Brief Information of the Compound and Protein
Compound Name
20-(propan-2-yloxy)-3,13-diazahexacyclo[14.8.0.0^{2,10}.0^{4,9}.0^{11,15}.0^{17,22}]tetracosa-1(16),2(10),4(9),5,7,11(15),17(22),18,20-nonaen-14-one
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PubChem ID
CID: 24971430
SID: 56429919
Canonical SMILES
CC(C)Oc1ccc-2c(CCc3c-2c2C(=O)NCc2c2c4ccccc4[nH]c32)c1
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Compound Formula C25H22N2O2
Compound Structure
Protein Name
Mitogen-activated protein kinase kinase kinase 9
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase MLK family
>
TKL protein kinase MLK subfamily
Uniprot ID
P80192
Gene Name
MAP3K9
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 196 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 66 nM