Compound ID |
Compound Name |
Compound Formula |
CP0563721
|
3-[(1R,4S,7R,12R,15S,18S,21S,27S,30S,36S,39R,44R,47S,50S,53S,56S,59R,66S,69S,75S,80S,83S,86S)-4,36-bis(4-aminobutyl)-7-[[(2S)-1-[(2S)-2-[[(2S)-1-amino-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-methyl-1-oxobutan-2-yl]carbamoyl]-47-(2-amino-2-oxoethyl)-44-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-75-[(2S)-butan-2-yl]-15,53,56-tris(3-carbamimidamidopropyl)-66,80-bis(2-carboxyethyl)-18,86-bis(hydroxymethyl)-21,27,30,50,83-pentakis(2-methylpropyl)-2,5,13,16,19,22,25,28,31,34,37,45,48,51,54,57,65,68,71,74,77,78,81,84,87-pentacosaoxo-9,10,41,42,61,62-hexathia-3,6,14,17,20,23,26,29,32,35,38,46,49,52,55,58,64,67,70,73,76,79,82,85,88-pentacosazatricyclo[37.24.14.1112,59]octaoctacontan-69-yl]propanoic acid
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|
C146H238N44O41S6
|
1
|
1 |
EC50 = 0.024 nM
|
|
|
CP0952928
|
Apamin
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|
C79H131N31O24S4
|
1
|
1 |
EC50 = 0.027 nM
|
|
|
CP0965644
|
Scyllatoxin
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|
C142H236N44O40S7
|
1
|
1 |
EC50 = 0.29 nM
|
|
|
CP0495333
|
N-(5-chloro-2-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
2
|
1 |
EC50 = 91 nM
|
|
|
2 |
EC50 = 640 nM
|
|
|
CP0488487
|
N-(3-chloro-4-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
2
|
1 |
EC50 = 110 nM
|
|
|
2 |
EC50 = 990 nM
|
|
|
CP0488747
|
N-(2,5-difluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15F2N5
|
1
|
1 |
EC50 = 1890 nM
|
|
|
CP0568687
|
N-(4-chloro-2-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
1
|
1 |
EC50 = 1990 nM
|
|
|
CP0495334
|
N-(2-chloro-5-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15ClFN5
|
1
|
1 |
EC50 = 2970 nM
|
|
|
CP0571132
|
N-[3-chloro-4-(trifluoromethyl)phenyl]-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C17H15ClF3N5
|
1
|
1 |
EC50 = 3270 nM
|
|
|
CP0542557
|
2-(3,5-dimethylpyrazol-1-yl)-6-methyl-N-[4-(trifluoromethyl)phenyl]pyrimidin-4-amine
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|
C17H16F3N5
|
1
|
1 |
EC50 = 3450 nM
|
|
|
CP0577979
|
N-(3-chloro-4-fluorophenyl)-6-methyl-2-(2-methyl-1,3-oxazol-4-yl)pyrimidin-4-amine
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|
C15H12ClFN4O
|
1
|
1 |
EC50 = 3590 nM
|
|
|
CP0572066
|
N-(3-chloro-4-fluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)-4-methylpyridazin-3-amine
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|
C16H15ClFN5
|
1
|
1 |
EC50 = 4320 nM
|
|
|
CP0533728
|
N-(5-chloro-2-fluorophenyl)-6-methyl-2-(4-methylimidazol-1-yl)pyrimidin-4-amine
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|
C15H13ClFN5
|
1
|
1 |
EC50 = 4510 nM
|
|
|
CP0577977
|
N-(2,3-difluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H15F2N5
|
1
|
1 |
EC50 = 5030 nM
|
|
|
CP0579234
|
4-N-(3-chloro-4-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)pyrimidine-4,6-diamine
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|
C15H14ClFN6
|
1
|
1 |
EC50 = 6590 nM
|
|
|
CP0423346
|
N-cyclohexyl-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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|
C16H23N5
|
1
|
1 |
EC50 = 7480 nM
|
|
|
CP0543742
|
N-(5-chloro-2-fluorophenyl)-6-methyl-2-(2-methyl-1,3-oxazol-4-yl)pyrimidin-4-amine
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|
C15H12ClFN4O
|
1
|
1 |
EC50 = 13770 nM
|
|
|
CP0578211
|
3-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]-4-fluorobenzoic acid
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|
C17H16FN5O2
|
1
|
1 |
EC50 > 30000 nM
|
|
|
CP0577978
|
N-(3-chloro-4-fluorophenyl)-6-methyl-2-(4-methylimidazol-1-yl)pyrimidin-4-amine
Show/Hide
|
C15H13ClFN5
|
1
|
1 |
EC50 = 38810 nM
|
|
|
CP0542558
|
2-(3,5-dimethylpyrazol-1-yl)-N-(4-methoxycyclohexyl)-6-methylpyrimidin-4-amine
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|
C17H25N5O
|
1
|
1 |
EC50 = 49720 nM
|
|
|
CP0488486
|
4-N-(2-chloro-5-fluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H14ClFN6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0488746
|
(2S)-3-(4-cyanophenyl)-2-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]propanoic acid
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|
C20H20N6O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0534039
|
4-N-[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]cyclohexane-1,4-diamine
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|
C16H24N6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0543737
|
4-N-[3-chloro-4-(trifluoromethyl)phenyl]-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
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|
C16H14ClF3N6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0546040
|
4-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]cyclohexan-1-ol
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|
C16H23N5O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0546041
|
[4-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]cyclohexyl]methanol
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|
C17H25N5O
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0546042
|
(2S)-2-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]-3-(4-hydroxyphenyl)propanoic acid
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|
C19H21N5O3
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0568688
|
4-N-(4-chloro-2-fluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H14ClFN6
|
1
|
1 |
EC50 > 100000 nM
|
|
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CP0569645
|
N-[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]-5,6-dimethoxy-1H-benzimidazol-2-amine
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|
C19H21N7O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0569647
|
2-(3,5-dimethylpyrazol-1-yl)-6-methyl-N-(4-nitrophenyl)pyrimidin-4-amine
Show/Hide
|
C16H16N6O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0570039
|
(2S)-3-(3,4-difluorophenyl)-2-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]propanoic acid
Show/Hide
|
C19H19F2N5O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0570041
|
4-N-(2,5-difluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H14F2N6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0571131
|
2-(3,5-dimethylpyrazol-1-yl)-N-(4-fluorocyclohexyl)-6-methylpyrimidin-4-amine
Show/Hide
|
C16H22FN5
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0571133
|
4-N-(3-chlorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H15ClN6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0577976
|
4-[[2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-yl]amino]benzenethiol
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|
C16H17N5S
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0578210
|
N-[3-chloro-5-(trifluoromethyl)phenyl]-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
Show/Hide
|
C17H15ClF3N5
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0578212
|
4-N-(3-chloro-4-fluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H14ClFN6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0578286
|
2-(3,5-dimethylpyrazol-1-yl)-6-methyl-N-(4-nitrocyclohexyl)pyrimidin-4-amine
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|
C16H22N6O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0578287
|
2-(3,5-dimethylpyrazol-1-yl)-6-methyl-N-[2-(4-nitrophenyl)ethyl]pyrimidin-4-amine
Show/Hide
|
C18H20N6O2
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0578288
|
4-N-(5-chloro-2-fluorophenyl)-6-(3,5-dimethylpyrazol-1-yl)pyrimidine-2,4-diamine
Show/Hide
|
C15H14ClFN6
|
1
|
1 |
EC50 > 100000 nM
|
|
|
CP0867692
|
1,1'-(1,3-phenylenebis(methylene))bis(8-isopropyl-2-methylisoquinolinium)iodide
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|
C34H38I2N2
|
1
|
1 |
IC50 = 1600 nM
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