Brief Information of the Compound and Protein
Compound Name
(2S)-2-[(3S)-4,4-difluoro-3-(1-oxidopyridin-1-ium-4-yl)piperidin-1-yl]-N-[5-(2,4-difluorophenoxy)pyrazin-2-yl]propanamide
    Show/Hide
PubChem ID
CID: 164734529
Canonical SMILES
C[C@H](N1CCC(F)(F)[C@H](C1)c1cc[n+]([O-])cc1)C(=O)Nc1cnc(Oc2ccc(F)cc2F)cn1
    Show/Hide
Compound Formula C23H21F4N5O3
Compound Structure
Protein Name
Mas-related G-protein coupled receptor member X2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
Uniprot ID
Q96LB1
Gene Name
MRGPRX2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 2.512 nM
   TI
   LI
   LO
   TS