Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01713 , Muscarinic acetylcholine receptor M3
Gene Name CHRM3
Organism Rattus norvegicus, Rat
Protein Classification Membrane receptor
Uniprot ID P08483
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01713
 
Compound ID Compound Name Compound Formula
CP0020189
6-acetoxy-8-azonia-bicyclo[3.2.1]octane
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C9H15NO2
 1
1
EC50 = 3.6 nM
   TI
   LI
   LO
   TS
CP0167696
2-acetoxypropyl(trimethyl)ammonium;chloride
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C8H18NO2+
 1
1
EC50 = 120 nM
   TI
   LI
   LO
   TS
CP0054630
((2S,4R,5S)-4-Hydroxy-5-methyl-tetrahydro-furan-2-ylmethyl)-trimethyl-ammonium
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C9H20NO2+
 1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CP0635477
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
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C6H15ClN2O2
 1
1
EC50 = 480 nM
   TI
   LI
   LO
   TS
CP0240069
N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
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C23H25F3N4O3S
 1
1
EC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0392293
ethyl 4-[(3R)-3-[(3-methoxybenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
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C21H31N3O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0392294
ethyl 4-[(3R)-3-(cyclohexanecarbonylamino)piperidin-1-yl]piperidine-1-carboxylate
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C20H35N3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0392296
ethyl 4-[(3R)-3-[(3,4-difluorobenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
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C20H27F2N3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0395354
ethyl 4-[(3R)-3-benzamidopiperidin-1-yl]piperidine-1-carboxylate
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C20H29N3O3
 2
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
2
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0395356
ethyl 4-[(3R)-3-[(4-methoxybenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
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C21H31N3O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0395357
ethyl 4-[(3R)-3-(cyclopentanecarbonylamino)piperidin-1-yl]piperidine-1-carboxylate
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C19H33N3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401139
ethyl 4-[(3R)-3-(thiophene-2-carbonylamino)piperidin-1-yl]piperidine-1-carboxylate
   Show/Hide
C18H27N3O3S
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0401143
ethyl 4-[(3R)-3-[(2-chlorobenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
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C20H28ClN3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0405953
ethyl 4-[(3R)-3-[(4-fluoro-2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
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C21H30FN3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0433236
ethyl 4-[(3R)-3-[(3-fluorobenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
   Show/Hide
C20H28FN3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0440402
ethyl 4-[(3R)-3-[(4-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
   Show/Hide
C21H31N3O3
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0168609
ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
   Show/Hide
C21H31N3O3
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0392295
4-[2-(o-toluoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester;hydrochloride
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C18H27N3O3
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0305211
1-(1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
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C25H32N4O
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0434320
4-(2-benzamidoethylamino)-1-piperidinecarboxylic acid ethyl ester;hydrochloride
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C17H25N3O3
 1
1
EC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0372786
N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]-3-cyclopentylpropanamide
   Show/Hide
C20H30ClN3O
 2
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
2
Ki = 74.8 nM
   TI
   LI
   LO
   TS
CP0395930
3-[3-fluoro-1-[1-[(2-methylphenyl)methyl]piperidin-4-yl]piperidin-4-yl]-1H-benzimidazol-2-one
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C25H31FN4O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0427051
3-[2-[1-[(2-methylphenyl)methyl]piperidin-4-yl]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-5-yl]-1H-benzimidazol-2-one
   Show/Hide
C27H34N4O
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0449745
ethyl 4-[(3R)-3-[[6-(trifluoromethyl)pyridine-3-carbonyl]amino]piperidin-1-yl]piperidine-1-carboxylate
   Show/Hide
C20H27F3N4O3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0564404
N-[4-[6-[[(2R)-6-(oxan-4-ylmethyl)-6-azaspiro[2.5]octan-2-yl]methylamino]pyridazin-3-yl]phenyl]acetamide
   Show/Hide
C26H35N5O2
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0384304
(1S,2S)-N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]-2-phenylcyclopropane-1-carboxamide
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C22H26ClN3O
 1
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
CP0317131
(9bS)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
   Show/Hide
C23H15ClF2N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0381587
1-(3,4-difluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
   Show/Hide
C23H16F2N2O2
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0433266
N-[3-chloro-4-(4-ethylpiperazin-1-yl)phenyl]-3-phenylpropanamide
   Show/Hide
C21H26ClN3O
 1
1
IC50 = 70000 nM
   TI
   LI
   LO
   TS
CP0460758
[(5R)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl] 2,2-diphenylpropanoate
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C22H25NO2
 1
1
Ki = 0.522 nM
   TI
   LI
   LO
   TS
CP0446133
[(5S)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl] 2,2-diphenylpropanoate
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C22H25NO2
 1
1
Ki = 0.533 nM
   TI
   LI
   LO
   TS
CP0109931
ATROPEN
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C17H23NO3
 1
1
Ki = 0.8 nM
   TI
   LI
   LO
   TS
CP0047913
ENDO-ATROPINE
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C17H23NO3
 1
1
Ki = 0.96 nM
   TI
   LI
   LO
   TS
CP0437001
[(6S)-2-methyl-2-azabicyclo[2.2.1]heptan-6-yl] 2,2-diphenylpropanoate
   Show/Hide
C22H25NO2
 1
1
Ki = 4.03 nM
   TI
   LI
   LO
   TS
CP0492387
[(6R)-2-methyl-2-azabicyclo[2.2.1]heptan-6-yl] 2,2-diphenylpropanoate
   Show/Hide
C22H25NO2
 1
1
Ki = 8.33 nM
   TI
   LI
   LO
   TS
CP0402077
[(5S)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl] acetate
   Show/Hide
C9H15NO2
 1
1
Ki = 12000 nM
   TI
   LI
   LO
   TS
CP0436349
[(6S)-2-benzyl-2-azabicyclo[2.2.1]heptan-6-yl] acetate
   Show/Hide
C15H19NO2
 1
1
Ki = 18800 nM
   TI
   LI
   LO
   TS
CP0372486
Acetic acid 2-benzyl-2-aza-bicyclo[2.2.1]hept-5-yl ester
   Show/Hide
C15H19NO2
 1
1
Ki = 26900 nM
   TI
   LI
   LO
   TS
CP0397293
[(5R)-2-methyl-2-azabicyclo[2.2.1]heptan-5-yl] acetate
   Show/Hide
C9H15NO2
 1
1
Ki = 27700 nM
   TI
   LI
   LO
   TS
CP0458717
Acetic acid 2-methyl-2-aza-bicyclo[2.2.1]hept-6-yl ester
   Show/Hide
C9H15NO2
 1
1
Ki = 28000 nM
   TI
   LI
   LO
   TS
CP0523951
[(6R)-2-benzyl-2-azabicyclo[2.2.1]heptan-6-yl] acetate
   Show/Hide
C15H19NO2
 1
1
Ki = 47600 nM
   TI
   LI
   LO
   TS