Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4S,5R)-5-[3,5-bis(trifluoromethyl)phenyl]-3-[[2-(4-fluoro-2-methoxy-5-propan-2-ylphenyl)-5-(trifluoromethyl)phenyl]methyl]-4-methyl-1,3-oxazolidin-2-one
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 PubChem ID
CID: 11556427
SID: 125299337
Canonical SMILES
COc1cc(F)c(cc1-c1ccc(cc1CN1[C@@H](C)[C@H](OC1=O)c1cc(cc(c1)C(F)(F)F)C(F)(F)F)C(F)(F)F)C(C)C
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Compound Formula C30H25F10NO3
Compound Structure
Protein Name
 Protein Info 
Cholesteryl ester transfer protein
Protein Classification
Ion channel
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Other ion channel
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Pore-forming toxins (proteins and peptides)
Uniprot ID
P11597
Gene Name
CETP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 40 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM
2 IC50 = 17.2 nM
3 IC50 = 18 nM
4 IC50 = 33.8 nM
5 IC50 = 36 nM
6 IC50 = 40 nM
7 IC50 = 45 nM
8 IC50 = 46 nM