Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01716 , Cholesteryl ester transfer protein
Gene Name CETP
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID P11597
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01716
 
Compound ID Compound Name Compound Formula
CP0071357
(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one
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C30H25F10NO3
 2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0554829
(4R,5S)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one
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C30H25F10NO3
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0455557
ethyl 4-[3-(N-(4-fluorophenyl)sulfonyl-3-phenoxyanilino)propanoylamino]benzoate
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C30H27FN2O6S
 1
1
IC50 = 150 nM
   TI
   LI
   LO
   TS
CP0519343
ethyl 4-[3-[N-[(4-fluorophenyl)methyl]-3-phenoxyanilino]propanoylamino]benzoate
   Show/Hide
C31H29FN2O4
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0487799
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[4-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-4-oxobutanoyl]oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
   Show/Hide
C49H69F3N2O7
 1
1
IC50 = 280 nM
   TI
   LI
   LO
   TS
CP0474177
ethyl 4-[4-[3-[N-[(4-fluorophenyl)methyl]-3-phenoxyanilino]propanoyl]piperazin-1-yl]benzoate
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C35H36FN3O4
 1
1
IC50 = 690 nM
   TI
   LI
   LO
   TS
CP0434885
ethyl 4-[3-(4-chloro-N-(4-fluorophenyl)sulfonyl-3-phenylanilino)propanoylamino]benzoate
   Show/Hide
C30H26ClFN2O5S
 1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS
CP0404512
ethyl 4-[3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanoylamino]benzoate
   Show/Hide
C25H23Cl2FN2O3
 1
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
CP0407626
ethyl 4-[3-(3-chloro-N-(4-fluorophenyl)sulfonyl-5-phenylanilino)propanoylamino]benzoate
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C30H26ClFN2O5S
 1
1
IC50 = 2300 nM
   TI
   LI
   LO
   TS
CP0404511
ethyl 4-[3-[4-chloro-N-[(4-fluorophenyl)methyl]-3-phenylanilino]propanoylamino]benzoate
   Show/Hide
C31H28ClFN2O3
 1
1
IC50 = 2700 nM
   TI
   LI
   LO
   TS
CP0400877
3-[N-[(4-fluorophenyl)methyl]-3-phenoxyanilino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one
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C33H34FN3O3
 1
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
CP0452627
ethyl 4-[4-[3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanoyl]piperazin-1-yl]benzoate
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C29H30Cl2FN3O3
 2
1
IC50 = 2800 nM
   TI
   LI
   LO
   TS
2
IC50 = 12400 nM
   TI
   LI
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CP0544749
ethyl 4-[4-[3-[4-chloro-N-[(4-fluorophenyl)methyl]-3-phenylanilino]propanoyl]piperazin-1-yl]benzoate
   Show/Hide
C35H35ClFN3O3
 1
1
IC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0559248
ethyl 4-[4-[3-[N-[(4-fluorophenyl)methyl]-3-phenylanilino]propanoyl]piperazin-1-yl]benzoate
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C35H36FN3O3
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0455558
ethyl 4-[3-[3-chloro-N-[(4-fluorophenyl)methyl]-5-phenylanilino]propanoylamino]benzoate
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C31H28ClFN2O3
 1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0400878
3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one
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C27H28Cl2FN3O2
 2
1
IC50 = 3500 nM
   TI
   LI
   LO
   TS
2
IC50 = 4900 nM
   TI
   LI
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   TS
CP0513256
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[5-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-5-oxopentanoyl]oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
   Show/Hide
C50H71F3N2O7
 1
1
IC50 = 3790 nM
   TI
   LI
   LO
   TS
CP0513257
(1S,2R,4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[3-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-3-oxopropanoyl]oxy-1,2,6a,6b,9,9,12a-heptamethyl-2,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydro-1H-picene-4a-carboxylic acid
   Show/Hide
C48H67F3N2O7
 1
1
IC50 = 4420 nM
   TI
   LI
   LO
   TS
CP0459568
3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]-1-(4-phenylpiperazin-1-yl)propan-1-one
   Show/Hide
C26H26Cl2FN3O
 1
1
IC50 = 5200 nM
   TI
   LI
   LO
   TS
CP0404513
ethyl 4-[3-[N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-3,4-dichloroanilino]propanoylamino]benzoate
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C27H22Cl2F6N2O3
 1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS
CP0429258
ethyl 4-[4-[3-[N-[(4-fluorophenyl)methyl]-4-phenoxyanilino]propanoyl]piperazin-1-yl]benzoate
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C35H36FN3O4
 1
1
IC50 = 6700 nM
   TI
   LI
   LO
   TS
CP0508987
3-[N-[(4-fluorophenyl)methyl]-3-phenylanilino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one
   Show/Hide
C33H34FN3O2
 1
1
IC50 = 7300 nM
   TI
   LI
   LO
   TS
CP0519344
4-[3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanoylamino]benzoic acid
   Show/Hide
C23H19Cl2FN2O3
 1
1
IC50 = 9100 nM
   TI
   LI
   LO
   TS
CP0544750
ethyl 4-[3-[3,4-dichloro-N-[[4-(trifluoromethyl)phenyl]methyl]anilino]propanoylamino]benzoate
   Show/Hide
C26H23Cl2F3N2O3
 1
1
IC50 = 9500 nM
   TI
   LI
   LO
   TS
CP0508989
N-cyclohexyl-3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanamide
   Show/Hide
C22H25Cl2FN2O
 1
1
IC50 = 10700 nM
   TI
   LI
   LO
   TS
CP0474087
3-[N-[(4-fluorophenyl)methyl]-3-phenylanilino]-1-(4-phenylpiperazin-1-yl)propan-1-one
   Show/Hide
C32H32FN3O
 1
1
IC50 = 11300 nM
   TI
   LI
   LO
   TS
CP0452602
3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]-1-(4-pyrimidin-2-ylpiperazin-1-yl)propan-1-one
   Show/Hide
C24H24Cl2FN5O
 1
1
IC50 = 11800 nM
   TI
   LI
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   TS
CP0509833
3-[4-bromo-N-[(4-fluorophenyl)methyl]-3-methylanilino]-1-(4-phenylpiperazin-1-yl)propan-1-one
   Show/Hide
C27H29BrFN3O
 1
1
IC50 = 13900 nM
   TI
   LI
   LO
   TS
CP0508990
3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]-1-morpholin-4-ylpropan-1-one
   Show/Hide
C20H21Cl2FN2O2
 1
1
IC50 = 14200 nM
   TI
   LI
   LO
   TS
CP0544724
ethyl 4-[3-[N-[(4-fluorophenyl)methyl]-4-phenylanilino]propanoylamino]benzoate
   Show/Hide
C31H29FN2O3
 1
1
IC50 = 16700 nM
   TI
   LI
   LO
   TS
CP0565770
ethyl 4-[4-[3-[3,4-dichloro-N-[[4-(trifluoromethyl)phenyl]methyl]anilino]propanoyl]piperazin-1-yl]benzoate
   Show/Hide
C30H30Cl2F3N3O3
 1
1
IC50 = 18200 nM
   TI
   LI
   LO
   TS
CP0400879
3-[4-chloro-3-ethyl-N-[(4-fluorophenyl)methyl]anilino]-1-(4-phenylpiperazin-1-yl)propan-1-one
   Show/Hide
C28H31ClFN3O
 1
1
IC50 = 19500 nM
   TI
   LI
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   TS
CP0559249
N-tert-butyl-3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanamide
   Show/Hide
C20H23Cl2FN2O
 1
1
IC50 = 29600 nM
   TI
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   LO
   TS
CP0508988
3-[4-chloro-N-[(4-fluorophenyl)methyl]-3-(trifluoromethyl)anilino]-1-(4-phenylpiperazin-1-yl)propan-1-one
   Show/Hide
C27H26ClF4N3O
 1
1
IC50 = 37800 nM
   TI
   LI
   LO
   TS
CP0545271
3-[N-[(4-fluorophenyl)methyl]-4-phenoxyanilino]-1-[4-(4-methoxyphenyl)piperazin-1-yl]propan-1-one
   Show/Hide
C33H34FN3O3
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0509842
N-butyl-N-(cyclopropylmethyl)-3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanamide
   Show/Hide
C24H29Cl2FN2O
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0559250
N-cyclopropyl-3-[3,4-dichloro-N-[(4-fluorophenyl)methyl]anilino]propanamide
   Show/Hide
C19H19Cl2FN2O
 1
1
IC50 > 50000 nM
   TI
   LI
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   TS
CP0476433
(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[4-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-4-oxobutanoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
   Show/Hide
C49H69F3N2O7
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0566930
(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[5-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-5-oxopentanoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
   Show/Hide
C50H71F3N2O7
 1
1
IC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0566931
(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[3-[[(2R,4S)-1-ethoxycarbonyl-2-ethyl-6-(trifluoromethyl)-3,4-dihydro-2H-quinolin-4-yl]amino]-3-oxopropanoyl]oxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid
   Show/Hide
C48H67F3N2O7
 1
1
IC50 > 50000 nM
   TI
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   TS