Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01968 , Mitogen-activated protein kinase kinase kinase 9
Gene Name MAP3K9
Organism Homo sapiens, Human
Protein Classification Kinase
Uniprot ID P80192
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01968
 
Compound ID Compound Name Compound Formula
CP0353098
3-(2-hydroxyethyl)-20-(propan-2-yloxy)-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
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C27H26N2O3
 1
1
IC50 = 33 nM
   TI
   LI
   LO
   TS
CP0039413
CEP-1347
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C33H33N3O5S2
 1
1
IC50 = 72 nM
   TI
   LI
   LO
   TS
CP0123702
3-(2-hydroxyethyl)-20-methoxy-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
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C25H22N2O3
 1
1
IC50 = 127 nM
   TI
   LI
   LO
   TS
CP0211714
20-(propan-2-yloxy)-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
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C25H22N2O2
 1
1
IC50 = 196 nM
   TI
   LI
   LO
   TS
CP0264583
20-(cyclopentyloxy)-3-(2-hydroxyethyl)-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
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C29H28N2O3
 1
1
IC50 = 345 nM
   TI
   LI
   LO
   TS