Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-2-((S)-4,4-difluoro-3-(5-(methylsulfonylmethyl)-6-oxo-1,6-dihydropyridin-3-yl)piperidin-1-yl)-N-(5-(2,4-difluorophenoxy)pyridin-2-yl)propanamide
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 PubChem ID
CID: 163238057
Canonical SMILES
C[C@@H](C(=O)Nc1ccc(Oc2ccc(F)cc2F)cn1)N1CCC(F)(F)[C@@H](c2c[nH]c(=O)c(CS(C)(=O)=O)c2)C1
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Compound Formula C26H26F4N4O5S
Compound Structure
Protein Name
 Protein Info 
Mas-related G-protein coupled receptor member X2
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
Uniprot ID
Q96LB1
Gene Name
MRGPRX2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 <= 10 nM
   TI
   LI
   LO
   TS