Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT02131 , Adenosine receptor A2b
Gene Name ADORA2B
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P29276
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT02131
 
Compound ID Compound Name Compound Formula
CP0415983
3-ethyl-6-(4-hydroxypiperidine-1-carbonyl)-5-methyl-1-(3,3,3-trifluoropropyl)thieno[2,3-d]pyrimidine-2,4-dione
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C18H22F3N3O4S
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0391881
N-[2-(2,2-difluoro-4,6,10,12-tetramethyl-3-aza-1-azonia-2-boranuidatricyclo[7.3.0.03,7]dodeca-1(12),4,6,8,10-pentaen-8-yl)ethyl]-2-[4-(2,6-dioxo-1-propyl-3,7-dihydropurin-8-yl)phenoxy]acetamide
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C31H34BF2N7O4
 1
1
Ki = 0.18 nM
   TI
   LI
   LO
   TS
CP0398710
1,3-dibutyl-9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C30H46N6O3
 1
1
Ki = 1100 nM
   TI
   LI
   LO
   TS
CP0065233
4-(2,6-Dioxo-1-propyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzenesulfonic acid
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C14H14N4O5S
 1
1
Ki = 3140 nM
   TI
   LI
   LO
   TS
CP0043620
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
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C8H10N4O2
 1
1
Ki = 30000 nM
   TI
   LI
   LO
   TS
CP0398703
1,3-dipropyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C26H36N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0398705
1,3-dibutyl-9-[4-[2-(diethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C28H42N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0398706
1,3-dibutyl-9-[4-(2-piperidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C29H42N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0408997
1,3-diethyl-9-[2-(4-hydroxyphenyl)ethyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C20H25N5O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0420550
1,3-dibutyl-9-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C28H40N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0450331
9-[2-[4-[2-(diethylamino)ethoxy]phenyl]ethyl]-1,3-dimethyl-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C24H34N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS
CP0473554
1,3-dibutyl-9-[4-[2-(dimethylamino)ethoxy]phenyl]-7,8-dihydro-6H-purino[7,8-a]pyrimidine-2,4-dione
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C26H38N6O3
 1
1
Ki > 1000 nM
   TI
   LI
   LO
   TS