Brief Information of the Compound and Protein
Compound Name
4-[[3-(2-methylphenyl)-5-(trifluoromethyl)phenyl]methoxymethyl]-4-phenylpiperidine
    Show/Hide
PubChem ID
CID: 24783421
SID: 49707789
Canonical SMILES
Cc1ccccc1-c1cc(COCC2(CCNCC2)c2ccccc2)cc(c1)C(F)(F)F
    Show/Hide
Compound Formula C27H28F3NO
Compound Structure
Protein Name
Substance-P receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Neurokinin receptor
Uniprot ID
Q5DUB1
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS