Brief Information of the Cell Line and Protein
Cell Line ID: CL000011 , CHO
Synonyms
Chinese Hamster Ovary
CHO-ori
Category Spontaneously immortalized cell line
Organism
Cricetulus griseus (Chinese hamster)
Cellosaurus ID
CVCL_0213
Protein ID: PT00654 , Lysophosphatidic acid receptor 5
Gene Name LPAR5
Organism Rattus norvegicus, Rat
Protein Classification Unclassified protein
Uniprot ID D4ADR1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000011  Protein ID: PT00654
 
Compound ID Compound Name Compound Formula
CP0408712
4-(azepane-1-carbonyl)-2-(1-ethyl-2,3-dihydroindol-6-yl)-6,7-dimethoxyisoquinolin-1-one
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C28H33N3O4
 1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS
CP0444436
2-(1-ethyl-2,3-dihydroindol-6-yl)-4-(4-fluoropiperidine-1-carbonyl)-6,7-dimethoxyisoquinolin-1-one
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C27H30FN3O4
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0963675
4-(Azepan-1-ylcarbonyl)-2-[3-(dimethylamino)phenyl]-6,7-dimethoxyisoquinolin-1(2H)-one hydrochloride
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C26H32ClN3O4
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0556659
4-(azepane-1-carbonyl)-2-(4-ethylphenyl)-6,7-dimethoxyisoquinolin-1-one
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C26H30N2O4
 1
1
IC50 = 570 nM
   TI
   LI
   LO
   TS
CP0541326
4-(azepane-1-carbonyl)-2-(3,4-dimethylphenyl)-6,7-dimethoxyisoquinolin-1-one
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C26H30N2O4
 1
1
IC50 = 720 nM
   TI
   LI
   LO
   TS
CP0422902
2-(4-ethoxyphenyl)-4-(4-fluoropiperidine-1-carbonyl)-6,7-dimethoxyisoquinolin-1-one
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C25H27FN2O5
 1
1
IC50 = 750 nM
   TI
   LI
   LO
   TS
CP0568901
4-(azepan-1-ylcarbonyl)-2-(4-ethoxyphenyl)-6,7-dimethoxy-isoquinolin-1-one
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C26H30N2O5
 1
1
IC50 = 1800 nM
   TI
   LI
   LO
   TS
CP0562553
2-(4-ethoxyphenyl)-N-hexyl-6,7-dimethoxy-N-methyl-1-oxoisoquinoline-4-carboxamide
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C27H34N2O5
 1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
CP0408711
4-(azepane-1-carbonyl)-6,7-dimethoxy-2-propan-2-ylisoquinolin-1-one
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C21H28N2O4
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0558199
4-[4-(azepane-1-carbonyl)-6,7-dimethoxy-1-oxoisoquinolin-2-yl]benzamide
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C25H27N3O5
 1
1
IC50 > 30000 nM
   TI
   LI
   LO
   TS
CP0545957
4-(azepane-1-carbonyl)-2-(4-fluorophenyl)-6,7-dimethoxyisoquinolin-1-one
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C24H25FN2O4
 1
1
IC50 > 3000 nM
   TI
   LI
   LO
   TS