Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(4-hydroxyphenyl)-6-(2-methylanilino)pyrimidine-4-carboxamide
    Show/Hide
 PubChem ID
CID: 25182757
SID: 57290436
Canonical SMILES
Cc1ccccc1Nc1cc(ncn1)C(=O)Nc1ccc(O)cc1
    Show/Hide
Compound Formula C18H16N4O2
Compound Structure
Protein Name
 Protein Info 
Sphingosine 1-phosphate receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
EDG receptor
Uniprot ID
P21453
Gene Name
S1PR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 2100 nM
   TI
   LI
   LO
   TS
2
Ki = 840 nM
   TI
   LI
   LO
   TS