Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT06387 , Solute carrier family 2, facilitated glucose transporter member 3
Gene Name SLC2A3
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P11169
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT06387
 
Compound ID Compound Name Compound Formula
CP0942301
4-((2-(4-chlorophenyl)-6-(4-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)morpholine
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C24H21ClFN3O
 1
1
IC50 = 100000 nM
   TI
   LI
   LO
   TS
CP0853908
2-((2-(4-chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl)methyl)hexahydropyrrolo[1,2-a]pyrazin-6(7H)-one
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C23H24ClN5O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0853912
(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)(pyrazin-2-yl)methanone
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C25H23Cl2N7O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0853946
N-(2-(4-chlorophenyl)-3-((4-(oxetane-3-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
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C24H28ClN5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0853947
1-(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)-2-hydroxyethanone
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C22H23Cl2N5O2
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0853950
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-methylpropane-2-sulfonamide
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C24H30ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0855308
4-((2-(4-chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)morpholine
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C24H20ClF2N3O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0855319
4-((2-(4-chlorophenyl)-6-(2,6-difluorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)morpholine
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C23H19ClF2N4O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0855326
(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)(thiazol-4-yl)methanone
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C24H22Cl2N6OS
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0855327
1-(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)-2-hydroxy-2-methylpropan-1-one
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C24H27Cl2N5O2
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0855329
1-{4-[2-(2,4-Dichloro-phenyl)-6-(1,1-dioxo-1lambda(6)-isothiazolidin-2-yl)-imidazo[1,2-a]pyridin-3-ylmethyl]-piperazin-1-yl}-ethanone
   Show/Hide
C23H25Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0860757
4-((2-(4-chlorophenyl)-6-(2-fluorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)morpholine
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C24H21ClFN3O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0860764
4-((2-(2,4-dichlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl)methyl)morpholine
   Show/Hide
C24H21Cl2N3O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0860766
1-(4-((2-(4-chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)ethanone
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C22H24ClN5O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0860798
N-(2-(2,4-dichlorophenyl)-3-((3-oxopiperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
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C20H21Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0860844
2-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)benzonitrile
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C27H24ClN5O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0875312
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
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C22H25Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0883740
N-(2-(2,4-dichlorophenyl)-3-((6-oxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
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C23H25Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0883743
4-((6-(2-chlorophenyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)morpholine
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C24H21Cl2N3O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0883755
N-(2-(2,4-dichlorophenyl)-3-((4-(1-methyl-1H-pyrazole-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C24H25Cl2N7O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0883787
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-methylpropane-1-sulfonamide
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C24H30ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0887582
1-(4-((2-(4-chlorophenyl)-6-(isopropylsulfonyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperazin-1-yl)ethanone
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C23H27ClN4O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0887654
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-(difluoromethyl)methanesulfonamide
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C22H23Cl2F2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891108
N-(2-(4-chlorophenyl)-3-((4-(2-methoxyacetyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C23H28ClN5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891110
N-(2-(4-chlorophenyl)-3-((4-(pyridazine-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
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C25H26ClN7O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891111
1-(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)-2-methoxyethanone
   Show/Hide
C23H25Cl2N5O2
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891112
4-((2-(2,4-dichlorophenyl)-6-isopropylimidazo[1,2-a]pyrazin-3-yl)methyl)morpholine
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C20H22Cl2N4O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891113
N-(2-(2,4-dichlorophenyl)-3-((4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C24H29Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891136
(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)(pyridazin-4-yl)methanone
   Show/Hide
C25H23Cl2N7O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0891138
N-(2-(2,4-dichlorophenyl)-3-((4-(pyridazine-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C24H23Cl2N7O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0893164
(4-((2-(4-chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)(pyridin-4-yl)methanone
   Show/Hide
C26H25ClN6O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0893168
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-methylethanesulfonamide
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C23H28ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0893171
(4-((2-(4-chlorophenyl)-6-phenylimidazo[1,2-a]pyridin-3-yl)methyl)piperazin-1-yl)(3-fluorophenyl)methanone
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C31H26ClFN4O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0893179
1-{4-[2-(4-Chloro-phenyl)-6-(1,1-dioxo-1lambda(6)-[1,2]thiazinan-2-yl)-imidazo[1,2-a]pyridin-3-ylmethyl]-piperazin-1-yl}-ethanone
   Show/Hide
C24H28ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0893519
N-(2-(2,4-dichlorophenyl)-3-((4-(oxetane-3-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C23H25Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0899448
N-(2-(2,4-dichlorophenyl)-3-((4-(2-methoxyacetyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C22H25Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0903035
N-(2-(4-chlorophenyl)-3-(morpholinomethyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C20H23ClN4O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905103
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C21H23Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905106
N-(2-(2,4-dichlorophenyl)-3-((4-(2-methoxyacetyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C23H27Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905107
N-(2-(2,4-dichlorophenyl)-3-((5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C21H21Cl2N7O2S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905110
4-((2-(4-chlorophenyl)-6-cyclopropylimidazo[1,2-a]pyrazin-3-yl)methyl)morpholine
   Show/Hide
C20H21ClN4O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905187
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-(difluoromethyl)methanesulfonamide
   Show/Hide
C22H24ClF2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905381
N-(2-(2,4-dichlorophenyl)-3-((4-(4-fluorobenzoyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C27H26Cl2FN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905415
N-(2-(2,4-dichlorophenyl)-3-((4-(tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C25H29Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0905436
N-(2-(2,4-dichlorophenyl)-3-((4-(oxetane-3-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C24H27Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0906532
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-ethylmethanesulfonamide
   Show/Hide
C23H28ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0909196
N-(2-(2,4-dichlorophenyl)-3-((4-(pyridazine-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C25H25Cl2N7O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0909197
N-(2-(2,4-dichlorophenyl)-3-((6-oxohexahydropyrrolo[1,2-a]pyrazin-2(1H)-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C22H23Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0909236
N-(2-(2,4-dichlorophenyl)-3-((4-hydroxypiperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C19H21Cl2N5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0909495
4-((2-(4-chlorophenyl)-5-methyl-6-phenylimidazo[1,2-a]pyridin-3-yl)methyl)morpholine
   Show/Hide
C25H24ClN3O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911768
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)ethanesulfonamide
   Show/Hide
C22H26ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911769
N-(2-(2,4-dichlorophenyl)-3-((4-(2-hydroxyacetyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C22H25Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911770
1-(4-((2-(4-chlorophenyl)-6-(methylthio)imidazo[1,2-a]pyridin-3-yl)methyl)piperazin-1-yl)ethanone
   Show/Hide
C21H23ClN4OS
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911780
(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)(tetrahydro-2H-pyran-4-yl)methanone
   Show/Hide
C26H29Cl2N5O2
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911785
3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)-N,N-dimethylimidazo[1,2-a]pyridine-6-sulfonamide
   Show/Hide
C22H26ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911786
1-(4-((2-(4-chlorophenyl)-6-(methylsulfonyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperazin-1-yl)ethanone
   Show/Hide
C21H23ClN4O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0911787
1-(4-((2-(4-chlorophenyl)-6-(ethylsulfonyl)imidazo[1,2-a]pyridin-3-yl)methyl)piperazin-1-yl)ethanone
   Show/Hide
C22H25ClN4O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0913206
N-(2-(2,4-dichlorophenyl)-3-((4-(2-hydroxy-2-methylpropanoyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C23H27Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0913208
N-(2-(2,4-dichlorophenyl)-3-((4-(tetrahydro-2H-pyran-4-carbonyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)-N-methylmethanesulfonamide
   Show/Hide
C26H31Cl2N5O4S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0915220
3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)-N-methylimidazo[1,2-a]pyridine-6-sulfonamide
   Show/Hide
C21H24ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0924168
N-(2-(2,4-dichlorophenyl)-3-((4-(4-fluorobenzoyl)piperazin-1-yl)methyl)imidazo[1,2-a]pyridin-6-yl)methanesulfonamide
   Show/Hide
C26H24Cl2FN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0955619
N-(3-((4-acetylpiperazin-1-yl)methyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-6-yl)-N-isopropylmethanesulfonamide
   Show/Hide
C24H30ClN5O3S
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS
CP0958896
1-(4-((6-cyclopropyl-2-(2,4-dichlorophenyl)imidazo[1,2-a]pyrazin-3-yl)methyl)piperazin-1-yl)ethanone
   Show/Hide
C22H23Cl2N5O
 1
1
IC50 <= 1000 nM
   TI
   LI
   LO
   TS