| Compound ID |
Compound Name |
Compound Formula |
|
CP0381832
|
3-(4-(5-(3-cyano-4-(1,1,1-trifluoropropan-2-yloxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H18F3N3O4
|
1
|
| 1 |
EC50 = 0.03 nM
|
|
|
|
CP0394075
|
3-(4-(5-(4-(S)-sec-butoxy-3-cyanophenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C23H23N3O4
|
1
|
| 1 |
EC50 = 0.07 nM
|
|
|
|
CP0372367
|
3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)propanoic acid
Show/Hide
|
C22H21F3N2O4
|
2
|
| 1 |
EC50 = 0.08 nM
|
|
|
| 2 |
EC50 = 0.09 nM
|
|
|
|
CP0394078
|
3-(4-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-3-yl}-3-methylphenyl)propanoic acid
Show/Hide
|
C22H21N3O4
|
2
|
| 1 |
EC50 = 0.08 nM
|
|
|
| 2 |
EC50 < 0.08 nM
|
|
|
|
CP0467328
|
3-(4-(5-(3-bromo-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21BrN2O4
|
1
|
| 1 |
EC50 < 0.08 nM
|
|
|
|
CP0390634
|
3-(4-(5-(5-chloro-6-(1,1,1-trifluoropropan-2-yloxy)pyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H17ClF3N3O4
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0421315
|
3-(4-(5-(3-cyano-4-(1,1,1,3,3,3-hexafluoropropan-2-yloxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H15F6N3O4
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0431227
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-pentan-3-ylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0440022
|
N-[(2S)-3-[2-ethyl-4-[5-[5-ethyl-6-(2-methylpropyl)pyridin-3-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0445533
|
N-[(2S)-3-[4-[5-(2-cyclopentylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H32N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0445536
|
N-[(2S)-3-[4-[5-(6-cyclopentyl-5-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0446792
|
N-[(2S)-3-[4-[5-(2-cyclobutyl-6-methylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H32N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0446796
|
US9617250, S-entiomer of Example 22 of D1
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0446801
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(5-methyl-6-propan-2-ylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0505145
|
N-[(2S)-3-[4-[5-(2-cyclobutyl-6-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 = 0.1 nM
|
|
|
|
CP0381831
|
3-(4-(5-(3-cyano-4-(2,2,2-trifluoroethoxy)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H16F3N3O4
|
1
|
| 1 |
EC50 = 0.11 nM
|
|
|
|
CP0409183
|
3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)butanoic acid
Show/Hide
|
C23H23F3N2O4
|
1
|
| 1 |
EC50 = 0.12 nM
|
|
|
|
CP0372160
|
[(2R)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H34NO5P
|
3
|
| 1 |
EC50 = 0.14 nM
|
|
|
| 2 |
EC50 = 0.68 nM
|
|
|
| 3 |
IC50 = 0.16 nM
|
|
|
|
CP0390653
|
3-(4-(5-(4-isopropoxy-3-methylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C22H24N2O4
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0408509
|
3-(4-(5-(3-chloro-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21ClN2O4
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0419852
|
1-(4-(5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazol-3-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H18F3N3O3S
|
2
|
| 1 |
EC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 8.3 nM
|
|
|
|
CP0390242
|
US9617250, Example 233 of D1
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0392887
|
N-[(2S)-3-[2-ethyl-4-[5-(2-ethyl-6-pentan-3-ylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H38N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0392888
|
BDBM50165434
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0392892
|
N-[(2S)-3-[4-[5-[5-(diethylamino)-4-methylpyridin-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H35N5O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0428791
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0440017
|
N-[(2S)-3-[4-[5-(6-cyclopentyl-5-ethylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H36N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0445534
|
N-[(2S)-3-[4-[5-(6-cyclopentyl-4-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0445535
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-5-(2-methylpropyl)pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0466516
|
N-[(2S)-3-[4-[5-(5-cyclopentyl-4-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0390335
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-methyl-6-propan-2-yloxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O6
|
1
|
| 1 |
EC50 = 0.2 nM
|
|
|
|
CP0906035
|
(1R,2R)-2-(4-(5-(4-isopropoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)cyclopropanecarboxylic acid
Show/Hide
|
C23H21F3N2O4
|
1
|
| 1 |
EC50 = 0.21 nM
|
|
|
|
CP0511183
|
1-[[4-[5-(4-propyl-3-pyridin-2-yl-1,2-oxazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C24H23N5O4
|
1
|
| 1 |
EC50 = 0.21 nM
|
|
|
|
CP0409760
|
1-[[4-[5-(4-butyl-5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H26N4O4
|
1
|
| 1 |
EC50 = 0.27 nM
|
|
|
|
CP0065324
|
1-[[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H17F3N4O4
|
2
|
| 1 |
EC50 = 0.27 nM
|
|
|
| 2 |
EC50 = 0.47 nM
|
|
|
|
CP0275274
|
[(2S)-2-amino-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H34NO5P
|
2
|
| 1 |
EC50 = 0.28 nM
|
|
|
| 2 |
IC50 = 0.28 nM
|
|
|
|
CP0463957
|
2-methyl-3-(3-methyl-4-{5-[4-(propan-2-yloxy)-3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)propanoic acid
Show/Hide
|
C23H23F3N2O4
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0047332
|
[2-azaniumyl-2-(hydroxymethyl)-4-(4-octylphenyl)butyl] hydrogen phosphate
Show/Hide
|
C19H34NO5P
|
4
|
| 1 |
EC50 = 0.3 nM
|
|
|
| 2 |
EC50 = 9.1 nM
|
|
|
| 3 |
EC50 = 14 nM
|
|
|
| 4 |
IC50 = 0.28 nM
|
|
|
|
CP0385153
|
3-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H31F3N2O3
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0465580
|
3-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-fluorophenyl]methylamino]propanoic acid
Show/Hide
|
C26H30F4N2O3
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0392889
|
US9617250, Example 57 of D1
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0392890
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-propan-2-ylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0440020
|
N-[(2S)-3-[4-[5-(2-cyclopentyl-6-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H36N4O5
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0446799
|
N-[(2S)-3-[4-[5-[6-(diethylamino)-5-ethylpyridin-3-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H37N5O5
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0459613
|
N-[(2S)-3-[4-[5-[5-[(dimethylamino)methyl]-4-ethylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H34N4O5S
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0420056
|
1-[[4-[5-[5-(2-methylpropyl)-4-propyl-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H28N4O4
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0469652
|
N-[(2S)-3-[4-[5-(2-cyclobutyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H32N4O6
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0531251
|
N-[(2S)-3-[2-ethyl-4-[5-[2-methoxy-6-(2-methylpropyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O6
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0534605
|
N-[(2S)-3-[4-[5-(2-cyclobutyloxy-6-methylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H32N4O6
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0570889
|
N-[(2S)-3-[4-[5-(6-cyclopentyl-5-methoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 0.3 nM
|
|
|
|
CP0856516
|
(S)-1-((6-(3-(4-fluorophenyl)-2-methylpropoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C26H31ClFNO3
|
1
|
| 1 |
EC50 = 0.37 nM
|
|
|
|
CP0499808
|
1-[[4-[5-[5-(2-methylpropyl)-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C21H21F3N4O4
|
1
|
| 1 |
EC50 = 0.39 nM
|
|
|
|
CP0381848
|
3-(4-(5-(4-ethoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H19F3N2O4
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0214241
|
1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C29H35F3N2O3
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0410679
|
3-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-cyclopropylphenyl]methylamino]propanoic acid
Show/Hide
|
C29H35F3N2O3
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0427262
|
3-[[2-bromo-4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H30BrF3N2O3
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0379600
|
3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C26H36O4S
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0392959
|
3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3,5,5-triethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C28H40O4S
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0443219
|
3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3-ethylspiro[6,7-dihydro-4H-2-benzothiophene-5,1'-cyclopentane]-1-yl)propan-1-one
Show/Hide
|
C28H38O4S
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0392961
|
US9617250, Example 101 of D1
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0440019
|
N-[(2S)-3-[2-ethyl-4-[5-[2-(ethylamino)-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H31N5O5
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0531252
|
N-[(2S)-3-[2-ethyl-4-[5-(2-methoxy-6-pentan-3-ylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O6
|
1
|
| 1 |
EC50 = 0.4 nM
|
|
|
|
CP0434248
|
3-(5-{5-[3-cyano-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-3-yl}-6-methylpyridin-2-yl)propanoic acid
Show/Hide
|
C21H20N4O4
|
1
|
| 1 |
EC50 = 0.44 nM
|
|
|
|
CP0391148
|
1-[[4-[5-(3-phenyl-4-propyl-1,2-oxazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H24N4O4
|
1
|
| 1 |
EC50 = 0.44 nM
|
|
|
|
CP0420053
|
1-[[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H24N4O4
|
1
|
| 1 |
EC50 = 0.44 nM
|
|
|
|
CP0394082
|
3-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
EC50 = 0.5 nM
|
|
|
|
CP0384362
|
1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H20F3NO3S
|
2
|
| 1 |
EC50 = 0.5 nM
|
|
|
| 2 |
IC50 = 1.2 nM
|
|
|
|
CP0379595
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N-[3-[4-[5-[3,5-dimethyl-4-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2,6-dimethylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C25H33N3O5S
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1
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| 1 |
EC50 = 0.5 nM
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CP0415715
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N-[3-[2,6-dimethyl-4-[3-oxo-3-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propyl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C27H37NO5S
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1
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| 1 |
EC50 = 0.5 nM
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CP0446797
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-6-(2-methylpropyl)pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C26H34N4O5
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1
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| 1 |
EC50 = 0.5 nM
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CP0177664
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-5-[[methyl(2-methylpropyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H38N4O5S
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1
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| 1 |
EC50 = 0.5 nM
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CP0568784
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N-[(2S)-3-[2-ethyl-4-[5-[4-ethyl-5-[[methyl(propyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H38N4O5S
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1
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| 1 |
EC50 = 0.5 nM
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CP0490503
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1-[[4-[5-[4-(1,1-difluoroethyl)-5-phenyl-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
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C24H20F2N4O4
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1
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| 1 |
EC50 = 0.54 nM
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CP0014534
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(2S,3R,4E)-2-amino-3-hydroxyoctadec-4-en-1-yl dihydrogen phosphate
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C18H38NO5P
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3
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| 1 |
EC50 = 0.55 nM
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| 2 |
IC50 = 0.16 nM
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| 3 |
IC50 = 0.67 nM
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CP0876004
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(S)-1-((6-(3-(4-chlorophenyl)-2-methylpropoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
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C26H31Cl2NO3
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1
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| 1 |
EC50 = 0.55 nM
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CP0391146
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1-[[4-[5-[4-(2-methylpropyl)-5-phenyl-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C26H26N4O4
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1
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| 1 |
EC50 = 0.56 nM
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CP0873010
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rac-1-((1-methyl-6-(3-phenylbutoxy)-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
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C26H32ClNO3
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1
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| 1 |
EC50 = 0.6 nM
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CP0481056
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3-[[2-chloro-4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
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C26H30ClF3N2O3
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1
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| 1 |
EC50 = 0.6 nM
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CP0505506
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3-[[4-[(E)-N-[[4-cyclopentyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
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C25H29F3N2O3
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1
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| 1 |
EC50 = 0.6 nM
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CP0875990
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2-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)acetamide
Show/Hide
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C24H29NO3S
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1
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| 1 |
EC50 = 0.6 nM
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CP0403889
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N-[3-[2-ethyl-4-[3-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-3-oxopropyl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C29H41NO5S
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1
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| 1 |
EC50 = 0.6 nM
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CP0481261
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N-[3-[2,6-dimethyl-4-[5-[5-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C23H29N3O5S
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1
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| 1 |
EC50 = 0.6 nM
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CP0399288
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N-[(2S)-3-[4-[5-[2-(diethylamino)-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C26H35N5O5
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1
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| 1 |
EC50 = 0.6 nM
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CP0559242
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-5-[[methyl(propyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H36N4O5S
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1
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| 1 |
EC50 = 0.6 nM
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CP0508753
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N-[(2S)-3-[4-[5-(2-cyclopentyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 0.6 nM
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CP0534606
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N-[(2S)-3-[4-[5-(5-cyclopentyl-4-methoxypyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 0.6 nM
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CP0868470
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rac-1-((1-methyl-6-(2-methyl-3-phenylpropoxy)-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
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C26H32ClNO3
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1
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| 1 |
EC50 = 0.66 nM
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CP0403320
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3-(4-(5-(5-chloro-6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
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C20H20ClN3O4
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1
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| 1 |
EC50 = 0.7 nM
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CP0385152
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3-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-ethylphenyl]methylamino]propanoic acid
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C28H35F3N2O3
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1
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| 1 |
EC50 = 0.7 nM
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CP0869582
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(2RS)-3-(2,6-Dimethyl-4-(5-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)-1,3,4-oxadiazol-2-yl)phenoxy)propane-1,2-diol
Show/Hide
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C24H28N2O4S
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1
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| 1 |
EC50 = 0.7 nM
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CP0876518
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(S)-3-(2,6-Dimethyl-4-(3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)-1,2,4-oxadiazol-5-yl)phenoxy)-propane-1,2-diol
Show/Hide
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C24H28N2O4S
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1
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| 1 |
EC50 = 0.7 nM
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CP0390243
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-propylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C24H30N4O5
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1
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| 1 |
EC50 = 0.7 nM
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CP0440024
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[5-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C24H31N3O5S
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1
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| 1 |
EC50 = 0.7 nM
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CP0414582
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N-[(2S)-3-[4-[5-[5-[[butyl(methyl)amino]methyl]-4-methylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H38N4O5S
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1
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| 1 |
EC50 = 0.7 nM
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CP0469650
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N-[(2S)-3-[4-[5-(6-cyclopentyl-4-methoxypyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 0.7 nM
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CP0474138
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N-[(2S)-3-[4-[5-(6-cyclopentyloxy-5-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 0.7 nM
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CP0095972
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1-[[4-[5-[3-pyridin-2-yl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C22H16F3N5O4
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1
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| 1 |
EC50 = 0.71 nM
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CP0876631
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(1R,2S)-2-(4-(5-(3-cyano-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)cyclopropanecarboxylic acid
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C23H21N3O4
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1
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| 1 |
EC50 = 0.8 nM
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CP0419851
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1-(3-methyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
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C24H22F3NO3S
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2
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| 1 |
EC50 = 0.8 nM
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| 2 |
IC50 = 1.8 nM
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CP0876020
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3-(4-((S)-2,3-Dihydroxypropoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C25H32O4S
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1
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| 1 |
EC50 = 0.8 nM
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CP0390246
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N-[(2S)-3-[4-[5-(5-cyclopentyl-6-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O5
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1
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| 1 |
EC50 = 0.8 nM
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CP0542142
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1-[[4-[5-(4-propyl-5-pyridin-2-yl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H23N5O4
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1
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| 1 |
EC50 = 0.82 nM
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CP0915964
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1-((6-(3-(4-fluorophenyl)propoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
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C25H29ClFNO3
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1
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| 1 |
EC50 = 0.84 nM
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CP0430641
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(S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutyl dihydrogen phosphate
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C18H32NO5P
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1
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| 1 |
EC50 = 0.85 nM
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CP0873458
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(R)-1-((6-(3-(4-fluorophenyl)-2-methylpropoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
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C26H31ClFNO3
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1
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| 1 |
EC50 = 0.85 nM
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CP0408502
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3-(4-(5-(5-(1,1-difluoro-2-methylpropyl)pyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
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C21H21F2N3O3
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1
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| 1 |
EC50 = 0.9 nM
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CP0876019
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N-(3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)propyl)-2-hydroxyacetamide
Show/Hide
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C27H35NO4S
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1
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| 1 |
EC50 = 0.9 nM
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CP0379598
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N-[(2S)-3-[2-ethyl-4-[5-(3-ethyl-4,5,6,7-tetrahydro-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H33N3O5S
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1
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| 1 |
EC50 = 0.9 nM
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CP0434024
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N-[3-[2,6-dimethyl-4-[5-(5-propylthiophen-2-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C22H27N3O5S
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1
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| 1 |
EC50 = 0.9 nM
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CP0433972
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N-[(2S)-3-[4-[5-(4-cyclopentyl-6-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O5
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1
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| 1 |
EC50 = 0.9 nM
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CP0446794
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(5-methyl-6-pentan-3-ylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H36N4O5
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1
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| 1 |
EC50 = 0.9 nM
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CP0572693
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N-[(2S)-3-[4-[5-[5-[(dimethylamino)methyl]-4-methylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C24H32N4O5S
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1
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| 1 |
EC50 = 0.9 nM
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CP0391147
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1-[[4-[5-[5-phenyl-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C23H17F3N4O4
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1
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| 1 |
EC50 = 0.98 nM
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CP0420055
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1-[[4-[5-(4,5-diphenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C28H22N4O4
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1
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| 1 |
EC50 = 0.99 nM
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CP0880198
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(2RS)-3-(2,6-Dimethyl-4-(2-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)oxazol-5-yl)phenoxy)propane-1,2-diol
Show/Hide
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C25H29NO4S
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1
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| 1 |
EC50 = 1 nM
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CP0390240
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[5-methyl-6-(2-methylpropyl)pyridin-3-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H34N4O5
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1
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| 1 |
EC50 = 1 nM
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CP0446791
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N-[(2S)-3-[4-[5-(2-cyclohexyl-6-methylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H36N4O5
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1
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| 1 |
EC50 = 1 nM
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CP0402896
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1-[[4-[5-(4-propan-2-yl-5-pyridin-2-yl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
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C24H23N5O4
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1
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| 1 |
EC50 = 1 nM
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CP0414583
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N-[(2S)-3-[4-[5-[4-(diethylaminomethyl)-3-ethylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C29H40N4O5
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1
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| 1 |
EC50 = 1 nM
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CP0420267
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N-[(2S)-3-[2-ethyl-4-[5-[3-ethyl-4-[[ethyl(methyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H38N4O5
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1
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| 1 |
EC50 = 1 nM
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CP0508775
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N-[(2S)-3-[4-[5-(2-cyclopentyloxy-6-methylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 1 nM
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CP0534607
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N-[(2S)-3-[4-[5-(6-cyclopentyloxy-4-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 1 nM
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CP0887462
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((1R,3S)-1-amino-3-(2-(2-butoxyethoxy)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
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C23H33N2O6PS
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1
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| 1 |
EC50 = 1 nM
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CP0394080
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3-(4-(5-(4-isopropoxy-3-methoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
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C22H24N2O5
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1
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| 1 |
EC50 = 1.1 nM
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CP0873459
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(S)-1-((6-(2-(4-fluorobenzyl)butoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
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C27H33ClFNO3
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1
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| 1 |
EC50 = 1.1 nM
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CP0851940
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3-(3,5-Dichloro-4-(2-hydroxyethoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C22H24Cl2O3S
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1
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| 1 |
EC50 = 1.1 nM
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CP0875386
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2-((3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)propyl)amino)-acetic acid
Show/Hide
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C27H35NO4S
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1
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| 1 |
EC50 = 1.1 nM
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CP0895768
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(S)-3-(2,6-Dimethyl-4-(5-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]-thiophen-1-yl)-1,2,4-oxadiazol-3-yl)phenoxy)-propane-1,2-diol
Show/Hide
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C24H28N2O4S
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1
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| 1 |
EC50 = 1.1 nM
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CP0386357
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N-[(2S)-3-[2-ethyl-4-[5-(3-ethylspiro[6,7-dihydro-4H-2-benzothiophene-5,1'-cyclopropane]-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H35N3O5S
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1
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| 1 |
EC50 = 1.1 nM
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CP0403891
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3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3-ethylspiro[6,7-dihydro-4H-2-benzothiophene-5,1'-cyclopropane]-1-yl)propan-1-one
Show/Hide
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C26H34O4S
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1
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| 1 |
EC50 = 1.1 nM
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CP0414585
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-[[methyl(2-methylpropyl)amino]methyl]-5-propan-2-ylphenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C31H44N4O5
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1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0554783
|
N-[(2S)-3-[2-ethyl-4-[5-[3-ethyl-5-[[methyl(2-methylpropyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C30H42N4O5
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0401799
|
N-[(2S)-3-[4-[5-(2-cyclopentyloxy-6-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H36N4O6
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0420001
|
N-[(2S)-3-[4-[5-(2-cyclobutyloxy-6-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0474136
|
N-[(2S)-3-[2-ethyl-4-[5-(6-methoxy-4-pentan-3-ylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O6
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0529936
|
2-[(3R)-1-[(2S)-2-[4-[5-[5-cyclohexyl-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]-2-hydroxyethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C27H31F3N4O5
|
1
|
| 1 |
EC50 = 1.1 nM
|
|
|
|
CP0393039
|
N-[3-[2-ethyl-6-methyl-4-[3-oxo-3-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propyl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H39NO5S
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0393042
|
N-[3-[2,6-dimethyl-4-[3-oxo-3-[(2S,4R)-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-dien-7-yl]propyl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H35NO5S
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 1.3 nM
|
|
|
|
CP0403893
|
3-[[3-[2,6-dimethyl-4-[3-oxo-3-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propyl]phenoxy]-2-hydroxypropyl]amino]propanoic acid
Show/Hide
|
C28H39NO5S
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0469651
|
N-[(2S)-3-[2-ethyl-4-[5-(4-methoxy-6-pentan-3-ylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O6
|
1
|
| 1 |
EC50 = 1.2 nM
|
|
|
|
CP0135100
|
2-[(3R)-1-[(2S)-2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C27H25F3N4O5
|
2
|
| 1 |
EC50 = 1.2 nM
|
|
|
| 2 |
EC50 = 5 nM
|
|
|
|
CP0419848
|
1-(3-fluoro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19F4NO3S
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 2.7 nM
|
|
|
|
CP0425423
|
1-(3,5-dimethyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H24F3NO3S
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0395616
|
N-[3-[2,6-dimethyl-4-[5-[(2S,4R)-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-dien-7-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H31N3O5S
|
2
|
| 1 |
EC50 = 1.3 nM
|
|
|
| 2 |
EC50 = 1.4 nM
|
|
|
|
CP0379604
|
N-[(2S)-3-[4-[3-(5,5-dimethyl-3-propyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-3-oxopropyl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C30H43NO5S
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0404698
|
N-[3-[4-[3-[5,5-dimethyl-3-(trifluoromethyl)-6,7-dihydro-4H-2-benzothiophen-1-yl]-3-oxopropyl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H36F3NO5S
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0442590
|
N-[3-[2-ethyl-4-[3-(3-methoxy-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-3-oxopropyl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H39NO6S
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0466509
|
N-[(2S)-3-[4-[5-[6-(diethylamino)-4-methylpyridin-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H35N5O5
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0541599
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[6-methyl-4-(2-methylpropyl)pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0414584
|
N-[(2S)-3-[4-[5-[4-[(dimethylamino)methyl]-3-ethylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0420274
|
N-[(2S)-3-[2-ethyl-4-[5-[5-[[ethyl(methyl)amino]methyl]-4-methylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H34N4O5S
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0386156
|
1-[[4-[5-(5-phenyl-4-propan-2-yl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H24N4O4
|
1
|
| 1 |
EC50 = 1.3 nM
|
|
|
|
CP0405750
|
1-(3-ethyl-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H24F3NO3S
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 3.5 nM
|
|
|
|
CP0419853
|
1-(3-chloro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19ClF3NO3S
|
2
|
| 1 |
EC50 = 1.4 nM
|
|
|
| 2 |
IC50 = 3.2 nM
|
|
|
|
CP0507797
|
3-[[6-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]pyridin-3-yl]methylamino]propanoic acid
Show/Hide
|
C25H30F3N3O3
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0869520
|
3-(4-(2-Aminoethoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C24H31NO2S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0880199
|
3-(4-((R)-2,3-Dihydroxypropoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C25H32O4S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0393043
|
3-[2-[2-ethyl-4-[5-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]ethylamino]propanoic acid
Show/Hide
|
C28H37N3O4S
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0568660
|
N-[(2S)-3-[4-[5-(5-cyclopentyl-6-methoxypyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 1.4 nM
|
|
|
|
CP0875385
|
(2R/S)-2-((3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)-2-hydroxy-propyl)amino)acetic acid
Show/Hide
|
C27H35NO5S
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0379609
|
N-[3-[2,6-dimethyl-4-[5-[5-methyl-4-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H31N3O5S
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0390197
|
N-[3-[2,6-dimethyl-4-[5-[3-methyl-4-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H31N3O5S
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0392960
|
N-[3-[2-ethyl-6-methyl-4-[5-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H35N3O5S
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0380074
|
N-[(2S)-3-[2-ethyl-4-[5-[4-methoxy-6-(2-methylpropyl)pyridin-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O6
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0380075
|
N-[(2S)-3-[4-[5-(5-cyclopentyl-6-methoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 1.5 nM
|
|
|
|
CP0469845
|
6-(cyclohexyl(cyclopropylmethyl)amino)-N-(2-methyl-4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C22H29N5O3S
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0417590
|
1-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-methylphenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C28H33F3N2O3
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0379610
|
N-[3-[2,6-dimethyl-4-[5-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H33N3O5S
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0381995
|
3-[4-(2,3-dihydroxypropoxy)-3,5-dimethylphenyl]-1-(3-ethyl-5-methyl-4,5,6,7-tetrahydro-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C25H34O4S
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0407408
|
1-[[4-[5-(4-ethyl-5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C24H22N4O4
|
1
|
| 1 |
EC50 = 1.6 nM
|
|
|
|
CP0379607
|
N-[3-[4-[5-(5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H33N3O5S
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0409761
|
1-[[4-[5-(4-methyl-3-phenyl-1,2-oxazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
EC50 = 1.7 nM
|
|
|
|
CP0865103
|
3-(3-Chloro-4-(2-hydroxyethoxy)-5-methylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C23H27ClO3S
|
1
|
| 1 |
EC50 = 1.8 nM
|
|
|
|
CP0379602
|
N-[(2S)-3-[2-ethyl-4-[5-(3-methoxy-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H35N3O6S
|
1
|
| 1 |
EC50 = 1.8 nM
|
|
|
|
CP0445537
|
N-[(2S)-3-[4-[5-(2-butylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 1.8 nM
|
|
|
|
CP0390654
|
3-(4-(5-(3-fluoro-4-isopropoxyphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H21FN2O4
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0392956
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-methyl-6-pyrrolidin-1-ylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H33N5O5
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0549747
|
N-[(2R)-3-[2-ethyl-6-methyl-4-[5-[5-methyl-6-(2-methylpropyl)pyridin-3-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 1.9 nM
|
|
|
|
CP0415044
|
3-(1H-Indol-4-yl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0481055
|
3-[[4-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]-2-methylphenyl]methylamino]propanoic acid
Show/Hide
|
C27H33F3N2O3
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0876613
|
1-((2R/S)-3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)-2-hydroxy-propyl)azetidine-3-carboxylic acid
Show/Hide
|
C29H37NO5S
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0392958
|
N-[(2S)-3-[4-[5-(2-cyclohexyl-6-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H38N4O5
|
1
|
| 1 |
EC50 = 2 nM
|
|
|
|
CP0440035
|
N-[(2S)-3-[4-[5-[6-(diethylamino)-5-methylpyridin-3-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H35N5O5
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0442126
|
N-[(2S)-3-[2-ethyl-4-[5-(2-ethylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0434662
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-5-[[methyl(2-methylpropyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
|
| 1 |
EC50 = 2.1 nM
|
|
|
|
CP0478376
|
3-[[5-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]thiophen-2-yl]methylamino]propanoic acid
Show/Hide
|
C24H29F3N2O3S
|
1
|
| 1 |
EC50 = 2.2 nM
|
|
|
|
CP0529935
|
2-[(3R)-1-[(2S)-2-hydroxy-2-[4-[5-[5-(2-methylpropyl)-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C25H29F3N4O5
|
1
|
| 1 |
EC50 = 2.3 nM
|
|
|
|
CP0408158
|
5-(4-cyclohexylphenyl)-3-o-tolyl-1,2,4-oxadiazole
Show/Hide
|
C21H22N2O
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
|
CP0428538
|
1-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C24H22F3NO3S
|
2
|
| 1 |
EC50 = 2.4 nM
|
|
|
| 2 |
IC50 = 4.3 nM
|
|
|
|
CP0443215
|
(2S)-3-[2-ethyl-4-[5-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-methylpropan-1-ol
Show/Hide
|
C27H36N2O3S
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
|
CP0550702
|
2-[(3R)-1-[(2S)-2-hydroxy-2-[4-[5-[3-pyridin-2-yl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C26H24F3N5O5
|
1
|
| 1 |
EC50 = 2.4 nM
|
|
|
|
CP0487810
|
3-[[5-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]pyridin-2-yl]methylamino]propanoic acid
Show/Hide
|
C25H30F3N3O3
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0865102
|
3-(3,5-Dimethyl-4-(2-(methylamino)ethoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C25H33NO2S
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0865106
|
3-(4-(2-Hydroxyethoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C24H30O3S
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0415391
|
3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C25H34O4S
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0414586
|
N-[(2S)-3-[4-[5-[3-[[butyl(methyl)amino]methyl]-5-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
|
| 1 |
EC50 = 2.6 nM
|
|
|
|
CP0419847
|
1-(3,5-dichloro-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H18Cl2F3NO3S
|
2
|
| 1 |
EC50 = 2.7 nM
|
|
|
| 2 |
IC50 = 7.5 nM
|
|
|
|
CP0906431
|
1-((6-(3-(2-fluorophenyl)propoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C25H29ClFNO3
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0443773
|
N-[3-[4-[3-[3,5-dimethyl-4-(2-methylpropyl)thiophen-2-yl]-3-oxopropyl]-2,6-dimethylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H37NO5S
|
1
|
| 1 |
EC50 = 2.7 nM
|
|
|
|
CP0908208
|
1-(3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)propyl)azetidine-3-carboxylic acid
Show/Hide
|
C29H37NO4S
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0440021
|
N-[(2S)-3-[2-ethyl-4-[5-(5-ethyl-6-pyrrolidin-1-ylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H35N5O5
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0420270
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-[[methyl(2-methylpropyl)amino]methyl]-5-propylphenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C31H44N4O5
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0566502
|
N-[(2S)-3-[2-ethyl-4-[5-[5-[[2-hydroxyethyl(methyl)amino]methyl]-4-methylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H34N4O6S
|
1
|
| 1 |
EC50 = 2.8 nM
|
|
|
|
CP0429861
|
6-(cyclohexyl(propyl)amino)-N-(2-methyl-4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C21H29N5O3S
|
1
|
| 1 |
EC50 = 2.9 nM
|
|
|
|
CP0501185
|
1-[[1-methyl-6-(4-phenylbutoxy)-3,4-dihydronaphthalen-2-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H31NO3
|
1
|
| 1 |
EC50 = 2.9 nM
|
|
|
|
CP0469848
|
3-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)propanoic acid
Show/Hide
|
C25H33N5O5S
|
2
|
| 1 |
EC50 = 3 nM
|
|
|
| 2 |
Ki = 2 nM
|
|
|
|
CP0496093
|
1-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylbenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C27H35N5O3
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0856515
|
1-((1-methyl-6-(3-phenylpropoxy)-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C25H30ClNO3
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0884526
|
(E)-3-(2,5-Difluorophenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-1Hcyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)prop-2-en-1-one
Show/Hide
|
C19H18F2N2O
|
1
|
| 1 |
EC50 = 3 nM
|
|
|
|
CP0381847
|
3-(4-(5-(4-methoxy-3-(trifluoromethyl)phenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C20H17F3N2O4
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0420271
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-methyl-6-[[methyl(2-methylpropyl)amino]methyl]pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H39N5O5
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0401707
|
1-[[4-[5-(4-cyclopropyl-5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C25H22N4O4
|
1
|
| 1 |
EC50 = 3.2 nM
|
|
|
|
CP0419849
|
1-(3-bromo-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H19BrF3NO3S
|
2
|
| 1 |
EC50 = 3.3 nM
|
|
|
| 2 |
IC50 = 13 nM
|
|
|
|
CP0876016
|
N-(2-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)ethyl)methane-sulfonamide
Show/Hide
|
C25H33NO4S2
|
1
|
| 1 |
EC50 = 3.3 nM
|
|
|
|
CP0394070
|
3-(4-(5-(5-isobutylpyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0878803
|
2-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)-N-methyl-acetamide
Show/Hide
|
C25H31NO3S
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0442591
|
3-[4-[(2R)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C25H34O4S
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0542143
|
1-[[4-[5-(4-ethyl-5-pyridin-2-yl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H21N5O4
|
1
|
| 1 |
EC50 = 3.4 nM
|
|
|
|
CP0874453
|
(2R/S)-2-((3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)propyl)amino)-succinic acid
Show/Hide
|
C29H37NO6S
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0420266
|
N-[(2S)-3-[2-ethyl-4-[5-[3-ethyl-4-(pyrrolidin-1-ylmethyl)phenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H38N4O5
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0532768
|
(3S)-1-[(2S)-2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
|
C26H23F3N4O5
|
1
|
| 1 |
EC50 = 3.5 nM
|
|
|
|
CP0568786
|
N-[(2S)-3-[2-ethyl-4-[5-[3-[[ethyl(methyl)amino]methyl]-5-methylphenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
EC50 = 3.6 nM
|
|
|
|
CP0875395
|
3-(2-Methoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-1Hcyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)propan-1-one
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
EC50 = 3.8 nM
|
|
|
|
CP0440023
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(6-propan-2-ylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0421311
|
2-[(3R)-1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C29H32N4O5
|
2
|
| 1 |
EC50 = 3.9 nM
|
|
|
| 2 |
IC50 = 0.21 nM
|
|
|
|
CP0440083
|
2-[(3R)-1-[(2S)-2-hydroxy-2-[4-[5-[5-phenyl-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C27H25F3N4O5
|
1
|
| 1 |
EC50 = 3.9 nM
|
|
|
|
CP0854743
|
1-((6-(3-(3-fluorophenyl)propoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C25H29ClFNO3
|
1
|
| 1 |
EC50 = 4 nM
|
|
|
|
CP0474142
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-5-[[methyl(propyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H38N4O5
|
1
|
| 1 |
EC50 = 4.1 nM
|
|
|
|
CP0550700
|
2-[(3R)-1-[2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C27H25F3N4O5
|
2
|
| 1 |
EC50 = 4.2 nM
|
|
|
| 2 |
IC50 = 0.11 nM
|
|
|
|
CP0386358
|
N-[3-[4-[5-(5-ethylthiophen-2-yl)-1,2,4-oxadiazol-3-yl]-2,6-dimethylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C21H25N3O5S
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0395614
|
1-[3-[2,6-dimethyl-4-[3-oxo-3-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propyl]phenoxy]-2-hydroxypropyl]azetidine-3-carboxylic acid
Show/Hide
|
C29H39NO5S
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0469682
|
N-[(2S)-3-[4-[5-[2-[[butyl(methyl)amino]methyl]-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H39N5O5
|
1
|
| 1 |
EC50 = 4.3 nM
|
|
|
|
CP0874455
|
2-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)-N-(2-hydroxy-ethyl)acetamide
Show/Hide
|
C26H33NO4S
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0875387
|
3-(3-Ethyl-4-(2-hydroxyethoxy)-5-methylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C25H32O3S
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0386332
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[6-methyl-5-(2-methylpropyl)pyridin-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 4.4 nM
|
|
|
|
CP0873456
|
(R)-1-((6-(2-(4-fluorobenzyl)-3-methylbutoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C28H35ClFNO3
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0399285
|
N-[(2S)-3-[4-[5-(4-cyclopentyl-6-methoxypyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 4.5 nM
|
|
|
|
CP0865104
|
3-(4-(2-Hydroxyethoxy)-2-methoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C23H28O4S
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0435144
|
N-[(2S)-3-[2-ethyl-4-[5-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H37N3O5S
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0392893
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(6-propylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 4.6 nM
|
|
|
|
CP0876614
|
3-(4-(3-Hydroxypropoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C25H32O3S
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0379596
|
N-[(2S)-3-[2-ethyl-4-[5-(3-ethylspiro[6,7-dihydro-4H-2-benzothiophene-5,1'-cyclopentane]-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C30H39N3O5S
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0445563
|
N-[3-[4-[5-(5-butylthiophen-2-yl)-1,2,4-oxadiazol-3-yl]-2,6-dimethylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C23H29N3O5S
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0493876
|
3-[2-ethyl-4-[5-(3-ethyl-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]propanoic acid
Show/Hide
|
C26H32N2O4S
|
1
|
| 1 |
EC50 = 4.7 nM
|
|
|
|
CP0869584
|
(2R/S)-3-(4-(2-Hydroxy-3-((2-hydroxyethyl)amino)propoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)-propan-1-one
Show/Hide
|
C27H37NO4S
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0395617
|
N-[(2S)-3-[4-[3-(5,5-dimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-3-oxopropyl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H37NO5S
|
1
|
| 1 |
EC50 = 4.8 nM
|
|
|
|
CP0401708
|
1-[[4-[5-(4-methyl-5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H20N4O4
|
1
|
| 1 |
EC50 = 5 nM
|
|
|
|
CP0895803
|
3-(4-(2-((2-Hydroxyethyl)amino)ethoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C26H35NO3S
|
1
|
| 1 |
EC50 = 5.1 nM
|
|
|
|
CP0389626
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-(3-methylbutyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 5.1 nM
|
|
|
|
CP0542111
|
3-[2-ethyl-4-[5-[5-ethyl-6-[methyl(propan-2-yl)amino]pyridin-3-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenyl]-N-(2-hydroxyethyl)propanamide
Show/Hide
|
C27H37N5O3
|
1
|
| 1 |
EC50 = 5.1 nM
|
|
|
|
CP0420042
|
N-[(2S)-3-[4-[5-[4-[[butyl(methyl)amino]methyl]-3-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0420054
|
1-[[4-[5-(4-tert-butyl-5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C26H26N4O4
|
1
|
| 1 |
EC50 = 5.3 nM
|
|
|
|
CP0501220
|
N-[(2S)-3-[4-[5-[5-[(dimethylamino)methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C23H30N4O5S
|
1
|
| 1 |
EC50 = 5.4 nM
|
|
|
|
CP0541600
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[6-(2-methylpropyl)pyridin-3-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 5.7 nM
|
|
|
|
CP0878807
|
3-(4-(2-Hydroxyethoxy)-3-methylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C23H28O3S
|
1
|
| 1 |
EC50 = 5.8 nM
|
|
|
|
CP0443173
|
26-tert-butyl-13-(2,4,4-trimethylpentan-2-yl)-3,6,9,16,19,22-hexaoxatricyclo[22.3.1.0^{10,15}]octacosa-1(28),10(15),11,13,24,26-hexaene-28-carboxylic acid
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C24H19F6NO3S
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2
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| 1 |
EC50 = 5.9 nM
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| 2 |
IC50 = 7.7 nM
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CP0383844
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6-(cyclohexyl(cyclopropylmethyl)amino)-N-(6-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide
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C23H28N6O
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1
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| 1 |
EC50 = 6 nM
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CP0526346
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6-(cyclohexyl(cyclopropylmethyl)amino)-N-(2-methyl-4-(N-methylsulfamoyl)phenyl)pyrimidine-4-carboxamide
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C23H31N5O3S
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1
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| 1 |
EC50 = 6 nM
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CP0386360
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(3,5,5-triethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C30H41N3O5S
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1
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| 1 |
EC50 = 6 nM
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CP0395615
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3-[4-(2-aminoethoxy)-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
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C24H33NO2S
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1
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| 1 |
EC50 = 6.1 nM
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CP0853015
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3-(4-(3-Hydroxy-2-(hydroxymethyl)propoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
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C26H34O4S
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1
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| 1 |
EC50 = 6.3 nM
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CP0414532
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N-[(2S)-3-[4-[5-[5-[(dimethylamino)methyl]-3,4-dimethylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C25H34N4O5S
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1
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| 1 |
EC50 = 6.4 nM
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CP0899670
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3-(2-Chloro-4-(2-hydroxyethoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
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C22H25ClO3S
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1
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| 1 |
EC50 = 6.5 nM
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CP0851941
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3-(4-(3-Aminopropoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
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C25H33NO2S
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1
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| 1 |
EC50 = 6.6 nM
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CP0403890
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N-[3-[4-[5-[3-ethyl-5-methyl-4-(2-methylpropyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2,6-dimethylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C26H35N3O5S
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1
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| 1 |
EC50 = 6.6 nM
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CP0899669
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3-(3,5-Dimethyl-4-(3-(methylamino)propoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
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C26H35NO2S
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1
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| 1 |
EC50 = 6.8 nM
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CP0420265
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N-[(2S)-3-[2-ethyl-4-[5-[5-[[ethyl(methyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C24H32N4O5S
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1
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| 1 |
EC50 = 6.8 nM
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CP0469777
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(3S)-1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
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C28H30N4O5
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2
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| 1 |
EC50 = 6.9 nM
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| 2 |
IC50 = 1 nM
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CP0429919
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3-(Pyridin-4-yl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
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C18H19N3O
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1
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| 1 |
EC50 = 7 nM
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CP0447419
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6-(dipropylamino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
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C18H22N6O
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2
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| 1 |
EC50 = 7 nM
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| 2 |
Ki = 3 nM
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CP0387947
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3-[2-ethyl-6-methyl-4-[5-[(2S,4R)-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-dien-7-yl]-1,2,4-oxadiazol-3-yl]phenyl]propanoic acid
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C25H28N2O3S
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1
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| 1 |
EC50 = 7 nM
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CP0379608
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3-[4-(3-amino-2-hydroxypropoxy)-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
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C25H35NO3S
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1
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| 1 |
EC50 = 7 nM
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CP0403242
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[2-amino-4-[4-[4-(2-ethyl-1,3-oxazol-4-yl)phenyl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate;hydrochloride
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C22H28ClN2O6P
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1
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| 1 |
EC50 = 7 nM
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CP0469680
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N-[(2S)-3-[4-[5-[4-[(dimethylamino)methyl]-3-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C26H34N4O5
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1
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| 1 |
EC50 = 7.1 nM
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CP0499809
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N-[(2S)-3-[4-[5-(2-cyclohexyl-6-methoxypyridin-4-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C28H36N4O6
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1
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| 1 |
EC50 = 7.3 nM
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CP0508073
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[2-amino-2-(hydroxymethyl)-4-[4-[2-(4-methoxyphenyl)-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
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C21H25N2O7P
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1
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| 1 |
EC50 = 7.6 nM
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CP0379605
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N-[3-[2,6-dimethyl-4-[3-[5-(2-methylpropyl)thiophen-2-yl]-3-oxopropyl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C24H33NO5S
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1
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| 1 |
EC50 = 7.7 nM
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CP0527793
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1-[2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]azetidine-3-carboxylic acid
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C24H19F3N4O5
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2
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| 1 |
EC50 = 7.8 nM
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| 2 |
IC50 = 5.8 nM
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CP0551851
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(3S)-1-[2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
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C26H23F3N4O5
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2
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| 1 |
EC50 = 7.8 nM
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| 2 |
IC50 = 0.47 nM
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CP0552961
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(3S)-1-[(2S)-2-hydroxy-2-[4-[5-[5-(2-methylpropyl)-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
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C24H27F3N4O5
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1
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| 1 |
EC50 = 7.8 nM
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CP0559246
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N-[(2S)-3-[4-[5-[2-(diethylamino)-6-methylpyridin-4-yl]-1,3,4-oxadiazol-2-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
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C26H35N5O5
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1
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| 1 |
EC50 = 7.9 nM
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CP0511030
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3-[[4-[(E)-N-[[4-(2-fluorophenyl)-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
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C26H24F4N2O3
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1
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| 1 |
EC50 = 8 nM
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CP0554782
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N-[(2S)-3-[4-[5-[3-[(dimethylamino)methyl]-5-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H34N4O5
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1
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| 1 |
EC50 = 8 nM
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CP0541601
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N-[3-[2-ethyl-6-methyl-4-[5-[2-(3-methylbutyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H34N4O5
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1
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| 1 |
EC50 = 8.4 nM
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CP0444984
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-methyl-6-[[methyl(propyl)amino]methyl]pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H37N5O5
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1
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| 1 |
EC50 = 8.5 nM
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CP0390429
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6-(cyclohexyl(cyclopropylmethyl)amino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
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C22H26N6O
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1
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| 1 |
EC50 = 9 nM
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CP0574214
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3-[[4-[(E)-C-methyl-N-[[4-phenyl-3-(trifluoromethyl)phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
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C26H25F3N2O3
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1
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| 1 |
EC50 = 9 nM
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CP0372514
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(Z,Z)-5-[3-Chloro-4-((2R)-2,3-dihydroxy-propoxy)-benzylidene]-2-propylimino-3-o-tolyl-thiazolidin-4-one
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C23H25ClN2O4S
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1
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| 1 |
EC50 = 9.1 nM
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CP0473849
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[2-amino-4-[4-[2-(4-chlorophenyl)-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
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C20H22ClN2O6P
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1
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| 1 |
EC50 = 9.1 nM
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CP0539722
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N-[(2S)-3-[4-[5-[5-(diethylamino)-6-methylpyridin-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H35N5O5
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1
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| 1 |
EC50 = 9.5 nM
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CP0438157
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(Z,Z)-5-[3-Chloro-4-((2S)-2,3-dihydroxy-propoxy)-benzylidene]-2-propylimino-3-otolyl-thiazolidin-4-one
Show/Hide
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C23H25ClN2O4S
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1
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| 1 |
EC50 = 9.7 nM
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CP0537872
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(3S)-1-[(2S)-2-hydroxy-2-[4-[5-[5-phenyl-4-(trifluoromethyl)-1,2-oxazol-3-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
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C26H23F3N4O5
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1
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| 1 |
EC50 = 9.7 nM
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CP0876610
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3-(3-Chloro-4-(2-hydroxyethoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C22H25ClO3S
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1
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| 1 |
EC50 = 9.8 nM
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CP0472429
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-cyclohexyl-2-isopropyliminothiazolidin-4-one
Show/Hide
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C19H23ClN2O2S
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1
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| 1 |
EC50 = 10 nM
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CP0436615
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3-[[(E)-2-methyl-3-[4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
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C23H29NO3
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1
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| 1 |
EC50 = 10 nM
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CP0483485
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N-[(2S)-3-[4-[5-[4-(diethylaminomethyl)-3-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H38N4O5
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1
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| 1 |
EC50 = 10 nM
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CP0887483
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((1R,3S)-1-amino-3-(2-heptyl-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
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C24H35N2O4PS
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1
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| 1 |
EC50 = 10 nM
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CP0876017
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3-(4-(2-(Dimethylamino)ethoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C26H35NO2S
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1
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| 1 |
EC50 = 10.7 nM
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CP0396855
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[2-amino-2-(hydroxymethyl)-4-[4-[2-[4-(trifluoromethyl)phenyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
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C21H22F3N2O6P
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1
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| 1 |
EC50 = 10.9 nM
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CP0383616
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3-[3-Oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenyl]-benzenesulfonamide
Show/Hide
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C19H21N3O3S
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1
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| 1 |
EC50 = 11 nM
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CP0490773
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(Z,Z)-5-[3-Chloro-4-(2-hydroxy-ethoxy)-benzylidene]-2-propylimino-3-o-tolylthiazolidin-4-one
Show/Hide
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C22H23ClN2O3S
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1
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| 1 |
EC50 = 11 nM
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CP0501179
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3-[[1-methyl-6-(4-phenylbutoxy)-3,4-dihydronaphthalen-2-yl]methylamino]propanoic acid
Show/Hide
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C25H31NO3
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1
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| 1 |
EC50 = 11 nM
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CP0567014
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3-[[4-[(E)-N-[[4-(4-fluorophenyl)-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
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C26H24F4N2O3
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1
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| 1 |
EC50 = 11 nM
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CP0395619
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3-[4-[2-(2-hydroxyethylamino)ethoxy]-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
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C26H37NO3S
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1
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| 1 |
EC50 = 11 nM
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CP0511185
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N-[(2S)-3-[4-[5-(4-cyclopentyloxy-6-methylpyridin-2-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H34N4O6
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1
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| 1 |
EC50 = 11 nM
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CP0527794
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2-[1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
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C29H32N4O5
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1
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| 1 |
EC50 = 11 nM
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CP0421194
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6-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)hexanoic acid
Show/Hide
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C27H32N2O3
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1
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| 1 |
EC50 = 12 nM
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CP0447420
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2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)acetic acid
Show/Hide
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C24H31N5O5S
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1
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| 1 |
EC50 = 12 nM
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CP0526347
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6-((cyclopropylmethyl)(propyl)amino)-N-(6-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
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C20H24N6O
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1
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| 1 |
EC50 = 12 nM
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CP0915931
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rac-(Z,Z)-5-[3-Chloro-4-(2,3-dihydroxy-propoxy)-benzylidene]-2-propylimino-3-otolyl-thiazolidin-4-one
Show/Hide
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C23H25ClN2O4S
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1
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| 1 |
EC50 = 12 nM
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CP0902825
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((1R,3S)-1-amino-3-(2-(hexyloxy)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
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C23H33N2O5PS
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1
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| 1 |
EC50 = 12 nM
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CP0550701
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(3S)-1-[(2S)-2-hydroxy-2-[4-[5-[3-pyridin-2-yl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
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C25H22F3N5O5
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1
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| 1 |
EC50 = 12 nM
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CP0380863
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[2-amino-2-(hydroxymethyl)-4-[4-[2-(4-methylphenyl)-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
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C21H25N2O6P
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1
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| 1 |
EC50 = 12.8 nM
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CP0415286
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6-((cyclopropylmethyl)(propyl)amino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
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C19H22N6O
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1
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| 1 |
EC50 = 13 nM
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CP0483484
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-4-[[methyl(2-methylpropyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C29H40N4O5
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1
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| 1 |
EC50 = 13 nM
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CP0409138
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[2-amino-2-(hydroxymethyl)-4-[4-[4-(2-propyl-1,3-oxazol-4-yl)phenyl]phenyl]butyl] dihydrogen phosphate;hydrochloride
Show/Hide
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C23H30ClN2O6P
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1
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| 1 |
EC50 = 13.3 nM
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CP0893675
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3-(4-(3-((2-Hydroxyethyl)amino)propoxy)-3,5-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C27H37NO3S
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1
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| 1 |
EC50 = 13.4 nM
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CP0408513
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4-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)butanoic acid
Show/Hide
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C25H28N2O3
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1
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| 1 |
EC50 = 14 nM
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CP0434450
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3-[4-[2-hydroxy-3-(2-hydroxyethylamino)propoxy]-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
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C27H39NO4S
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1
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| 1 |
EC50 = 14 nM
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CP0854262
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2-amino-4-(4-(4-butylphenoxy)-2-chlorophenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
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C21H29ClNO6P
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1
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| 1 |
EC50 = 14 nM
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CP0407396
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-5-(methylaminomethyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C23H30N4O5S
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1
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| 1 |
EC50 = 14 nM
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CP0474123
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N-[(2S)-3-[4-[5-[3,4-dimethyl-5-[[methyl(propyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H38N4O5S
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1
|
| 1 |
EC50 = 14 nM
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CP0501218
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N-[(2S)-3-[2-ethyl-4-[5-[4-[[ethyl(methyl)amino]methyl]-3-methylphenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O5
|
1
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| 1 |
EC50 = 14 nM
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CP0511321
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3-[[4-[(E)-N-[[4-(furan-2-yl)-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C24H23F3N2O4
|
1
|
| 1 |
EC50 = 15 nM
|
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CP0876018
|
3-(4-(2-Hydroxyethoxy)phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]-thiophen-1-yl)propan-1-one
Show/Hide
|
C22H26O3S
|
1
|
| 1 |
EC50 = 15 nM
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CP0379838
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[2-amino-2-(hydroxymethyl)-4-[4-[1-[4-(trifluoromethoxy)phenyl]triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C20H22F3N4O6P
|
1
|
| 1 |
EC50 = 15 nM
|
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CP0420269
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-5-[(2-methylpropylamino)methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H38N4O5
|
1
|
| 1 |
EC50 = 15 nM
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|
|
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CP0394073
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3-(4-(5-(5-butylpyridin-2-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 = 16 nM
|
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CP0400052
|
3-(2-Chloro-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C19H19ClN2O
|
1
|
| 1 |
EC50 = 16 nM
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CP0540795
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3-[[4-[(E)-N-[[4-(3,4-difluorophenyl)-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H23F5N2O3
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
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CP0433921
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3-(Phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C19H20N2O
|
2
|
| 1 |
EC50 = 16 nM
|
|
|
| 2 |
EC50 = 34 nM
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CP0414338
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[2-amino-4-[4-[2-(4-fluorophenyl)-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C20H22FN2O6P
|
1
|
| 1 |
EC50 = 16.3 nM
|
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CP0400053
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3-(Pyridin-3-yl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
EC50 = 17 nM
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CP0463725
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3-[[5-[(E)-N-[[4-cyclohexyl-3-(trifluoromethyl)phenyl]methoxy]-C-methylcarbonimidoyl]furan-2-yl]methylamino]propanoic acid
Show/Hide
|
C24H29F3N2O4
|
1
|
| 1 |
EC50 = 17 nM
|
|
|
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CP0869583
|
3-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenyl)propanoic acid
Show/Hide
|
C25H30O3S
|
1
|
| 1 |
EC50 = 17.8 nM
|
|
|
|
CP0508745
|
[2-amino-4-[4-[2-[(4-chlorophenyl)methyl]-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C21H24ClN2O6P
|
1
|
| 1 |
EC50 = 17.8 nM
|
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|
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CP0410678
|
3-[[4-[(E)-C-methyl-N-[[4-thiophen-2-yl-3-(trifluoromethyl)phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C24H23F3N2O3S
|
1
|
| 1 |
EC50 = 18 nM
|
|
|
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CP0469849
|
3-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)benzylamino)propanoic acid
Show/Hide
|
C25H33N5O3
|
2
|
| 1 |
EC50 = 19 nM
|
|
|
| 2 |
Ki = 9 nM
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|
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CP0375772
|
(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentanoic acid
Show/Hide
|
C19H31NO3
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
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CP0472432
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-propylimino-3-o-tolyl-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
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CP0395618
|
3-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C24H32O3S
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
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CP0379846
|
[2-amino-2-(hydroxymethyl)-4-[4-[1-(4-propylphenyl)triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C22H29N4O5P
|
1
|
| 1 |
EC50 = 19 nM
|
|
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CP0902823
|
((1R,3S)-1-amino-3-(2-propyl-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
|
C20H27N2O4PS
|
1
|
| 1 |
EC50 = 19 nM
|
|
|
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CP0851080
|
2-amino-4-(4-(4-(2-cyclopropyloxazol-4-yl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C23H27N2O7P
|
1
|
| 1 |
EC50 = 19.8 nM
|
|
|
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CP0490135
|
4-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)butanoic acid
Show/Hide
|
C26H35N5O5S
|
2
|
| 1 |
EC50 = 20 nM
|
|
|
| 2 |
Ki = 8 nM
|
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|
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CP0390201
|
(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
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CP0854745
|
1-((1-methyl-6-(4-phenylbutan-2-yloxy)-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C26H32ClNO3
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
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CP0873457
|
1-((6-(2,2-dimethyl-3-phenylpropoxy)-1-methyl-3,4-dihydronaphthalen-2-yl)methyl)azetidine-3-carboxylic acid hydrochloride
Show/Hide
|
C27H34ClNO3
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
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CP0379603
|
N-[(2S)-3-[4-[5-(5,5-dimethyl-3-propyl-6,7-dihydro-4H-2-benzothiophen-1-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H39N3O5S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0379606
|
3-[4-[(2S)-2,3-dihydroxypropoxy]-3,5-dimethylphenyl]-1-(3-ethyl-4,5,6,7-tetrahydro-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C24H32O4S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0414581
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-5-[(2-methylpropylamino)methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H36N4O5S
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0945748
|
((1R,3S)-1-amino-3-(2-(butylthio)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
|
C21H29N2O4PS2
|
1
|
| 1 |
EC50 = 20 nM
|
|
|
|
CP0501458
|
3-[[(E)-3-[4-(3-phenylpropoxy)phenyl]but-2-enyl]amino]propanoic acid
Show/Hide
|
C22H27NO3
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0390199
|
3-(4-hydroxy-3,5-dimethylphenyl)-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C22H28O2S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0471597
|
3-[2,6-dimethyl-4-[3-oxo-3-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propyl]phenyl]propanoic acid
Show/Hide
|
C25H32O3S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0508754
|
N-[(2S)-3-[4-[5-(5-cyclopentyloxy-6-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H34N4O6
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0902822
|
((1R,3S)-1-amino-3-(2-pentyl-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
|
C22H31N2O4PS
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
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CP0414361
|
[2-amino-2-(hydroxymethyl)-4-[4-[1-[4-(trifluoromethyl)phenyl]triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C20H22F3N4O5P
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
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CP0168083
|
2-[(3R)-1-[(2R)-2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C27H25F3N4O5
|
1
|
| 1 |
EC50 = 22 nM
|
|
|
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CP0456032
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-(4-propan-2-ylphenyl)-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C23H29N2O6P
|
1
|
| 1 |
EC50 = 22.2 nM
|
|
|
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CP0404704
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(5-methyl-6-pyrrolidin-1-ylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H33N5O5
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
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CP0466512
|
N-[(2S)-3-[2-ethyl-4-[5-(6-ethylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
EC50 = 23 nM
|
|
|
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CP0901837
|
3-(4-(2-Hydroxyethoxy)-2,3,5-trimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C25H32O3S
|
1
|
| 1 |
EC50 = 23.7 nM
|
|
|
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CP0503489
|
3-[[(E)-3-[2-chloro-4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
|
C22H26ClNO3
|
1
|
| 1 |
EC50 = 24 nM
|
|
|
|
CP0402281
|
3-(3,4-Dimethoxy-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C21H24N2O3
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0390430
|
6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C22H28N4O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
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CP0490504
|
1-[[4-[5-(3-phenyl-1,2-oxazol-5-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C22H18N4O4
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
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CP0456028
|
[2-amino-4-[4-[2-(4-ethylphenyl)-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C22H27N2O6P
|
1
|
| 1 |
EC50 = 25.4 nM
|
|
|
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CP0480178
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-[(4-methoxyphenyl)methyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C22H27N2O7P
|
1
|
| 1 |
EC50 = 25.8 nM
|
|
|
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CP0406669
|
3-(3-Trifluoromethyl-phenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C20H19F3N2O
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0459614
|
N-[(2S)-3-[2-ethyl-4-[5-(5-formyl-4-methylthiophen-2-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C22H25N3O6S
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0854261
|
2-amino-4-(2-chloro-4-(4-(2-ethyloxazol-4-yl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C22H26ClN2O7P
|
1
|
| 1 |
EC50 = 27 nM
|
|
|
|
CP0426428
|
(1R,2S)-2-[[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]cyclopentane-1-carboxylic acid
Show/Hide
|
C28H30N4O5
|
2
|
| 1 |
EC50 = 27 nM
|
|
|
| 2 |
IC50 = 0.51 nM
|
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CP0474137
|
N-[(2S)-3-[2-ethyl-4-[5-(2-methoxy-6-phenylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H30N4O6
|
1
|
| 1 |
EC50 = 28 nM
|
|
|
|
CP0895771
|
3-(4-(2-Hydroxyethoxy)-3-methoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C23H28O4S
|
1
|
| 1 |
EC50 = 28.6 nM
|
|
|
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CP0545730
|
[2-amino-2-(hydroxymethyl)-4-[4-[1-(4-propan-2-ylphenyl)triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C22H29N4O5P
|
1
|
| 1 |
EC50 = 29 nM
|
|
|
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CP0880202
|
3-(2-Methoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-1Hcyclopropa[3,4]cyclopenta[1,2-b]pyrrol-1-yl)propan-1-one
Show/Hide
|
C21H25NO2
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0902824
|
((1R,3S)-1-amino-3-(2-butoxy-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
|
C21H29N2O5PS
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0226356
|
(3S)-1-[(2R)-2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-1,2-oxazol-5-yl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
|
C26H23F3N4O5
|
1
|
| 1 |
EC50 = 30 nM
|
|
|
|
CP0514181
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(3-chloro-2-methyl-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C20H18Cl2N2O2S
|
1
|
| 1 |
EC50 = 31 nM
|
|
|
|
CP0471516
|
3-(4-(6-((cyclopropylmethyl)(propyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)propanoic acid
Show/Hide
|
C22H29N5O5S
|
2
|
| 1 |
EC50 = 33 nM
|
|
|
| 2 |
Ki = 6 nM
|
|
|
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CP0492133
|
3-[[(E)-2-methyl-3-[4-(3-phenylpropoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
|
C22H27NO3
|
1
|
| 1 |
EC50 = 33 nM
|
|
|
|
CP0372294
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-o-tolyl-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 34 nM
|
|
|
|
CP0478536
|
2-[(3S)-1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-yl]acetic acid
Show/Hide
|
C29H32N4O5
|
2
|
| 1 |
EC50 = 34 nM
|
|
|
| 2 |
IC50 = 4 nM
|
|
|
|
CP0875985
|
(2RS)-3-(2,6-Dimethyl-4-(5-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)-1,3,4-thiadiazol-2-yl)phenoxy)propane-1,2-diol
Show/Hide
|
C24H28N2O3S2
|
1
|
| 1 |
EC50 = 34.2 nM
|
|
|
|
CP0518908
|
2-(4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)benzylamino)acetic acid
Show/Hide
|
C24H31N5O3
|
2
|
| 1 |
EC50 = 35 nM
|
|
|
| 2 |
Ki = 12 nM
|
|
|
|
CP0407073
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(3-chloro-phenyl)-2-isopropyliminothiazolidin-4-one
Show/Hide
|
C19H16Cl2N2O2S
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0869941
|
2-amino-4-(4-(4-(4-fluorobenzyl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C24H27FNO6P
|
1
|
| 1 |
EC50 = 35 nM
|
|
|
|
CP0469846
|
6-(dipropylamino)-N-(2-methyl-4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H25N5O3S
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0478314
|
3-[[(E)-3-[2-methyl-4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
|
C23H29NO3
|
1
|
| 1 |
EC50 = 36 nM
|
|
|
|
CP0372314
|
(Z,Z)-5-(4-Hydroxy-3-methyl-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0909868
|
2-amino-2-(hydroxymethyl)-4-(4-(4-propylphenethyl)phenyl)butyl dihydrogen phosphate
Show/Hide
|
C22H32NO5P
|
1
|
| 1 |
EC50 = 37 nM
|
|
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|
CP0851931
|
(2RS)-3-(2,6-Dimethyl-4-(2-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)thiazol-5-yl)phenoxy)propane-1,2-diol
Show/Hide
|
C25H29NO3S2
|
1
|
| 1 |
EC50 = 37.8 nM
|
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CP0469778
|
3-[[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]propanoic acid
Show/Hide
|
C25H26N4O5
|
2
|
| 1 |
EC50 = 38 nM
|
|
|
| 2 |
IC50 = 0.13 nM
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CP0506444
|
N-[4-(aminomethyl)phenyl]-6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidine-4-carboxamide
Show/Hide
|
C22H29N5O
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0474126
|
N-[(2S)-3-[4-[5-[2-[(dimethylamino)methyl]-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H33N5O5
|
1
|
| 1 |
EC50 = 40 nM
|
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|
|
CP0851014
|
2-amino-2-(hydroxymethyl)-4-(4-(4-(2-methyloxazol-4-yl)phenoxy)phenyl)butyl dihydrogen phosphate
Show/Hide
|
C21H25N2O7P
|
1
|
| 1 |
EC50 = 40.9 nM
|
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|
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CP0480177
|
[2-amino-4-[4-[1-(4-chlorophenyl)triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H22ClN4O5P
|
1
|
| 1 |
EC50 = 42 nM
|
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|
|
CP0542201
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-(4-propylphenyl)-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C23H29N2O6P
|
1
|
| 1 |
EC50 = 42.4 nM
|
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CP0480441
|
1-[(E)-3-[4-(3-phenylpropoxy)phenyl]prop-2-enyl]azetidine-3-carboxylic acid
Show/Hide
|
C22H25NO3
|
1
|
| 1 |
EC50 = 43 nM
|
|
|
|
CP0375771
|
(S)-2-amino-4-(4-(heptyloxy)phenyl)-2-methylbutanoic acid
Show/Hide
|
C18H29NO3
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
|
CP0380263
|
1-[[4-[5-(5-phenyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C22H18N4O4
|
1
|
| 1 |
EC50 = 44 nM
|
|
|
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CP0501361
|
3-(4-(4-(3-phenylpropoxy)phenyl)-5,6-dihydropyridin-1(2H)-yl)propanoic acid
Show/Hide
|
C23H27NO3
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
|
CP0469683
|
N-[(2S)-3-[4-[5-[2-(diethylaminomethyl)-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H37N5O5
|
1
|
| 1 |
EC50 = 45 nM
|
|
|
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CP0419850
|
1-(3-methoxy-4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H22F3NO4S
|
2
|
| 1 |
EC50 = 47 nM
|
|
|
| 2 |
IC50 = 33 nM
|
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CP0454283
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H17ClN2O2S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0504085
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(3-chloro-4-methyl-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C20H18Cl2N2O2S
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
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CP0393041
|
3-[4-[3-(2-hydroxyethylamino)propoxy]-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C27H39NO3S
|
1
|
| 1 |
EC50 = 48 nM
|
|
|
|
CP0854263
|
2-amino-4-(4-(4-(2-ethyl-1H-imidazol-4-yl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C22H28N3O6P
|
1
|
| 1 |
EC50 = 48.1 nM
|
|
|
|
CP0554584
|
[2-amino-2-(hydroxymethyl)-4-[4-(2-thiophen-2-yl-1,3-oxazol-4-yl)phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C18H21N2O6PS
|
1
|
| 1 |
EC50 = 48.9 nM
|
|
|
|
CP0420273
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-4-(pyrrolidin-1-ylmethyl)phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H36N4O5
|
1
|
| 1 |
EC50 = 50 nM
|
|
|
|
CP0848817
|
4-(4-([1,1'-biphenyl]-4-yloxy)phenyl)-2-amino-2-(hydroxymethyl)butyldihydrogen phosphate
Show/Hide
|
C23H26NO6P
|
1
|
| 1 |
EC50 = 51 nM
|
|
|
|
CP0906687
|
2-amino-4-(4-(4-butylphenoxy)-2-fluorophenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H29FNO6P
|
1
|
| 1 |
EC50 = 52.9 nM
|
|
|
|
CP0550854
|
[2-amino-4-[4-[1-(4-ethylphenyl)triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C21H27N4O5P
|
1
|
| 1 |
EC50 = 53 nM
|
|
|
|
CP0504086
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2-chloro-phenyl)-2-isopropyliminothiazolidin-4-one
Show/Hide
|
C19H16Cl2N2O2S
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0541598
|
N-[(2S)-3-[4-[5-[4-(diethylamino)-6-methylpyridin-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H35N5O5
|
1
|
| 1 |
EC50 = 54 nM
|
|
|
|
CP0397029
|
[2-amino-4-[4-[2-[(4-fluorophenyl)methyl]-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C21H24FN2O6P
|
1
|
| 1 |
EC50 = 54.5 nM
|
|
|
|
CP0454270
|
(Z,Z)-3-Allyl-5-(3-chloro-4-hydroxy-benzylidene)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C16H17ClN2O2S
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0407397
|
N-[(2S)-3-[4-[5-[3,4-dimethyl-5-[[methyl(2-methylpropyl)amino]methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H40N4O5S
|
1
|
| 1 |
EC50 = 55 nM
|
|
|
|
CP0511453
|
3-[[6-(4-phenylbutoxy)-3,4-dihydronaphthalen-2-yl]methylamino]propanoic acid
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
EC50 = 57 nM
|
|
|
|
CP0388697
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-isopropyl-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C16H19ClN2O2S
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0495815
|
(Z,Z)-5-[4-(3-Hydroxy-propoxy)-benzylidene]-2-isopropylimino-3-phenylthiazolidin-4-one
Show/Hide
|
C22H24N2O3S
|
1
|
| 1 |
EC50 = 58 nM
|
|
|
|
CP0481271
|
3-[[4-[(E)-N-[(3-fluoro-4-phenylphenyl)methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C25H25FN2O3
|
1
|
| 1 |
EC50 = 61 nM
|
|
|
|
CP0440082
|
1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]pyrrolidine-3-carboxylic acid
Show/Hide
|
C27H28N4O5
|
2
|
| 1 |
EC50 = 61 nM
|
|
|
| 2 |
IC50 = 0.69 nM
|
|
|
|
CP0372306
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-(dimethyl-hydrazono)-3-phenylthiazolidin-4-one
Show/Hide
|
C18H16ClN3O2S
|
1
|
| 1 |
EC50 = 62 nM
|
|
|
|
CP0440075
|
2-amino-1-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethanol
Show/Hide
|
C22H22N4O3
|
2
|
| 1 |
EC50 = 64 nM
|
|
|
| 2 |
IC50 = 1.5 nM
|
|
|
|
CP0379843
|
[2-amino-2-(hydroxymethyl)-4-[4-(2-pentyl-1,3-oxazol-4-yl)phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C19H29N2O6P
|
1
|
| 1 |
EC50 = 64.1 nM
|
|
|
|
CP0429860
|
6-(cyclohexyl(methyl)amino)-N-(2-methyl-4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C19H25N5O3S
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0869940
|
2-amino-4-(4-(4-butylphenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H30NO6P
|
1
|
| 1 |
EC50 = 66.3 nM
|
|
|
|
CP0898296
|
2-amino-4-(4-(4-butylphenoxy)-3-fluorophenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H29FNO6P
|
1
|
| 1 |
EC50 = 66.3 nM
|
|
|
|
CP0372157
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-phenyl-2-propylimino-thiazolidin-4-one
Show/Hide
|
C19H17ClN2O2S
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0420268
|
N-[(2S)-3-[4-[5-[4-[(dimethylamino)methyl]-3,5-dimethylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H36N4O5
|
1
|
| 1 |
EC50 = 69 nM
|
|
|
|
CP0380879
|
[2-amino-4-[4-[2-(furan-2-yl)-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C18H21N2O7P
|
1
|
| 1 |
EC50 = 69.5 nM
|
|
|
|
CP0422247
|
(E/Z)-3-(3-(4-(3-phenylpropoxy)phenyl)allylamino)propanoic acid
Show/Hide
|
C21H25NO3
|
1
|
| 1 |
EC50 = 70 nM
|
|
|
|
CP0403894
|
3-[4-(3-hydroxypropoxy)-3,5-dimethylphenyl]-1-(3,5,5-trimethyl-6,7-dihydro-4H-2-benzothiophen-1-yl)propan-1-one
Show/Hide
|
C25H34O3S
|
1
|
| 1 |
EC50 = 71 nM
|
|
|
|
CP0374220
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2,3-dimethyl-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C21H21ClN2O2S
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0898303
|
2-amino-4-(4-(4-butylphenethyl)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C23H34NO5P
|
1
|
| 1 |
EC50 = 72 nM
|
|
|
|
CP0504558
|
N-(4-carbamoylphenyl)-6-[cyclohexyl(cyclopropylmethyl)amino]pyrimidine-4-carboxamide
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
|
CP0508074
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-[4-(trifluoromethoxy)phenyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C21H22F3N2O7P
|
1
|
| 1 |
EC50 = 74 nM
|
|
|
|
CP0407075
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-p-tolyl-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 78 nM
|
|
|
|
CP0403888
|
3-[4-(2,3-dihydroxypropoxy)-3,5-dimethylphenyl]-1-[(5S)-3-ethyl-5-hydroxy-5-methyl-6,7-dihydro-4H-2-benzothiophen-1-yl]propan-1-one
Show/Hide
|
C25H34O5S
|
1
|
| 1 |
EC50 = 79 nM
|
|
|
|
CP0851078
|
2-amino-4-(4-(4-benzylphenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C24H28NO6P
|
1
|
| 1 |
EC50 = 85.8 nM
|
|
|
|
CP0417785
|
3-Phenyl-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propan-1-one
Show/Hide
|
C19H22N2O
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0445538
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(2-methylpyridin-4-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C22H26N4O5
|
1
|
| 1 |
EC50 = 86 nM
|
|
|
|
CP0421165
|
3-(4-(5-(6-isobutylpyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
|
C21H23N3O3
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0457393
|
N-[(2R)-3-[2-ethyl-6-methyl-4-[5-[6-(2-methylpropyl)pyridin-3-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
EC50 = 89 nM
|
|
|
|
CP0898301
|
2-amino-4-(4-(4-(2-ethyloxazol-4-yl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C22H27N2O7P
|
1
|
| 1 |
EC50 = 89 nM
|
|
|
|
CP0851079
|
2-amino-4-(4-(4-ethylphenethyl)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H30NO5P
|
1
|
| 1 |
EC50 = 91.5 nM
|
|
|
|
CP0556777
|
[2-amino-2-(hydroxymethyl)-4-[4-(1-pentyltriazol-4-yl)phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C18H29N4O5P
|
1
|
| 1 |
EC50 = 93.9 nM
|
|
|
|
CP0373572
|
2-((4-(6-(cyclohexyl(cyclopropylmethyl)amino)pyrimidine-4-carboxamido)benzyl)(methyl)amino)acetic acid
Show/Hide
|
C25H33N5O3
|
2
|
| 1 |
EC50 = 94 nM
|
|
|
| 2 |
Ki = 29 nM
|
|
|
|
CP0505495
|
3-[[4-[(E)-C-methyl-N-[[4-(4-methylphenyl)-3-(trifluoromethyl)phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C27H27F3N2O3
|
1
|
| 1 |
EC50 = 94 nM
|
|
|
|
CP0495813
|
(Z,Z)-5-[4-(2-Hydroxy-ethoxy)-benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C21H22N2O3S
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0414527
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-methyl-6-(pyrrolidin-1-ylmethyl)pyridin-4-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C27H35N5O5
|
1
|
| 1 |
EC50 = 95 nM
|
|
|
|
CP0550712
|
4-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperazine-2-carboxylic acid
Show/Hide
|
C27H29N5O5
|
2
|
| 1 |
EC50 = 95 nM
|
|
|
| 2 |
IC50 = 9.4 nM
|
|
|
|
CP0851942
|
(3bS,4aR)-3,4,4-Trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole-1-carboxylic acid [2-(2-methoxy-phenyl)-methyl]-amide
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0483482
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-3-[[methyl(2-methylpropyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
|
| 1 |
EC50 = 97 nM
|
|
|
|
CP0372309
|
(Z,Z)-5-[4-(3-Hydroxy-propyl)-benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C22H24N2O2S
|
1
|
| 1 |
EC50 = 98 nM
|
|
|
|
CP0490776
|
(5Z)-2-butan-2-ylimino-5-[(3-chloro-4-hydroxyphenyl)methylidene]-3-phenyl-1,3-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0495817
|
(Z,Z)-5-[4-(2-Hydroxy-ethyl)-benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C21H22N2O2S
|
1
|
| 1 |
EC50 = 102 nM
|
|
|
|
CP0372305
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-cyclopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H15ClN2O2S
|
1
|
| 1 |
EC50 = 103 nM
|
|
|
|
CP0429862
|
6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-((dimethylamino)methyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C24H33N5O
|
2
|
| 1 |
EC50 = 104 nM
|
|
|
| 2 |
Ki = 51 nM
|
|
|
|
CP0407072
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-(2-methoxy-phenyl)-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O3S
|
1
|
| 1 |
EC50 = 106 nM
|
|
|
|
CP0542202
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-[(4-methylphenyl)methyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C22H27N2O6P
|
1
|
| 1 |
EC50 = 108.2 nM
|
|
|
|
CP0390202
|
(S)-3-amino-5-(4-(heptyloxy)phenyl)-3-methylpentane-1-sulfonic acid
Show/Hide
|
C19H33NO4S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0372130
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-m-tolyl-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 110 nM
|
|
|
|
CP0474140
|
(2S)-3-[4-[5-[2-(diethylaminomethyl)-6-methylpyridin-4-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]propane-1,2-diol
Show/Hide
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C25H34N4O4
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1
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| 1 |
EC50 = 110 nM
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CP0550711
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2-[1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-2-yl]acetic acid
Show/Hide
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C29H32N4O5
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2
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| 1 |
EC50 = 110 nM
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| 2 |
IC50 = 7 nM
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CP0397028
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[2-amino-2-(hydroxymethyl)-4-[4-[1-(4-methylphenyl)triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
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C20H25N4O5P
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1
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| 1 |
EC50 = 111 nM
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CP0374261
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(Z,Z)-2-Butylimino-5-(3-chloro-4-hydroxy-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H19ClN2O2S
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1
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| 1 |
EC50 = 112 nM
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CP0906686
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2-amino-4-(4-(3-(benzyloxy)phenylthio)-2-chlorophenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
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C24H27ClNO6PS
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1
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| 1 |
EC50 = 117 nM
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CP0402154
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4-[3-Oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenyl]-benzenesulfonamide
Show/Hide
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C19H21N3O3S
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1
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| 1 |
EC50 = 119 nM
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CP0436614
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3-[[(E)-3-[4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
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C22H27NO3
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1
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| 1 |
EC50 = 120 nM
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CP0410680
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3-[[4-[(E)-N-[(2-fluoro-4-phenylphenyl)methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
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C25H25FN2O3
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1
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| 1 |
EC50 = 120 nM
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CP0454281
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(Z,Z)-5-(4-Hydroxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C19H18N2O2S
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1
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| 1 |
EC50 = 122 nM
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CP0407074
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2-ethyl-phenyl)-2-isopropyliminothiazolidin-4-one
Show/Hide
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C21H21ClN2O2S
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1
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| 1 |
EC50 = 124 nM
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CP0882549
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3-(6-(2-chloro-6-ethylbenzylthio)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
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C24H29Cl2NO3S
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1
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| 1 |
EC50 = 125.89 nM
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CP0456030
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[2-amino-2-(hydroxymethyl)-4-[4-[1-(4-methoxyphenyl)triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
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C20H25N4O6P
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1
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| 1 |
EC50 = 126 nM
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CP0551849
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1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidin-3-ol
Show/Hide
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C27H30N4O4
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2
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| 1 |
EC50 = 128 nM
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| 2 |
IC50 = 13 nM
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CP0906718
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((1R,3S)-1-amino-3-(2-(butylamino)-4,5-dihydronaphtho[2,1-d]thiazol-7-yl)cyclopentyl)methyl dihydrogen phosphate
Show/Hide
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C21H30N3O4PS
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1
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| 1 |
EC50 = 130 nM
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CP0411203
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(5Z)-5-[[4-(2,3-dihydroxypropoxy)phenyl]methylidene]-3-phenyl-2-propan-2-ylimino-1,3-thiazolidin-4-one
Show/Hide
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C22H24N2O4S
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1
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| 1 |
EC50 = 143 nM
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CP0495814
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(Z,Z)-2-tert-Butylimino-5-(3-chloro-4-hydroxy-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H19ClN2O2S
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1
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| 1 |
EC50 = 147 nM
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CP0380878
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[2-amino-4-[4-[2-(4-cyanophenyl)-1,3-oxazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
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C21H22N3O6P
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1
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| 1 |
EC50 = 147.6 nM
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CP0372312
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(Z,Z)-5-(4-Dimethylamino-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C21H23N3OS
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1
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| 1 |
EC50 = 148 nM
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CP0501178
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3-[[(E)-3-[4-(5-phenylpentoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
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C23H29NO3
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1
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| 1 |
EC50 = 150 nM
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CP0411204
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2,6-dimethyl-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
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C21H21ClN2O2S
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1
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| 1 |
EC50 = 154 nM
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CP0456029
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[2-amino-2-(hydroxymethyl)-4-[4-[2-[(4-propan-2-ylphenyl)methyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
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C24H31N2O6P
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1
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| 1 |
EC50 = 154 nM
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CP0554785
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N-[(2S)-3-[4-[5-[5-[[2-(dimethylamino)ethyl-methylamino]methyl]-4-methylthiophen-2-yl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H39N5O5S
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1
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| 1 |
EC50 = 155 nM
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CP0882274
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2-amino-4-(4-(4-(4-ethylbenzyl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
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C26H32NO6P
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1
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| 1 |
EC50 = 157 nM
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CP0291779
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1-(4-(5-benzylbenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
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C26H22FNO3
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1
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| 1 |
EC50 = 160 nM
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CP0393732
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1-(4-(5-cyclohexylbenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
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C25H26FNO3
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1
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| 1 |
EC50 = 160 nM
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CP0377161
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3-(3-(4-(5-phenylpentyloxy)phenyl)propylamino)propanoic acid
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C23H31NO3
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1
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| 1 |
EC50 = 160 nM
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CP0414531
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N-[(2S)-3-[4-[5-[4-[(dimethylamino)methyl]phenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C25H32N4O5
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1
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| 1 |
EC50 = 160 nM
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CP0469795
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(3R)-1-[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]piperidine-3-carboxylic acid
Show/Hide
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C28H30N4O5
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2
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| 1 |
EC50 = 170 nM
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| 2 |
IC50 = 25 nM
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CP0848818
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2-amino-2-(hydroxymethyl)-4-(4-(4-(4-methylbenzyl)phenoxy)phenyl)butyl dihydrogen phosphate
Show/Hide
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C25H30NO6P
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1
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| 1 |
EC50 = 172 nM
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CP0490775
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2,4-dimethyl-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
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C21H21ClN2O2S
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1
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| 1 |
EC50 = 179 nM
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CP0372311
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(Z,Z)-2-Isopropylimino-5-(3-methoxy-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H20N2O2S
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1
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| 1 |
EC50 = 185 nM
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CP0372159
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-ethylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C18H15ClN2O2S
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1
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| 1 |
EC50 = 186 nM
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CP0501219
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[5-(methylaminomethyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C22H28N4O5S
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1
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| 1 |
EC50 = 189 nM
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CP0420272
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-(methylaminomethyl)phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C24H30N4O5
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1
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| 1 |
EC50 = 190 nM
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CP0501847
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6-(cyclohexyl(cyclopropylmethyl)amino)-N-(4-(methylsulfonyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
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C22H28N4O3S
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1
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| 1 |
EC50 = 193 nM
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CP0374219
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(Z,Z)-5-(4-Hydroxy-3-methoxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H20N2O3S
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1
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| 1 |
EC50 = 200 nM
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CP0454284
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(2Z,5Z)-2-(2,2-dimethylhydrazono)-5-(4-hydroxy-3-methoxybenzylidene)-3-phenylthiazolidin-4-one
Show/Hide
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C19H19N3O3S
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1
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| 1 |
EC50 = 200 nM
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CP0495820
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(Z,Z)-2-Isopropylimino-5-(4-methoxy-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H20N2O2S
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1
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| 1 |
EC50 = 201 nM
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CP0372155
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-cyclobutylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C20H17ClN2O2S
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1
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| 1 |
EC50 = 202 nM
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CP0899061
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2-amino-4-(4-(3-(4-ethylphenyl)propyl)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
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C22H32NO5P
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1
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| 1 |
EC50 = 203 nM
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CP0420275
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[5-[(propan-2-ylamino)methyl]thiophen-2-yl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C24H32N4O5S
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1
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| 1 |
EC50 = 203 nM
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CP0394068
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3-(4-(5-(6-isopropoxypyridin-3-yl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)propanoic acid
Show/Hide
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C20H21N3O4
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1
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| 1 |
EC50 = 208 nM
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CP0469847
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2-(4-(6-((cyclopropylmethyl)(propyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)acetic acid
Show/Hide
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C21H27N5O5S
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1
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| 1 |
EC50 = 208 nM
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CP0514018
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3-[[4-[(E)-N-[[4-(4-fluorophenyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
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C25H25FN2O3
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1
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| 1 |
EC50 = 210 nM
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CP0523993
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6-(cyclohexyl(methyl)amino)-N-(6-methyl-1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
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C20H24N6O
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1
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| 1 |
EC50 = 211 nM
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CP0495819
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(Z,Z)-5-(3,4-Dimethoxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C21H22N2O3S
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1
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| 1 |
EC50 = 224 nM
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CP0373469
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(Z,Z)-5-(3-Fluoro-4-hydroxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
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C19H17FN2O2S
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1
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| 1 |
EC50 = 225 nM
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CP0475006
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3-[[(E)-3-[2-methoxy-4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
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C23H29NO4
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1
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| 1 |
EC50 = 230 nM
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CP0407395
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N-[(2S)-3-[4-[5-[4-[(dimethylamino)methyl]-2-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C26H34N4O5
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1
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| 1 |
EC50 = 230 nM
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CP0414529
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-[(2-methylpropylamino)methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H36N4O5
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1
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| 1 |
EC50 = 230 nM
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CP0527792
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2-[1-[(2S)-2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]pyrrolidin-2-yl]acetic acid
Show/Hide
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C28H30N4O5
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2
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| 1 |
EC50 = 230 nM
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| 2 |
IC50 = 36 nM
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CP0875389
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3-(4-(2-Hydroxyethoxy)-3,5-dimethoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
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C24H30O5S
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1
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| 1 |
EC50 = 232 nM
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CP0447421
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4-(4-(6-((cyclopropylmethyl)(propyl)amino)pyrimidine-4-carboxamido)-3-methylphenylsulfonamido)butanoic acid
Show/Hide
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C23H31N5O5S
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1
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| 1 |
EC50 = 238 nM
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CP0381221
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(S)-4-amino-6-(4-(heptyloxy)phenyl)-4-methylhexanoic acid
Show/Hide
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C20H33NO3
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1
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| 1 |
EC50 = 240 nM
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CP0440018
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-(6-methylpyridin-3-yl)-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C22H26N4O5
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1
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| 1 |
EC50 = 248 nM
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CP0373470
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-(4-methoxy-phenyl)-thiazolidin-4-one
Show/Hide
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C20H19ClN2O3S
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1
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| 1 |
EC50 = 251 nM
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CP0882546
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2-(6-(2,6-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)ethyl dihydrogen phosphate hydrochloride
Show/Hide
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C21H25Cl3NO6P
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1
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| 1 |
EC50 = 251.19 nM
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CP0851077
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2-amino-4-(4-(4-(4-chlorobenzyl)phenoxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
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C24H27ClNO6P
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1
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| 1 |
EC50 = 254 nM
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CP0419837
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[2-amino-4-[4-[1-(4-cyanophenyl)triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
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C20H22N5O5P
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1
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| 1 |
EC50 = 257 nM
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CP0472428
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-(3-methoxy-phenyl)-thiazolidin-4-one
Show/Hide
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C20H19ClN2O3S
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1
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| 1 |
EC50 = 259 nM
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CP0483477
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-methyl-4-[(2-methylpropylamino)methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H38N4O5
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1
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| 1 |
EC50 = 270 nM
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CP0497166
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3-(Biphenyl-4-yl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
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C25H24N2O
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1
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| 1 |
EC50 = 280 nM
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CP0494106
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3-[[(E)-3-[3-methyl-4-(4-phenylbutoxy)phenyl]prop-2-enyl]amino]propanoic acid
Show/Hide
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C23H29NO3
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1
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| 1 |
EC50 = 280 nM
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CP0372316
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(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-hexyl-2-isopropylimino-thiazolidin-4-one
Show/Hide
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C19H25ClN2O2S
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1
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| 1 |
EC50 = 282 nM
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CP0875390
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(3bS,4aR)-N-(4-(2-Hydroxyethoxy)-2-methoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
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C22H27NO4S
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1
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| 1 |
EC50 = 282 nM
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CP0542112
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N-[(2S)-3-[2-ethyl-4-[5-[3-[[ethyl(methyl)amino]methyl]-4-methylphenyl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C27H36N4O5
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1
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| 1 |
EC50 = 285 nM
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CP0414580
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N-[(2S)-3-[2-ethyl-4-[5-[5-(ethylaminomethyl)thiophen-2-yl]-1,2,4-oxadiazol-3-yl]-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C23H30N4O5S
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1
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| 1 |
EC50 = 293 nM
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CP0507792
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3-[[4-[(E)-C-methyl-N-[(4-phenylphenyl)methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C25H26N2O3
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1
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| 1 |
EC50 = 300 nM
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CP0878806
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2-(2,6-Dimethyl-4-(3-oxo-3-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propyl)phenoxy)acetic acid
Show/Hide
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C24H28O4S
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1
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| 1 |
EC50 = 300 nM
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CP0474129
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-3-[[methyl(propyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
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C28H38N4O5
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1
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| 1 |
EC50 = 305 nM
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CP0559244
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N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[3-(propylaminomethyl)phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
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1
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| 1 |
EC50 = 305 nM
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CP0509642
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N-[(2S)-3-[4-[5-[3-[[butyl(methyl)amino]methyl]-4-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
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| 1 |
EC50 = 310 nM
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CP0410304
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3-[6-[(2-chloro-6-ethylphenyl)methoxy]spiro[2H-1-benzofuran-3,4'-piperidine]-1'-yl]-2-methylpropanoic acid;hydrochloride
Show/Hide
|
C25H31Cl2NO4
|
1
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| 1 |
EC50 = 316.23 nM
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CP0882547
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3-(6-(2,6-dichloro-4-methylbenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H26Cl3NO4
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0952523
|
3-(6-(2-chloro-6-(trifluoromethyl)benzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H24Cl2F3NO4
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0909867
|
2-amino-2-(hydroxymethyl)-4-(4-((3'-methoxy-[1,1'-biphenyl]-4-yl)oxy)phenyl)butyl dihydrogen phosphate
Show/Hide
|
C24H28NO7P
|
1
|
| 1 |
EC50 = 329 nM
|
|
|
|
CP0909865
|
2-amino-2-(hydroxymethyl)-4-(4-(4-(4-isopropylphenyl)butyl)phenyl)butyl dihydrogen phosphate
Show/Hide
|
C24H36NO5P
|
1
|
| 1 |
EC50 = 341 nM
|
|
|
|
CP0372307
|
(Z,Z)-5-[4-(3-Dimethylamino-propoxy)-benzylidene]-2-isopropylimino-3-phenylthiazolidin-4-one
Show/Hide
|
C24H29N3O2S
|
1
|
| 1 |
EC50 = 343 nM
|
|
|
|
CP0463484
|
[2-amino-2-(hydroxymethyl)-4-[4-[2-[[4-(trifluoromethyl)phenyl]methyl]-1,3-oxazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C22H24F3N2O6P
|
1
|
| 1 |
EC50 = 343 nM
|
|
|
|
CP0372153
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-cyclopentylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C21H19ClN2O2S
|
1
|
| 1 |
EC50 = 347 nM
|
|
|
|
CP0380308
|
1-(4-(5-butylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO3
|
1
|
| 1 |
EC50 = 350 nM
|
|
|
|
CP0372129
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-pyridin-3-ylthiazolidin-4-one
Show/Hide
|
C18H16ClN3O2S
|
1
|
| 1 |
EC50 = 356 nM
|
|
|
|
CP0430361
|
6-(dipropylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C17H22N4O2
|
1
|
| 1 |
EC50 = 375 nM
|
|
|
|
CP0398773
|
1-(4-(5-isobutylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO3
|
1
|
| 1 |
EC50 = 380 nM
|
|
|
|
CP0501868
|
6-(cyclohexylamino)-N-(4-hydroxy-2-(trifluoromethyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H19F3N4O2
|
1
|
| 1 |
EC50 = 382 nM
|
|
|
|
CP0554784
|
N-[(2S)-3-[4-[5-[3-[(dimethylamino)methyl]-4-methylphenyl]-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C26H34N4O5
|
1
|
| 1 |
EC50 = 385 nM
|
|
|
|
CP0373789
|
N-(2-chloro-4-hydroxyphenyl)-6-(cyclohexylamino)pyrimidine-4-carboxamide
Show/Hide
|
C17H19ClN4O2
|
2
|
| 1 |
EC50 = 390 nM
|
|
|
| 2 |
Ki = 380 nM
|
|
|
|
CP0539341
|
6-(cyclohexyl(ethyl)amino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
EC50 = 405 nM
|
|
|
|
CP0401704
|
(Z,Z)-5-(4-Hydroxymethyl-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 = 408 nM
|
|
|
|
CP0504719
|
6-(cyclohexyl(methyl)amino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
|
C19H22N6O
|
1
|
| 1 |
EC50 = 418 nM
|
|
|
|
CP0425181
|
1-(4-(5-butoxybenzofuran-2-yl)-3-methoxybenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H27NO5
|
1
|
| 1 |
EC50 = 420 nM
|
|
|
|
CP0400300
|
6-(cyclohexylamino)-N-(2-methyl-4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H23N5O3S
|
1
|
| 1 |
EC50 = 440 nM
|
|
|
|
CP0490134
|
6-(cyclohexylamino)-N-(2-fluoro-4-hydroxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C17H19FN4O2
|
2
|
| 1 |
EC50 = 440 nM
|
|
|
| 2 |
Ki = 340 nM
|
|
|
|
CP0393726
|
1-(4-(5-benzylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C26H23NO3
|
1
|
| 1 |
EC50 = 440 nM
|
|
|
|
CP0373472
|
(Z,Z)-5-(3-Hydroxy-4-methoxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C20H20N2O3S
|
1
|
| 1 |
EC50 = 444 nM
|
|
|
|
CP0869522
|
(3bS,4aR)-N-(2,4-Dimethoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 = 450 nM
|
|
|
|
CP0447433
|
5-[(S)-3-Amino-5-(4-heptyloxy-phenyl)-3-methyl-pentyl]-1,1-dioxo-1lambda*6*-[1,2,5]thiadiazolidin-3-one
Show/Hide
|
C21H35N3O4S
|
1
|
| 1 |
EC50 = 460 nM
|
|
|
|
CP0381566
|
4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylbenzoic acid
Show/Hide
|
C22H22N2O3
|
1
|
| 1 |
EC50 = 467 nM
|
|
|
|
CP0514180
|
(Z,Z)-3-[5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-4-oxo-thiazolidin-3-yl]-propionicacidethylester
Show/Hide
|
C18H21ClN2O4S
|
1
|
| 1 |
EC50 = 479 nM
|
|
|
|
CP0483483
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[2-methyl-5-[[methyl(2-methylpropyl)amino]methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C29H40N4O5
|
1
|
| 1 |
EC50 = 490 nM
|
|
|
|
CP0522161
|
1-(4-(5-phenoxybenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H21NO4
|
1
|
| 1 |
EC50 = 510 nM
|
|
|
|
CP0380312
|
1-(4-(5-butoxybenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO4
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0470769
|
1-(4-(5-butoxybenzofuran-2-yl)-3-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H24FNO4
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0880200
|
(3bS,4aR)-N-(2-Methoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C20H23NO2S
|
1
|
| 1 |
EC50 = 520 nM
|
|
|
|
CP0848807
|
2-amino-4-(4-((4'-ethyl-[1,1'-biphenyl]-4-yl)oxy)phenyl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C25H30NO6P
|
1
|
| 1 |
EC50 = 529 nM
|
|
|
|
CP0396852
|
[2-amino-2-(hydroxymethyl)-4-[4-[1-[[4-(trifluoromethyl)phenyl]methyl]triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C21H24F3N4O5P
|
1
|
| 1 |
EC50 = 551 nM
|
|
|
|
CP0398775
|
1-(4-(5-phenethylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C27H25NO3
|
1
|
| 1 |
EC50 = 580 nM
|
|
|
|
CP0372145
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-cyclohexylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C22H21ClN2O2S
|
1
|
| 1 |
EC50 = 584 nM
|
|
|
|
CP0380309
|
1-(4-(5-cyclohexylbenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C25H27NO3
|
1
|
| 1 |
EC50 = 600 nM
|
|
|
|
CP0393734
|
1-(4-(5-benzylbenzofuran-2-yl)-2-fluorobenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C26H22FNO3
|
1
|
| 1 |
EC50 = 620 nM
|
|
|
|
CP0454269
|
(Z,Z)-3-Benzyl-5-(3-chloro-4-hydroxy-benzylidene)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C20H19ClN2O2S
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0380883
|
[2-amino-4-[4-[1-[(4-chlorophenyl)methyl]triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C20H24ClN4O5P
|
1
|
| 1 |
EC50 = 630 nM
|
|
|
|
CP0869939
|
2-amino-2-(hydroxymethyl)-4-(4'-(2-propyloxazol-4-yl)-[1,1'-biphenyl]-4-yl)butyl dihydrogen phosphate
Show/Hide
|
C23H29N2O6P
|
1
|
| 1 |
EC50 = 632 nM
|
|
|
|
CP0480181
|
[2-amino-4-[4-[1-[(4-fluorophenyl)methyl]triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C20H24FN4O5P
|
1
|
| 1 |
EC50 = 638 nM
|
|
|
|
CP0540796
|
3-[[4-[(E)-C-methyl-N-[[4-(4-methylphenyl)phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H28N2O3
|
1
|
| 1 |
EC50 = 640 nM
|
|
|
|
CP0469843
|
6-(cyclohexyl(methyl)amino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
EC50 = 655 nM
|
|
|
|
CP0542205
|
[2-amino-4-[4-[1-[(4-ethylphenyl)methyl]triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C22H29N4O5P
|
1
|
| 1 |
EC50 = 685 nM
|
|
|
|
CP0511070
|
6-(cyclohexyl(methyl)amino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H22N4O2
|
2
|
| 1 |
EC50 = 700 nM
|
|
|
| 2 |
Ki = 810 nM
|
|
|
|
CP0380311
|
1-((6-(5-cyclohexylbenzofuran-2-yl)pyridin-3-yl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
EC50 = 720 nM
|
|
|
|
CP0374262
|
(Z,Z)-5-(3-Hydroxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H18N2O2S
|
1
|
| 1 |
EC50 = 752 nM
|
|
|
|
CP0869942
|
2-amino-4-(2-hexylchroman-6-yl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C20H34NO6P
|
1
|
| 1 |
EC50 = 800 nM
|
|
|
|
CP0390655
|
2-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)-3-methylphenyl)acetic acid
Show/Hide
|
C23H24N2O3
|
1
|
| 1 |
EC50 = 830 nM
|
|
|
|
CP0442592
|
3-[4-(2,3-dihydroxypropoxy)-3,5-dimethylphenyl]-1-[(5S)-3-ethyl-5-hydroxy-4,5,6,7-tetrahydro-2-benzothiophen-1-yl]propan-1-one
Show/Hide
|
C24H32O5S
|
1
|
| 1 |
EC50 = 860 nM
|
|
|
|
CP0454282
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-3-(2,4-dimethoxy-phenyl)-2-isopropylimino-thiazolidin-4-one
Show/Hide
|
C21H21ClN2O4S
|
1
|
| 1 |
EC50 = 875 nM
|
|
|
|
CP0851048
|
2-amino-2-(hydroxymethyl)-4-(4'-(2-methyloxazol-4-yl)-[1,1'-biphenyl]-4-yl)butyl dihydrogen phosphate
Show/Hide
|
C21H25N2O6P
|
1
|
| 1 |
EC50 = 876 nM
|
|
|
|
CP0909864
|
2-amino-4-(6-hexylnaphthalen-2-yl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H32NO5P
|
1
|
| 1 |
EC50 = 886 nM
|
|
|
|
CP0878804
|
3-(4-(2-Hydroxyethoxy)-2,6-dimethylphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C24H30O3S
|
1
|
| 1 |
EC50 = 902 nM
|
|
|
|
CP0372150
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-phenethylthiazolidin-4-one
Show/Hide
|
C21H21ClN2O2S
|
1
|
| 1 |
EC50 = 925 nM
|
|
|
|
CP0503563
|
3-[[(Z)-3-[4-(3-phenylpropoxy)phenyl]but-2-enyl]amino]propanoic acid
Show/Hide
|
C22H27NO3
|
1
|
| 1 |
EC50 = 930 nM
|
|
|
|
CP0909869
|
2-amino-4-(6-hexylnaphthalen-1-yl)-2-(hydroxymethyl)butyl dihydrogen phosphate
Show/Hide
|
C21H32NO5P
|
1
|
| 1 |
EC50 = 932 nM
|
|
|
|
CP0373791
|
6-(cyclohexylamino)-N-(4-(methylsulfonamido)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H23N5O3S
|
2
|
| 1 |
EC50 = 960 nM
|
|
|
| 2 |
Ki = 280 nM
|
|
|
|
CP0390203
|
(S)-1-(4-(heptyloxy)phenyl)-3-methyl-5-(1H-tetrazol-5-yl)pentan-3-amine
Show/Hide
|
C20H33N5O
|
1
|
| 1 |
EC50 = 960 nM
|
|
|
|
CP0511069
|
6-(cycloheptylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
EC50 = 973 nM
|
|
|
|
CP0374264
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-methylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C17H13ClN2O2S
|
1
|
| 1 |
EC50 = 990 nM
|
|
|
|
CP0863955
|
3-(6-(2,6-dichlorobenzyloxy)-7-fluoro-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H23Cl3FNO4
|
1
|
| 1 |
EC50 = 1000 nM
|
|
|
|
CP0514580
|
(Z,Z)-5-(4-Bromo-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H17BrN2OS
|
1
|
| 1 |
EC50 = 1038 nM
|
|
|
|
CP0433971
|
N-[(2S)-3-[2-ethyl-6-methyl-4-(5-pyridin-4-yl-1,2,4-oxadiazol-3-yl)phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C21H24N4O5
|
1
|
| 1 |
EC50 = 1110 nM
|
|
|
|
CP0373788
|
6-(Cyclohexylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H22N4O2
|
2
|
| 1 |
EC50 = 1160 nM
|
|
|
| 2 |
Ki = 550 nM
|
|
|
|
CP0374263
|
(Z,Z)-5-Benzylidene-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H18N2OS
|
1
|
| 1 |
EC50 = 1237 nM
|
|
|
|
CP0863961
|
3-(6-(2,6-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)-2-methylpropanoic acid hydrochloride
Show/Hide
|
C23H26Cl3NO4
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0960909
|
3-(6-(2-chloro-6-isopropylbenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C25H31Cl2NO4
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0480179
|
[2-amino-2-(hydroxymethyl)-4-[4-[1-[(4-methylphenyl)methyl]triazol-4-yl]phenyl]butyl] dihydrogen phosphate
Show/Hide
|
C21H27N4O5P
|
1
|
| 1 |
EC50 = 1287 nM
|
|
|
|
CP0455131
|
1-[[5-methyl-2-(4-phenylbutoxy)-8,9-dihydro-7H-benzo[7]annulen-6-yl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C27H33NO3
|
1
|
| 1 |
EC50 = 1300 nM
|
|
|
|
CP0543602
|
3-[[4-[(E)-N-[[4-(2-methoxyphenyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
EC50 = 1400 nM
|
|
|
|
CP0372308
|
(Z,Z)-5-[3-(2-Hydroxy-ethoxy)-benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C21H22N2O3S
|
1
|
| 1 |
EC50 = 1414 nM
|
|
|
|
CP0380310
|
1-(4-(5-(piperidin-1-yl)benzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0487579
|
3-[(3E)-3-[[4-(3-phenylpropoxy)phenyl]methylidene]piperidin-1-yl]propanoic acid
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0494650
|
3-(3-(4-(4-phenylbutoxy)phenyl)propylamino)propanoic acid
Show/Hide
|
C22H29NO3
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0567015
|
3-[[4-[(E)-N-[[4-(4-methoxyphenyl)phenyl]methoxy]-C-methylcarbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H28N2O4
|
1
|
| 1 |
EC50 = 1500 nM
|
|
|
|
CP0444011
|
2-amino-2-[2-[4-[4-[2-(2-hydroxypropyl)-1,3-oxazol-4-yl]phenyl]phenyl]ethyl]propane-1,3-diol;hydrochloride
Show/Hide
|
C23H29ClN2O4
|
1
|
| 1 |
EC50 = 1524 nM
|
|
|
|
CP0444335
|
US10179791, Compound 258
Show/Hide
|
C26H33NO4
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0863957
|
3-(6-(2,3-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl3NO4
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0477216
|
1-((5-(5-butoxybenzofuran-2-yl)thiophen-2-yl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C21H23NO4S
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0447149
|
3-(4-(4-(3-phenylpropoxy)phenyl)piperidin-1-yl)propanoic acid
Show/Hide
|
C23H29NO3
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0403887
|
3-[4-(2,3-dihydroxypropoxy)-3,5-dimethylphenyl]-1-[(5S)-5-(dimethylamino)-3-ethyl-4,5,6,7-tetrahydro-2-benzothiophen-1-yl]propan-1-one
Show/Hide
|
C26H37NO4S
|
1
|
| 1 |
EC50 = 1600 nM
|
|
|
|
CP0444012
|
2-amino-2-[2-[4-[4-(2-propyl-1,3-oxazol-4-yl)phenyl]phenyl]ethyl]propane-1,3-diol;hydrochloride
Show/Hide
|
C23H29ClN2O3
|
1
|
| 1 |
EC50 = 1611 nM
|
|
|
|
CP0414334
|
[2-amino-4-[4-[1-(4-fluorophenyl)triazol-4-yl]phenyl]-2-(hydroxymethyl)butyl] dihydrogen phosphate
Show/Hide
|
C19H22FN4O5P
|
1
|
| 1 |
EC50 = 1626 nM
|
|
|
|
CP0511322
|
3-[[4-[(E)-C-methyl-N-[[4-[2-(trifluoromethyl)phenyl]phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H25F3N2O3
|
1
|
| 1 |
EC50 = 1700 nM
|
|
|
|
CP0373573
|
6-(cyclohexylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C17H20N4O2
|
2
|
| 1 |
EC50 = 1780 nM
|
|
|
| 2 |
Ki = 1680 nM
|
|
|
|
CP0875391
|
(3bS,4aR)-N-(4-(2-Hydroxyethoxy)benzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 = 1800 nM
|
|
|
|
CP0522088
|
(Z,Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-3-(4-phenyl-butyl)-thiazolidin-4-one
Show/Hide
|
C23H25ClN2O2S
|
1
|
| 1 |
EC50 = 1815 nM
|
|
|
|
CP0520361
|
6-(cyclohexylamino)-N-(4-sulfamoylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C17H21N5O3S
|
1
|
| 1 |
EC50 = 1990 nM
|
|
|
|
CP0863962
|
3-(6-(2-chloro-6-propylbenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C25H31Cl2NO4
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0477215
|
1-(4-(6-butoxybenzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C23H25NO4
|
1
|
| 1 |
EC50 = 2000 nM
|
|
|
|
CP0459612
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-(methylaminomethyl)phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
EC50 = 2090 nM
|
|
|
|
CP0401998
|
N-(4-hydroxyphenyl)-6-(2-methylanilino)pyrimidine-4-carboxamide
Show/Hide
|
C18H16N4O2
|
2
|
| 1 |
EC50 = 2100 nM
|
|
|
| 2 |
Ki = 840 nM
|
|
|
|
CP0542113
|
N-[(2S)-3-[2-ethyl-6-methyl-4-[5-[4-methyl-3-[(2-methylpropylamino)methyl]phenyl]-1,2,4-oxadiazol-3-yl]phenoxy]-2-hydroxypropyl]-2-hydroxyacetamide
Show/Hide
|
C28H38N4O5
|
1
|
| 1 |
EC50 = 2350 nM
|
|
|
|
CP0436609
|
1-[(E)-3-[4-(3-phenylpropoxy)phenyl]prop-2-enyl]piperidine-4-carboxylic acid
Show/Hide
|
C24H29NO3
|
1
|
| 1 |
EC50 = 2400 nM
|
|
|
|
CP0478097
|
3-(3-(4-(3-phenylpropoxy)phenyl)propylamino)propanoic acid
Show/Hide
|
C21H27NO3
|
1
|
| 1 |
EC50 = 2600 nM
|
|
|
|
CP0447150
|
3-(3-(4-(6-phenylhexyloxy)phenyl)propylamino)propanoic acid
Show/Hide
|
C24H33NO3
|
1
|
| 1 |
EC50 = 2700 nM
|
|
|
|
CP0518906
|
6-(cyclohexylamino)-N-(1H-indazol-5-yl)pyrimidine-4-carboxamide
Show/Hide
|
C18H20N6O
|
2
|
| 1 |
EC50 = 2710 nM
|
|
|
| 2 |
Ki = 458 nM
|
|
|
|
CP0878805
|
3-(4-(2-Hydroxyethoxy)-2,6-dimethoxyphenyl)-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophen-1-yl)propan-1-one
Show/Hide
|
C24H30O5S
|
1
|
| 1 |
EC50 = 3110 nM
|
|
|
|
CP0393727
|
1-((2-(5-butoxybenzofuran-2-yl)thiazol-5-yl)methyl)azetidine-3-carboxylic acid
Show/Hide
|
C20H22N2O4S
|
1
|
| 1 |
EC50 = 3200 nM
|
|
|
|
CP0950442
|
3-(6-(2-chloro-6-(trifluoromethoxy)benzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H24Cl2F3NO5
|
1
|
| 1 |
EC50 = 3981.07 nM
|
|
|
|
CP0559385
|
US10179791, Compound 128
Show/Hide
|
C23H25Cl2NO4
|
1
|
| 1 |
EC50 = 5011.87 nM
|
|
|
|
CP0862081
|
3-(6-(3-phenylpropoxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C24H30ClNO4
|
1
|
| 1 |
EC50 = 5011.87 nM
|
|
|
|
CP0863964
|
3-(6-(2,6-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl3NO4
|
1
|
| 1 |
EC50 = 6309.57 nM
|
|
|
|
CP0930972
|
2-(6-(2,6-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)acetic acid hydrochloride
Show/Hide
|
C21H22Cl3NO4
|
1
|
| 1 |
EC50 = 6309.57 nM
|
|
|
|
CP0948587
|
3-(6-(2-chloro-6-fluorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl2FNO4
|
1
|
| 1 |
EC50 = 6309.57 nM
|
|
|
|
CP0372148
|
(Z,Z)-2-Isopropylimino-5-(2-methyl-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
|
C20H20N2OS
|
1
|
| 1 |
EC50 = 6452 nM
|
|
|
|
CP0865105
|
(3bS,4aR)-N-(2,5-Dimethoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 = 7280 nM
|
|
|
|
CP0506445
|
N-(2H-benzotriazol-5-yl)-6-[cyclohexyl(methyl)amino]pyrimidine-4-carboxamide
Show/Hide
|
C18H21N7O
|
1
|
| 1 |
EC50 = 7300 nM
|
|
|
|
CP0895696
|
(3bS,4aR)-N-(2,3-Dimethoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 = 7490 nM
|
|
|
|
CP0880201
|
(4aR,5aS)-N-(2-Methoxybenzyl)-1,5,5-trimethyl-4,4a,5,5a-tetrahydro-1Hcyclopropa[4,5]cyclopenta[1,2-c]pyrazole-3-carboxamide
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
EC50 = 8570 nM
|
|
|
|
CP0407071
|
(Z,Z)-5-[4-(2-Hydroxy-1-hydroxymethyl-ethoxy)-benzylidene]-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C22H24N2O4S
|
1
|
| 1 |
EC50 = 8631 nM
|
|
|
|
CP0374042
|
(3bS,4aR)-3,4,4-Trimethyl-1-[(3-phenyl)-allyl]-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole
Show/Hide
|
C19H22N2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0402153
|
1-((3bS,4aR)-3,4,4-Trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-heptan-1-one
Show/Hide
|
C17H26N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0402280
|
(3bS,4aR)-3,4,4-Trimethyl-1-[(2-phenyl)-ethenesulfonyl]-3b,4,4a,5-tetrahydro-1H-cyclopropa[3,4]cyclopenta[1,2-c]pyrazole
Show/Hide
|
C18H20N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0490936
|
3-Cyclohexyl-1-((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]pyrazol-1-yl)-propenone
Show/Hide
|
C19H26N2O
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372152
|
(Z,Z)-3-[5-(3-Chloro-4-hydroxy-benzylidene)-2-isopropylimino-4-oxo-thiazolidin-3-yl]-propionicacid
Show/Hide
|
C16H17ClN2O4S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0372310
|
(Z,Z)-5-(2-Chloro-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H17ClN2OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0407077
|
(Z,Z)-2-Isopropylimino-5-(2-methoxy-benzylidene)-3-phenyl-thiazolidin-4-one
Show/Hide
|
C20H20N2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0454271
|
(Z)-5-(3-Chloro-4-hydroxy-benzylidene)-2-imino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C16H11ClN2O2S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0495818
|
(Z,Z)-5-(3,4-Dihydroxy-benzylidene)-2-isopropylimino-3-phenyl-thiazolidin-4-one
Show/Hide
|
C19H18N2O3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0389617
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]-methylamino]-4-(dimethylamino)butanoic acid
Show/Hide
|
C30H36ClN3O5S
|
3
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 3.4 nM
|
|
|
| 3 |
Kd = 0.67 nM
|
|
|
|
CP0507818
|
3-[[4-[(E)-C-methyl-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H25F3N2O3
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0540791
|
3-[[4-[(E)-C-methyl-N-[[4-phenyl-2-(trifluoromethyl)phenyl]methoxy]carbonimidoyl]phenyl]methylamino]propanoic acid
Show/Hide
|
C26H25F3N2O3
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0853014
|
(3bS,4aR)-N-(2-(2-Hydroxyethoxy)benzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0869521
|
(3bS,4aR)-N-(3-(2-Hydroxyethoxy)benzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]-thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0876021
|
2-(3-Methoxy-4-(((3bS,4aR)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-cyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamido)methyl)phenoxy)acetic acid
Show/Hide
|
C22H25NO5S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0876612
|
(3bS,4aR)-N-(2,6-Dimethoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydrocyclopropa[3,4]cyclopenta[1,2-c]thiophene-1-carboxamide
Show/Hide
|
C21H25NO3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0899671
|
(3bS,4aR)-N-(2-Methoxybenzyl)-3,4,4-trimethyl-3b,4,4a,5-tetrahydro-2Hcyclopropa[3,4]cyclopenta[1,2-c]pyrrole-1-carboxamide
Show/Hide
|
C20H24N2O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0096517
|
2-amino-2-[2-[4-[4-(2-ethyl-1,3-oxazol-4-yl)phenyl]phenyl]ethyl]propane-1,3-diol;hydrochloride
Show/Hide
|
C22H27ClN2O3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0429299
|
2-amino-2-[2-[4-[4-[2-(1-hydroxyethyl)-1,3-oxazol-4-yl]phenyl]phenyl]ethyl]propane-1,3-diol;hydrochloride
Show/Hide
|
C22H27ClN2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0084726
|
2-(4-octylphenethyl)-2-aminopropane-1,3-diol
Show/Hide
|
C19H33NO2
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
IC50 = 840 nM
|
|
|
|
CP0863958
|
3-(6-(2,6-dichlorobenzylthio)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl3NO3S
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0882551
|
3-(6-(3-chlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H25Cl2NO4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0539342
|
6-(cyclohexylamino)-N-(1H-indol-5-yl)pyrimidine-4-carboxamide
Show/Hide
|
C19H21N5O
|
1
|
| 1 |
EC50 = 12100 nM
|
|
|
|
CP0863963
|
3-(6-(2,5-dichlorobenzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl3NO4
|
1
|
| 1 |
EC50 = 12589.25 nM
|
|
|
|
CP0400299
|
6-(cyclopentylamino)-N-(4-hydroxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C16H18N4O2
|
2
|
| 1 |
EC50 = 16700 nM
|
|
|
| 2 |
Ki = 2130 nM
|
|
|
|
CP0469842
|
6-(tert-butylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C16H20N4O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0469844
|
N-(4-acetamidophenyl)-6-(cyclohexylamino)pyrimidine-4-carboxamide
Show/Hide
|
C19H23N5O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0471515
|
6-(cyclohexylamino)-N-(2,4-difluorophenyl)pyrimidine-4-carboxamide
Show/Hide
|
C17H18F2N4O
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0485611
|
6-(cyclohexylamino)-N-(4-(2-hydroxyethyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C19H24N4O2
|
2
|
| 1 |
EC50 > 20000 nM
|
|
|
| 2 |
Ki = 2000 nM
|
|
|
|
CP0511068
|
6-(cyclopropylamino)-N-(4-hydroxy-2-methylphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C15H16N4O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0511071
|
6-(cyclohexylamino)-N-(4-(hydroxymethyl)phenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0518905
|
6-(cyclohexylamino)-N-(4-methoxyphenyl)pyrimidine-4-carboxamide
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0526345
|
N-(4-hydroxyphenyl)-6-(N-methylanilino)pyrimidine-4-carboxamide
Show/Hide
|
C18H16N4O2
|
1
|
| 1 |
EC50 > 20000 nM
|
|
|
|
CP0475809
|
3-[6-[(2-chloro-6-ethylphenyl)methoxy]spiro[2H-1-benzofuran-3,3'-piperidine]-1'-yl]propanoic acid;hydrochloride
Show/Hide
|
C24H29Cl2NO4
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0862080
|
3-(6-((2,6-dichloropyridin-4-yl)methoxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C21H23Cl3N2O4
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0863960
|
(E)-3-(6-(2,6-dichlorostyryl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H24Cl3NO3
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0882548
|
3-(6-((2-chlorophenyl)ethynyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H23Cl2NO3
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0931379
|
3-(6-(2,6-dichlorobenzyloxy)-2H-spiro[benzofuran-3,3'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H24Cl3NO4
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0952524
|
3-(6-(benzyloxy)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C22H26ClNO4
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0952542
|
3-(6-(phenylethynyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)propanoic acid hydrochloride
Show/Hide
|
C23H24ClNO3
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0960370
|
2-(6-(2,6-dichlorobenzylsulfonyl)-2H-spiro[benzofuran-3,4'-piperidine]-1'-yl)acetic acid hydrochloride
Show/Hide
|
C21H22Cl3NO5S
|
1
|
| 1 |
EC50 > 31622.78 nM
|
|
|
|
CP0381087
|
3-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]propanoic acid
Show/Hide
|
C22H19NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388429
|
4-[[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]methyl]benzoic acid
Show/Hide
|
C27H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388439
|
5-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]pentanoic acid
Show/Hide
|
C24H23NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0388447
|
4-[(7-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid
Show/Hide
|
C23H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0414869
|
1-[(5-naphthalen-2-yl-1-benzothiophen-2-yl)methyl]azetidine-3-carboxylic acid
Show/Hide
|
C23H19NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0464445
|
4-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]butanoic acid
Show/Hide
|
C23H21NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0464446
|
2-[(4-naphthalen-2-yl-1-benzothiophen-2-yl)methylamino]acetic acid
Show/Hide
|
C21H17NO2S
|
1
|
| 1 |
EC50 > 100000 nM
|
|
|
|
CP0372154
|
(2R,3S,5S)-2-[(hydrogen phosphonatooxy)methyl]-5-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium
Show/Hide
|
C20H34NO5P
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0372156
|
(2R,3S,5S)-5-[(hydrogen phosphonatooxy)methyl]-2-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium
Show/Hide
|
C20H34NO5P
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0372158
|
(2S,3R,5R)-2-[(hydrogen phosphonatooxy)methyl]-5-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium
Show/Hide
|
C20H34NO5P
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0496074
|
(2S,3R,5R)-5-[(hydrogen phosphonatooxy)methyl]-2-(hydroxymethyl)-3-(4-octylphenyl)pyrrolidin-1-ium
Show/Hide
|
C20H34NO5P
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0393723
|
1-(4-(5-(pyridin-3-yl)benzofuran-2-yl)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H20N2O3
|
1
|
| 1 |
EC50 > 1000 nM
|
|
|
|
CP0863137
|
[(1S,3R)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 0.1 nM
|
|
|
|
CP0403977
|
[(1R,3R)-3-amino-1-hydroxy-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C19H34NO4P
|
2
|
| 1 |
IC50 = 0.1 nM
|
|
|
| 2 |
IC50 = 4.8 nM
|
|
|
|
CP0554209
|
US8822510, 4
Show/Hide
|
C27H33FN2O4
|
1
|
| 1 |
IC50 = 0.12 nM
|
|
|
|
CP0392505
|
[(1S,3S)-3-[(4-nonylphenyl)methylamino]cyclohexyl]phosphonic acid
Show/Hide
|
C22H38NO3P
|
1
|
| 1 |
IC50 = 0.16 nM
|
|
|
|
CP0848005
|
[3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 0.16 nM
|
|
|
|
CP0376811
|
3-[(4-nonylphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
2
|
| 1 |
IC50 = 0.2 nM
|
|
|
| 2 |
IC50 = 3.1 nM
|
|
|
|
CP0475389
|
US8822510, 63
Show/Hide
|
C27H30FN3O3
|
1
|
| 1 |
IC50 = 0.21 nM
|
|
|
|
CP0881026
|
3-(N-alkylamino) propylphosphonic acid derivative
Show/Hide
|
C19H36NO5P
|
1
|
| 1 |
IC50 = 0.28 nM
|
|
|
|
CP0398427
|
[2-amino-1-hydroxy-4-(4-octylphenyl)butan-2-yl] dihydrogen phosphate
Show/Hide
|
C18H32NO5P
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0453216
|
3-[(3-chloro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H31ClNO4P
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0506943
|
3-[(4-nonoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0555480
|
US8835470, 74
Show/Hide
|
C25H22F3N5O5
|
1
|
| 1 |
IC50 = 0.3 nM
|
|
|
|
CP0561111
|
US8822510, 18
Show/Hide
|
C27H30FN3O4
|
1
|
| 1 |
IC50 = 0.31 nM
|
|
|
|
CP0403262
|
1-(4-nonylbenzyl)pyrrolidin-3-ylphosphonic acid
Show/Hide
|
C20H34NO3P
|
2
|
| 1 |
IC50 = 0.33 nM
|
|
|
| 2 |
IC50 = 6.9 nM
|
|
|
|
CP0431224
|
1,2,4-oxadiazole based compound, 35
Show/Hide
|
C22H20F3N3O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0436128
|
1,2,4-oxadiazole based compound, 32
Show/Hide
|
C24H25N3O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0404437
|
3-[(3-bromo-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H31BrNO4P
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0453952
|
3-[(3,5-dimethyl-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C20H36NO4P
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0492236
|
3-[(3-bromo-4-decoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C21H37BrNO5P
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0500103
|
US8835470, 6
Show/Hide
|
C27H26F3N5O6
|
1
|
| 1 |
IC50 = 0.46 nM
|
|
|
|
CP0536187
|
US8822510, 9
Show/Hide
|
C28H32FN3O3
|
1
|
| 1 |
IC50 = 0.47 nM
|
|
|
|
CP0377169
|
3-[(3-methyl-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0448991
|
3-[[4-(2-heptyltetrazol-5-yl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C18H30N5O3P
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0498260
|
3-[[4-(5-heptyl-1,2,4-oxadiazol-3-yl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C19H30N3O4P
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0554157
|
US8822510, 98
Show/Hide
|
C28H32ClN3O3
|
1
|
| 1 |
IC50 = 0.54 nM
|
|
|
|
CP0565659
|
US9187437, 32
Show/Hide
|
C21H22ClN3O
|
1
|
| 1 |
IC50 = 0.54 nM
|
|
|
|
CP0419445
|
US9216972, 5
Show/Hide
|
C24H24F3N3O4
|
1
|
| 1 |
IC50 = 0.57 nM
|
|
|
|
CP0374881
|
1,2,4-oxadiazole based compound, 26
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0536141
|
1-(4-((5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)methoxy)benzyl)azetidine-3-carboxylic acid
Show/Hide
|
C24H27N3O4
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0431648
|
3-[(4-octylphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H32NO3P
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0453944
|
3-[(3,5-dichloro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H30Cl2NO4P
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0418259
|
US9216972, 6
Show/Hide
|
C26H20F3N3O4
|
1
|
| 1 |
IC50 = 0.66 nM
|
|
|
|
CP0409210
|
3-[(3-fluoro-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H31FNO4P
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0378761
|
(+/-)-2-(cis-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0465509
|
US8629282, 57
Show/Hide
|
C28H25F3N4O6
|
1
|
| 1 |
IC50 = 0.7 nM
|
|
|
|
CP0409297
|
[2-amino-4-(4-octylphenyl)butyl] dihydrogen phosphate
Show/Hide
|
C18H32NO4P
|
1
|
| 1 |
IC50 = 0.76 nM
|
|
|
|
CP0391846
|
1,2,4-oxadiazole based compound, 37
Show/Hide
|
C24H23F2N3O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0378760
|
(+/-)-2-(cis-5-(4-(5-(4-((S)-3,3-difluorocyclopentyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H25F2N3O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0537313
|
US8835470, 71
Show/Hide
|
C22H17F3N4O5
|
1
|
| 1 |
IC50 = 0.85 nM
|
|
|
|
CP0391844
|
1,2,4-oxadiazole based compound, 36
Show/Hide
|
C24H23F2N3O3
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0382451
|
3-[(4-nonanoylphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H32NO4P
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0404436
|
3-[[4-(4-hexylphenyl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C22H32NO3P
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0490825
|
US9216972, 23
Show/Hide
|
C27H27F3N2O3
|
1
|
| 1 |
IC50 = 0.98 nM
|
|
|
|
CP0384399
|
2-(trans-5-(4-(5-(4-cyclopentylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0402395
|
3-(10-phenyldecylamino)propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0404466
|
3-[(3-bromo-5-methoxy-4-undecoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C22H39BrNO5P
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0419230
|
US9187437, 40
Show/Hide
|
C19H19ClN2O2S
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0418258
|
US9216972, 2
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0378040
|
1,2,4-oxadiazole based compound, 22
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0436191
|
1,2,4-oxadiazole based compound, 23
Show/Hide
|
C22H23N3O3
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0434360
|
3-[(3,5-dibromo-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H30Br2NO4P
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0443361
|
US9216972, 3
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0384397
|
2-(trans-5-(4-(5-(4-cyclohexylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C26H29N3O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0485409
|
1,2,4-oxadiazole based compound, 33
Show/Hide
|
C25H27N3O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0389839
|
3-[(3-bromo-5-methoxy-4-nonoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C20H35BrNO5P
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0457473
|
3-[(4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H32NO4P
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0419446
|
US9216972, 61
Show/Hide
|
C25H18F3N3O5
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0561110
|
US8822510, 11
Show/Hide
|
C28H31N3O4
|
1
|
| 1 |
IC50 = 1.68 nM
|
|
|
|
CP0431223
|
1,2,4-oxadiazole based compound, 34
Show/Hide
|
C25H21N3O3
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0393967
|
1,2,4-oxadiazole based compound, 29
Show/Hide
|
C22H23N3O4
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0551850
|
(1S,2R)-2-[[2-hydroxy-2-[4-[5-(5-phenyl-4-propyl-1,2-oxazol-3-yl)-1,2,4-oxadiazol-3-yl]phenyl]ethyl]amino]cyclopentane-1-carboxylic acid
Show/Hide
|
C28H30N4O5
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0453956
|
3-[(3-methoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO5P
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0476956
|
US9187437, 33
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0384392
|
2-(trans-5-(4-(5-(4-(4,4-difluorocyclohexyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C26H27F2N3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0419093
|
methyl-[3-[(4-nonylphenyl)methylamino]propyl]phosphinic acid
Show/Hide
|
C20H36NO2P
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0378775
|
(+/-)-2-(cis-5-(4-(5-(4-cyclopentyl-3-fluorophenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0512227
|
US8835470, 10
Show/Hide
|
C24H17F3N6O5
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0493568
|
(2S)-4-amino-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]amino]butanoic acid
Show/Hide
|
C27H30ClN3O5S
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0532583
|
US8835470, 126
Show/Hide
|
C24H16F3N5O5
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0384401
|
2-(5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H22F3NO3S
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0446402
|
1,2,4-oxadiazole based compound, 31
Show/Hide
|
C23H23N3O3
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0406502
|
(3-Tetradecylamino-propyl)-phosphonic acid
Show/Hide
|
C17H38NO3P
|
2
|
| 1 |
IC50 = 2.3 nM
|
|
|
| 2 |
IC50 = 3.7 nM
|
|
|
|
CP0409209
|
4-[(3-Phosphono-propylamino)-methyl]-benzoic acid heptyl ester
Show/Hide
|
C18H30NO5P
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0410003
|
3-[(3-methoxy-5-methyl-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C20H36NO5P
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0391327
|
3-[(3-chloro-5-methoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C19H33ClNO5P
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0453571
|
(3-Tridecylamino-propyl)-phosphonic acid
Show/Hide
|
C16H36NO3P
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0463921
|
3-[(3-ethoxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C20H36NO5P
|
1
|
| 1 |
IC50 = 2.5 nM
|
|
|
|
CP0462013
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]amino]propanoic acid
Show/Hide
|
C26H27ClN2O5S
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0512228
|
US8835470, 41
Show/Hide
|
C24H16F3N5O4
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0546515
|
US8835470, 32
Show/Hide
|
C24H20F3N5O5
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0436082
|
(+/-)-2-(cis-5-(4-(5-(4-cyclopentyl-2-fluorophenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C25H26FN3O3
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0393963
|
1,2,4-oxadiazole based compound, 24
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0532582
|
US8835470, 93
Show/Hide
|
C26H22F3N5O6
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0443029
|
US8835470, 62
Show/Hide
|
C22H17F3N4O5
|
1
|
| 1 |
IC50 = 3.2 nM
|
|
|
|
CP0424726
|
(+/-)-2-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0404561
|
US9187437, 7
Show/Hide
|
C22H24N2O
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0475390
|
US8822510, 100
Show/Hide
|
C28H30FN3O3
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0393962
|
1,2,4-oxadiazole based compound, 21
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0431023
|
1,2,4-oxadiazole based compound, 27
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0539339
|
US8629282, 68
Show/Hide
|
C23H17F3N4O6
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0428536
|
3-(3-bromo-5-methoxy-4-(octyloxy)benzylamino)propylphosphonic acid
Show/Hide
|
C19H33BrNO5P
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0450561
|
US9216972, 132
Show/Hide
|
C27H19F3N4O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0393969
|
1,2,4-oxadiazole based compound, 30
Show/Hide
|
C22H21N3O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0378772
|
(+/-)-3-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)propanoic acid
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0450071
|
US8835470, 31
Show/Hide
|
C24H19F3N4O6S
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0575702
|
US8835470, 30
Show/Hide
|
C23H18F3N5O4
|
1
|
| 1 |
IC50 = 4.5 nM
|
|
|
|
CP0532584
|
US8835470, 137
Show/Hide
|
C26H19F3N6O3
|
1
|
| 1 |
IC50 = 4.9 nM
|
|
|
|
CP0485046
|
1,2,4-oxadiazole based compound, 28
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
IC50 = 5.1 nM
|
|
|
|
CP0373301
|
3-[3-(4-heptylphenyl)propylamino]propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 5.3 nM
|
|
|
|
CP0384395
|
2-(trans-5-(4-(5-(4-(3,3,3-trifluoropropyl)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C23H22F3N3O3
|
1
|
| 1 |
IC50 = 5.5 nM
|
|
|
|
CP0465520
|
US9216972, 67
Show/Hide
|
C25H17F4N3O4
|
1
|
| 1 |
IC50 = 5.6 nM
|
|
|
|
CP0384400
|
2-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0378774
|
(+/-)-3-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)propanoic acid
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 = 5.7 nM
|
|
|
|
CP0554815
|
US8822510, 52
Show/Hide
|
C27H31ClN2O4
|
1
|
| 1 |
IC50 = 5.75 nM
|
|
|
|
CP0453512
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]-methylamino]propanoic acid
Show/Hide
|
C27H29ClN2O5S
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0402450
|
3-[2-(4-octylphenyl)ethylamino]propylphosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0380620
|
(3-Pentadecylamino-propyl)-phosphonic acid
Show/Hide
|
C18H40NO3P
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0529028
|
US8629282, 65
Show/Hide
|
C28H25F3N4O6
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0551009
|
US8835470, 17
Show/Hide
|
C24H17F3N6O4
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0465518
|
US9216972, 14
Show/Hide
|
C26H25F3N2O4
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0379285
|
2-[(2R,5S)-5-tetradecylpyrrolidin-2-yl]ethylphosphonic acid
Show/Hide
|
C20H42NO3P
|
1
|
| 1 |
IC50 = 6.9 nM
|
|
|
|
CP0373686
|
(3-Hexadecylamino-propyl)-phosphonic acid
Show/Hide
|
C19H42NO3P
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0421389
|
3-[(3-bromo-4-hexoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C17H29BrNO5P
|
1
|
| 1 |
IC50 = 7.3 nM
|
|
|
|
CP0403608
|
4-(4-Nonyl-benzylamino)-butyric acid
Show/Hide
|
C20H33NO2
|
1
|
| 1 |
IC50 = 7.7 nM
|
|
|
|
CP0390461
|
2-(cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-3-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0378773
|
(+/-)-2-(trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidin-2-yl)acetic acid
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0470169
|
US9187437, 26
Show/Hide
|
C24H28N2O3
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0456422
|
1,2,4-oxadiazole based compound, 13
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 8.2 nM
|
|
|
|
CP0393661
|
[3-amino-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0479544
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]-methylamino]-3-(dimethylamino)propanoic acid
Show/Hide
|
C29H34ClN3O5S
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0503662
|
US8835470, 61
Show/Hide
|
C22H18F3N5O3
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0478347
|
[3-amino-3-(hydroxymethyl)-5-(4-octylphenyl)pentyl]phosphonic acid
Show/Hide
|
C20H36NO4P
|
1
|
| 1 |
IC50 = 8.7 nM
|
|
|
|
CP0500191
|
US8822510, 143
Show/Hide
|
C25H25ClFN3O4
|
1
|
| 1 |
IC50 = 9.72 nM
|
|
|
|
CP0854351
|
hydrogen (3-{[(4-nonylphenyl)methyl]amino}propyl)phosphonite
Show/Hide
|
C19H34NO2P
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0554833
|
(2S)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]amino]-4-(dimethylamino)butanoic acid
Show/Hide
|
C29H34ClN3O5S
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0490263
|
US8629282, 5
Show/Hide
|
C24H19F3N4O6
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0569120
|
US9187437, 5
Show/Hide
|
C22H23FN2O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0450767
|
US8822510, 141
Show/Hide
|
C25H25Cl2N3O4
|
1
|
| 1 |
IC50 = 12.04 nM
|
|
|
|
CP0453348
|
3-[(3-bromo-4-heptoxy-5-methoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H31BrNO5P
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0450096
|
US8835470, 90
Show/Hide
|
C28H19F3N6O4
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0529027
|
US8629282, 30
Show/Hide
|
C26H21F3N4O6
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0531014
|
US9187437, 2
Show/Hide
|
C21H21F2N3O2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0860694
|
[3-Amino-2-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid; compound with [(E)-3-amino-5-(4-octyl-phenyl)-pent-1-enyl]-phosphonic acid
Show/Hide
|
C38H66N2O7P2
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0868637
|
[3-Amino-2-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0413075
|
3-Hydroxy-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
|
C20H33NO3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0437625
|
3-[(3-hydroxy-4-octoxyphenyl)methylamino]propylphosphonic acid
Show/Hide
|
C18H32NO5P
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0483210
|
US8629282, 53
Show/Hide
|
C24H19F3N4O6
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0860724
|
[(1S,3S)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0414924
|
(3-Amino-13-phenyl-tridecyl)-phosphonic acid
Show/Hide
|
C19H34NO3P
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0445772
|
3-[methyl(tetradecyl)amino]propylphosphonic acid
Show/Hide
|
C18H40NO3P
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0419442
|
US9216972, 94
Show/Hide
|
C26H22F3N3O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0850212
|
[(1R,3S)-3-Amino-1-hydroxy-5-(4-octyl-phenyl)-pentyl]-phosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0441771
|
(+/-)-trans-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0503663
|
US8835470, 67
Show/Hide
|
C22H17F3N4O4
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
|
CP0419846
|
1-(4-nonylbenzyl)azetidine-3-carboxylic acid
Show/Hide
|
C20H31NO2
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0374689
|
(3-Amino-heptadecyl)-phosphonic acid
Show/Hide
|
C17H38NO3P
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0405741
|
1-(4-nonylbenzyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C21H33NO2
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0549995
|
(2R)-2-[[4-[3-[(4-chloro-2,5-dimethylphenyl)sulfonylamino]phenyl]-2,6-dimethylbenzoyl]-methylamino]-4-(dimethylamino)butanoic acid
Show/Hide
|
C30H36ClN3O5S
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0507171
|
US8629282, 41
Show/Hide
|
C27H23F3N4O6
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0384390
|
2-Hydroxy-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
|
C20H33NO3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0500337
|
US9216972, 70
Show/Hide
|
C28H24F3N3O4
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0516214
|
US9216972, 93
Show/Hide
|
C26H24F3N3O3
|
1
|
| 1 |
IC50 = 22 nM
|
|
|
|
CP0539338
|
US8629282, 4
Show/Hide
|
C21H15F3N4O4
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0529026
|
US8629282, 25
Show/Hide
|
C26H21F3N4O6
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0519011
|
US9216972, 16
Show/Hide
|
C25H25N3O4
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0446328
|
5-(4-((4-phenyl-5-(trifluoromethyl)thiophen-2-yl)methoxy)phenyl)pyrrolidine-3-carboxylic acid
Show/Hide
|
C23H20F3NO3S
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0418882
|
(3-Amino-hexadecyl)-phosphonic acid
Show/Hide
|
C16H36NO3P
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0419845
|
3-phenyl-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole
Show/Hide
|
C19H11F3N2OS
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0512663
|
US9187437, 17
Show/Hide
|
C22H22F2N2O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0561113
|
US8822510, 88
Show/Hide
|
C28H28F3N3O3
|
1
|
| 1 |
IC50 = 26.71 nM
|
|
|
|
CP0496784
|
1,3,4-oxadiazole based compound, 5
Show/Hide
|
C18H19N3O
|
1
|
| 1 |
IC50 = 27 nM
|
|
|
|
CP0431020
|
1,2,4-oxadiazole based compound, 25
Show/Hide
|
C25H29N3O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0441966
|
US8835470, 88
Show/Hide
|
C25H22F3N5O4
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0532580
|
US8835470, 22
Show/Hide
|
C23H17F3N4O6
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0379112
|
(3-Dodecylamino-propyl)-phosphonic acid
Show/Hide
|
C15H34NO3P
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0872791
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-[(5-hydroxyheptyl)oxy]but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO7S2
|
2
|
| 1 |
IC50 = 31 nM
|
|
|
| 2 |
IC50 = 500 nM
|
|
|
|
CP0544504
|
US8835470, 51
Show/Hide
|
C27H26F3N5O6
|
1
|
| 1 |
IC50 = 31 nM
|
|
|
|
CP0430984
|
3-[[4-(1-hydroxynonyl)phenyl]methylamino]propylphosphonic acid
Show/Hide
|
C19H34NO4P
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0523927
|
US9187437, 8
Show/Hide
|
C23H23F3N2O
|
1
|
| 1 |
IC50 = 33 nM
|
|
|
|
CP0306592
|
5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-3-(3-(trifluoromethyl)phenyl)-1,2,4-oxadiazole
Show/Hide
|
C20H10F6N2OS
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0529025
|
US8629282, 9
Show/Hide
|
C21H15F3N4O4
|
1
|
| 1 |
IC50 = 39 nM
|
|
|
|
CP0447807
|
3-Fluoro-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
|
C20H32FNO2
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0575703
|
US8835470, 132
Show/Hide
|
C26H20F3N5O4
|
1
|
| 1 |
IC50 = 42 nM
|
|
|
|
CP0544505
|
US8835470, 116
Show/Hide
|
C24H19F3N4O4
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0404002
|
2,2-Difluoro-4-(4-nonyl-benzylamino)-butyric acid
Show/Hide
|
C20H31F2NO2
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0551320
|
US8822510, 92
Show/Hide
|
C27H28ClN3O3
|
1
|
| 1 |
IC50 = 45.65 nM
|
|
|
|
CP0393499
|
(3-Hydroxy-1-tetradecyl-pyrrolidin-3-yl)-phosphonic acid
Show/Hide
|
C18H38NO4P
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0916381
|
[Hydroxy-(1-tetradecyl-pyrrolidin-3-yl)-methyl]-phosphonic acid
Show/Hide
|
C19H40NO4P
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0450560
|
US9216972, 20
Show/Hide
|
C25H26N2O3
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0483209
|
US8629282, 50
Show/Hide
|
C27H23F3N4O6
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0226841
|
US9216972, 7
Show/Hide
|
C26H20F3N3O4
|
1
|
| 1 |
IC50 = 57 nM
|
|
|
|
CP0470168
|
US9187437, 34
Show/Hide
|
C21H23N3O2
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0378758
|
(+/-)-cis-5-(4-(5-(4-isobutylphenyl)-1,2,4-oxadiazol-3-yl)phenyl)pyrrolidine-2-carboxylic acid
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 75 nM
|
|
|
|
CP0405742
|
3-(2,4-dichlorophenyl)-5-(4-phenyl-5-(trifluoromethyl)thiophen-2-yl)-1,2,4-oxadiazole
Show/Hide
|
C19H9Cl2F3N2OS
|
1
|
| 1 |
IC50 = 78 nM
|
|
|
|
CP0943776
|
sodium 4-[(4-butoxyphenyl)thio]-20-(1,12-dihydroxydodec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C35H44O6S2
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0373279
|
(3-Amino-octadecyl)-phosphonic acid
Show/Hide
|
C18H40NO3P
|
1
|
| 1 |
IC50 = 85 nM
|
|
|
|
CP0393495
|
2-(1-tetradecylpyrrolidin-2-yl)ethylphosphonic acid
Show/Hide
|
C20H42NO3P
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0419444
|
US9216972, 25
Show/Hide
|
C23H19F3N2O3
|
1
|
| 1 |
IC50 = 94 nM
|
|
|
|
CP0544905
|
US9187437, 30
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0955446
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-[(5-hydroxynonyl)oxy]but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C35H43NaO7S2
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0393959
|
1,3,4-oxadiazole based compound, 9
Show/Hide
|
C23H25N3O3
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0455679
|
1-[[3-chloro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H17ClF3NO3
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0955445
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-[(5-hydroxyundecyl)oxy]but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C37H47NaO7S2
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0555307
|
US8822510, 85
Show/Hide
|
C24H22ClF2N3O4
|
1
|
| 1 |
IC50 = 135.3 nM
|
|
|
|
CP0393677
|
(3-Amino-pentadecyl)-phosphonic acid
Show/Hide
|
C15H34NO3P
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0545008
|
1-[[4-[(3,4-dichlorophenyl)methoxy]-2-methylphenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H19Cl2NO3
|
1
|
| 1 |
IC50 = 166 nM
|
|
|
|
CP0532581
|
US8835470, 86
Show/Hide
|
C29H20F3N5O4
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0882743
|
sodium 4-[(4-butoxyphenyl)thio]-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C35H43NaO5S2
|
2
|
| 1 |
IC50 = 190 nM
|
|
|
| 2 |
IC50 = 1000 nM
|
|
|
|
CP0959558
|
sodium 20-(1-hydroxytridec-2-yn-1-yl)-4-[(4-propoxyphenyl)thio]biphenyl-3-sulfonate
Show/Hide
|
C34H41NaO5S2
|
1
|
| 1 |
IC50 = 190 nM
|
|
|
|
CP0485396
|
3-(2-tridecylpiperidin-1-yl)propylphosphonic acid
Show/Hide
|
C21H44NO3P
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0527331
|
US9187437, 13
Show/Hide
|
C23H22F4N2O
|
1
|
| 1 |
IC50 = 210 nM
|
|
|
|
CP0455680
|
1-[[4-[(3,4-dichlorophenyl)methoxy]-3-fluorophenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C18H16Cl2FNO3
|
1
|
| 1 |
IC50 = 217 nM
|
|
|
|
CP0464605
|
(4-Hydroxy-1-tetradecyl-piperidin-4-yl)-methyl-phosphinic acid
Show/Hide
|
C20H42NO3P
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0556887
|
US9216972, 33
Show/Hide
|
C26H18ClN3O2
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0511184
|
1-[[2-chloro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H17ClF3NO3
|
1
|
| 1 |
IC50 = 256 nM
|
|
|
|
CP0379286
|
(2-Tetradecylamino-cyclohexylmethyl)-phosphonic acid
Show/Hide
|
C21H44NO3P
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0433608
|
(4-Hydroxy-2-tetradecyl-piperidin-4-yl)-methyl-phosphinic acid
Show/Hide
|
C20H42NO3P
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0544506
|
US8835470, 152
Show/Hide
|
C27H26F3N5O4
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0467495
|
1-[[2-methyl-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C20H20F3NO3
|
1
|
| 1 |
IC50 = 333 nM
|
|
|
|
CP0946830
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-[(5-hydroxypentyl)oxy]but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C31H35NaO7S2
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0443095
|
US8835470, 24
Show/Hide
|
C23H19F3N4O4
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0379287
|
(3-Tetradecylamino-cyclopentyl)-phosphonic acid
Show/Hide
|
C19H40NO3P
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0384389
|
3-[4-(4-heptylphenyl)butylamino]propylphosphonic acid
Show/Hide
|
C20H36NO3P
|
1
|
| 1 |
IC50 = 360 nM
|
|
|
|
CP0032773
|
1-[[4-[(3,4-dichlorophenyl)methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C18H17Cl2NO3
|
1
|
| 1 |
IC50 = 362 nM
|
|
|
|
CP0919325
|
sodium 4-[(4-butoxyphenyl)thio]-20-tridec-2-yn-1-ylbiphenyl-3-sulfonate
Show/Hide
|
C35H44NNaO4S2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0419441
|
US9216972, 12
Show/Hide
|
C23H25NO4
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0919327
|
sodium 4-[(4-ethoxyphenyl)thio]-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO5S2
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0959559
|
sodium 4-(4-ethoxyphenoxy)-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO6S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0406156
|
1-[[3-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H17F4NO3
|
1
|
| 1 |
IC50 = 401 nM
|
|
|
|
CP0470166
|
US9187437, 20
Show/Hide
|
C29H29FN2O2
|
1
|
| 1 |
IC50 = 410 nM
|
|
|
|
CP0554210
|
US8822510, 19
Show/Hide
|
C26H26ClN5O4
|
1
|
| 1 |
IC50 = 447.1 nM
|
|
|
|
CP0395057
|
1-[[4-[(3,4-dichlorophenyl)methoxy]-2-fluorophenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C18H16Cl2FNO3
|
1
|
| 1 |
IC50 = 472 nM
|
|
|
|
CP0919326
|
sodium 4-[(4-hexyloxyphenyl)thio]-20-(1-hydroxytridec-2-yl)biphenyl-3-sulfonate
Show/Hide
|
C37H47NaO5S2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0565699
|
US8629282, 39
Show/Hide
|
C29H27F3N4O6
|
1
|
| 1 |
IC50 = 541 nM
|
|
|
|
CP0465521
|
US9216972, 74
Show/Hide
|
C27H24F3N3O4
|
1
|
| 1 |
IC50 = 600 nM
|
|
|
|
CP0491920
|
US9187437, 27
Show/Hide
|
C29H29ClN2O2
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0565716
|
US8629282, 13
Show/Hide
|
C30H29F3N4O6
|
1
|
| 1 |
IC50 = 630 nM
|
|
|
|
CP0071903
|
1-[[2-fluoro-4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H17F4NO3
|
1
|
| 1 |
IC50 = 680 nM
|
|
|
|
CP0941210
|
sodium 20-(1-hydroxytridec-2-yn-1-yl)-4-[(4-methoxyphenyl)thio]biphenyl-3-sulfonate
Show/Hide
|
C32H37NaO5S2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0454272
|
4-Amino-6-(4-octyl-phenyl)-hexanoic acid
Show/Hide
|
C20H33NO2
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0556383
|
US8822510, 108
Show/Hide
|
C25H28N4O4
|
1
|
| 1 |
IC50 = 861.3 nM
|
|
|
|
CP0544502
|
US8835470, 26
Show/Hide
|
C31H26F3N5O5
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0418270
|
US9216972, 22
Show/Hide
|
C26H21F3N4O3
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0886558
|
sodium 4-(4-ethoxyphenoxy)-20-(1-hydroxy-1-methyltridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C36H45NaO5S2
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0444172
|
1-[[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H18F3NO3
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0430889
|
3-(2-tetradecylpyrrolidin-1-yl)propylphosphonic acid
Show/Hide
|
C21H44NO3P
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0946832
|
sodium 2-(4-ethoxyphenoxy)-5-[3-(1-hydroxytridec-2-yn-1-yl)-2-thienyl]benzenesulfonate
Show/Hide
|
C31H37NaO6S2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0458147
|
US9187437, 1
Show/Hide
|
C22H23F2N3O2
|
1
|
| 1 |
IC50 = 1300 nM
|
|
|
|
CP0403972
|
(3-Amino-henicosyl)-phosphonic acid
Show/Hide
|
C21H46NO3P
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0463922
|
US9216972, 41
Show/Hide
|
C21H21NO2
|
1
|
| 1 |
IC50 = 1600 nM
|
|
|
|
CP0454291
|
3-Amino-5-(4-octyl-phenyl)-pentane-1-sulfonic acid
Show/Hide
|
C19H33NO3S
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0487372
|
3-Amino-5-(4-octyl-phenyl)-pentanoic acid
Show/Hide
|
C19H31NO2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0517177
|
US9216972, 24
Show/Hide
|
C19H14F3NO2
|
1
|
| 1 |
IC50 = 3200 nM
|
|
|
|
CP0397294
|
1-[(2-methyl-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
Show/Hide
|
C19H21NO3
|
1
|
| 1 |
IC50 = 4170 nM
|
|
|
|
CP0933189
|
sodium 4-(4-ethoxyphenoxy)-30-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO6S
|
1
|
| 1 |
IC50 = 4600 nM
|
|
|
|
CP0939710
|
sodium 2-(4-ethoxyphenoxy)-5-[5-(1-hydroxytridec-2-yn-1-yl)-2-thienyl]benzenesulfonate
Show/Hide
|
C31H37NaO6S2
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0939711
|
sodium 4-(2-ethoxyphenoxy)-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO6S
|
1
|
| 1 |
IC50 = 8900 nM
|
|
|
|
CP0420583
|
1-[(3-fluoro-4-phenylmethoxyphenyl)methyl]azetidine-3-carboxylic acid
Show/Hide
|
C18H18FNO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0491921
|
US9187437, 42 (comparative)
Show/Hide
|
C20H20N2O
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0503614
|
US9216972, 32
Show/Hide
|
C20H14N2O3
|
1
|
| 1 |
IC50 = 15000 nM
|
|
|
|
CP0946831
|
sodium 4-(3-ethoxyphenoxy)-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C33H39NaO6S
|
1
|
| 1 |
IC50 > 17000 nM
|
|
|
|
CP0948515
|
2-(4-ethoxyphenoxy)-5-(3-octadecyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl)benzenesulfonate
Show/Hide
|
C34H49N2NaO6S
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0488667
|
2-[1-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]indazol-3-yl]acetic acid
Show/Hide
|
C19H18ClN3O5
|
1
|
| 1 |
IC50 > 19900 nM
|
|
|
|
CP0549925
|
2-[3-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]indol-1-yl]acetic acid
Show/Hide
|
C20H19ClN2O5
|
1
|
| 1 |
IC50 > 19900 nM
|
|
|
|
CP0549999
|
N-(5-chloro-2,4-dimethoxyphenyl)-2-(1-methylindol-3-yl)acetamide
Show/Hide
|
C19H19ClN2O3
|
1
|
| 1 |
IC50 > 19900 nM
|
|
|
|
CP0555283
|
2-[4-[2-(5-chloro-2,4-dimethoxyanilino)-2-oxoethyl]-1-oxophthalazin-2-yl]acetic acid
Show/Hide
|
C20H18ClN3O6
|
1
|
| 1 |
IC50 > 19900 nM
|
|
|
|
CP0943775
|
sodium 4-[(4-butoxyphenyl)thio]-20-[1-hydroxy-4-(3-hydroxypropoxy)but-2-yn-1-yl]biphenyl-3-sulfonate
Show/Hide
|
C29H31NaO7S2
|
1
|
| 1 |
IC50 > 20000 nM
|
|
|
|
CP0875516
|
sodium 4-[(4-octyloxyphenyl)thio]-20-(1-hydroxytridec-2-yn-1-yl)biphenyl-3-sulfonate
Show/Hide
|
C39H51NaO5S2
|
1
|
| 1 |
IC50 > 2400 nM
|
|
|
|
CP0939709
|
20-(1-aminotridec-2-yn-1-yl)-4-[(4-butoxyphenyl)thio]biphenyl-3-sulfonate
Show/Hide
|
C35H43NaO4S2
|
1
|
| 1 |
IC50 > 8100 nM
|
|
|
|
CP0575959
|
US8802663, 120
Show/Hide
|
C25H31N5O4
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0506912
|
US8741923, 35
Show/Hide
|
C29H29N3O4
|
1
|
| 1 |
Ki = 0.23 nM
|
|
|
|
CP0488390
|
US8741923, 36
Show/Hide
|
C27H22F3N3O3
|
1
|
| 1 |
Ki = 0.49 nM
|
|
|
|
CP0553833
|
US8802663, 125
Show/Hide
|
C28H35N5O4
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0442334
|
US8741923, 39
Show/Hide
|
C28H24F3N3O3
|
1
|
| 1 |
Ki = 0.6 nM
|
|
|
|
CP0491113
|
US8802663, 97
Show/Hide
|
C27H33N5O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0510207
|
US8741923, 16
Show/Hide
|
C28H27N3O4
|
1
|
| 1 |
Ki = 0.7 nM
|
|
|
|
CP0488391
|
US8741923, 37
Show/Hide
|
C27H29F3N4O3
|
1
|
| 1 |
Ki = 0.75 nM
|
|
|
|
CP0491115
|
US8802663, 102
Show/Hide
|
C26H33N5O4
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0560620
|
US8741923, 38
Show/Hide
|
C26H27F3N4O3
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0563336
|
US8741923, 12
Show/Hide
|
C24H25N5O
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0470329
|
US8889668, I60
Show/Hide
|
C21H19F4N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0969644
|
US8889668, I32
Show/Hide
|
C21H21FN4O4
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0532596
|
US8741923, 15
Show/Hide
|
C26H25N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0562990
|
US8741923, 40
Show/Hide
|
C29H29N3O4
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0442960
|
US8802663, 101
Show/Hide
|
C25H24N6O3
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0554156
|
US8889668, I57
Show/Hide
|
C21H15F3N2O2S
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0940926
|
US8889668, I26
Show/Hide
|
C22H17N3O4
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0503781
|
US8802663, 117
Show/Hide
|
C22H26N4O3
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0516799
|
US8802663, 79
Show/Hide
|
C25H26N6O3
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0441628
|
US8889668, I35
Show/Hide
|
C22H22F3N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0512239
|
US8889668, I25
Show/Hide
|
C21H18N2O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0531828
|
US8889668, I63
Show/Hide
|
C22H21F4N3O2
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0491111
|
US8802663, 8
Show/Hide
|
C21H18F2N4O
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0510206
|
US8741923, 10
Show/Hide
|
C24H25F3N4O
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0533652
|
US8741923, 24
Show/Hide
|
C21H16N4O2S
|
1
|
| 1 |
Ki = 3 nM
|
|
|
|
CP0402618
|
US9150519, 1-55
Show/Hide
|
C21H29N5O4S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0484459
|
US8802663, 152
Show/Hide
|
C24H22N6O
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0500146
|
US8802663, 150
Show/Hide
|
C24H23N9O
|
1
|
| 1 |
Ki = 3.4 nM
|
|
|
|
CP0442930
|
US8889668, I71
Show/Hide
|
C22H21FN4O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0442931
|
US8889668, I78
Show/Hide
|
C25H24FN3O2
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0519157
|
US8889668, I70
Show/Hide
|
C21H12F6N2O2S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0553818
|
US8889668, I48
Show/Hide
|
C21H18N2O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0450064
|
US8741923, 11
Show/Hide
|
C24H29N5O3S
|
1
|
| 1 |
Ki = 4 nM
|
|
|
|
CP0564048
|
US8741923, 27
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
Ki = 4.26 nM
|
|
|
|
CP0550093
|
US8802663, 151
Show/Hide
|
C26H26N8O
|
1
|
| 1 |
Ki = 4.6 nM
|
|
|
|
CP0520261
|
US8889668, I44
Show/Hide
|
C21H15F3N2O2S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0557319
|
US8889668, I34
Show/Hide
|
C22H19F6N3O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0503701
|
US8802663, 9
Show/Hide
|
C23H16FN5O3S
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0520665
|
US8802663, 23
Show/Hide
|
C22H19F2N5O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0560618
|
US8741923, 5
Show/Hide
|
C25H23N5O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0565709
|
US8741923, 4
Show/Hide
|
C24H20N4O2
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0565718
|
US8741923, 1
Show/Hide
|
C22H20F3N5O
|
1
|
| 1 |
Ki = 5 nM
|
|
|
|
CP0424141
|
US8889668, I74
Show/Hide
|
C21H23FN4O2
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0442121
|
US8802663, 155
Show/Hide
|
C24H23N9O
|
1
|
| 1 |
Ki = 6 nM
|
|
|
|
CP0491112
|
US8802663, 96
Show/Hide
|
C25H31N5O4
|
1
|
| 1 |
Ki = 6.5 nM
|
|
|
|
CP0506754
|
US8889668, I18
Show/Hide
|
C20H18F3N3O3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0575958
|
US8802663, 12
Show/Hide
|
C21H18F2N4O
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0419456
|
US9150519, 1-56
Show/Hide
|
C19H25N5O3S
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0559136
|
US9150519, 1-84
Show/Hide
|
C26H33N5O3
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0442929
|
US8889668, I21
Show/Hide
|
C23H17F3N2O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0479394
|
US8889668, I55
Show/Hide
|
C23H14F6N2O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0521297
|
US8889668, I62
Show/Hide
|
C23H17F3N2O2
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0442138
|
US8802663, 3
Show/Hide
|
C23H14F2N4O
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0569539
|
US9150519, 1-100
Show/Hide
|
C22H29N5O3
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0520664
|
US8802663, 19
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0530623
|
US8802663, 11
Show/Hide
|
C23H20F2N4O
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0569535
|
US9150519, 1-97
Show/Hide
|
C23H31N5O3
|
1
|
| 1 |
Ki = 9 nM
|
|
|
|
CP0484458
|
US8802663, 146
Show/Hide
|
C23H27N5O5
|
1
|
| 1 |
Ki = 9.9 nM
|
|
|
|
CP0556923
|
US9150519, 1-69
Show/Hide
|
C21H26N6O
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0549960
|
US8889668, I1
Show/Hide
|
C20H20N4O4
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0563381
|
US8741923, 25
Show/Hide
|
C23H18N4O
|
1
|
| 1 |
Ki = 11 nM
|
|
|
|
CP0520663
|
US8802663, 5
Show/Hide
|
C24H16F2N4O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0536249
|
US8802663, 6
Show/Hide
|
C23H13F3N4O
|
1
|
| 1 |
Ki = 13 nM
|
|
|
|
CP0531827
|
US8889668, I23
Show/Hide
|
C23H14F6N2O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0577824
|
US8889668, I20
Show/Hide
|
C23H20N2O2
|
1
|
| 1 |
Ki = 16 nM
|
|
|
|
CP0531826
|
US8889668, I2
Show/Hide
|
C19H18N4O5
|
1
|
| 1 |
Ki = 18 nM
|
|
|
|
CP0577825
|
US8889668, I27
Show/Hide
|
C21H22N2O2
|
1
|
| 1 |
Ki = 20 nM
|
|
|
|
CP0516798
|
US8802663, 13
Show/Hide
|
C21H16F2N4O3
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0419457
|
US9150519, 1-90
Show/Hide
|
C19H22N6O2
|
1
|
| 1 |
Ki = 23 nM
|
|
|
|
CP0470328
|
US8889668, I29
Show/Hide
|
C21H19F3N2O2
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0503782
|
US8802663, 138
Show/Hide
|
C20H24N4O3
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0565580
|
US9150519, 1-113
Show/Hide
|
C20H23N5O
|
1
|
| 1 |
Ki = 25 nM
|
|
|
|
CP0539110
|
US8802663, 153
Show/Hide
|
C27H25N7O3
|
1
|
| 1 |
Ki = 28 nM
|
|
|
|
CP0484457
|
US8802663, 144
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
Ki = 31 nM
|
|
|
|
CP0516800
|
US8802663, 105
Show/Hide
|
C26H28N6O3
|
1
|
| 1 |
Ki = 34 nM
|
|
|
|
CP0515719
|
US8741923, 3
Show/Hide
|
C21H22N6O
|
1
|
| 1 |
Ki = 38 nM
|
|
|
|
CP0508926
|
US8889668, I33
Show/Hide
|
C23H19FN2O2
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0569534
|
US9150519, 1-85
Show/Hide
|
C20H26N4O2
|
1
|
| 1 |
Ki = 43 nM
|
|
|
|
CP0519158
|
US8889668, I72
Show/Hide
|
C22H25FN4O4S
|
1
|
| 1 |
Ki = 46 nM
|
|
|
|
CP0554188
|
US8889668, I77
Show/Hide
|
C23H19FN2O3
|
1
|
| 1 |
Ki = 53 nM
|
|
|
|
CP0577826
|
US8889668, I61
Show/Hide
|
C21H17F6N3O2
|
1
|
| 1 |
Ki = 54 nM
|
|
|
|
CP0553832
|
US8802663, 38
Show/Hide
|
C23H21N7O
|
1
|
| 1 |
Ki = 68 nM
|
|
|
|
CP0443668
|
US8802663, 154
Show/Hide
|
C24H23N9O
|
1
|
| 1 |
Ki = 76 nM
|
|
|
|
CP0554187
|
US8889668, I28
Show/Hide
|
C19H20N2O2
|
1
|
| 1 |
Ki = 91 nM
|
|
|
|
CP0536251
|
US8802663, 145
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
Ki = 116 nM
|
|
|
|
CP0551308
|
US8802663, 133
Show/Hide
|
C24H30N4O5
|
1
|
| 1 |
Ki = 122 nM
|
|
|
|
CP0536250
|
US8802663, 134
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
Ki = 128 nM
|
|
|
|
CP0560619
|
US8741923, 22
Show/Hide
|
C23H25N5O3S
|
1
|
| 1 |
Ki = 164 nM
|
|
|
|
CP0484456
|
US8802663, 141
Show/Hide
|
C23H28N4O5
|
1
|
| 1 |
Ki = 180 nM
|
|
|
|
CP0553834
|
US8802663, 142
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
Ki = 191 nM
|
|
|
|
CP0555395
|
US8802663, 140
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
Ki = 253 nM
|
|
|
|
CP0520666
|
US8802663, 147
Show/Hide
|
C23H27N5O5
|
1
|
| 1 |
Ki = 257 nM
|
|
|
|
CP0536247
|
US8802663, 1
Show/Hide
|
C19H14F2N4O2
|
1
|
| 1 |
Ki = 272 nM
|
|
|
|
CP0516801
|
US8802663, 139
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
Ki = 393 nM
|
|
|
|
CP0491114
|
US8802663, 98
Show/Hide
|
C22H24N4O4
|
1
|
| 1 |
Ki = 409 nM
|
|
|
|
CP0561486
|
US9150519, 1-6
Show/Hide
|
C17H19ClN4O2
|
1
|
| 1 |
Ki = 500 nM
|
|
|
|
CP0519541
|
US9150519, 1-5
Show/Hide
|
C21H22N4O2
|
1
|
| 1 |
Ki = 540 nM
|
|
|
|
CP0402615
|
US9150519, 1-9
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 650 nM
|
|
|
|
CP0547699
|
US8889668, I3
Show/Hide
|
C20H18F3N3O2
|
1
|
| 1 |
Ki = 652 nM
|
|
|
|
CP0569533
|
US9150519, 1-10
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
Ki = 740 nM
|
|
|
|
CP0494868
|
US9150519, 1-4
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 980 nM
|
|
|
|
CP0490136
|
US9150519, 1-64
Show/Hide
|
C24H33N5O3S
|
1
|
| 1 |
Ki = 1020 nM
|
|
|
|
CP0509004
|
US8889668, I4
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
Ki = 1074 nM
|
|
|
|
CP0557750
|
US9150519, 1-86
Show/Hide
|
C29H41N5O5S
|
1
|
| 1 |
Ki = 2455 nM
|
|
|
|
CP0413500
|
US9150519, 1-2
Show/Hide
|
C18H22N4O2
|
1
|
| 1 |
Ki = 3230 nM
|
|
|
|
CP0419453
|
US9150519, 1-12
Show/Hide
|
C16H19N5O
|
1
|
| 1 |
Ki = 3360 nM
|
|
|
|
CP0557415
|
US9150519, 1-11
Show/Hide
|
C17H18Cl2N4O2
|
1
|
| 1 |
Ki = 3450 nM
|
|
|
