| Compound ID |
Compound Name |
Compound Formula |
|
CP0528880
|
(2S,3S)-3-[[2-methoxy-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methoxy]-2-phenylpiperidine
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|
C21H22F3N5O2
|
1
|
| 1 |
IC50 = 0.03 nM
|
|
|
|
CP0443583
|
(2S,3S)-3-[[2-methoxy-5-(5-methyltetrazol-1-yl)phenyl]methoxy]-2-phenylpiperidine
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|
C21H25N5O2
|
1
|
| 1 |
IC50 = 0.05 nM
|
|
|
|
CP0559365
|
(2S,3S)-3-[[2-methoxy-5-(tetrazol-1-yl)phenyl]methoxy]-2-phenylpiperidine
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|
C20H23N5O2
|
1
|
| 1 |
IC50 = 0.05 nM
|
|
|
|
CP0107813
|
3-[2-{1-[3,5-di(trifluoromethyl)phenyl]ethoxy}-3-(4-fluorophenyl)-1,4-oxazinan-4-ylmethyl]-4,5-dihydro-1H-1,2,4-triazol-5-one
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|
C23H21F7N4O3
|
1
|
| 1 |
IC50 = 0.09 nM
|
|
|
|
CP0463077
|
4-[3-[(1-ethyl-4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C29H29F3N2O
|
1
|
| 1 |
IC50 = 0.25 nM
|
|
|
|
CP0504467
|
4-[3-[(1-methyl-4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C28H27F3N2O
|
1
|
| 1 |
IC50 = 0.29 nM
|
|
|
|
CP0447811
|
2,6-difluoro-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H23F5N2O
|
1
|
| 1 |
IC50 = 0.32 nM
|
|
|
|
CP0463078
|
4-[3-[(4-phenyl-1-propan-2-ylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C30H31F3N2O
|
1
|
| 1 |
IC50 = 0.39 nM
|
|
|
|
CP0447810
|
4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H25F3N2O
|
1
|
| 1 |
IC50 = 0.45 nM
|
|
|
|
CP0463073
|
2,5-difluoro-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H23F5N2O
|
1
|
| 1 |
IC50 = 0.91 nM
|
|
|
|
CP0407872
|
4-[[3-(4-methoxyphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C27H28F3NO2
|
1
|
| 1 |
IC50 = 0.93 nM
|
|
|
|
CP0528874
|
2-fluoro-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H24F4N2O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0528875
|
2-chloro-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H24ClF3N2O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0443710
|
2-methyl-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C28H27F3N2O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0385768
|
4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]pyridine
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|
C25H25F3N2O
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0452645
|
4-[3-[(1-cyclopropyl-4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C30H29F3N2O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0559362
|
5-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]pyridine-2-carbonitrile
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|
C26H24F3N3O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0504468
|
4-[3-[(1-benzyl-4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C34H31F3N2O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0504472
|
4-[[3-(4-fluorophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C26H25F4NO
|
1
|
| 1 |
IC50 = 2.2 nM
|
|
|
|
CP0382160
|
4-[[3-(4-chlorophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C26H25ClF3NO
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0463080
|
4-[[3-(4-ethoxyphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C28H30F3NO2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0407870
|
4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]phenol
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|
C26H26F3NO2
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0504473
|
4-[[3-(4-nitrophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C26H25F3N2O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0547787
|
2,3,5,6-tetrafluoro-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
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|
C27H21F7N2O
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0443714
|
4-[[3-(3-fluorophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C26H25F4NO
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0443716
|
4-[[3-(3-nitrophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
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|
C26H25F3N2O3
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0550090
|
4-phenyl-4-[[3-phenyl-5-(trifluoromethyl)phenyl]methoxymethyl]piperidine
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|
C26H26F3NO
|
1
|
| 1 |
IC50 = 6.3 nM
|
|
|
|
CP0385763
|
4-[[3-(2-nitrophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C26H25F3N2O3
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0542712
|
4-[[3-(1,3-benzodioxol-5-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C27H26F3NO3
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0404467
|
6-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]pyridine-3-carbonitrile
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|
C26H24F3N3O
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0443719
|
4-[[3-(4-methylphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C27H28F3NO
|
1
|
| 1 |
IC50 = 8.4 nM
|
|
|
|
CP0504471
|
3-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]phenol
Show/Hide
|
C26H26F3NO2
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0463079
|
methyl 4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzoate
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|
C28H28F3NO3
|
1
|
| 1 |
IC50 = 17 nM
|
|
|
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CP0452647
|
N,N-dimethyl-4-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]aniline
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|
C28H31F3N2O
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0404469
|
4-[[3-(2-fluorophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C26H25F4NO
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0542708
|
4-[[3-(3-methylphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C27H28F3NO
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0504470
|
3-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]aniline
Show/Hide
|
C26H27F3N2O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0443718
|
4-phenyl-4-[[3-(trifluoromethyl)-5-[4-(trifluoromethyl)phenyl]phenyl]methoxymethyl]piperidine
Show/Hide
|
C27H25F6NO
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0528878
|
4-[[3-(2-methyltetrazol-5-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C22H24F3N5O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
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CP0528877
|
2-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]pyridine
Show/Hide
|
C25H25F3N2O
|
1
|
| 1 |
IC50 = 41 nM
|
|
|
|
CP0382162
|
4-[[3-(furan-2-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C24H24F3NO2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0559364
|
3-[3-[(4-phenylpiperidin-4-yl)methoxymethyl]-5-(trifluoromethyl)phenyl]benzonitrile
Show/Hide
|
C27H25F3N2O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0528876
|
4-[[3-(2-methoxyphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C27H28F3NO2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
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CP0443581
|
4-[[3-(1-methyltetrazol-5-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C22H24F3N5O
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0447812
|
4-[[3-(2-chlorophenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C26H25ClF3NO
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0882061
|
2-(3-(((4-phenylpiperidin-4-yl)methoxy)methyl)-5-(trifluoromethyl)phenyl)thiazole
Show/Hide
|
C23H23F3N2OS
|
1
|
| 1 |
IC50 = 70 nM
|
|
|
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CP0443582
|
4-[[2-methoxy-5-(5-methyltetrazol-1-yl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C22H27N5O2
|
1
|
| 1 |
IC50 = 87 nM
|
|
|
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CP0504469
|
4-[[3-naphthalen-2-yl-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C30H28F3NO
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
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CP0404470
|
4-[[3-(2-methylphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C27H28F3NO
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
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CP0463082
|
4-[[3-(5-methyltetrazol-1-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C22H24F3N5O
|
1
|
| 1 |
IC50 = 180 nM
|
|
|
|
CP0528879
|
4-phenyl-4-[[3-(2H-tetrazol-5-yl)-5-(trifluoromethyl)phenyl]methoxymethyl]piperidine
Show/Hide
|
C21H22F3N5O
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
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CP0404468
|
4-[[3-naphthalen-1-yl-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
Show/Hide
|
C30H28F3NO
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
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CP0382163
|
4-phenyl-4-[[3-(trifluoromethyl)-5-[5-(trifluoromethyl)tetrazol-1-yl]phenyl]methoxymethyl]piperidine
Show/Hide
|
C22H21F6N5O
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
