulfonyl)phenyl)(4-(2-fluoro-4-(methylsulfonyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C23H27FN2O6S2
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0459624
|
(4-(2-fluoro-4-(methylsulfonyl)phenyl)piperazin-1-yl)(4-(methylsulfonyl)biphenyl-2-yl)methanone
Show/Hide
|
C25H25FN2O5S2
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0486889
|
[2-[(2R)-3,3-dimethylbutan-2-yl]oxy-5-methylsulfonylphenyl]-[4-[3-fluoro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C24H29F4N3O4S
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0498053
|
1-(3-fluoro-4-(4-(4-(methylsulfonyl)biphenylcarbonyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C26H25FN2O4S
|
1
|
| 1 |
EC50 = 69 nM
|
|
|
|
CP0152495
|
1-(3-fluoro-4-(4-(5-(methylsulfonyl)-2-morpholinobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C24H28FN3O5S
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0471006
|
3-Fluoro-4-[4-(2-isopropoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C22H24FN3O4S
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0501876
|
(2-isopropoxy-5-(methylsulfonyl)phenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C19H19F3N2O4S
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0502194
|
(5-(methylsulfonyl)-2-(piperidin-1-yl)phenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C24H28F3N3O3S
|
1
|
| 1 |
EC50 = 75 nM
|
|
|
|
CP0459631
|
4-(4-(2-morpholino-5-nitrobenzoyl)piperazin-1-yl)benzonitrile
Show/Hide
|
C22H23N5O4
|
1
|
| 1 |
EC50 = 78 nM
|
|
|
|
CP0425939
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[3-methyl-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C22H23F6N3O4S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0504339
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[6-(trifluoromethyl)pyridin-3-yl]piperazin-1-yl]methanone
Show/Hide
|
C21H21F6N3O4S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0459625
|
(2-isopropoxy-5-(methylsulfonyl)phenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H25F3N2O4S
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
|
CP0501875
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(pyridin-2-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H21F3N2O4S
|
1
|
| 1 |
EC50 = 84 nM
|
|
|
|
CP0388322
|
1-[4-[4-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl]piperazin-1-yl]phenyl]ethanone
Show/Hide
|
C23H25F3N2O5S
|
1
|
| 1 |
EC50 = 91 nM
|
|
|
|
CP0388174
|
(2-morpholino-5-nitrophenyl)(4-(4-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23F3N4O4
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0526594
|
3-(4-(4-acetyl-2-fluorophenyl)piperazine-1-carbonyl)-N-methyl-4-morpholinobenzenesulfonamide
Show/Hide
|
C24H29FN4O5S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0438721
|
[4-(4-methylsulfonylphenyl)piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H25F3N2O6S2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0438725
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyrimidin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C20H20F6N4O4S
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0481517
|
(4-(4-(methylsulfonyl)phenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H26N4O6S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0504367
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[5-(trifluoromethyl)pyrazin-2-yl]piperazin-1-yl]methanone
Show/Hide
|
C20H20F6N4O4S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0379523
|
(5-(methylsulfonyl)-2-(3,3,3-trifluoropropoxy)phenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C19H16F6N2O4S
|
1
|
| 1 |
EC50 = 111 nM
|
|
|
|
CP0459626
|
3-(4-(4-acetyl-2-fluorophenyl)piperazine-1-carbonyl)-4-morpholinobenzenesulfonamide
Show/Hide
|
C23H27FN4O5S
|
1
|
| 1 |
EC50 = 120 nM
|
|
|
|
CP0412907
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(6-(trifluoromethyl)-1H-pyrrolo[3,4-c]pyridin-2(3H)-yl)methanone
Show/Hide
|
C19H16F6N2O4S
|
1
|
| 1 |
EC50 = 132 nM
|
|
|
|
CP0497005
|
(5-(methylsulfonyl)-2-(3,3,3-trifluoropropoxy)phenyl)(5-(tetrahydro-2H-pyran-4-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H26F3NO5S
|
1
|
| 1 |
EC50 = 137 nM
|
|
|
|
CP0459628
|
3-(4-(4-acetyl-2-fluorophenyl)piperazine-1-carbonyl)-4-morpholinobenzonitrile
Show/Hide
|
C24H25FN4O3
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0412912
|
(S)-(5-methoxyisoindolin-2-yl)(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)methanone
Show/Hide
|
C20H20F3NO5S
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0439524
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(pyrrolidin-1-yl)isoindolin-2-yl)methanone
Show/Hide
|
C23H25F3N2O4S
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0469902
|
[4-[2-chloro-4-(trifluoromethyl)phenyl]piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H21ClF6N2O4S
|
1
|
| 1 |
EC50 = 200 nM
|
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|
CP0478725
|
(5-(methylsulfonyl)-2-((S)-1,1,1-trifluoropropan-2-yloxy)phenyl)(5-(tetrahydro-2H-pyran-2-yl)isoindolin-2-yl)methanone
Show/Hide
|
C24H26F3NO5S
|
1
|
| 1 |
EC50 = 205 nM
|
|
|
|
CP0478727
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(2-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C19H16F6N2O4S
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0412909
|
(S)-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)(5-morpholinoisoindolin-2-yl)methanone
Show/Hide
|
C23H25F3N2O5S
|
1
|
| 1 |
EC50 = 275 nM
|
|
|
|
CP0459629
|
(4-(4-chlorophenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C21H23ClN4O4
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0388321
|
[4-(4-methylphenyl)piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H25F3N2O4S
|
1
|
| 1 |
EC50 = 310 nM
|
|
|
|
CP0405575
|
4-[4-(2-Cyclohexylmethoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C26H30FN3O4S
|
1
|
| 1 |
EC50 = 390 nM
|
|
|
|
CP0498052
|
(2-morpholino-5-nitrophenyl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23F3N4O4
|
1
|
| 1 |
EC50 = 400 nM
|
|
|
|
CP0471045
|
[4-(4-methoxyphenyl)piperazin-1-yl]-[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]methanone
Show/Hide
|
C22H25F3N2O5S
|
1
|
| 1 |
EC50 = 430 nM
|
|
|
|
CP0424076
|
1-(4-(4-(2-(dimethylamino)-5-nitrobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C21H23FN4O4
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0405577
|
3-Fluoro-4-{4-[5-methanesulfonyl-2-(tetrahydro-pyran-4-yloxy)-benzoyl]-piperazin-1-yl}-benzonitrile
Show/Hide
|
C24H26FN3O5S
|
1
|
| 1 |
EC50 = 500 nM
|
|
|
|
CP0455120
|
(4-(3-methoxyphenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H26N4O5
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0425945
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[2-(trifluoromethyl)pyrimidin-5-yl]piperazin-1-yl]methanone
Show/Hide
|
C20H20F6N4O4S
|
1
|
| 1 |
EC50 = 530 nM
|
|
|
|
CP0471042
|
4-[4-(2-Ethoxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C21H22FN3O4S
|
1
|
| 1 |
EC50 = 590 nM
|
|
|
|
CP0481298
|
(4-(3-chlorophenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C21H23ClN4O4
|
1
|
| 1 |
EC50 = 700 nM
|
|
|
|
CP0478729
|
(S)-2-(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)benzoyl)isoindoline-4-carbonitrile
Show/Hide
|
C20H17F3N2O4S
|
1
|
| 1 |
EC50 = 770 nM
|
|
|
|
CP0478732
|
(2-(benzyloxy)-5-(methylsulfonyl)phenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C23H19F3N2O4S
|
1
|
| 1 |
EC50 = 805 nM
|
|
|
|
CP0438722
|
[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[4-[6-(trifluoromethyl)pyridazin-3-yl]piperazin-1-yl]methanone
Show/Hide
|
C20H20F6N4O4S
|
1
|
| 1 |
EC50 = 900 nM
|
|
|
|
CP0424074
|
(2-morpholino-5-nitrophenyl)(4-m-tolylpiperazin-1-yl)methanone
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
EC50 = 1100 nM
|
|
|
|
CP0481299
|
(4-(4-methoxyphenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H26N4O5
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0455115
|
(4-(2-chlorophenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C21H23ClN4O4
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0431373
|
1-(3-fluoro-4-(4-(2-morpholino-5-(propylsulfonyl)benzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C26H32FN3O5S
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0405576
|
4-[4-(2-Benzyloxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-3-fluoro-benzonitrile
Show/Hide
|
C26H24FN3O4S
|
1
|
| 1 |
EC50 = 1610 nM
|
|
|
|
CP0439595
|
1-(3-fluoro-4-(4-(2-(methylamino)-5-nitrobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C20H21FN4O4
|
1
|
| 1 |
EC50 = 1900 nM
|
|
|
|
CP0421270
|
(S)-(4-methoxyisoindolin-2-yl)(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)methanone
Show/Hide
|
C20H20F3NO5S
|
1
|
| 1 |
EC50 = 1940 nM
|
|
|
|
CP0478734
|
(S)-(5-(4-methylpiperazin-1-yl)isoindolin-2-yl)(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)methanone
Show/Hide
|
C24H28F3N3O4S
|
1
|
| 1 |
EC50 = 2080 nM
|
|
|
|
CP0478736
|
(S)-isoindolin-2-yl(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)methanone
Show/Hide
|
C19H18F3NO4S
|
1
|
| 1 |
EC50 = 2540 nM
|
|
|
|
CP0474950
|
(2-morpholino-5-nitrophenyl)(4-p-tolylpiperazin-1-yl)methanone
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
EC50 = 2900 nM
|
|
|
|
CP0478730
|
(5-(methylsulfonyl)-2-morpholinophenyl)(3-(trifluoromethyl)-5H-pyrrolo[3,4-b]pyridin-6(7H)-yl)methanone
Show/Hide
|
C20H20F3N3O4S
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0380208
|
(S)-(4-methylisoindolin-2-yl)(5-(methylsulfonyl)-2-(1,1,1-trifluoropropan-2-yloxy)phenyl)methanone
Show/Hide
|
C20H20F3NO4S
|
1
|
| 1 |
EC50 = 3360 nM
|
|
|
|
CP0424075
|
(2-morpholino-5-nitrophenyl)(4-(2-(trifluoromethyl)phenyl)piperazin-1-yl)methanone
Show/Hide
|
C22H23F3N4O4
|
1
|
| 1 |
EC50 = 7100 nM
|
|
|
|
CP0405574
|
3-Fluoro-4-[4-(5-methanesulfonyl-2-methoxy-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C20H20FN3O4S
|
1
|
| 1 |
EC50 = 9800 nM
|
|
|
|
CP0455117
|
(4-(2-methoxyphenyl)piperazin-1-yl)(2-morpholino-5-nitrophenyl)methanone
Show/Hide
|
C22H26N4O5
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0455118
|
(2-morpholino-5-nitrophenyl)(4-o-tolylpiperazin-1-yl)methanone
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0474949
|
1-(4-(4-(2-amino-5-nitrobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C19H19FN4O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0489990
|
1-(4-(4-(2-(cyclohexylmethylamino)-5-nitrobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C26H31FN4O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0388320
|
4-{4-[2-(2-Dimethylamino-ethoxy)-5-methanesulfonyl-benzoyl]-piperazin-1-yl}-3-fluorobenzonitrile
Show/Hide
|
C23H27FN4O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0425935
|
3-Fluoro-4-[4-(2-hydroxy-5-methanesulfonyl-benzoyl)-piperazin-1-yl]-benzonitrile
Show/Hide
|
C19H18FN3O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0459634
|
1-(3-fluoro-4-(4-(2-morpholino-5-(trifluoromethyl)benzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C24H25F4N3O3
|
1
|
| 1 |
EC50 = 26000 nM
|
|
|
|
CP0377263
|
1-(3-fluoro-4-(4-(2-morpholinobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C23H26FN3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0441239
|
1-(4-(4-(5-amino-2-morpholinobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C23H27FN4O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0441240
|
1-(4-(4-(5-bromo-2-morpholinobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C23H25BrFN3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0459630
|
1-(3-fluoro-4-(4-(5-methyl-2-morpholinobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C24H28FN3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0508190
|
1-(4-(4-(5-(benzylsulfonyl)-2-morpholinobenzoyl)piperazin-1-yl)-3-fluorophenyl)ethanone
Show/Hide
|
C30H32FN3O5S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0459635
|
1-(3-fluoro-4-(4-(3-nitrobenzoyl)piperazin-1-yl)phenyl)ethanone
Show/Hide
|
C19H18FN3O4
|
1
|
| 1 |
EC50 = 32000 nM
|
|
|
|
CP0061480
|
2,6-dimethyl-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0410252
|
2,6-dimethyl-N-[phenyl-(7-propan-2-yl-7-azabicyclo[2.2.1]heptan-1-yl)methyl]benzamide
Show/Hide
|
C25H32N2O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0519833
|
N-[[4-(cyclopropylmethylsulfonyl)phenyl]-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-2,6-dimethylbenzamide
Show/Hide
|
C28H36N2O3S
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0526367
|
2,6-dimethyl-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-pyridin-4-ylmethyl]benzamide
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0526368
|
2,6-dimethyl-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-(5-methylfuran-2-yl)methyl]benzamide
Show/Hide
|
C23H30N2O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0536425
|
2,3-dichloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C22H24Cl2N2O
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0526365
|
N-[(7-cyclopropyl-7-azabicyclo[2.2.1]heptan-1-yl)-phenylmethyl]-2,6-dimethylbenzamide
Show/Hide
|
C25H30N2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0305114
|
2-chloro-N-[(S)-[(2S)-1-methylpiperidin-2-yl]-phenylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H22ClF3N2O
|
2
|
| 1 |
IC50 = 2.5 nM
|
|
|
| 2 |
IC50 = 3 nM
|
|
|
|
CP0470509
|
N-[2-azabicyclo[2.2.2]octan-1-yl(phenyl)methyl]-2,6-dimethylbenzamide
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0526364
|
N-[(2-ethyl-2-azabicyclo[2.1.1]hexan-1-yl)-phenylmethyl]-2,6-dimethylbenzamide
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0526366
|
2,6-dimethyl-N-[(7-methyl-7-azabicyclo[2.2.1]heptan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0536424
|
N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]-2-methylsulfanylpyridine-3-carboxamide
Show/Hide
|
C22H27N3OS
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0476005
|
N-[(7-ethyl-7-azabicyclo[2.2.1]heptan-1-yl)-phenylmethyl]-2,6-dimethylbenzamide
Show/Hide
|
C24H30N2O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0476007
|
2,3-dichloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-4-carboxamide
Show/Hide
|
C21H23Cl2N3O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0526370
|
2,6-dimethoxy-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0412394
|
2,6-dimethyl-N-[(2-methyl-2-azabicyclo[2.1.1]hexan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C22H26N2O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0519834
|
2-amino-6-chloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C22H26ClN3O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0470620
|
N-[(3-bromophenyl)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-2-chloro-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H23BrClF3N2O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0451928
|
US9067871, 3
Show/Hide
|
C23H26Cl2N4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0516788
|
US9067871, 4
Show/Hide
|
C23H26Cl2N4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0517473
|
US9067871, 28
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0518253
|
US9067871, 27
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0518848
|
US9067871, 48
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0554649
|
US9067871, 47
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
IC50 < 10 nM
|
|
|
|
CP0477732
|
2,6-dimethyl-N-[(7-propan-2-yl-7-azabicyclo[2.2.1]heptan-1-yl)-pyridin-4-ylmethyl]benzamide
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0568755
|
2-chloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H24ClF3N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0536423
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-pyridin-4-ylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23ClF3N3O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0391887
|
2,6-dichloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]benzamide
Show/Hide
|
C22H24Cl2N2O
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0477733
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-(3-methylphenyl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0391886
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H24ClF3N2O
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0391888
|
2-chloro-N-[(S)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C23H24ClF3N2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0485964
|
N-[7-azabicyclo[2.2.1]heptan-1-yl(pyridin-4-yl)methyl]-2,6-dimethylbenzamide
Show/Hide
|
C21H25N3O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0485979
|
3,5-dichloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-4-carboxamide
Show/Hide
|
C21H23Cl2N3O
|
1
|
| 1 |
IC50 = 45 nM
|
|
|
|
CP0470508
|
N-[7-azabicyclo[2.2.1]heptan-1-yl(phenyl)methyl]-2,6-dimethylbenzamide
Show/Hide
|
C22H26N2O
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0568753
|
3-bromo-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-4-carboxamide
Show/Hide
|
C21H24BrN3O
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0567126
|
2-chloro-N-[furan-2-yl-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H22ClF3N2O2
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0470621
|
3-fluoro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]-2-(trifluoromethyl)pyridine-4-carboxamide
Show/Hide
|
C22H23F4N3O
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0899587
|
Lithium salt of {[3-(4-chloro-phenyl)-3-(4-trifluoromethyl-phenoxy)-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H18ClF3LiNO3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0535908
|
US9067871, 8
Show/Hide
|
C22H28Cl2N2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0535909
|
US9067871, 45
Show/Hide
|
C22H30N2O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0557620
|
US9067871, 55
Show/Hide
|
C22H29ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0557622
|
US9067871, 71
Show/Hide
|
C23H26Cl2N4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0563945
|
BDBM164690
Show/Hide
|
C21H28N2O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0565571
|
US9067871, 44
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0567351
|
US9067871, 18
Show/Hide
|
C25H25Cl2F3N4O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0567352
|
US9067871, 20
Show/Hide
|
C24H26Cl2N4O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390249
|
US8653100, 7
Show/Hide
|
C23H29ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390250
|
US8653100, 12
Show/Hide
|
C22H26ClFN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390251
|
US8653100, 17
Show/Hide
|
C25H27ClN2O3S2
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390253
|
US8653100, 37
Show/Hide
|
C25H29ClN4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390254
|
US8653100, 138
Show/Hide
|
C25H27ClF2N4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0390255
|
US8653100, 49
Show/Hide
|
C24H31ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0402730
|
US8653100, 160
Show/Hide
|
C26H34ClN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0415285
|
US8653100, 4
Show/Hide
|
C24H31ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0450093
|
US8653100, 87
Show/Hide
|
C23H29ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0480756
|
US8653100, 145
Show/Hide
|
C22H29ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0492503
|
US8653100, 85
Show/Hide
|
C25H26ClN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0499834
|
US8653100, 86
Show/Hide
|
C24H27ClN4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0499835
|
US8653100, 103
Show/Hide
|
C25H33ClN2O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0503617
|
US8653100, 14
Show/Hide
|
C26H27ClFN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0527592
|
US8653100, 66
Show/Hide
|
C26H28FN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0535599
|
US8653100, 44
Show/Hide
|
C24H29ClF2N2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0536383
|
US8653100, 67
Show/Hide
|
C26H35ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0536977
|
US8653100, 2
Show/Hide
|
C22H27ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0539336
|
US8653100, 95
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0539707
|
US8653100, 28
Show/Hide
|
C24H29ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0539708
|
US8653100, 65
Show/Hide
|
C24H31FN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0548587
|
US8653100, 76
Show/Hide
|
C25H33ClN2O4S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0550982
|
US8653100, 8
Show/Hide
|
C25H33ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0555338
|
US8653100, 15
Show/Hide
|
C24H30ClFN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0555339
|
US8653100, 16
Show/Hide
|
C25H33ClN2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0555342
|
US8653100, 80
Show/Hide
|
C26H32ClN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0555344
|
US8653100, 142
Show/Hide
|
C24H32ClN3O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0865182
|
US8653100, 50
Show/Hide
|
C24H32N2O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0945265
|
US8653100, 57
Show/Hide
|
C24H27ClN4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0959831
|
US8653100, 51
Show/Hide
|
C25H29ClN4O3S
|
1
|
| 1 |
IC50 < 100 nM
|
|
|
|
CP0657826
|
Lithium salt of {methyl-[(R)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-acetate
Show/Hide
|
C19H19F3LiNO3
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0943218
|
Lithium salt of {[(R)-3-(biphenyl-4-yloxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C24H24LiNO3
|
1
|
| 1 |
IC50 = 151.36 nM
|
|
|
|
CP0526363
|
N-[2-azabicyclo[2.1.1]hexan-1-yl(phenyl)methyl]-2,6-dimethylbenzamide
Show/Hide
|
C21H24N2O
|
1
|
| 1 |
IC50 = 168 nM
|
|
|
|
CP0567128
|
2-chloro-N-[(3-methoxyphenyl)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O2
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0526369
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-pyridin-3-ylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23ClF3N3O
|
1
|
| 1 |
IC50 = 211 nM
|
|
|
|
CP0962725
|
Lithium salt of {[3-(4-fluoro-phenyl)-3-(4-trifluoromethyl-phenoxy)-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H18F4LiNO3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0403675
|
2-chloro-N-[(S)-phenyl-[(2S)-piperidin-2-yl]methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C20H20ClF3N2O
|
1
|
| 1 |
IC50 = 314 nM
|
|
|
|
CP0874357
|
Lithium salt of {methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-acetate
Show/Hide
|
C19H19F3LiNO3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0521608
|
2-chloro-N-[(2-methoxyphenyl)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0875649
|
Lithium salt of {[3-(4-chloro-3-trifluoromethyl-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H18ClF3LiNO3
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0880887
|
Lithium salt of {[(R)-3-(4-tert-butyl-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C22H28LiNO3
|
1
|
| 1 |
IC50 = 446.68 nM
|
|
|
|
CP0568754
|
3-chloro-5-methoxy-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-4-carboxamide
Show/Hide
|
C22H26ClN3O2
|
1
|
| 1 |
IC50 = 474 nM
|
|
|
|
CP0410253
|
2,4-dimethyl-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-3-carboxamide
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
IC50 = 494 nM
|
|
|
|
CP0880872
|
Lithium salt of {[3-(3,4-dichloro-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C18H18Cl2LiNO3
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0947433
|
Lithium salt of {[3-(4-methoxy-phenyl)-3-(4-trifluoromethyl-phenoxy)-propyl]-methyl-amino}-acetate
Show/Hide
|
C20H21F3LiNO4
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0486025
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-(2-methylphenyl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O
|
1
|
| 1 |
IC50 = 514 nM
|
|
|
|
CP0520817
|
2,4-dichloro-N-[(R)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-phenylmethyl]pyridine-3-carboxamide
Show/Hide
|
C21H23Cl2N3O
|
1
|
| 1 |
IC50 = 809 nM
|
|
|
|
CP0476006
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-pyridin-2-ylmethyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C22H23ClF3N3O
|
1
|
| 1 |
IC50 = 904 nM
|
|
|
|
CP0568751
|
2,6-dimethyl-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-[3-(1-methylpyrazol-4-yl)phenyl]methyl]benzamide
Show/Hide
|
C28H34N4O
|
1
|
| 1 |
IC50 = 946 nM
|
|
|
|
CP0871253
|
Lithium salt of {[(S)-3-(biphenyl-4-yloxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C24H24LiNO3
|
1
|
| 1 |
IC50 = 977.24 nM
|
|
|
|
CP0880864
|
Lithium salt of {methyl-[3-phenyl-4-(4-trifluoromethyl-phenyl)-butyl]-amino}-acetate
Show/Hide
|
C20H21F3LiNO2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0895372
|
Lithium salt of {[3-(4-chloro-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C18H19ClLiNO3
|
1
|
| 1 |
IC50 = 1258.93 nM
|
|
|
|
CP0568752
|
2-chloro-N-[(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)-(4-methylphenyl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O
|
1
|
| 1 |
IC50 = 1703 nM
|
|
|
|
CP0391885
|
2-chloro-N-[(4-methoxyphenyl)-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C24H26ClF3N2O2
|
1
|
| 1 |
IC50 = 1759 nM
|
|
|
|
CP0858089
|
Lithium salt of {methyl-[3-phenyl-3-(3-trifluoromethyl-phenoxy)-propyl]-amino}-acetate
Show/Hide
|
C19H19F3LiNO3
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0922715
|
Lithium salt of [methyl-(3-phenyl-3-p-tolyloxy-propyl)-amino]-acetate
Show/Hide
|
C19H22LiNO3
|
1
|
| 1 |
IC50 = 2511.89 nM
|
|
|
|
CP0921852
|
Lithium salt of {methyl-[(S)-3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-acetate
Show/Hide
|
C19H19F3LiNO3
|
1
|
| 1 |
IC50 = 2630.27 nM
|
|
|
|
CP0567127
|
2-chloro-N-[1-(2-methyl-2-azabicyclo[2.2.2]octan-1-yl)pentyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C21H28ClF3N2O
|
1
|
| 1 |
IC50 = 3362 nM
|
|
|
|
CP0914448
|
Lithium salt of {[3-(4-methoxy-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H22LiNO4
|
1
|
| 1 |
IC50 = 3981.07 nM
|
|
|
|
CP0921069
|
Lithium salt of {ethyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-acetate
Show/Hide
|
C20H21F3LiNO3
|
1
|
| 1 |
IC50 = 5011.87 nM
|
|
|
|
CP0915700
|
Lithium salt of {[(S)-3-(4-tert-butyl-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C22H28LiNO3
|
1
|
| 1 |
IC50 = 11748.98 nM
|
|
|
|
CP0918161
|
Lithium salt of {[3-(2-chloro-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C18H19ClLiNO3
|
1
|
| 1 |
IC50 = 12589.25 nM
|
|
|
|
CP0946918
|
Lithium salt of {[3-(2-methoxy-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H22LiNO4
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0520814
|
4-(1-methylimidazol-4-yl)-1,3-thiazole
Show/Hide
|
C7H7N3S
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0860165
|
Lithium salt of 3-{methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-propionate
Show/Hide
|
C20H21F3LiNO3
|
1
|
| 1 |
IC50 = 31622.78 nM
|
|
|
|
CP0930836
|
Lithium salt of {[3-(4-methanesulfonyl-phenoxy)-3-phenyl-propyl]-methyl-amino}-acetate
Show/Hide
|
C19H22LiNO5S
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0932154
|
Lithium salt of 4-{methyl-[3-phenyl-3-(4-trifluoromethyl-phenoxy)-propyl]-amino}-butyrate
Show/Hide
|
C21H23F3LiNO3
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0556446
|
US9067871, 54
Show/Hide
|
C27H31ClN2O5S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0563828
|
US9067871, 60
Show/Hide
|
C28H33ClN2O5S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0564936
|
US9067871, 63
Show/Hide
|
C26H28Cl2N2O5S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0451927
|
US9067871, 2
Show/Hide
|
C26H30Cl2N4O5S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0462650
|
US9067871, 9
Show/Hide
|
C26H30Cl2N4O5S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0462658
|
US9067871, 56
Show/Hide
|
C23H25ClN2O3S2
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0462660
|
US9067871, 80
Show/Hide
|
C26H31ClN4O5S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0466875
|
US9067871, 11
Show/Hide
|
C23H30Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0492536
|
US9067871, 6
Show/Hide
|
C24H32Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0492541
|
US9067871, 77
Show/Hide
|
C23H31ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0518254
|
US9067871, 33
Show/Hide
|
C22H27ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0518255
|
US9067871, 43
Show/Hide
|
C22H28N2O2S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0542224
|
US9067871, 46
Show/Hide
|
C27H35ClN2O5
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0553376
|
US9067871, 5
Show/Hide
|
C24H25Cl2N3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0553378
|
US9067871, 31
Show/Hide
|
C21H27FN2O2S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0556448
|
US9067871, 66
Show/Hide
|
C24H29ClN4O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0557624
|
US9067871, 79
Show/Hide
|
C23H31ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0563223
|
US9067871, 70
Show/Hide
|
C21H27ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0563829
|
US9067871, 82
Show/Hide
|
C11H23NO5S2
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0563943
|
US9067871, 25
Show/Hide
|
C21H27Cl2N3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0564935
|
US9067871, 15
Show/Hide
|
C20H24Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0565652
|
US9067871, 67
Show/Hide
|
C24H27ClN2O3S2
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0390252
|
US8653100, 18
Show/Hide
|
C28H31ClN2O4S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0390256
|
US8653100, 58
Show/Hide
|
C33H35ClN4O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0441556
|
US8653100, 69
Show/Hide
|
C27H38ClN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0441557
|
US8653100, 77
Show/Hide
|
C26H32ClN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0506886
|
US8653100, 25
Show/Hide
|
C27H28Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0508983
|
US8653100, 13
Show/Hide
|
C27H28ClFN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0508984
|
US8653100, 31
Show/Hide
|
C28H31ClN2O4S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0508985
|
US8653100, 35
Show/Hide
|
C26H31ClN4O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0527593
|
US8653100, 72
Show/Hide
|
C25H33FN4O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0539546
|
US8653100, 73
Show/Hide
|
C24H30BrFN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0539547
|
US8653100, 101
Show/Hide
|
C26H28FN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0548588
|
US8653100, 82
Show/Hide
|
C25H33ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0555340
|
US8653100, 29
Show/Hide
|
C26H27Cl2N3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0556515
|
US8653100, 62
Show/Hide
|
C27H29ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0556516
|
US8653100, 75
Show/Hide
|
C24H32FN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560559
|
US8653100, 27
Show/Hide
|
C27H28Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560561
|
US8653100, 46
Show/Hide
|
C26H32ClN5O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560680
|
US8653100, 26
Show/Hide
|
C27H28Cl2N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560684
|
US8653100, 30
Show/Hide
|
C30H30ClN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560685
|
US8653100, 40
Show/Hide
|
C26H35ClN2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0560686
|
US8653100, 45
Show/Hide
|
C29H42ClN3O5S2
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0563050
|
US8653100, 24
Show/Hide
|
C28H28ClN3O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0570465
|
US8653100, 71
Show/Hide
|
C26H32F4N2O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0957324
|
US8653100, 79
Show/Hide
|
C27H33FN4O3S
|
1
|
| 1 |
IC50 < 1000 nM
|
|
|
|
CP0459869
|
US9067871, 59
Show/Hide
|
C23H24Cl2N2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0459870
|
US9067871, 84
Show/Hide
|
C22H28ClNO3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0462659
|
US9067871, 68
Show/Hide
|
C24H27ClN2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0466876
|
US9067871, 24
Show/Hide
|
C24H26Cl2N2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0492540
|
US9067871, 75
Show/Hide
|
C22H28Cl2N2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0513420
|
US9067871, 57
Show/Hide
|
C24H28ClN3O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0516229
|
US9067871, 50
Show/Hide
|
C26H29ClN2O5S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0516789
|
US9067871, 16
Show/Hide
|
C25H26Cl2N2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0553379
|
US9067871, 36
Show/Hide
|
C23H26ClF2NO3
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0556449
|
US9067871, 73
Show/Hide
|
C24H26Cl2N2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0556479
|
US9067871, 72
Show/Hide
|
C23H24Cl2N2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0557619
|
US9067871, 17
Show/Hide
|
C23H24Cl2N2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0557623
|
US9067871, 78
Show/Hide
|
C26H35ClN2O5S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0564937
|
US9067871, 83
Show/Hide
|
C23H29ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0565650
|
US9067871, 7
Show/Hide
|
C25H32Cl2N2O5S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0566388
|
US9067871, 69
Show/Hide
|
C25H29ClN2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0566968
|
US9067871, 52
Show/Hide
|
C26H30ClN3O5S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0962965
|
US9067871, 58
Show/Hide
|
C23H27ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0394095
|
US8653100, 187
Show/Hide
|
C26H36ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0441558
|
US8653100, 81
Show/Hide
|
C26H33ClN2O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0441969
|
US8653100, 74
Show/Hide
|
C24H30FN3O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0441970
|
US8653100, 132
Show/Hide
|
C26H36ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0441971
|
US8653100, 133
Show/Hide
|
C26H34ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0441972
|
US8653100, 200
Show/Hide
|
C29H40ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0446260
|
US8653100, 59
Show/Hide
|
C29H35ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0454013
|
US8653100, 106
Show/Hide
|
C25H27FN2O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0480940
|
US8653100, 117
Show/Hide
|
C25H33ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0499836
|
US8653100, 108
Show/Hide
|
C25H26ClN3O2S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0499837
|
US8653100, 186
Show/Hide
|
C27H38ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0503620
|
US8653100, 118
Show/Hide
|
C26H35ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0506884
|
US8653100, 19
Show/Hide
|
C28H31ClN2O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0506885
|
US8653100, 23
Show/Hide
|
C28H28ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0506887
|
US8653100, 33
Show/Hide
|
C25H32ClN3O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0508986
|
US8653100, 47
Show/Hide
|
C25H33ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0520330
|
US8653100, 6
Show/Hide
|
C23H27ClN2O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0520331
|
US8653100, 9
Show/Hide
|
C31H31ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0520332
|
US8653100, 34
Show/Hide
|
C28H30ClN3O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0520335
|
US8653100, 68
Show/Hide
|
C24H31ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0535568
|
US8653100, 112
Show/Hide
|
C28H31ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0535598
|
US8653100, 32
Show/Hide
|
C28H31ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0535600
|
US8653100, 48
Show/Hide
|
C25H30ClN3O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0535601
|
US8653100, 56
Show/Hide
|
C28H39ClN4O5S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0535602
|
US8653100, 78
Show/Hide
|
C26H36ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0536978
|
US8653100, 3
Show/Hide
|
C28H29ClN2O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0536979
|
US8653100, 11
Show/Hide
|
C22H24ClF3N2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0539548
|
US8653100, 126
Show/Hide
|
C29H40ClN3O5S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0539549
|
US8653100, 155
Show/Hide
|
C26H35ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0539710
|
US8653100, 167
Show/Hide
|
C26H26Cl2N4O3S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0544390
|
US8653100, 176
Show/Hide
|
C27H30Cl2N2O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0548590
|
US8653100, 121
Show/Hide
|
C29H33ClN2O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0548591
|
US8653100, 165
Show/Hide
|
C26H29ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0548592
|
US8653100, 183
Show/Hide
|
C28H39ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0555337
|
US8653100, 1
Show/Hide
|
C28H27Cl3N2O2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0555345
|
US8653100, 181
Show/Hide
|
C26H36ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0556513
|
US8653100, 54
Show/Hide
|
C28H37ClN4O5S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0556514
|
US8653100, 60
Show/Hide
|
C24H33ClN2O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0560562
|
US8653100, 55
Show/Hide
|
C25H33ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0560679
|
US8653100, 22
Show/Hide
|
C28H28ClN3O4S2
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0570467
|
US8653100, 194
Show/Hide
|
C28H40ClN3O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0570468
|
US8653100, 202
Show/Hide
|
C26H35ClN4O4S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0957323
|
US8653100, 52
Show/Hide
|
C26H31ClN4O3S
|
1
|
| 1 |
IC50 < 10000 nM
|
|
|
|
CP0451929
|
US9067871, 19
Show/Hide
|
C23H29Cl2N3O3S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0462657
|
US9067871, 35
Show/Hide
|
C17H17Cl2NO
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0466878
|
US9067871, 29
Show/Hide
|
C21H20Cl2F3NO5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0472347
|
US9067871, 10
Show/Hide
|
C27H29Cl2N3O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0492537
|
US9067871, 23
Show/Hide
|
C25H30Cl2N4O3S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0492538
|
US9067871, 32
Show/Hide
|
C21H20Cl2N2O2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0492539
|
US9067871, 65
Show/Hide
|
C24H31ClN2O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0517474
|
US9067871, 30
Show/Hide
|
C18H17ClN2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0542225
|
US9067871, 49
Show/Hide
|
C27H32ClN3O5S2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0550657
|
US9067871, 41
Show/Hide
|
C21H25Cl2FN2O2S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0553380
|
US9067871, 40
Show/Hide
|
C21H26Cl2N2O2S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0556443
|
US9067871, 37
Show/Hide
|
C25H24ClNO3
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0556445
|
US9067871, 38
Show/Hide
|
C23H28Cl2N2O2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0557618
|
US9067871, 12
Show/Hide
|
C23H28Cl2N2O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0563947
|
US9067871, 74
Show/Hide
|
C25H32Cl2N2O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0413117
|
US8653100, 201
Show/Hide
|
C28H38ClN3O4S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0480758
|
US8653100, 197
Show/Hide
|
C27H38ClN3O3S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0492517
|
US8653100, 84
Show/Hide
|
C30H42ClN3O5S2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0503618
|
US8653100, 39
Show/Hide
|
C28H38ClN3O4S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0508982
|
US8653100, 5
Show/Hide
|
C25H31ClN2O2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0520333
|
US8653100, 41
Show/Hide
|
C25H32ClN3O2S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0535628
|
US8653100, 135
Show/Hide
|
C25H33ClN2O4S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0539709
|
US8653100, 70
Show/Hide
|
C26H30F4N2O4S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0550983
|
US8653100, 36
Show/Hide
|
C25H32ClN3O2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0550984
|
US8653100, 179
Show/Hide
|
C31H32ClN3O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0555341
|
US8653100, 42
Show/Hide
|
C27H29ClN4O2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0555343
|
US8653100, 116
Show/Hide
|
C29H27ClN2O3S2
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0556517
|
US8653100, 130
Show/Hide
|
C24H32ClN3O3S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0570466
|
US8653100, 123
Show/Hide
|
C31H42ClN3O5S
|
1
|
| 1 |
IC50 < 100000 nM
|
|
|
|
CP0462069
|
(3R,4S)-N-[(1R)-2,3-dihydro-1H-inden-1-yl]-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-amine
Show/Hide
|
C23H25FN4O2S
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0392982
|
(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-N-[3-(trifluoromethyl)phenyl]pyrrolidin-3-amin
Show/Hide
|
C21H20F4N4O2S
|
1
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| 1 |
Ki = 2 nM
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CP0462064
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(3R,4S)-4-(1,3-dioxepan-2-yl)-1-(1-methylimidazol-4-yl)sulfonyl-N-[3-(trifluoromethoxy)phenyl]pyrrolidin-3-amine
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C20H25F3N4O5S
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1
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| 1 |
Ki = 2 nM
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CP0532819
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(3R,4S)-4-(1,3-dioxan-2-yl)-1-(1-methylimidazol-4-yl)sulfonyl-N-[3-(trifluoromethoxy)phenyl]pyrrolidin-3-amine
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C19H23F3N4O5S
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1
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| 1 |
Ki = 2 nM
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CP0547151
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(3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluoromethoxy)phenyl]-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-amine
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C21H19F5N4O3S
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1
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| 1 |
Ki = 2 nM
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CP0409112
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N-(3-chlorophenyl)-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-amine
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C20H20ClFN4O2S
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1
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| 1 |
Ki = 3 nM
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CP0462067
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4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonyl-N-[3-(trifluoromethyl)phenyl]pyrrolidin-3-amine
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C21H20F4N4O2S
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1
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| 1 |
Ki = 3 nM
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CP0532820
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(3R,4S)-1-(1-methylimidazol-4-yl)sulfonyl-4-[(2R)-oxan-2-yl]-N-[3-(trifluoromethoxy)phenyl]pyrrolidin-3-amine
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C20H25F3N4O4S
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1
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| 1 |
Ki = 3 nM
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CP0547149
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(3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluoromethyl)phenyl]-1-[(1-methyl-1H-1,2,3-triazol-4-yl)sulfonyl]pyrrolidin-3-amine
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C20H18F5N5O2S
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1
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| 1 |
Ki = 3 nM
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CP0552700
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(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]-N-[3-(trifluoromethoxy)phenyl]pyrrolidin-3-amine
Show/Hide
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C21H20F4N4O3S
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1
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| 1 |
Ki = 4 nM
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CP0462068
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4-(4-fluorophenyl)-N-[4-fluoro-3-(trifluoromethyl)phenyl]-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-amine
Show/Hide
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C21H19F5N4O2S
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1
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| 1 |
Ki = 5 nM
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CP0534923
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N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}-6-(trifluoromethyl)pyrimidin-4-amine
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C19H18F4N6O2S
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1
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| 1 |
Ki = 5 nM
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CP0552699
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4-[(3S,4R)-3-(4-fluorophenyl)-4-[[3-(trifluoromethoxy)phenoxy]methyl]pyrrolidin-1-yl]sulfonyl-1-methylimidazole
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C22H21F4N3O4S
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1
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| 1 |
Ki = 7 nM
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CP0392983
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N-{(3R,4S)-4-(4-fluorophenyl)-1-[(1-methyl-1H-imidazol-4-yl)sulfonyl]pyrrolidin-3-yl}-4-(trifluoromethyl)pyridin-2-amine
Show/Hide
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C20H19F4N5O2S
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1
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| 1 |
Ki = 8 nM
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CP0532822
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1-(1-methylimidazol-4-yl)sulfonyl-4-phenyl-N-[3-(trifluoromethyl)phenyl]pyrrolidin-3-amine
Show/Hide
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C21H21F3N4O2S
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1
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| 1 |
Ki = 8 nM
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CP0548124
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1-(1-methylimidazol-4-yl)sulfonyl-N-(3-methylphenyl)-4-phenylpyrrolidin-3-amine
Show/Hide
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C21H24N4O2S
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1
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| 1 |
Ki = 17 nM
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CP0481870
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N-(3-chlorophenyl)-4-(2-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-amine
Show/Hide
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C20H20ClFN4O2S
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1
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| 1 |
Ki = 21 nM
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CP0393237
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(3R,4S)-1-(1-methylimidazol-4-yl)sulfonyl-4-[(2S)-oxolan-2-yl]-N-[3-(trifluoromethoxy)phenyl]pyrrolidin-3-amine
Show/Hide
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C19H23F3N4O4S
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1
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| 1 |
Ki = 24 nM
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CP0520050
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[(3R,4S)-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-yl]-[3-(trifluoromethoxy)phenyl]methanone
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C22H19F4N3O4S
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1
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| 1 |
Ki = 29 nM
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CP0532823
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N-(3-chlorophenyl)-4-(3-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-amine
Show/Hide
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C20H20ClFN4O2S
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1
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| 1 |
Ki = 42 nM
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CP0393239
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3-[[(3R,4S)-1-(1-methylimidazol-4-yl)sulfonyl-4-phenylpyrrolidin-3-yl]amino]benzonitrile
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C21H21N5O2S
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1
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| 1 |
Ki = 49 nM
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CP0532821
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N-[[(3S,4S)-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-yl]methyl]-3-(trifluoromethoxy)aniline
Show/Hide
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C22H22F4N4O3S
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1
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| 1 |
Ki = 60 nM
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CP0541468
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4-[(3R,4S)-3-benzyl-4-phenylpyrrolidin-1-yl]sulfonyl-1-methylimidazole
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C21H23N3O2S
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1
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| 1 |
Ki = 93 nM
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CP0547150
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4-[(3R,4S)-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-yl]oxy-6-(trifluoromethyl)pyrimidine
Show/Hide
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C19H17F4N5O3S
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1
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| 1 |
Ki = 97 nM
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CP0389629
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N-[4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-yl]-2-(trifluoromethyl)pyridin-4-amine
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C20H19F4N5O2S
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1
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| 1 |
Ki = 118 nM
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CP0462065
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2-chloro-N-[1-(1-methylimidazol-4-yl)sulfonyl-4-phenylpyrrolidin-3-yl]-3-(trifluoromethyl)benzamide
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C22H20ClF3N4O3S
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1
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| 1 |
Ki = 198 nM
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CP0462066
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1-(1-methylimidazol-4-yl)sulfonyl-N,4-diphenylpyrrolidin-3-amine
Show/Hide
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C20H22N4O2S
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1
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| 1 |
Ki = 199 nM
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CP0393238
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(3R,4S)-4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonyl-N-[3-(trifluoromethoxy)phenyl]pyrrolidine-3-carboxamide
Show/Hide
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C22H20F4N4O4S
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1
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| 1 |
Ki = 360 nM
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CP0564997
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1-(1-methylimidazol-4-yl)sulfonyl-4-pyridin-3-yl-N-[3-(trifluoromethyl)phenyl]pyrrolidin-3-amine
Show/Hide
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C20H20F3N5O2S
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1
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| 1 |
Ki = 766 nM
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CP0481869
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N-[4-(4-fluorophenyl)-1-(1-methylimidazol-4-yl)sulfonylpyrrolidin-3-yl]-5-(trifluoromethyl)pyridin-3-amine
Show/Hide
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C20H19F4N5O2S
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1
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| 1 |
Ki = 1160 nM
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CP0534922
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1-(1-methylimidazol-4-yl)sulfonyl-N-(4-methylphenyl)-4-phenylpyrrolidin-3-amine
Show/Hide
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C21H24N4O2S
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1
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| 1 |
Ki = 1250 nM
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CP0409111
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1-(1-methylimidazol-4-yl)sulfonyl-N-(2-methylphenyl)-4-phenylpyrrolidin-3-amine
Show/Hide
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C21H24N4O2S
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1
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| 1 |
Ki = 1510 nM
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