Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT01108 , 11-beta-hydroxysteroid dehydrogenase type 2
Gene Name HSD11B2
Organism Homo sapiens, Human
Protein Classification Enzyme
Uniprot ID P80365
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT01108
 
Compound ID Compound Name Compound Formula
CP0423421
2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxycyclopentyl)-5-methylthiazol-4(5H)-one
   Show/Hide
C17H21FN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0450736
2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxycyclobutyl)-5-methylthiazol-4(5H)-one
   Show/Hide
C16H19FN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0452528
2-[(S)-1-(2-Chlorophenyl)ethylamino]-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one
   Show/Hide
C15H19ClN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0461516
2-[(S)-1-(2-Fluorophenyl)ethylamino]-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one
   Show/Hide
C15H19FN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0498890
(S)-5-(2-Hydroxypropan-2-yl)-5-methyl-2-{1-[2-(trifluoromethyl)-phenyl]ethylamino}thiazol-4(5H)-one
   Show/Hide
C16H19F3N2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0535206
2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxypropan-2-yl)-5-methylthiazol-4(5H)-one
   Show/Hide
C15H19FN2O2S
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0093362
(6S)-3-[(1S)-1-[4-(2,4-difluorophenyl)phenyl]ethyl]-6-(4-fluorophenyl)-6-(2-hydroxyethyl)-1,3-oxazinan-2-one
   Show/Hide
C26H24F3NO3
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0067583
(2R)-3,3,3-trifluoro-2-[5-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylthiophen-2-yl]-2-hydroxypropanamide
   Show/Hide
C19H18F7N3O4S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0450251
(2R)-3,3,3-trifluoro-2-[3-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylphenyl]-2-hydroxypropanamide
   Show/Hide
C21H20F7N3O4S
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0483438
(2S)-1,1,1-trifluoro-2-[5-[(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl]sulfonylthiophen-2-yl]propan-2-ol
   Show/Hide
C19H19F7N2O3S2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS