| Compound ID |
Compound Name |
Compound Formula |
|
CP0542884
|
1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl)-1,2,4- oxadiazol-5-yl)methyl)- 7-methyl-1,7-dihydro- 6H-purin-6-one
Show/Hide
|
C19H17ClN6O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0512070
|
US9186360, 57
Show/Hide
|
C21H15Cl2F3N4O5S
|
1
|
| 1 |
IC50 = 1.45 nM
|
|
|
|
CP0480208
|
(2S,4R,5S)-4-fluoro-1-(4-fluorophenyl)sulfonyl-5-methyl-N-[[5-(trifluoromethyl)-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C24H19F8N5O3S
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0441116
|
US9186360, 62
Show/Hide
|
C22H17F5N4O5S
|
1
|
| 1 |
IC50 = 1.68 nM
|
|
|
|
CP0518910
|
US9186360, 55
Show/Hide
|
C20H14F4N4O4S
|
1
|
| 1 |
IC50 = 2.15 nM
|
|
|
|
CP0518928
|
US9186360, 59
Show/Hide
|
C20H14F4N4O4S
|
1
|
| 1 |
IC50 = 2.21 nM
|
|
|
|
CP0254280
|
CHEMBL4870870
Show/Hide
|
C20H18ClN7O2
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0512072
|
US9186360, 61
Show/Hide
|
C21H16F4N4O4S
|
1
|
| 1 |
IC50 = 2.93 nM
|
|
|
|
CP0478207
|
US9186360, 71
Show/Hide
|
C21H16ClF3N4O4S
|
1
|
| 1 |
IC50 = 3.18 nM
|
|
|
|
CP0412586
|
US9186360, 75
Show/Hide
|
C24H24Cl2N4O5S
|
1
|
| 1 |
IC50 = 3.34 nM
|
|
|
|
CP0412592
|
US9186360, 56
Show/Hide
|
C22H17F5N4O4S
|
1
|
| 1 |
IC50 = 3.38 nM
|
|
|
|
CP0463403
|
US9186360, 60
Show/Hide
|
C21H15ClF4N4O5S
|
1
|
| 1 |
IC50 = 3.54 nM
|
|
|
|
CP0482711
|
US9186360, 62
Show/Hide
|
C25H26F2N4O5S
|
1
|
| 1 |
IC50 = 3.63 nM
|
|
|
|
CP0412575
|
US9186360, 49
Show/Hide
|
C23H19F5N4O4S2
|
1
|
| 1 |
IC50 = 3.98 nM
|
|
|
|
CP0516825
|
US9186360, 76
Show/Hide
|
C21H15F5N4O4S
|
1
|
| 1 |
IC50 = 4.02 nM
|
|
|
|
CP0512071
|
US9186360, 72
Show/Hide
|
C21H15F5N4O4S
|
1
|
| 1 |
IC50 = 4.16 nM
|
|
|
|
CP0478209
|
US9186360, 83
Show/Hide
|
C19H13F4N5O3S2
|
1
|
| 1 |
IC50 = 4.4 nM
|
|
|
|
CP0544901
|
US9186360, 64
Show/Hide
|
C21H15F5N4O4S
|
1
|
| 1 |
IC50 = 4.52 nM
|
|
|
|
CP0470699
|
US9186360, 68
Show/Hide
|
C21H16F4N4O5S
|
1
|
| 1 |
IC50 = 4.84 nM
|
|
|
|
CP0536196
|
US9186360, 99
Show/Hide
|
C20H13ClF4N4O4S
|
1
|
| 1 |
IC50 = 5.06 nM
|
|
|
|
CP0518943
|
US9186360, 100
Show/Hide
|
C20H13ClF4N4O4S
|
1
|
| 1 |
IC50 = 5.15 nM
|
|
|
|
CP0478208
|
US9186360, 79
Show/Hide
|
C19H13F4N5O3S2
|
1
|
| 1 |
IC50 = 5.29 nM
|
|
|
|
CP0518929
|
US9186360, 74
Show/Hide
|
C22H18ClF3N4O5S
|
1
|
| 1 |
IC50 = 5.29 nM
|
|
|
|
CP0544902
|
US9186360, 84
Show/Hide
|
C19H12F5N5O3S2
|
1
|
| 1 |
IC50 = 5.35 nM
|
|
|
|
CP0483920
|
US9186360, 33
Show/Hide
|
C22H15F5N4O3S
|
1
|
| 1 |
IC50 = 5.37 nM
|
|
|
|
CP0413536
|
US9186360, 77
Show/Hide
|
C19H12F5N5O3S2
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0262006
|
4-[3-(3-methoxypropoxy)phenyl]-2-sulfanylidene-3,4-dihydro-1H-indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C21H20N2O3S
|
1
|
| 1 |
IC50 = 5.61 nM
|
|
|
|
CP0479347
|
US9186360, 32
Show/Hide
|
C23H17F5N4O4S
|
1
|
| 1 |
IC50 = 5.96 nM
|
|
|
|
CP0548934
|
US9186360, 80
Show/Hide
|
C19H13ClF3N5O4S2
|
1
|
| 1 |
IC50 = 6.28 nM
|
|
|
|
CP0412618
|
US9186360, 28
Show/Hide
|
C22H15F5N4O3S
|
1
|
| 1 |
IC50 = 6.49 nM
|
|
|
|
CP0482710
|
US9186360, 65
Show/Hide
|
C21H16F4N4O4S
|
1
|
| 1 |
IC50 = 6.65 nM
|
|
|
|
CP0485488
|
US9186360, 81
Show/Hide
|
C19H13F4N5O3S2
|
1
|
| 1 |
IC50 = 6.74 nM
|
|
|
|
CP0441106
|
US9186360, 86
Show/Hide
|
C22H16F5N5O4S
|
1
|
| 1 |
IC50 = 6.91 nM
|
|
|
|
CP0413540
|
US9186360, 69
Show/Hide
|
C21H16F4N4O4S
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0480209
|
3-[3-(4- chlorophenyl)cyclobutyl]-5- [(7-methyl-6-oxo-purin-1- yl)methyl]-1,3,4-oxadiazol- 2-one
Show/Hide
|
C19H17ClN6O3
|
1
|
| 1 |
IC50 = 7.4 nM
|
|
|
|
CP0549962
|
US9186360, 104
Show/Hide
|
C20H12ClF5N4O4S
|
1
|
| 1 |
IC50 = 7.58 nM
|
|
|
|
CP0519514
|
US9186360, 102
Show/Hide
|
C20H13ClF4N4O5S
|
1
|
| 1 |
IC50 = 7.67 nM
|
|
|
|
CP0412587
|
US9186360, 82
Show/Hide
|
C19H13F4N5O4S2
|
1
|
| 1 |
IC50 = 8.04 nM
|
|
|
|
CP0539123
|
(2S,4R,5S)-4-fluoro-1-(4-fluorophenyl)sulfonyl-N-[[5-fluoro-2-[2-(trifluoromethyl)pyrimidin-5-yl]pyridin-4-yl]methyl]-5-methylpyrrolidine-2-carboxamide
Show/Hide
|
C23H19F6N5O3S
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0419512
|
US9186360, 73
Show/Hide
|
C21H16ClF3N4O5S
|
1
|
| 1 |
IC50 = 8.54 nM
|
|
|
|
CP0402704
|
US9186360, 85
Show/Hide
|
C21H15F4N5O3S
|
1
|
| 1 |
IC50 = 8.92 nM
|
|
|
|
CP0478206
|
US9186360, 63
Show/Hide
|
C21H16ClF3N4O5S
|
1
|
| 1 |
IC50 = 9.04 nM
|
|
|
|
CP0419514
|
US9186360, 101
Show/Hide
|
C20H12ClF5N4O4S
|
1
|
| 1 |
IC50 = 10.1 nM
|
|
|
|
CP0499846
|
US9186360, 78
Show/Hide
|
C19H13F4N5O3S2
|
1
|
| 1 |
IC50 = 10.57 nM
|
|
|
|
CP0441115
|
US9186360, 41
Show/Hide
|
C20H16F4N6O4S
|
1
|
| 1 |
IC50 = 11.04 nM
|
|
|
|
CP0495055
|
US9186360, 29
Show/Hide
|
C22H16F4N4O4S
|
1
|
| 1 |
IC50 = 11.38 nM
|
|
|
|
CP0490192
|
US9186360, 88
Show/Hide
|
C21H15F4N5O4S
|
1
|
| 1 |
IC50 = 11.45 nM
|
|
|
|
CP0413535
|
US9186360, 58
Show/Hide
|
C20H14F4N4O4S
|
1
|
| 1 |
IC50 = 11.88 nM
|
|
|
|
CP0479349
|
US9186360, 37
Show/Hide
|
C23H24Cl2N6O4S
|
1
|
| 1 |
IC50 = 12.26 nM
|
|
|
|
CP0412578
|
US9186360, 70
Show/Hide
|
C21H16F4N4O5S
|
1
|
| 1 |
IC50 = 12.57 nM
|
|
|
|
CP0412582
|
US9186360, 18
Show/Hide
|
C22H16F4N4O3S
|
1
|
| 1 |
IC50 = 13.38 nM
|
|
|
|
CP0470141
|
US9186360, 67
Show/Hide
|
C21H16F4N4O4S
|
1
|
| 1 |
IC50 = 13.59 nM
|
|
|
|
CP0472819
|
US9186360, 38
Show/Hide
|
C20H16F4N6O3S
|
1
|
| 1 |
IC50 = 15.92 nM
|
|
|
|
CP0479354
|
US9186360, 50
Show/Hide
|
C22H18F4N4O3S2
|
1
|
| 1 |
IC50 = 16.73 nM
|
|
|
|
CP0470143
|
US9186360, 92
Show/Hide
|
C19H12F5N5O4S
|
1
|
| 1 |
IC50 = 17.08 nM
|
|
|
|
CP0419511
|
US9186360, 31
Show/Hide
|
C22H15F5N4O3S
|
1
|
| 1 |
IC50 = 17.3 nM
|
|
|
|
CP0478205
|
US9186360, 54
Show/Hide
|
C20H14F4N4O4S
|
1
|
| 1 |
IC50 = 17.74 nM
|
|
|
|
CP0482713
|
US9186360, 35
Show/Hide
|
C22H18Cl2F3N5O4S
|
1
|
| 1 |
IC50 = 18.05 nM
|
|
|
|
CP0463405
|
US9186360, 48
Show/Hide
|
C22H18F4N4O4S2
|
1
|
| 1 |
IC50 = 18.12 nM
|
|
|
|
CP0516826
|
US9186360, 53
Show/Hide
|
C23H22F2N4O5S
|
1
|
| 1 |
IC50 = 18.2 nM
|
|
|
|
CP0413541
|
US9186360, 87
Show/Hide
|
C21H14F5N5O3S
|
1
|
| 1 |
IC50 = 19.32 nM
|
|
|
|
CP0557690
|
(R)-3-(2-(4-chlorophenyl)- 2-fluoroethyl)-5-((7-methyl- 6-oxo-6H-purin-1(7H)- yl)methyl)-1,3,4-oxadiazol- 2(3H)-one
Show/Hide
|
C17H14ClFN6O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0419516
|
US9186360, 20
Show/Hide
|
C22H16F4N4O3S
|
1
|
| 1 |
IC50 = 20.09 nM
|
|
|
|
CP0913418
|
US9186360, 97
Show/Hide
|
C26H24F5N5O5S2
|
1
|
| 1 |
IC50 = 21.91 nM
|
|
|
|
CP0441112
|
US9186360, 19
Show/Hide
|
C22H16F4N4O3S
|
1
|
| 1 |
IC50 = 26.13 nM
|
|
|
|
CP0412619
|
US9186360, 39
Show/Hide
|
C20H17F3N6O3S
|
1
|
| 1 |
IC50 = 26.56 nM
|
|
|
|
CP0531442
|
US9186360, 103
Show/Hide
|
C20H13ClF4N4O5S
|
1
|
| 1 |
IC50 = 27.41 nM
|
|
|
|
CP0470719
|
US9186360, 47
Show/Hide
|
C20H16Cl2N4O3S2
|
1
|
| 1 |
IC50 = 33.61 nM
|
|
|
|
CP0412583
|
US9186360, 30
Show/Hide
|
C22H17ClF2N4O4S
|
1
|
| 1 |
IC50 = 34.03 nM
|
|
|
|
CP0478201
|
US9186360, 34
Show/Hide
|
C20H16F3N5O4S
|
1
|
| 1 |
IC50 = 38.46 nM
|
|
|
|
CP0521618
|
US9186360, 46
Show/Hide
|
C23H20F4N4O3S2
|
1
|
| 1 |
IC50 = 41.31 nM
|
|
|
|
CP0441113
|
US9186360, 23
Show/Hide
|
C25H26N4O4S
|
1
|
| 1 |
IC50 = 43.93 nM
|
|
|
|
CP0412588
|
US9186360, 11
Show/Hide
|
C22H17F3N4O3S
|
1
|
| 1 |
IC50 = 46.27 nM
|
|
|
|
CP0489890
|
US9186360, 10
Show/Hide
|
C27H28N4O3S
|
1
|
| 1 |
IC50 = 46.74 nM
|
|
|
|
CP0490193
|
US9186360, 16
Show/Hide
|
C22H17F3N4O3S
|
1
|
| 1 |
IC50 = 47.37 nM
|
|
|
|
CP0495054
|
US9186360, 26
Show/Hide
|
C22H17F3N4O4S
|
1
|
| 1 |
IC50 = 47.91 nM
|
|
|
|
CP0412557
|
US9186360, 21
Show/Hide
|
C22H16ClF3N4O3S
|
1
|
| 1 |
IC50 = 48.18 nM
|
|
|
|
CP0519543
|
US9186360, 13
Show/Hide
|
C21H16F2N4O3S
|
1
|
| 1 |
IC50 = 48.21 nM
|
|
|
|
CP0479348
|
US9186360, 36
Show/Hide
|
C20H15F4N5O3S
|
1
|
| 1 |
IC50 = 49.92 nM
|
|
|
|
CP0463398
|
US9186360, 12
Show/Hide
|
C25H26N4O3S
|
1
|
| 1 |
IC50 = 51.68 nM
|
|
|
|
CP0463399
|
US9186360, 15
Show/Hide
|
C21H16ClFN4O3S
|
1
|
| 1 |
IC50 = 53.57 nM
|
|
|
|
CP0499890
|
US9186360, 98
Show/Hide
|
C24H21ClF3N5O7S
|
1
|
| 1 |
IC50 = 54.29 nM
|
|
|
|
CP0512093
|
US9186360, 8
Show/Hide
|
C21H18ClN5O3
|
1
|
| 1 |
IC50 = 55.02 nM
|
|
|
|
CP0412617
|
US9186360, 17
Show/Hide
|
C23H22N4O3S
|
1
|
| 1 |
IC50 = 56.02 nM
|
|
|
|
CP0441114
|
US9186360, 25
Show/Hide
|
C21H16ClFN4O3S
|
1
|
| 1 |
IC50 = 58.55 nM
|
|
|
|
CP0463400
|
US9186360, 16
Show/Hide
|
C22H18F3N5O3
|
1
|
| 1 |
IC50 = 58.94 nM
|
|
|
|
CP0412589
|
US9186360, 14
Show/Hide
|
C24H24N4O3S
|
1
|
| 1 |
IC50 = 60.42 nM
|
|
|
|
CP0254278
|
(2S,4R,5S)-4-fluoro-1-(4-fluorophenyl)sulfonyl-5-methyl-N-[[6-[2-(trifluoromethyl)pyrimidin-5-yl]pyrimidin-4-yl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C22H19F5N6O3S
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0423872
|
US9186360, 27
Show/Hide
|
C21H16F2N4O3S
|
1
|
| 1 |
IC50 = 65.45 nM
|
|
|
|
CP0512088
|
US9186360, 5
Show/Hide
|
C21H17IN4O3S
|
1
|
| 1 |
IC50 = 66.28 nM
|
|
|
|
CP0463397
|
US9186360, 3
Show/Hide
|
C21H17BrN4O3S
|
1
|
| 1 |
IC50 = 73.35 nM
|
|
|
|
CP0412454
|
US9186360, 22
Show/Hide
|
C26H28N4O4S
|
1
|
| 1 |
IC50 = 79.77 nM
|
|
|
|
CP0441108
|
US9186360, 95
Show/Hide
|
C27H27ClF3N5O7S
|
1
|
| 1 |
IC50 = 88.5 nM
|
|
|
|
CP0419515
|
US9186360, 6
Show/Hide
|
C22H20N4O3S
|
1
|
| 1 |
IC50 = 97.42 nM
|
|
|
|
CP0441110
|
US9186360, 4
Show/Hide
|
C21H16Cl2N4O3S
|
1
|
| 1 |
IC50 = 98.32 nM
|
|
|
|
CP0019489
|
US9108905, 1
Show/Hide
|
C12H14FNO
|
1
|
| 1 |
IC50 = 98.44 nM
|
|
|
|
CP0441111
|
US9186360, 9
Show/Hide
|
C21H17ClN4O3S
|
1
|
| 1 |
IC50 = 102.5 nM
|
|
|
|
CP0857140
|
rac-1,2,3,4-Tetrahydro-4-(3-methoxyphenyl)-2-thioxo-5H-indeno[1,2-d]pyrimidin-5-one
Show/Hide
|
C18H14N2O2S
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0402705
|
US9186360, 24
Show/Hide
|
C21H16ClFN4O3S
|
1
|
| 1 |
IC50 = 138.1 nM
|
|
|
|
CP0545729
|
(2S,4R,5S)-4-fluoro-1-(4-fluorophenyl)sulfonyl-5-methyl-N-[[6-[6-(trifluoromethyl)pyridin-3-yl]pyrimidin-4-yl]methyl]pyrrolidine-2-carboxamide
Show/Hide
|
C23H20F5N5O3S
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0518944
|
US9186360, 2
Show/Hide
|
C23H25N7O2S
|
1
|
| 1 |
IC50 = 381.8 nM
|
|
|
|
CP0489889
|
US9186360, 96
Show/Hide
|
C21H16F5N4O7PS2
|
1
|
| 1 |
IC50 = 559.3 nM
|
|
|
|
CP0441109
|
US9186360, 1
Show/Hide
|
C19H16BrN7O2S
|
1
|
| 1 |
IC50 = 920.9 nM
|
|
|
|
CP0516824
|
US9186360, 93
Show/Hide
|
C22H19ClF3N4O9PS
|
1
|
| 1 |
IC50 = 1180 nM
|
|
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CP0419513
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US9186360, 94
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C21H18F5N6O7PS
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1
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| 1 |
IC50 = 1580 nM
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CP0862489
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4-(4-chlorophenyl)-3-methylbut-3-en-2-one oxime
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C11H12ClNO
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1
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| 1 |
IC50 = 3100 nM
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