Brief Information of the Compound and Protein
Compound Name
N-(3-chloro-4-fluorophenyl)-2-(3,5-dimethylpyrazol-1-yl)-6-methylpyrimidin-4-amine
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PubChem ID
CID: 16800218
Canonical SMILES
Cc1cc(C)n(n1)-c1nc(C)cc(Nc2ccc(F)c(Cl)c2)n1
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Compound Formula C16H15ClFN5
Compound Structure
Protein Name
Small conductance calcium-activated potassium channel protein 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Calcium-activated potassium channel
Uniprot ID
P70604
Gene Name
KCNN2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
2
EC50 = 990 nM
   TI
   LI
   LO
   TS