| Compound ID |
Compound Name |
Compound Formula |
|
CP0534897
|
3-amino-6-bromo-N-[(2R)-3,3,3-trifluoro-2-hydroxypropyl]-5-(trifluoromethyl)pyridine-2-carboxamide
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|
C10H8BrF6N3O2
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0578912
|
US10117858, Example 16
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|
C12H10F9N3O2
|
1
|
| 1 |
EC50 = 9 nM
|
|
|
|
CP0532737
|
3-amino-6-bromo-N-[3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]-5-(trifluoromethyl)pyridine-2-carboxamide
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|
C11H7BrF9N3O2
|
1
|
| 1 |
EC50 = 10 nM
|
|
|
|
CP0532736
|
3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid ((S)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide
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|
C11H10BrF6N3O2
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0542524
|
3-amino-6-ethoxy-N-[(2S)-3,3,3-trifluoro-2-hydroxy-2-methylpropyl]-5-(trifluoromethyl)pyridine-2-carboxamide
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|
C13H15F6N3O3
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0568768
|
3-amino-6-bromo-N-[(2S)-3,3,3-trifluoro-2-hydroxypropyl]-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C10H8BrF6N3O2
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
|
CP0551216
|
3-Amino-6-bromo-5-trifluoromethyl-pyridine-2-carboxylic acid ((R)-3,3,3-trifluoro-2-hydroxy-2-methyl-propyl)-amide
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|
C11H10BrF6N3O2
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0570031
|
3-amino-6-bromo-5-(trifluoromethyl)-N-(3,3,3-trifluoropropyl)pyridine-2-carboxamide
Show/Hide
|
C10H8BrF6N3O
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0551217
|
US10117858, Example 5
Show/Hide
|
C12H13F6N3O3
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0567997
|
3-amino-6-bromo-N-(2-hydroxypropyl)-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C10H11BrF3N3O2
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0552444
|
3-amino-6-bromo-N-(2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C11H13BrF3N3O2
|
1
|
| 1 |
EC50 = 77 nM
|
|
|
|
CP0534898
|
methyl 2-amino-5-(furan-2-yl)-4-(trifluoromethyl)benzoate
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|
C13H10F3NO3
|
2
|
| 1 |
EC50 = 78 nM
|
|
|
| 2 |
EC50 = 920 nM
|
|
|
|
CP0568011
|
3-amino-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C11H11F6N3O2
|
1
|
| 1 |
EC50 = 229 nM
|
|
|
|
CP0567998
|
3-amino-6-methyl-N-(3,3,3-trifluoro-2-hydroxy-2-methylpropyl)-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C12H13F6N3O2
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0570033
|
methyl 2-amino-5-(1,3-oxazol-2-yl)-4-(trifluoromethyl)benzoate
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|
C12H9F3N2O3
|
1
|
| 1 |
EC50 = 240 nM
|
|
|
|
CP0569893
|
3-amino-6-bromo-N-methyl-5-(trifluoromethyl)pyridine-2-carboxamide
Show/Hide
|
C8H7BrF3N3O
|
1
|
| 1 |
EC50 = 250 nM
|
|
|
|
CP0577467
|
methyl 2-amino-5-pyridin-3-yl-4-(trifluoromethyl)benzoate
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|
C14H11F3N2O2
|
1
|
| 1 |
EC50 = 329 nM
|
|
|
|
CP0552445
|
methyl 2-amino-5-iodo-4-(trifluoromethyl)benzoate
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|
C9H7F3INO2
|
1
|
| 1 |
EC50 = 362 nM
|
|
|
|
CP0944923
|
2-(2-(1H-indol-3-yl)-N-methylacetamido)-N-(4-isopropylphenyl)-2-phenylacetamide
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|
C28H29N3O2
|
2
|
| 1 |
EC50 = 390 nM
|
|
|
| 2 |
EC50 = 1250 nM
|
|
|
|
CP0534890
|
methyl 2-amino-5-(oxolan-2-yl)-4-(trifluoromethyl)benzoate
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|
C13H14F3NO3
|
1
|
| 1 |
EC50 = 462 nM
|
|
|
|
CP0577853
|
2-amino-5-(furan-2-yl)-N-methyl-4-(trifluoromethyl)benzamide
Show/Hide
|
C13H11F3N2O2
|
1
|
| 1 |
EC50 = 1860 nM
|
|
|
|
CP0532733
|
methyl 2-amino-4-(trifluoromethyl)benzoate
Show/Hide
|
C9H8F3NO2
|
1
|
| 1 |
EC50 = 3780 nM
|
|
|
|
CP0542707
|
methyl 3-amino-6-(furan-2-yl)-5-(trifluoromethyl)pyridine-2-carboxylate
Show/Hide
|
C12H9F3N2O3
|
1
|
| 1 |
EC50 = 5310 nM
|
|
|
|
CP0571289
|
2-amino-5-(furan-2-yl)-4-(trifluoromethyl)benzoic acid
Show/Hide
|
C12H8F3NO3
|
1
|
| 1 |
EC50 = 5830 nM
|
|
|
|
CP0012708
|
5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
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|
C15H10O5
|
2
|
| 1 |
EC50 = 8200 nM
|
|
|
| 2 |
EC50 = 8480 nM
|
|
|
|
CP0532734
|
2-amino-5-(furan-2-yl)-N,N-dimethyl-4-(trifluoromethyl)benzamide
Show/Hide
|
C14H13F3N2O2
|
1
|
| 1 |
EC50 = 30000 nM
|
|
|
|
CP0578911
|
CHEBI:73244
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|
C8H9NO2
|
1
|
| 1 |
EC50 = 30000 nM
|
|
|
|
CP0456293
|
2,4-dimethylpyrido[1,2-a]pyrimidin-5-ium-3-olate
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|
C10H10N2O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0891699
|
(2S,3S,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-2H-pyrimido[2,1-a]isoquinolin-1-ium-2-carboxylate
Show/Hide
|
C15H16N2O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0921539
|
(2S,3R,4R)-3,4-dihydroxy-2,4-dimethyl-3,4-dihydro-2H-pyrimido[2,1-a]isoquinolin-1-ium-2-carboxylate
Show/Hide
|
C15H16N2O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0524493
|
2,4-dimethylpyrimido[2,1-a]isoquinolin-5-ium-3-olate
Show/Hide
|
C14H12N2O
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0002800
|
1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
Show/Hide
|
C23H28ClN3O5S
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
