Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000232
Cell Line Name	JAR
Synonyms	Jar JAr JaR
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_0360
Disease	Gestational choriocarcinoma (NCIt: C4646) Gestational choriocarcinoma (ORDO: Orphanet_99926)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT00871, Sodium-dependent serotonin transporter

Protein Info

Compound ID	Compound Name	Compound Formula
CP0046806 Compound Info	(3S,4R)-3-[(1,3-benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine Show/Hide	C19H20FNO3	1
1	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0859391 Compound Info	(1S,2R)-1-(5-Chloro-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C18H21Cl2FN2O	1
1	IC50 = 2.8 nM Bioactivity Info	TI LI LO TS
CP0008168 Compound Info	CAS_136434-34-9 Show/Hide	C18H19NOS	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0431099 Compound Info	(R,S/S,R)-syn-1-((4-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O2	1
1	IC50 = 3 nM Bioactivity Info	TI LI LO TS
CP0402229 Compound Info	N-[2-[(6-chloro-1H-benzimidazol-4-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C20H20ClFN4O	1
1	IC50 = 4.5 nM Bioactivity Info	TI LI LO TS
CP0859701 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(5-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 5.5 nM Bioactivity Info	TI LI LO TS
CP0492306 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H23FN2O3	1
1	IC50 = 6.3 nM Bioactivity Info	TI LI LO TS
CP0183973 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C22H24F2N2O2	1
1	IC50 = 7 nM Bioactivity Info	TI LI LO TS
CP0035258 Compound Info	N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine Show/Hide	C17H18F3NO	4
1	IC50 = 9.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 10 nM Bioactivity Info	TI LI LO TS
3	IC50 = 32.4 nM Bioactivity Info	TI LI LO TS
4	IC50 = 39.4 nM Bioactivity Info	TI LI LO TS
CP0392495 Compound Info	N-[2-(2,3-dihydro-1-benzofuran-7-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H23FN2O2	1
1	IC50 = 9.7 nM Bioactivity Info	TI LI LO TS
CP0491216 Compound Info	(+/-)-Erythro--1-(5-chloro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H19ClN2O	1
1	IC50 = 10 nM Bioactivity Info	TI LI LO TS
CP0418751 Compound Info	(R)-3-(3-fluorophenyl)-3-(1H-indol-1-yl)-N-methylpropan-1-amine Show/Hide	C18H19FN2	1
1	IC50 = 14 nM Bioactivity Info	TI LI LO TS
CP0502822 Compound Info	N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-methyl-3,4-dihydro-2H-chromen-3-amine Show/Hide	C22H25FN2O2	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0424392 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-methylchromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 15 nM Bioactivity Info	TI LI LO TS
CP0372301 Compound Info	(R,S/S,R)-syn-1-((3-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O2	1
1	IC50 = 17 nM Bioactivity Info	TI LI LO TS
CP0381753 Compound Info	(3S)-(+)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 17.4 nM Bioactivity Info	TI LI LO TS
CP0375390 Compound Info	(3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 18.7 nM Bioactivity Info	TI LI LO TS
CP0415398 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(2-methoxyphenoxy)ethyl]propan-1-amine Show/Hide	C20H23FN2O2	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0430956 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-(2-quinoxalin-5-yloxyethyl)propan-1-amine Show/Hide	C21H21FN4O	1
1	IC50 = 20 nM Bioactivity Info	TI LI LO TS
CP0448258 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(5-fluoro-2-methoxyphenoxy)ethyl]propan-1-amine Show/Hide	C20H22F2N2O2	1
1	IC50 = 20.5 nM Bioactivity Info	TI LI LO TS
CP0845301 Compound Info	(1S,2R)-1-(2,3-Dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C18H22ClFN2O	1
1	IC50 = 21 nM Bioactivity Info	TI LI LO TS
CP0439587 Compound Info	(R,S/S,R)-syn-1-((4-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H21ClN2O	1
1	IC50 = 22 nM Bioactivity Info	TI LI LO TS
CP0381751 Compound Info	3-[ethyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	IC50 = 24.1 nM Bioactivity Info	TI LI LO TS
CP0491299 Compound Info	8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-N-methylchromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 = 24.3 nM Bioactivity Info	TI LI LO TS
CP0409153 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]propan-1-amine Show/Hide	C21H22FN3O	1
1	IC50 = 24.4 nM Bioactivity Info	TI LI LO TS
CP0469215 Compound Info	N-[2-[(7-fluoro-2,3-dihydro-1,4-benzodioxin-5-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H22F2N2O3	1
1	IC50 = 24.6 nM Bioactivity Info	TI LI LO TS
CP0401389 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 25.2 nM Bioactivity Info	TI LI LO TS
CP0054778 Compound Info	CAS_93413-69-5 Show/Hide	C17H27NO2	2
1	IC50 = 27 nM Bioactivity Info	TI LI LO TS
2	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0375387 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-ethyl-8-fluorochromane-5-carboxamide Show/Hide	C27H31F2N3O2	1
1	IC50 = 27.9 nM Bioactivity Info	TI LI LO TS
CP0398894 Compound Info	N-[2-(1-benzofuran-7-yloxy)ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H21FN2O2	1
1	IC50 = 28.1 nM Bioactivity Info	TI LI LO TS
CP0845289 Compound Info	(1S,2R)-1-(2,3-Dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride Show/Hide	C18H23ClN2O	1
1	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0398544 Compound Info	(+/-)-Erythro--1-(5-methoxy-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C19H22N2O2	1
1	IC50 = 31 nM Bioactivity Info	TI LI LO TS
CP0417466 Compound Info	(R,S/S,R)-syn-1-(methyl(m-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O	1
1	IC50 = 32 nM Bioactivity Info	TI LI LO TS
CP0375388 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-propylchromane-5-carboxamide Show/Hide	C28H33F2N3O2	1
1	IC50 = 32.7 nM Bioactivity Info	TI LI LO TS
CP0435004 Compound Info	(R,S/S,R)-syn-1-((4-fluorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H21FN2O	1
1	IC50 = 33 nM Bioactivity Info	TI LI LO TS
CP0428171 Compound Info	(3S)-3-{(cyclopropylmethyl)[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 36.3 nM Bioactivity Info	TI LI LO TS
CP0485851 Compound Info	(S)-3-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	1
1	IC50 = 37.3 nM Bioactivity Info	TI LI LO TS
CP0422130 Compound Info	(R,S/S,R)-syn-1-((3-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H21ClN2O	1
1	IC50 = 41 nM Bioactivity Info	TI LI LO TS
CP0404465 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-2-(1H-indol-3-yl)ethanamine Show/Hide	C21H23FN2O2	1
1	IC50 = 42.2 nM Bioactivity Info	TI LI LO TS
CP0394623 Compound Info	N-(cyclopropylmethyl)-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C25H29FN2O2	1
1	IC50 = 42.6 nM Bioactivity Info	TI LI LO TS
CP0496802 Compound Info	(R)-3-(ethyl(3-(5-fluoro-1H-indol-3-yl)propyl)amino)-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	1
1	IC50 = 42.7 nM Bioactivity Info	TI LI LO TS
CP0461387 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-(cyclopropylmethyl)-8-fluorochromane-5-carboxamide Show/Hide	C29H33F2N3O2	1
1	IC50 = 43.6 nM Bioactivity Info	TI LI LO TS
CP0441439 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-isopropylchromane-5-carboxamide Show/Hide	C28H33F2N3O2	1
1	IC50 = 44.7 nM Bioactivity Info	TI LI LO TS
CP0461386 Compound Info	(3R)-(-)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)-amino}-N-methylchromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 = 47 nM Bioactivity Info	TI LI LO TS
CP0051283 Compound Info	ATOMOXETINE Show/Hide	C17H21NO	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0443265 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(5-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C19H21FN2O	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0443266 Compound Info	(1S,2R)-1-(7-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18ClFN2O	1
1	IC50 = 48 nM Bioactivity Info	TI LI LO TS
CP0428982 Compound Info	(+/-)-Erythro--3-amino-1-(1H-indol-1-yl)-1-phenylpropan-2-ol Show/Hide	C17H18N2O	1
1	IC50 = 50 nM Bioactivity Info	TI LI LO TS
CP0472054 Compound Info	(1S,2R)-1-(5-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18BrFN2O	1
1	IC50 = 52 nM Bioactivity Info	TI LI LO TS
CP0376181 Compound Info	3-[cyclopropylmethyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 53.5 nM Bioactivity Info	TI LI LO TS
CP0435005 Compound Info	(R,S/S,R)-syn-1-(4-methoxyphenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol Show/Hide	C18H24N2O2	1
1	IC50 = 55 nM Bioactivity Info	TI LI LO TS
CP0496910 Compound Info	(3R)-3-{(cyclopropylmethyl)[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 59.7 nM Bioactivity Info	TI LI LO TS
CP0424391 Compound Info	(3S)-(+)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	IC50 = 59.9 nM Bioactivity Info	TI LI LO TS
CP0444092 Compound Info	N-[2-[(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H22F2N2O2	1
1	IC50 = 61.5 nM Bioactivity Info	TI LI LO TS
CP0408328 Compound Info	N-ethyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C23H27FN2O2	1
1	IC50 = 64 nM Bioactivity Info	TI LI LO TS
CP0461385 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-cyclopropyl-8-fluorochromane-5-carboxamide Show/Hide	C28H31F2N3O2	1
1	IC50 = 69.6 nM Bioactivity Info	TI LI LO TS
CP0434736 Compound Info	N-cyclobutyl-3-[cyclobutyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C29H33F2N3O2	1
1	IC50 = 70.6 nM Bioactivity Info	TI LI LO TS
CP0435003 Compound Info	(R,S/S,R)-syn-1-(methyl(p-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0492237 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-(2-quinolin-5-yloxyethyl)propan-1-amine Show/Hide	C22H22FN3O	1
1	IC50 = 73 nM Bioactivity Info	TI LI LO TS
CP0485558 Compound Info	(2S,3R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-olHydrochloride Show/Hide	C18H20N2O	1
1	IC50 = 74 nM Bioactivity Info	TI LI LO TS
CP0490690 Compound Info	(R,S/S,R)-syn-1-(methyl(phenyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H22N2O	1
1	IC50 = 76 nM Bioactivity Info	TI LI LO TS
CP0494697 Compound Info	(1S,2R)-1-(5-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18F2N2O	1
1	IC50 = 78 nM Bioactivity Info	TI LI LO TS
CP0496260 Compound Info	(1S,2R)-1-(5-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18ClFN2O	1
1	IC50 = 79 nM Bioactivity Info	TI LI LO TS
CP0449450 Compound Info	3-[cyclopropylmethyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 82.4 nM Bioactivity Info	TI LI LO TS
CP0864119 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(2-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 84 nM Bioactivity Info	TI LI LO TS
CP0453209 Compound Info	N-[2-(2,3-dihydro-1,4-benzodioxin-5-yloxy)ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C20H21FN2O3	1
1	IC50 = 84.7 nM Bioactivity Info	TI LI LO TS
CP0354473 Compound Info	N-[2-[(6-fluoro-3,4-dihydro-2H-chromen-8-yl)oxy]ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C21H22F2N2O2	1
1	IC50 = 86.4 nM Bioactivity Info	TI LI LO TS
CP0375158 Compound Info	1-(2-(dimethylamino)-1-(3-methoxyphenyl)ethyl)cyclohexanol Show/Hide	C17H27NO2	1
1	IC50 = 88 nM Bioactivity Info	TI LI LO TS
CP0433747 Compound Info	(+/-)-Erythro--1-(5-fluoro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H19FN2O	1
1	IC50 = 95 nM Bioactivity Info	TI LI LO TS
CP0375383 Compound Info	3-{Cyclobutyl[4-(4-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 103 nM Bioactivity Info	TI LI LO TS
CP0375892 Compound Info	N-[2-[(5-fluoro-1-benzofuran-7-yl)oxy]ethyl]-3-(5-fluoro-1H-indol-3-yl)propan-1-amine Show/Hide	C21H20F2N2O2	1
1	IC50 = 104 nM Bioactivity Info	TI LI LO TS
CP0846029 Compound Info	(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}chromane- Show/Hide	C25H29ClFN3O2	1
1	IC50 = 109 nM Bioactivity Info	TI LI LO TS
CP0417365 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol Show/Hide	C17H21FN2O	1
1	IC50 = 112 nM Bioactivity Info	TI LI LO TS
CP0431021 Compound Info	(1S,2R)-1-(7-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18BrFN2O	1
1	IC50 = 113 nM Bioactivity Info	TI LI LO TS
CP0381740 Compound Info	(3R)-8-fluoro-3-[[3-(5-fluoro-1H-indol-3-yl)propyl](methyl)amino]chromane-5-carboxamide Show/Hide	C22H23F2N3O2	1
1	IC50 = 116 nM Bioactivity Info	TI LI LO TS
CP0388179 Compound Info	1-(1-(4-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol Show/Hide	C16H24ClNO	1
1	IC50 = 123 nM Bioactivity Info	TI LI LO TS
CP0418491 Compound Info	8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}-chromane-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	IC50 = 128 nM Bioactivity Info	TI LI LO TS
CP0461384 Compound Info	3-{(Cyclopropylmethyl)[4-(7-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 138 nM Bioactivity Info	TI LI LO TS
CP0484988 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-N-cyclopentyl-8-fluorochromane-5-carboxamide Show/Hide	C31H37F2N3O2	1
1	IC50 = 144 nM Bioactivity Info	TI LI LO TS
CP0915599 Compound Info	(2S,3R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride Show/Hide	C18H21ClN2O	1
1	IC50 = 144 nM Bioactivity Info	TI LI LO TS
CP0398982 Compound Info	(S)-2-((4-(1H-Indol-3-yl)-5,6-dihydropyridin-1(2H)-yl)-methyl)-8-methyl-2,3-dihydro-[1,4]dioxino-[2,3-f]quinoline Show/Hide	C26H25N3O2	1
1	IC50 = 145 nM Bioactivity Info	TI LI LO TS
CP0401388 Compound Info	3-{[3-(5-Fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide Show/Hide	C24H28FN3O2	1
1	IC50 = 146 nM Bioactivity Info	TI LI LO TS
CP0375391 Compound Info	(3R)-(-)-3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N-methylchromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 147 nM Bioactivity Info	TI LI LO TS
CP0425330 Compound Info	3-(1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]propan-1-amine Show/Hide	C21H23N3O	1
1	IC50 = 154 nM Bioactivity Info	TI LI LO TS
CP0853149 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-[(3S)-3-methyl-2,3-dihydro-1H-indol-1-yl]propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 154 nM Bioactivity Info	TI LI LO TS
CP0384697 Compound Info	(+)-1-[(1S)-1-(3-Chlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol Show/Hide	C16H24ClNO	1
1	IC50 = 155 nM Bioactivity Info	TI LI LO TS
CP0419033 Compound Info	(1R,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H20N2O	1
1	IC50 = 161 nM Bioactivity Info	TI LI LO TS
CP0374271 Compound Info	(S)-1-(3-(methylamino)-1-phenylpropyl)-3-propyl-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C20H25N3O	1
1	IC50 = 166 nM Bioactivity Info	TI LI LO TS
CP0417468 Compound Info	(R,S/S,R)-syn-1-(4-chlorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol Show/Hide	C17H21ClN2O	1
1	IC50 = 167 nM Bioactivity Info	TI LI LO TS
CP0418781 Compound Info	(1S,2R)-1-(7-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18F2N2O	1
1	IC50 = 175 nM Bioactivity Info	TI LI LO TS
CP0386060 Compound Info	1-(1-(2-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol Show/Hide	C16H24ClNO	1
1	IC50 = 177 nM Bioactivity Info	TI LI LO TS
CP0375377 Compound Info	(3R)-(-)-8-Fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl](propyl)amino}chromane-5-carboxamide Show/Hide	C24H27F2N3O2	1
1	IC50 = 181 nM Bioactivity Info	TI LI LO TS
CP0399898 Compound Info	(R,S/S,R)-syn-3-amino-1-(4-methoxyphenyl)-1-(methyl(phenyl)amino)propan-2-ol Show/Hide	C17H22N2O2	1
1	IC50 = 183 nM Bioactivity Info	TI LI LO TS
CP0864120 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-[(3R)-3-methyl-2,3-dihydro-1H-indol-1-yl]propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 194 nM Bioactivity Info	TI LI LO TS
CP0509911 Compound Info	(R,S/S,R)-syn-3-amino-1-(methyl(phenyl)amino)-1-phenylpropan-2-ol Show/Hide	C16H20N2O	1
1	IC50 = 196 nM Bioactivity Info	TI LI LO TS
CP0376225 Compound Info	(3R)-8-fluoro-3-{[3-(5-fluoro-1H-indol-3-yl)propyl]amino}chromane-5-carboxamide Show/Hide	C21H21F2N3O2	1
1	IC50 = 197 nM Bioactivity Info	TI LI LO TS
CP0501006 Compound Info	(1S,2R)-1-(4-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18BrFN2O	1
1	IC50 = 207 nM Bioactivity Info	TI LI LO TS
CP0449452 Compound Info	8-fluoro-3-[4-(5-fluoro-1H-indol-3-yl)butyl-propylamino]-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 = 217 nM Bioactivity Info	TI LI LO TS
CP0399325 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluoro-N,N-dimethylchromane-5-carboxamide Show/Hide	C27H31F2N3O2	1
1	IC50 = 218 nM Bioactivity Info	TI LI LO TS
CP0418750 Compound Info	(1S,2R)-1-(4-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18ClFN2O	1
1	IC50 = 221 nM Bioactivity Info	TI LI LO TS
CP0496259 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(4-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C19H21FN2O	1
1	IC50 = 228 nM Bioactivity Info	TI LI LO TS
CP0493734 Compound Info	(R,S/S,R)-syn-1-(3-chlorophenyl)-1-(methyl(phenyl)amino)-3-(methylamino)propan-2-ol Show/Hide	C17H21ClN2O	1
1	IC50 = 237 nM Bioactivity Info	TI LI LO TS
CP0196465 Compound Info	(R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morpholine Show/Hide	C19H23NO3	1
1	IC50 = 242 nM Bioactivity Info	TI LI LO TS
CP0399965 Compound Info	N-[2-(5-fluoro-2-methoxyphenoxy)ethyl]-2-(1H-indol-3-yl)ethanamine Show/Hide	C19H21FN2O2	1
1	IC50 = 249 nM Bioactivity Info	TI LI LO TS
CP0463763 Compound Info	(+/-)-Erythro--1-(3-methyl-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 251 nM Bioactivity Info	TI LI LO TS
CP0376632 Compound Info	N-[2-[(5-fluoro-2,3-dihydro-1-benzofuran-7-yl)oxy]ethyl]-2-(5-fluoro-1H-indol-3-yl)ethanamine Show/Hide	C20H20F2N2O2	1
1	IC50 = 254 nM Bioactivity Info	TI LI LO TS
CP0439109 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-o-tolylpropan-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 266 nM Bioactivity Info	TI LI LO TS
CP0491820 Compound Info	(S)-1-(3-(methylamino)-1-phenylpropyl)-3-phenyl-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C23H23N3O	1
1	IC50 = 273 nM Bioactivity Info	TI LI LO TS
CP0101880 Compound Info	3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-amine Show/Hide	C17H21NO2	1
1	IC50 = 277 nM Bioactivity Info	TI LI LO TS
CP0845299 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(7-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 280 nM Bioactivity Info	TI LI LO TS
CP0485443 Compound Info	(R,S/S,R)-syn-1-((2-chlorophenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H21ClN2O	1
1	IC50 = 286 nM Bioactivity Info	TI LI LO TS
CP0375016 Compound Info	(R)-1-(1-(3-chlorophenyl)-3-(methylamino)propyl)-7-fluoro-3,3-dimethylindolin-2-one Show/Hide	C20H22ClFN2O	1
1	IC50 = 290 nM Bioactivity Info	TI LI LO TS
CP0376294 Compound Info	1-(1-(3-chlorophenyl)-2-(dimethylamino)ethyl)cyclohexanol Show/Hide	C16H24ClNO	1
1	IC50 = 292 nM Bioactivity Info	TI LI LO TS
CP0418156 Compound Info	(+/-)-Erythro--3-(ethylamino)-1-(1H-indol-1-yl)-1-phenylpropan-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 298 nM Bioactivity Info	TI LI LO TS
CP0455224 Compound Info	(+/-)-Erythro--3-amino-1-(3-methyl-1H-indol-1-yl)-1-phenylpropan-2-ol Show/Hide	C18H20N2O	1
1	IC50 = 299 nM Bioactivity Info	TI LI LO TS
CP0381735 Compound Info	3-[cyclobutyl-[4-(5-fluoro-1H-indol-3-yl)butyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 = 300 nM Bioactivity Info	TI LI LO TS
CP0448769 Compound Info	3-(5-fluoro-1H-indol-3-yl)-N-[2-(5,6,7,8-tetrahydronaphthalen-1-yloxy)ethyl]propan-1-amine Show/Hide	C23H27FN2O	1
1	IC50 = 305 nM Bioactivity Info	TI LI LO TS
CP0374268 Compound Info	3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine Show/Hide	C18H20N2	1
1	IC50 = 327 nM Bioactivity Info	TI LI LO TS
CP0853151 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-(3-methyl-2,3-dihydro-1H-indol-1-yl)propan-2-ol Hydrochloride Show/Hide	C19H24ClFN2O	1
1	IC50 = 329 nM Bioactivity Info	TI LI LO TS
CP0434278 Compound Info	(R)-1-(1-(3,5-difluorophenyl)-3-(methylamino)propyl)-7-fluoro-3,3-dimethylindolin-2-one Show/Hide	C20H21F3N2O	1
1	IC50 = 330 nM Bioactivity Info	TI LI LO TS
CP0494695 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(3-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C19H21FN2O	1
1	IC50 = 343 nM Bioactivity Info	TI LI LO TS
CP0089680 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H20N2O	1
1	IC50 = 358 nM Bioactivity Info	TI LI LO TS
CP0853047 Compound Info	(1S,2R)-1-(5-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H25ClF2N2O	1
1	IC50 = 364 nM Bioactivity Info	TI LI LO TS
CP0401546 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-m-tolylpropan-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 377 nM Bioactivity Info	TI LI LO TS
CP0424389 Compound Info	(3R)-(-)-8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	IC50 = 379 nM Bioactivity Info	TI LI LO TS
CP0252376 Compound Info	N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propyl-3,4-dihydro-2H-chromen-3-amine Show/Hide	C24H29FN2O2	1
1	IC50 = 386 nM Bioactivity Info	TI LI LO TS
CP0494696 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-p-tolylpropan-2-ol Show/Hide	C19H22N2O	1
1	IC50 = 398 nM Bioactivity Info	TI LI LO TS
CP0376227 Compound Info	N-cyclobutyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-3,4-dihydro-2H-chromen-3-amine Show/Hide	C25H29FN2O2	1
1	IC50 = 400 nM Bioactivity Info	TI LI LO TS
CP0375154 Compound Info	(-)-1-[(1R)-1-(3-Chlorophenyl)-2-(dimethylamino)ethyl]cyclohexanol Show/Hide	C16H24ClNO	1
1	IC50 = 405 nM Bioactivity Info	TI LI LO TS
CP0475059 Compound Info	(R,R/S,S)-anti-1-(methyl(phenyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C17H22N2O	1
1	IC50 = 416 nM Bioactivity Info	TI LI LO TS
CP0496254 Compound Info	(1S,2R)-1-(4-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18F2N2O	1
1	IC50 = 417 nM Bioactivity Info	TI LI LO TS
CP0418500 Compound Info	8-Fluoro-3-[[4-(7-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 = 435 nM Bioactivity Info	TI LI LO TS
CP0522115 Compound Info	(R,S/S,R)-syn-3-amino-1-(3-fluorophenyl)-1-(methyl(phenyl)amino)propan-2-ol Show/Hide	C16H19FN2O	1
1	IC50 = 439 nM Bioactivity Info	TI LI LO TS
CP0496252 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19FN2O	1
1	IC50 = 441 nM Bioactivity Info	TI LI LO TS
CP0375385 Compound Info	8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	IC50 = 442 nM Bioactivity Info	TI LI LO TS
CP0375376 Compound Info	(3S)-(+)-8-Fluoro-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxy-N-propylchroman-3-amine Show/Hide	C24H28F2N2O2	1
1	IC50 = 452 nM Bioactivity Info	TI LI LO TS
CP0499128 Compound Info	(1S,2R)-1-(2-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19FN2O	1
1	IC50 = 473 nM Bioactivity Info	TI LI LO TS
CP0521188 Compound Info	(R)-4-fluoro-1-(2-fluorophenyl)-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C23H21F2N3O	1
1	IC50 = 483 nM Bioactivity Info	TI LI LO TS
CP0441310 Compound Info	(R)-3-(1H-indol-1-yl)-N-methyl-3-phenylpropan-1-amine Show/Hide	C18H20N2	1
1	IC50 = 491 nM Bioactivity Info	TI LI LO TS
CP0853046 Compound Info	(1S,2R)-1-(3-Ethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H26ClFN2O	1
1	IC50 = 499 nM Bioactivity Info	TI LI LO TS
CP0431022 Compound Info	(1S,2R)-1-(3-fluorophenyl)-1-(7-methyl-1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C19H21FN2O	1
1	IC50 = 527 nM Bioactivity Info	TI LI LO TS
CP0378521 Compound Info	1-(2-(dimethylamino)-1-(3-(trifluoromethyl)phenyl)ethyl)cyclohexanol Show/Hide	C17H24F3NO	1
1	IC50 = 534 nM Bioactivity Info	TI LI LO TS
CP0401545 Compound Info	(1S,2R)-1-(3-bromophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19BrN2O	1
1	IC50 = 547 nM Bioactivity Info	TI LI LO TS
CP0388214 Compound Info	(1S,2R)-1-(3-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19ClN2O	1
1	IC50 = 554 nM Bioactivity Info	TI LI LO TS
CP0375378 Compound Info	3-[[3-(5-Chloro-1H-indol-3-yl)propyl](cyclobutyl)amino]-8-fluorochromane-5-carboxamide Show/Hide	C25H27ClFN3O2	1
1	IC50 = 612 nM Bioactivity Info	TI LI LO TS
CP0496253 Compound Info	(1S,2R)-1-(6-fluoro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18F2N2O	1
1	IC50 = 626 nM Bioactivity Info	TI LI LO TS
CP0399324 Compound Info	(3R)-(-)-N-Cyclobutyl-N-[3-(5-fluoro-1H-indol-3-yl)propyl]-5-methoxychroman-3-amine Show/Hide	C25H29FN2O2	1
1	IC50 = 732 nM Bioactivity Info	TI LI LO TS
CP0501007 Compound Info	(1S,2R)-1-(4-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19ClN2O	1
1	IC50 = 748 nM Bioactivity Info	TI LI LO TS
CP0494415 Compound Info	3-(3-methoxyphenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C19H23N3O4S	1
1	IC50 = 749 nM Bioactivity Info	TI LI LO TS
CP0434735 Compound Info	8-Fluoro-3-[[4-(6-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 = 776 nM Bioactivity Info	TI LI LO TS
CP0501282 Compound Info	5-fluoro-3-(2-fluorophenyl)-1-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H19F2N3O3S	1
1	IC50 = 806 nM Bioactivity Info	TI LI LO TS
CP0902378 Compound Info	(1S,2R)-1-[5-(Benzyloxy)-2,3-dihydro-1H-indol-1-yl]-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C25H28ClFN2O2	1
1	IC50 = 813 nM Bioactivity Info	TI LI LO TS
CP0401387 Compound Info	3-{Cyclobutyl[3-(5-methoxy-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H30FN3O3	1
1	IC50 = 834 nM Bioactivity Info	TI LI LO TS
CP0418749 Compound Info	(1S,2R)-1-(3-ethyl-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C20H23FN2O	1
1	IC50 = 834 nM Bioactivity Info	TI LI LO TS
CP0372302 Compound Info	(R,S/S,R)-syn-1-(methyl(naphthalen-1-yl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C21H24N2O	1
1	IC50 = 836 nM Bioactivity Info	TI LI LO TS
CP0415516 Compound Info	4-(1H-indol-3-yl)-N-[2-(1H-indol-4-yloxy)ethyl]butan-1-amine Show/Hide	C22H25N3O	1
1	IC50 = 862 nM Bioactivity Info	TI LI LO TS
CP0418923 Compound Info	(1S,2R)-1-(6-chloro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18ClFN2O	1
1	IC50 = 865 nM Bioactivity Info	TI LI LO TS
CP0494683 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-1-(3-methoxyphenyl)-3-(methylamino)propan-2-ol Show/Hide	C19H22N2O2	1
1	IC50 = 882 nM Bioactivity Info	TI LI LO TS
CP0381752 Compound Info	3-[ethyl-[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C22H23F2N3O2	1
1	IC50 = 883 nM Bioactivity Info	TI LI LO TS
CP0401090 Compound Info	3-{Cyclobutyl[3-(6-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C25H27F2N3O2	1
1	IC50 = 899 nM Bioactivity Info	TI LI LO TS
CP0455225 Compound Info	(+/-)-Erythro-1-(1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H20N2O	1
1	IC50 = 918 nM Bioactivity Info	TI LI LO TS
CP0498694 Compound Info	4-fluoro-1-(2-fluorophenyl)-3-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H19F2N3O3S	1
1	IC50 = 992 nM Bioactivity Info	TI LI LO TS
CP0494694 Compound Info	(1S,2R)-1-(6-bromo-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Show/Hide	C18H18BrFN2O	1
1	IC50 = 1003 nM Bioactivity Info	TI LI LO TS
CP0401088 Compound Info	3-{Cyclobutyl[3-(5-fluoro-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxylic Acid Show/Hide	C25H26F2N2O3	1
1	IC50 = 1026 nM Bioactivity Info	TI LI LO TS
CP0458791 Compound Info	1-[2-[(2S)-morpholin-2-yl]ethyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H21N3O3S	1
1	IC50 = 1030 nM Bioactivity Info	TI LI LO TS
CP0706369 Compound Info	(1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride Show/Hide	C20H26ClFN2O	1
1	IC50 = 1099 nM Bioactivity Info	TI LI LO TS
CP0899678 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-1-(3-isopropyl-2,3-dihydro-1Hindol-1-yl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C21H28ClFN2O	1
1	IC50 = 1123 nM Bioactivity Info	TI LI LO TS
CP0428142 Compound Info	1'-[(1S)-1-(3-fluorophenyl)-3-(methylamino)propyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one Show/Hide	C23H27FN2O	1
1	IC50 = 1150 nM Bioactivity Info	TI LI LO TS
CP0374270 Compound Info	(R)-4-fluoro-1-isopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C20H24FN3O	1
1	IC50 = 1208 nM Bioactivity Info	TI LI LO TS
CP0897101 Compound Info	1-{2-(4-Methylpiperazin-1-yl)-1-[4-(trifluoromethoxy)phenyl]ethyl}cyclohexanol Dihydrocholoride Show/Hide	C20H31Cl2F3N2O2	1
1	IC50 = 1214 nM Bioactivity Info	TI LI LO TS
CP0496255 Compound Info	(1S,2R)-1-(2-chlorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19ClN2O	1
1	IC50 = 1333 nM Bioactivity Info	TI LI LO TS
CP0428136 Compound Info	(R)-3,3-dimethyl-1-(3-(methylamino)-1-phenylpropyl)indolin-2-one Show/Hide	C20H24N2O	1
1	IC50 = 1350 nM Bioactivity Info	TI LI LO TS
CP0443274 Compound Info	(1S,2R)-1-(4-fluorophenyl)-1-(1H-indol-1-yl)-3-(methylamino)propan-2-ol Show/Hide	C18H19FN2O	1
1	IC50 = 1366 nM Bioactivity Info	TI LI LO TS
CP0375861 Compound Info	1-[2-[(2R)-morpholin-2-yl]ethyl]-3-(2,4,6-trifluorophenyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H18F3N3O3S	1
1	IC50 = 1400 nM Bioactivity Info	TI LI LO TS
CP0437723 Compound Info	(S)-4-fluoro-1-isopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C20H24FN3O	1
1	IC50 = 1408 nM Bioactivity Info	TI LI LO TS
CP0852054 Compound Info	1-[1-(4-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride Show/Hide	C18H29Cl3N2O	1
1	IC50 = 1525 nM Bioactivity Info	TI LI LO TS
CP0706370 Compound Info	(1S,2R)-1-(7-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H25ClF2N2O	1
1	IC50 = 1614 nM Bioactivity Info	TI LI LO TS
CP0375015 Compound Info	1'-[(1S)-3-(methylamino)-1-phenylpropyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one Show/Hide	C23H28N2O	1
1	IC50 = 1750 nM Bioactivity Info	TI LI LO TS
CP0458790 Compound Info	1-(2-morpholin-2-ylethyl)-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H21N3O3S	1
1	IC50 = 1775 nM Bioactivity Info	TI LI LO TS
CP0424386 Compound Info	methyl 3-[cyclobutyl-[3-(5-fluoro-1H-indol-3-yl)propyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxylate Show/Hide	C26H28F2N2O3	1
1	IC50 = 1860 nM Bioactivity Info	TI LI LO TS
CP0479027 Compound Info	(R)-3-(3-(methylamino)-1-phenylpropyl)benzo[d]thiazol-2(3H)-one Show/Hide	C17H18N2OS	1
1	IC50 = 1910 nM Bioactivity Info	TI LI LO TS
CP0434279 Compound Info	(S)-3,3-dimethyl-1-(3-(methylamino)-1-phenylpropyl)indolin-2-one Show/Hide	C20H24N2O	1
1	IC50 = 1950 nM Bioactivity Info	TI LI LO TS
CP0853153 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro[cyclopentane-1,3'-indol]-1'(2'H)-ylpropan-2-ol Hydrochloride Show/Hide	C22H28ClFN2O	1
1	IC50 = 1969 nM Bioactivity Info	TI LI LO TS
CP0489428 Compound Info	4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-N-methylbutan-1-amine Show/Hide	C17H20FN3O2S	1
1	IC50 = 2042 nM Bioactivity Info	TI LI LO TS
CP0435002 Compound Info	(R,S/S,R)-syn-1-((2-methoxyphenyl)(methyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O2	1
1	IC50 = 2105 nM Bioactivity Info	TI LI LO TS
CP0404457 Compound Info	3-(1H-indol-3-yl)-N-(2-naphthalen-1-yloxyethyl)propan-1-amine Show/Hide	C23H24N2O	1
1	IC50 = 2170 nM Bioactivity Info	TI LI LO TS
CP0443267 Compound Info	(1S,2R)-1-(1H-indol-1-yl)-3-(methylamino)-1-(3-(trifluoromethyl)phenyl)propan-2-ol Show/Hide	C19H19F3N2O	1
1	IC50 = 2184 nM Bioactivity Info	TI LI LO TS
CP0439256 Compound Info	(+/-)-Erythro--3-(ethylamino)-1-(3-methyl-1H-indol-1-yl)-1-phenylpropan-2-ol Show/Hide	C20H24N2O	1
1	IC50 = 2200 nM Bioactivity Info	TI LI LO TS
CP0434276 Compound Info	(R)-7-fluoro-1-(1-(3-fluorophenyl)-3-(methylamino)propyl)-3,3-dimethylindolin-2-one Show/Hide	C20H22F2N2O	1
1	IC50 = 2550 nM Bioactivity Info	TI LI LO TS
CP0372303 Compound Info	(1S,2R)-1-(methyl(o-tolyl)amino)-3-(methylamino)-1-phenylpropan-2-ol Show/Hide	C18H24N2O	1
1	IC50 = 2607 nM Bioactivity Info	TI LI LO TS
CP0850318 Compound Info	(+)-1-[(1S)-1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride Show/Hide	C18H29Cl3N2O	1
1	IC50 = 2669 nM Bioactivity Info	TI LI LO TS
CP0398532 Compound Info	(+/-)-Erythro--3-(cyclohexylmethylamino)-1-(1H-indol-1-yl)-1-phenylpropan-2-ol Show/Hide	C24H30N2O	1
1	IC50 = 2833 nM Bioactivity Info	TI LI LO TS
CP0706368 Compound Info	(1S,2R)-1-(3,3-Dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)-1-phenylpropan-2-ol Hydrochloride Show/Hide	C20H27ClN2O	1
1	IC50 = 2871 nM Bioactivity Info	TI LI LO TS
CP0375853 Compound Info	3-phenyl-1-(2-piperidin-3-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C19H23N3O2S	1
1	IC50 = 2983 nM Bioactivity Info	TI LI LO TS
CP0419035 Compound Info	(R)-1-(3-(methylamino)-1-phenylpropyl)-3-phenyl-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C23H23N3O	1
1	IC50 = 2995 nM Bioactivity Info	TI LI LO TS
CP0437722 Compound Info	(R)-1-(3-(methylamino)-1-phenylpropyl)-3-propyl-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C20H25N3O	1
1	IC50 = 3100 nM Bioactivity Info	TI LI LO TS
CP0095515 Compound Info	(2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol Show/Hide	C17H20FN3O3S	1
1	IC50 = 3380 nM Bioactivity Info	TI LI LO TS
CP0866951 Compound Info	[3-(5-Fluoro-1H-indol-2-yl)-propyl]-(2-phenoxy-ethyl)-amine Show/Hide	C19H21FN2O	1
1	IC50 = 3790 nM Bioactivity Info	TI LI LO TS
CP0458793 Compound Info	3-(2,4-difluorophenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H19F2N3O3S	1
1	IC50 = 4128 nM Bioactivity Info	TI LI LO TS
CP0474688 Compound Info	(R)-1-ethyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C19H23N3O	1
1	IC50 = 4311 nM Bioactivity Info	TI LI LO TS
CP0652323 Compound Info	(1S,2R)-1-(3,3-Dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H26ClFN2O	1
1	IC50 = 4519 nM Bioactivity Info	TI LI LO TS
CP0491818 Compound Info	(R)-1-cyclopropyl-3-(3-(methylamino)-1-phenylpropyl)-1H-benzo[d]imidazol-2(3H)-one Show/Hide	C20H23N3O	1
1	IC50 = 4565 nM Bioactivity Info	TI LI LO TS
CP0901042 Compound Info	4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ol Show/Hide	C17H20FN3O3S	1
1	IC50 = 4589 nM Bioactivity Info	TI LI LO TS
CP0845300 Compound Info	(1S,2R)-1-(3-Fluorophenyl)-3-(methylamino)-1-spiro[cyclohexane-1,30-indol]-1'(2'H)-ylpropan-2-ol Hydrochloride Show/Hide	C23H30ClFN2O	1
1	IC50 = 4917 nM Bioactivity Info	TI LI LO TS
CP0851787 Compound Info	1-[1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride Show/Hide	C18H29Cl3N2O	1
1	IC50 = 4962 nM Bioactivity Info	TI LI LO TS
CP0845208 Compound Info	(1S,2R)-1-(6-Fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H25ClF2N2O	1
1	IC50 = 4992 nM Bioactivity Info	TI LI LO TS
CP0375856 Compound Info	(2R)-4-(2,2-dioxo-3-phenyl-2lambda6,1,3-benzothiadiazol-1-yl)-2-methoxy-N-methylbutan-1-amine Show/Hide	C18H23N3O3S	1
1	IC50 = 5100 nM Bioactivity Info	TI LI LO TS
CP0652324 Compound Info	(1S,2R)-1-(3,5-Difluorophenyl)-1-(3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C20H25ClF2N2O	1
1	IC50 = 5293 nM Bioactivity Info	TI LI LO TS
CP0375863 Compound Info	4-fluoro-3-(2-fluorophenyl)-1-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H19F2N3O3S	1
1	IC50 = 5790 nM Bioactivity Info	TI LI LO TS
CP0921911 Compound Info	(-)-1-[(1R)-1-(3-Chlorophenyl)-2-piperazin-1-ylethyl]cyclohexanol Dihydrochloride Show/Hide	C18H29Cl3N2O	1
1	IC50 = 6102 nM Bioactivity Info	TI LI LO TS
CP0375860 Compound Info	3-(2-fluorophenyl)-1-[2-[(2R)-morpholin-2-yl]ethyl]-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H20FN3O3S	1
1	IC50 = 6410 nM Bioactivity Info	TI LI LO TS
CP0375858 Compound Info	1-[2-[(2R)-morpholin-2-yl]ethyl]-3-phenyl-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H21N3O3S	1
1	IC50 = 6770 nM Bioactivity Info	TI LI LO TS
CP0375862 Compound Info	5-fluoro-1-(2-fluorophenyl)-3-(2-morpholin-2-ylethyl)-2lambda6,1,3-benzothiadiazole 2,2-dioxide Show/Hide	C18H19F2N3O3S	1
1	IC50 = 8347 nM Bioactivity Info	TI LI LO TS
CP0853152 Compound Info	(1S,2R)-1-(3,3-Diethyl-2,3-dihydro-1H-indol-1-yl)-1-(3-fluorophenyl)-3-(methylamino)propan-2-ol Hydrochloride Show/Hide	C22H30ClFN2O	1
1	IC50 = 8971 nM Bioactivity Info	TI LI LO TS
CP0851788 Compound Info	1-[1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride Show/Hide	C19H31Cl3N2O	1
1	IC50 = 18795 nM Bioactivity Info	TI LI LO TS
CP0394637 Compound Info	8-fluoro-3-[2-(5-fluoro-1H-indol-3-yl)ethyl-propylamino]-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C23H25F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0449451 Compound Info	3-[cyclopropylmethyl-[2-(5-fluoro-1H-indol-3-yl)ethyl]amino]-8-fluoro-3,4-dihydro-2H-chromene-5-carboxamide Show/Hide	C24H25F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0374997 Compound Info	3-{(Cyclopropylmethyl)[4-(5-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0375381 Compound Info	3-[[3-(7-Chloro-1H-indol-3-yl)propyl](cyclobutyl)amino]-8-fluorochromane-5-carboxamide Show/Hide	C25H27ClFN3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0375389 Compound Info	(3R)-(+)-8-Fluoro-3-[{[6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl]methyl}(propyl)amino]chromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0401086 Compound Info	3-{Cyclobutyl[3-(7-methoxy-1H-indol-3-yl)propyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H30FN3O3	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0401087 Compound Info	8-Fluoro-3-[[4-(4-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0401089 Compound Info	(3R)-(+)-3-((Cyclopropylmethyl){[6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-3-yl]methyl}amino)-8-fluorochromane-5-carboxamide Show/Hide	C27H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0401383 Compound Info	3-{(Cyclopropylmethyl)[4-(6-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0418502 Compound Info	3-{(Cyclopropylmethyl)[4-(4-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0424390 Compound Info	3-{Cyclobutyl[4-(5-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0439150 Compound Info	8-Fluoro-3-[[4-(5-fluoro-1H-indol-1-yl)butyl](propyl)amino]chromane-5-carboxamide Show/Hide	C25H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0456179 Compound Info	3-{Cyclobutyl[4-(7-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0461388 Compound Info	3-{Cyclobutyl[4-(6-fluoro-1H-indol-1-yl)butyl]amino}-8-fluorochromane-5-carboxamide Show/Hide	C26H29F2N3O2	1
1	IC50 > 1000 nM Bioactivity Info	TI LI LO TS
CP0401456 Compound Info	1-[1-(3-Chlorophenyl)-2-(4-methylpiperazin-1-yl)ethyl]cyclohexanol Dihydrocholoride Show/Hide	C19H29ClN2O	1
1	IC50 > 2000 nM Bioactivity Info	TI LI LO TS
CP0417752 Compound Info	1'-[(1R)-3-(methylamino)-1-phenylpropyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one Show/Hide	C23H28N2O	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0428137 Compound Info	1'-[(1R)-1-(3-fluorophenyl)-3-(methylamino)propyl]-1',2'-dihydrospiro[cyclohexane-1,3'-indole]-2'-one Show/Hide	C23H27FN2O	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0489375 Compound Info	(R)-7-fluoro-3,3-dimethyl-1-(3-(methylamino)-1-phenylpropyl)indolin-2-one Show/Hide	C20H23FN2O	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0504293 Compound Info	(R)-1-(1-(3-chloro-5-fluorophenyl)-3-(methylamino)propyl)-7-fluoro-3,3-dimethylindolin-2-one Show/Hide	C20H21ClF2N2O	1
1	IC50 > 3000 nM Bioactivity Info	TI LI LO TS
CP0037866 Compound Info	CAS_146714-97-8 Show/Hide	C25H34N4O2	1
1	IC50 > 4500 nM Bioactivity Info	TI LI LO TS
CP0089468 Compound Info	3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-6-fluoro-1H-indole Show/Hide	C23H23FN2O3	1
1	Ki = 19.8 nM Bioactivity Info	TI LI LO TS
CP0052590 Compound Info	1H-4-indolyl 2-[4-(1H-3-indolyl)-1,2,3,6-tetrahydro-1-pyridinyl]ethyl ether Show/Hide	C23H23N3O	1
1	Ki = 41.2 nM Bioactivity Info	TI LI LO TS
CP0181933 Compound Info	3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-indole Show/Hide	C23H24N2O3	1
1	Ki = 45 nM Bioactivity Info	TI LI LO TS
CP0081364 Compound Info	3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-5-fluoro-1H-indole Show/Hide	C23H23FN2O3	1
1	Ki = 46.9 nM Bioactivity Info	TI LI LO TS
CP0038412 Compound Info	5-{2-[4-(1H-Indol-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethoxy}-quinoline Show/Hide	C24H23N3O	1
1	Ki = 93.6 nM Bioactivity Info	TI LI LO TS
CP0065213 Compound Info	3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-piperidin-4-yl}-6-fluoro-1H-indole Show/Hide	C23H25FN2O3	1
1	Ki = 127.8 nM Bioactivity Info	TI LI LO TS
CP0209926 Compound Info	3-{1-[2-(1H-Indol-4-yloxy)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-pyrrolo[2,3-b]pyridine Show/Hide	C22H22N4O	1
1	Ki = 175 nM Bioactivity Info	TI LI LO TS
CP0150137 Compound Info	3-{1-[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-1,2,3,6-tetrahydro-pyridin-4-yl}-1H-pyrrolo[2,3-b]pyridine Show/Hide	C22H23N3O3	1
1	Ki = 276 nM Bioactivity Info	TI LI LO TS
CP0299469 Compound Info	5-{2-[4-(1H-Pyrrolo[2,3-b]pyridin-3-yl)-3,6-dihydro-2H-pyridin-1-yl]-ethoxy}-quinoline Show/Hide	C23H22N4O	1
1	Ki = 387 nM Bioactivity Info	TI LI LO TS

Protein ID: PT02185, Solute carrier family 6 member 9

Protein Info

Protein family and CMB statistics Related to the Cell Line

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han