Brief Information of the Compound and Protein
Compound Name
US9546164, 135
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PubChem ID
CID: 118110893
Canonical SMILES
CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCN(Cc3ccc(OC(F)(F)F)cc3)CC2)cc1F
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Compound Formula C25H28F4N2O5S
Compound Structure
Protein Name
Sodium channel protein type 7 subunit alpha
Protein Classification
Ion channel
>
Voltage-gated ion channel
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Voltage-gated sodium channel
Uniprot ID
Q01118
Gene Name
SCN7A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 7.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 31 nM
   TI
   LI
   LO
   TS