Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
 Cell Line Info 
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05702 , Mas-related G-protein coupled receptor member X2
 Protein Info 
Gene Name MRGPRX2
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q96LB1
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006
 Cell Line Info 
 Protein ID: PT05702
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0574496
 Compound Info 
(2S)-2-[(3S)-4,4-difluoro-3-(1-oxidopyridin-1-ium-4-yl)piperidin-1-yl]-N-[5-(2,4-difluorophenoxy)pyrazin-2-yl]propanamide
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C23H21F4N5O3
  1
1
IC50 = 2.512 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0952804
 Compound Info 
2-((S)-3-(5-(aminomethyl)-6-oxo-1,6-dihydropyridin-3-yl)-4,4-difluoropiperidin-1-yl)-N-(5-phenoxypyridin-2-yl)propanamide
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C25H27F2N5O3
  1
1
IC50 <= 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0952805
 Compound Info 
2-(4,4-difluoro-3-(6-oxo-1,6-dihydropyridin-3-yl)cyclohexyl)-N-(5-(4-fluorophenoxy)pyridin-2-yl)propanamide
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C25H24F3N3O3
  1
1
IC50 <= 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0968144
 Compound Info 
N-(5-(4-chloro-6-fluoropyridin-3-yloxy)pyridin-2-yl)-2-((S)-4,4-difluoro-3-(6-oxo-1,6-dihydropyridin-3-yl)piperidin-1-yl)propanamide
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C23H21ClF3N5O3
  1
1
IC50 <= 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0968898
 Compound Info 
(S)-2-((S)-4,4-difluoro-3-(5-(methylsulfonylmethyl)-6-oxo-1,6-dihydropyridin-3-yl)piperidin-1-yl)-N-(5-(2,4-difluorophenoxy)pyridin-2-yl)propanamide
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C26H26F4N4O5S
  1
1
IC50 <= 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0970614
 Compound Info 
2-(4,4-difluoro-3-(5-((2-hydroxyethylamino)methyl)-6-oxo-1,6-dihydropyridin-3-yl)piperidin-1-yl)-N-(5-(4-fluorophenoxy)pyridin-2-yl)propanamide
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C27H30F3N5O4
  1
1
IC50 <= 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS