Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00915 , Peroxisome proliferator-activated receptor gamma
Gene Name PPARG
Organism Homo sapiens, Human
Protein Classification Transcription factor
Uniprot ID P37231
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT00915
 
Compound ID Compound Name Compound Formula
CP0476740
(E)-2-methyl-2-(3-(2-(2-(4-methylbenzoyl)-1H-benzo[d]imidazol-1-yl)vinyl)phenoxy)propanoic acid
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C27H24N2O4
 1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CP0041219
Actos
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C19H20N2O3S
 2
1
EC50 = 140 nM
   TI
   LI
   LO
   TS
2
EC50 = 390 nM
   TI
   LI
   LO
   TS
CP0398828
4'-[(2-Propyl-1H-naphth[2,3-d]imidazol-1-yl)methyl]-biphenyl-2-carboxylic acid
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C28H24N2O2
 1
1
EC50 = 260 nM
   TI
   LI
   LO
   TS
CP0384187
4'-[(5,6-Dibromo-2-propyl-1H-benzo[d]imidazol-1-yl)-methyl]-biphenyl-2-carboxylic acid
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C24H20Br2N2O2
 1
1
EC50 = 400 nM
   TI
   LI
   LO
   TS
CP0519147
4'-[(5-Bromo-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]-biphenyl-2-carboxylic acid
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C24H21BrN2O2
 1
1
EC50 = 400 nM
   TI
   LI
   LO
   TS
CP0398825
4'-[(6-Bromo-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]-biphenyl-2-carboxylic acid
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C24H21BrN2O2
 1
1
EC50 = 470 nM
   TI
   LI
   LO
   TS
CP0567888
2-[3-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]-4-methylphenyl]acetic acid
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C23H25ClN2O3S
 1
1
EC50 = 542 nM
   TI
   LI
   LO
   TS
CP0487817
4'-[(5-(Phenylcarbonyl)-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]biphenyl-2-carboxylic acid
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C31H26N2O3
 1
1
EC50 = 580 nM
   TI
   LI
   LO
   TS
CP0436545
4'-[(6-(Phenylcarbonyl)-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]biphenyl-2-carboxylic acid
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C31H26N2O3
 1
1
EC50 = 620 nM
   TI
   LI
   LO
   TS
CP0546937
2-[3-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]-4-ethylphenyl]acetic acid
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C24H27ClN2O3S
 1
1
EC50 = 680 nM
   TI
   LI
   LO
   TS
CP0569005
2-[5-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]-2-methylphenyl]acetic acid
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C23H25ClN2O3S
 1
1
EC50 = 980 nM
   TI
   LI
   LO
   TS
CP0544776
2-[4-chloro-3-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]phenyl]acetic acid
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C22H22Cl2N2O3S
 1
1
EC50 = 987 nM
   TI
   LI
   LO
   TS
CP0546461
2-[3-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]-5-methylphenyl]acetic acid
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C23H25ClN2O3S
 1
1
EC50 = 1070 nM
   TI
   LI
   LO
   TS
CP0476738
(E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imidazol-1-yl)prop-1-enyl)phenoxy)propanoic acid
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C28H26N2O4
 1
1
EC50 = 1700 nM
   TI
   LI
   LO
   TS
CP0249320
4'-[(2-Propyl-1H-benzo[d]imidazol-1-yl)methyl]biphenyl-2-carboxylic acid
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C24H22N2O2
 1
1
EC50 = 1900 nM
   TI
   LI
   LO
   TS
CP0459099
3-[2-(3-chlorophenyl)-1H-indol-5-yl]propanoic acid
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C17H14ClNO2
 1
1
EC50 = 2400 nM
   TI
   LI
   LO
   TS
CP0576415
2-[3-[2-[1-(6-chloro-1,3-benzothiazol-2-yl)piperidin-4-yl]ethoxy]phenyl]acetic acid
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C22H23ClN2O3S
 1
1
EC50 = 2580 nM
   TI
   LI
   LO
   TS
CP0373583
4'-[(5-(Hydroxy(phenyl)methyl)-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]biphenyl-2-carboxylic acid
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C31H28N2O3
 1
1
EC50 = 2900 nM
   TI
   LI
   LO
   TS
CP0460640
(E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-4,5,6,7-tetrahydro-1H-benzo[d]imidazol-1-yl)prop-1-enyl)phenoxy)propanoic acid
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C28H30N2O4
 1
1
EC50 = 3000 nM
   TI
   LI
   LO
   TS
CP0467661
2-methyl-2-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imidazol-1-yl)phenoxy)propanoic acid
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C25H22N2O4
 1
1
EC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0083167
4'-((1,4'-dimethyl-2'-propyl(2,6'-bi-1H-benzimidazol)-1'-yl)methyl)-(1,1'-biphenyl)-2-carboxylic acid
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C33H30N4O2
 1
1
EC50 = 3400 nM
   TI
   LI
   LO
   TS
CP0477611
4'-[(6-(Hydroxy(phenyl)methyl)-2-propyl-1H-benzo[d]imidazol-1-yl)methyl]biphenyl-2-carboxylic acid
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C31H28N2O3
 1
1
EC50 = 3500 nM
   TI
   LI
   LO
   TS
CP0039118
2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-5-yl}methyl)sulfanyl]phenoxy}acetic acid
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C21H18F3NO3S2
 1
1
EC50 = 4400 nM
   TI
   LI
   LO
   TS
CP0505065
(E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-benzo[d]imidazol-1-yl)prop-1-enyl)phenoxy)acetic acid
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C26H22N2O4
 1
1
EC50 = 4600 nM
   TI
   LI
   LO
   TS
CP0478675
(E)-2-(3-(3-(4,5-dimethyl-2-(4-methylbenzoyl)-1H-imidazol-1-yl)prop-1-enyl)phenoxy)-2-methylpropanoic acid
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C26H28N2O4
 1
1
EC50 = 4800 nM
   TI
   LI
   LO
   TS
CP0476739
2-methyl-2-(3-((2-(4-methylbenzoyl)-1H-benzo[d]imidazol-1-yl)methyl)phenoxy)propanoic acid
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C26H24N2O4
 1
1
EC50 = 6000 nM
   TI
   LI
   LO
   TS
CP0522045
(E)-2-(3-(3-(2-(4-methylbenzoyl)-1H-imidazol-1-yl)prop-1-enyl)phenoxy)acetic acid
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C22H20N2O4
 1
1
EC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0501573
(E)-2-methyl-2-(3-(3-(2-(4-methylbenzoyl)-1H-imidazol-1-yl)prop-1-enyl)phenoxy)propanoic acid
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C24H24N2O4
 1
1
EC50 = 12000 nM
   TI
   LI
   LO
   TS
CP0514814
3-[2-(4-chloro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
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C18H16ClNO2
 1
1
EC50 = 27770 nM
   TI
   LI
   LO
   TS
CP0402726
3-[2-(2-methylpyridin-3-yl)-1H-indol-5-yl]propanoic acid
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C17H16N2O2
 1
1
EC50 = 56900 nM
   TI
   LI
   LO
   TS
CP0551567
3-[2-(4-fluoro-2-methylphenyl)-1H-indol-5-yl]propanoic acid
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C18H16FNO2
 1
1
EC50 = 56940 nM
   TI
   LI
   LO
   TS
CP0362425
2-chloro-N-[2-(4-ethylphenyl)-1,3-benzoxazol-5-yl]-5-nitrobenzamide
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C22H16ClN3O4
 1
1
IC50 = 0.4 nM
   TI
   LI
   LO
   TS
CP0543193
2-bromo-N-[2-(4-ethylphenyl)-1,3-benzoxazol-5-yl]-5-nitrobenzamide
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C22H16BrN3O4
 1
1
IC50 = 6.3 nM
   TI
   LI
   LO
   TS