Brief Information of the Compound and Protein
Compound Name
2-chloro-N-[(S)-[(2S)-1-methylpiperidin-2-yl]-phenylmethyl]-3-(trifluoromethyl)benzamide
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PubChem ID
CID: 11704260
SID: 16808945
Canonical SMILES
CN1CCCC[C@H]1[C@@H](NC(=O)c1cccc(c1Cl)C(F)(F)F)c1ccccc1
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Compound Formula C21H22ClF3N2O
Compound Structure
Protein Name
Sodium- and chloride-dependent glycine transporter 1
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P48067
Gene Name
SLC6A9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 2.5 nM
   TI
   LI
   LO
   TS
2
IC50 = 3 nM
   TI
   LI
   LO
   TS
CL000232 JAR Homo sapiens (Human)  1
1
IC50 = 7.51 nM
   TI
   LI
   LO
   TS