| Compound ID |
Compound Name |
Compound Formula |
|
CP0011420
|
5-(4-acetyl-1,4-diazepan-1-yl)-N-[5-(4-methoxyphenyl)-1H-pyrazol-3-yl]pentanamide
Show/Hide
|
C22H31N5O3
|
1
|
| 1 |
EC50 = 3000 nM
|
|
|
|
CP0005767
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1S,2R)-2-methylcyclopropyl]methanone
Show/Hide
|
C12H20N2O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0000360
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1S,2R)-2-fluorocyclopropyl]methanone
Show/Hide
|
C11H17FN2O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0003306
|
cyclopropyl(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0000331
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1R,2R)-2-methylcyclopropyl]methanone
Show/Hide
|
C12H20N2O
|
1
|
| 1 |
Ki = 30 nM
|
|
|
|
CP0000919
|
cyclopropyl-[(1R,5S)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone
Show/Hide
|
C10H16N2O
|
1
|
| 1 |
Ki = 40 nM
|
|
|
|
CP0000353
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1R,2S)-2-methylcyclopropyl]methanone
Show/Hide
|
C12H20N2O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0001415
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1R,2R)-2-fluorocyclopropyl]methanone
Show/Hide
|
C11H17FN2O
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0006775
|
[(3aR,6aS)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrol-5-yl]-cyclopropylmethanone
Show/Hide
|
C11H17NO
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0009419
|
cyclopropyl-[(1S,5R)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone
Show/Hide
|
C10H16N2O
|
1
|
| 1 |
Ki = 210 nM
|
|
|
|
CP0002644
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1S,2S)-2-methylcyclopropyl]methanone
Show/Hide
|
C12H20N2O
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0006147
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1S,2S)-2-fluorocyclopropyl]methanone
Show/Hide
|
C11H17FN2O
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0633535
|
3-(Cyclopropylcarbonyl)-3,6-diazabicyclo[3.2.1]octane
Show/Hide
|
C10H16N2O
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0001419
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1S,2R)-2-methylcyclopropyl]methanone
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0000356
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-[(1R,2S)-2-fluorocyclopropyl]methanone
Show/Hide
|
C11H17FN2O
|
1
|
| 1 |
Ki = 400 nM
|
|
|
|
CP0002192
|
[(1R,5S)-3,6-diazabicyclo[3.2.1]octan-3-yl]-(furan-2-yl)methanone
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
Ki = 560 nM
|
|
|
|
CP0001523
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(cyclopropyl)methanone
Show/Hide
|
C10H16N2O
|
1
|
| 1 |
Ki = 840 nM
|
|
|
|
CP0000357
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1S,2R)-2-fluorocyclopropyl]methanone
Show/Hide
|
C10H15FN2O
|
1
|
| 1 |
Ki = 990 nM
|
|
|
|
CP0002199
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(5-fluorofuran-2-yl)methanone
Show/Hide
|
C11H13FN2O2
|
1
|
| 1 |
Ki = 1200 nM
|
|
|
|
CP0003305
|
3,6-diazabicyclo[3.2.1]octan-3-yl(pyridin-4-yl)methanone
Show/Hide
|
C12H15N3O
|
1
|
| 1 |
Ki = 1300 nM
|
|
|
|
CP0000358
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1R,2R)-2-fluorocyclopropyl]methanone
Show/Hide
|
C10H15FN2O
|
1
|
| 1 |
Ki = 1400 nM
|
|
|
|
CP0006364
|
[(1R,5S)-3,6-diazabicyclo[3.2.1]octan-3-yl]-(5-fluorofuran-2-yl)methanone
Show/Hide
|
C11H13FN2O2
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0002207
|
1-(3,7-diazabicyclo[3.3.1]nonan-3-yl)propan-1-one
Show/Hide
|
C10H18N2O
|
1
|
| 1 |
Ki = 1600 nM
|
|
|
|
CP0000361
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1R,2R)-2-methylcyclopropyl]methanone
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
Ki = 1900 nM
|
|
|
|
CP0002190
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(3-chlorofuran-2-yl)methanone
Show/Hide
|
C11H13ClN2O2
|
1
|
| 1 |
Ki = 2600 nM
|
|
|
|
CP0002208
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1R,2S)-2-fluorocyclopropyl]methanone
Show/Hide
|
C10H15FN2O
|
1
|
| 1 |
Ki = 2700 nM
|
|
|
|
CP0000063
|
CAS_29790-52-1
Show/Hide
|
C10H14N2
|
1
|
| 1 |
Ki = 3000 nM
|
|
|
|
CP0002209
|
1-(3,7-diazabicyclo[3.3.1]nonan-3-yl)ethanone
Show/Hide
|
C9H16N2O
|
1
|
| 1 |
Ki = 3300 nM
|
|
|
|
CP0002204
|
[(3aR,6aS)-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrol-5-yl]-(furan-2-yl)methanone
Show/Hide
|
C12H15NO2
|
1
|
| 1 |
Ki = 3400 nM
|
|
|
|
CP0000922
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(3-methylfuran-2-yl)methanone
Show/Hide
|
C12H16N2O2
|
1
|
| 1 |
Ki = 3700 nM
|
|
|
|
CP0002206
|
1-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl)propan-1-one
Show/Hide
|
C9H16N2O
|
1
|
| 1 |
Ki = 4000 nM
|
|
|
|
CP0002203
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1R,2S)-2-methylcyclopropyl]methanone
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
Ki = 4500 nM
|
|
|
|
CP0002188
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-bromofuran-2-yl)methanone
Show/Hide
|
C11H13BrN2O2
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0002197
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-(5-fluorofuran-2-yl)methanone
Show/Hide
|
C12H15FN2O2
|
1
|
| 1 |
Ki = 4700 nM
|
|
|
|
CP0002200
|
[(1S,5R)-3,6-diazabicyclo[3.2.1]octan-3-yl]-(furan-2-yl)methanone
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
Ki = 5500 nM
|
|
|
|
CP0000921
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-methyl-1,3-oxazol-5-yl)methanone
Show/Hide
|
C11H15N3O2
|
1
|
| 1 |
Ki = 5900 nM
|
|
|
|
CP0002194
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(furan-2-yl)methanone
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
Ki = 5900 nM
|
|
|
|
CP0001522
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(3-bromofuran-2-yl)methanone
Show/Hide
|
C11H13BrN2O2
|
1
|
| 1 |
Ki = 6300 nM
|
|
|
|
CP0000348
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(5-chlorofuran-2-yl)methanone
Show/Hide
|
C11H13ClN2O2
|
1
|
| 1 |
Ki = 6700 nM
|
|
|
|
CP0002205
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1S,2S)-2-fluorocyclopropyl]methanone
Show/Hide
|
C10H15FN2O
|
1
|
| 1 |
Ki = 6900 nM
|
|
|
|
CP0001525
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(1,3-oxazol-5-yl)methanone
Show/Hide
|
C10H13N3O2
|
1
|
| 1 |
Ki = 7600 nM
|
|
|
|
CP0633962
|
3-(2-Furoyl)-3,6-diazabicyclo[3.2.1]octane
Show/Hide
|
C11H14N2O2
|
1
|
| 1 |
Ki = 7800 nM
|
|
|
|
CP0001674
|
(5-bromofuran-2-yl)-[(1S,5R)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone
Show/Hide
|
C11H13BrN2O2
|
1
|
| 1 |
Ki = 8200 nM
|
|
|
|
CP0002183
|
3,7-diazabicyclo[3.3.1]nonan-3-yl(furan-2-yl)methanone
Show/Hide
|
C12H16N2O2
|
1
|
| 1 |
Ki = 8200 nM
|
|
|
|
CP0002198
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(5-methylfuran-2-yl)methanone
Show/Hide
|
C12H16N2O2
|
1
|
| 1 |
Ki = 8200 nM
|
|
|
|
CP0000917
|
5-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)furan-3-carbonitrile
Show/Hide
|
C12H13N3O2
|
1
|
| 1 |
Ki = 8600 nM
|
|
|
|
CP0001521
|
2-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)furan-3-carbonitrile
Show/Hide
|
C12H13N3O2
|
1
|
| 1 |
Ki = 8800 nM
|
|
|
|
CP0000896
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-(3-fluorofuran-2-yl)methanone
Show/Hide
|
C12H15FN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0000918
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-chlorofuran-2-yl)methanone
Show/Hide
|
C11H13ClN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0000920
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(3-fluorofuran-2-yl)methanone
Show/Hide
|
C11H13FN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001520
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(5-bromofuran-2-yl)methanone
Show/Hide
|
C11H13BrN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001526
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-(5-methylfuran-2-yl)methanone
Show/Hide
|
C13H18N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001527
|
5-(3,7-diazabicyclo[3.3.1]nonane-3-carbonyl)furan-3-carbonitrile
Show/Hide
|
C13H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001528
|
(3-bromofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15BrN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001533
|
2-(3,7-diazabicyclo[3.3.1]nonane-3-carbonyl)furan-3-carbonitrile
Show/Hide
|
C13H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0001676
|
5-(2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrole-5-carbonyl)furan-2-carbonitrile
Show/Hide
|
C12H13N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002103
|
5-(3,7-diazabicyclo[3.3.1]nonane-3-carbonyl)furan-2-carbonitrile
Show/Hide
|
C13H15N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002104
|
(4-chlorofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15ClN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002186
|
(5-bromofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15BrN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002187
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-(4-fluorofuran-2-yl)methanone
Show/Hide
|
C12H15FN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002191
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-fluorofuran-2-yl)methanone
Show/Hide
|
C11H13FN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002196
|
3,7-diazabicyclo[3.3.1]nonan-3-yl-(3-methylfuran-2-yl)methanone
Show/Hide
|
C13H18N2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0003271
|
(3-chlorofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15ClN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0005207
|
3,7-diazabicyclo[3.3.1]nonan-3-yl(pyridin-4-yl)methanone
Show/Hide
|
C13H17N3O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0005209
|
(4-bromofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15BrN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0005645
|
(5-chlorofuran-2-yl)-(3,7-diazabicyclo[3.3.1]nonan-3-yl)methanone
Show/Hide
|
C12H15ClN2O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0635072
|
endo-(1R,5S)-N-propyl-3-azabicyclo[3.3.1]nonane-7-carboxamide
Show/Hide
|
C12H22N2O
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0634124
|
endo-(1R,5S)-N-isopropyl-3-azabicyclo[3.3.1]nonane-7-carboxamide
Show/Hide
|
C12H22N2O
|
1
|
| 1 |
Ki = 11000 nM
|
|
|
|
CP0001649
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-phenoxyphenyl)methanone
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
|
CP0001417
|
CHEMBL3037929
Show/Hide
|
C9H15NO2
|
1
|
| 1 |
Ki = 13000 nM
|
|
|
|
CP0001675
|
(5-bromofuran-2-yl)-[(1R,5S)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone
Show/Hide
|
C11H13BrN2O2
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0002189
|
[(1S,5R)-3,6-diazabicyclo[3.2.1]octan-3-yl]-(5-fluorofuran-2-yl)methanone
Show/Hide
|
C11H13FN2O2
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0005208
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(1,3-oxazol-2-yl)methanone
Show/Hide
|
C10H13N3O2
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0009418
|
(5-chlorofuran-2-yl)-[(1R,5S)-3,6-diazabicyclo[3.2.1]octan-3-yl]methanone
Show/Hide
|
C11H13ClN2O2
|
1
|
| 1 |
Ki = 14000 nM
|
|
|
|
CP0001650
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(pyridin-4-yl)methanone
Show/Hide
|
C12H15N3O
|
1
|
| 1 |
Ki = 15000 nM
|
|
|
|
CP0634125
|
endo-(1R,5S)-3-azabicyclo[3.3.1]nonan-7-yl(furan-2-yl)methanone
Show/Hide
|
C13H17NO2
|
1
|
| 1 |
Ki = 15000 nM
|
|
|
|
CP0002195
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(1,2-oxazol-5-yl)methanone
Show/Hide
|
C10H13N3O2
|
1
|
| 1 |
Ki = 19000 nM
|
|
|
|
CP0001673
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(phenyl)methanone
Show/Hide
|
C13H16N2O
|
1
|
| 1 |
Ki = 20000 nM
|
|
|
|
CP0002185
|
2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(pyridin-3-yl)methanone
Show/Hide
|
C12H15N3O
|
1
|
| 1 |
Ki = 20000 nM
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CP0000354
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(3aR,6aS)-N-methyl-1,2,3,3a,4,5,6,6a-octahydrocyclopenta[c]pyrrole-5-carboxamide
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C9H16N2O
|
1
|
| 1 |
Ki = 27000 nM
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|
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CP0002184
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3,7-diazabicyclo[3.3.1]nonan-3-yl(phenyl)methanone
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C14H18N2O
|
1
|
| 1 |
Ki = 34000 nM
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|
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CP0001524
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(E)-4-(5-ethoxypyridin-3-yl)-N-methylbut-3-en-1-amine
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C12H18N2O
|
1
|
| 1 |
Ki = 71000 nM
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CP0000916
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2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(furan-3-yl)methanone
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C11H14N2O2
|
1
|
| 1 |
Ki = 100000 nM
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CP0001672
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3,7-diazabicyclo[3.3.1]nonan-3-yl-(4-methoxyphenyl)methanone
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C15H20N2O2
|
1
|
| 1 |
Ki = 100000 nM
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CP0002193
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2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-(4-methoxyphenyl)methanone
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|
C14H18N2O2
|
1
|
| 1 |
Ki = 100000 nM
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|
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CP0005712
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2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl(pyridin-2-yl)methanone
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|
C12H15N3O
|
1
|
| 1 |
Ki = 100000 nM
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|
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CP0002172
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2,3,3a,4,6,6a-hexahydro-1H-pyrrolo[3,4-c]pyrrol-5-yl-[(1S,2S)-2-methylcyclopropyl]methanone
Show/Hide
|
C11H18N2O
|
1
|
| 1 |
Ki = 100000 nM
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