Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05769 , Sodium channel protein type 7 subunit alpha
 Protein Info 
Gene Name SCN7A
Organism Homo sapiens, Human
Protein Classification Ion channel
Uniprot ID Q01118
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT05769
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0116756
 Compound Info 
US8952169, 64
   Show/Hide
C24H31FN2O4S
  3
1
IC50 = 0.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
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3
IC50 = 49 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527982
 Compound Info 
US9546164, 100
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C25H29Cl2FN2O4S
  3
1
IC50 = 0.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
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3
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0545193
 Compound Info 
US9546164, 209
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C26H31Cl2FN2O4S
  2
1
IC50 = 0.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 26 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0380512
 Compound Info 
US8952169, 148
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C24H30FNO4S
  2
1
IC50 = 1.1 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0481484
 Compound Info 
US8952169, 60
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C22H28FNO4S
  2
1
IC50 = 1.6 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 25 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0570697
 Compound Info 
US9546164, 99
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C25H29Cl2FN2O4S
  2
1
IC50 = 1.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0527984
 Compound Info 
US8952169, 154
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C25H33FN2O4S
  2
1
IC50 = 2.2 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 160 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0523309
 Compound Info 
US8952169, 155
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C25H33FN2O5S
  2
1
IC50 = 2.3 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 110 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0534976
 Compound Info 
US9546164, 139
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C24H27Cl2FN2O4S
  2
1
IC50 = 2.4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 120 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0543446
 Compound Info 
4-[(1-benzhydrylpiperidin-4-yl)methoxy]-5-cyclopropyl-2-fluoro-N-methylsulfonylbenzamide
   Show/Hide
C30H33FN2O4S
  2
1
IC50 = 3.6 nM
 Bioactivity Info 
   TI
   LI
   LO
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2
IC50 = 66 nM
 Bioactivity Info 
   TI
   LI
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   TS
CP0495226
 Compound Info 
4-(1-adamantylmethoxy)-5-cyclopropyl-2-fluoro-N-(oxetan-3-ylsulfonyl)benzamide
   Show/Hide
C24H30FNO5S
  2
1
IC50 = 4 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 38 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0463182
 Compound Info 
US8952169, 440
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C28H29FN2O4S
  2
1
IC50 = 5.5 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 23 nM
 Bioactivity Info 
   TI
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   TS
CP0550182
 Compound Info 
US9546164, 135
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C25H28F4N2O5S
  2
1
IC50 = 7.7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 31 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0533983
 Compound Info 
US9546164, 253
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C24H25Cl2FN2O5S
  2
1
IC50 = 9.8 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 34 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0559521
 Compound Info 
US9546164, 104
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C24H28ClFN2O4S
  2
1
IC50 = 22 nM
 Bioactivity Info 
   TI
   LI
   LO
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2
IC50 = 42 nM
 Bioactivity Info 
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CP0567644
 Compound Info 
N-[(3aS,4S,9S,10aS)-2,6-diamino-4-[(2,5-dioxopyrrolidin-1-yl)methyl]-10,10-dihydroxy-3a,4,8,9-tetrahydro-1H-pyrrolo[1,2-c]purin-9-yl]-5,6,7,8-tetrahydronaphthalene-1-carboxamide
   Show/Hide
C24H30N8O5
  1
1
IC50 = 72 nM
 Bioactivity Info 
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CP0532839
 Compound Info 
BDBM70996
   Show/Hide
C24H29FN2O4S
  2
1
IC50 = 140 nM
 Bioactivity Info 
   TI
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   TS
2
IC50 = 3200 nM
 Bioactivity Info 
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   LI
   LO
   TS
CP0543447
 Compound Info 
US9546164, 74
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C22H25FN2O4S
  2
1
IC50 = 1800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 25000 nM
 Bioactivity Info 
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   TS