Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT05434 , P2Y purinoceptor 14
Gene Name P2RY14
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID Q15391
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT05434
 
Compound ID Compound Name Compound Formula
CP0868600
2-Thiouridine-5'-alpha,beta-methylene Diphosphate,bis-Triethylammonium Salt
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C16H31N3O10P2S
 1
1
EC50 = 0.92 nM
   TI
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CP0384686
((((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)methylphosphonic acid
   Show/Hide
C10H16N2O11P2
 1
1
EC50 = 11 nM
   TI
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CP0401576
[[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2-oxo-4-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] hydrogen phosphate
   Show/Hide
C15H24N2O16P2S
 1
1
EC50 = 11 nM
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CP0874897
Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(2-Thiouridine-5'-yl)ester, bis-Triethylammonium Salt
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C19H33N3O11P2S
 1
1
EC50 = 11 nM
   TI
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   TS
CP0858598
Diphosphoric Acid 1-beta-tert-Butyl Ester 2-(2-Thiouridine-5'-yl)ester, di Ammonium Salt
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C13H25N3O11P2S
 1
1
EC50 = 32 nM
   TI
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CP0917610
Diphosphoric Acid 1-beta-Ethyl Ester 2-(2-Thiouridine-5'-yl)-ester,di ammonium Salt
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C11H21N3O11P2S
 1
1
EC50 = 39 nM
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CP0918625
Diphosphoric Acid 1-beta-Propyl Ester 2-(2-Thiouridine-5'-yl)-ester, di ammonium Salt
   Show/Hide
C12H23N3O11P2S
 1
1
EC50 = 40 nM
   TI
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CP0901965
Diphosphoric Acid 1-beta-Methyl Ester 2-(2-Thiouridine-5'-yl)-ester, di ammonium Salt
   Show/Hide
C10H19N3O11P2S
 1
1
EC50 = 56 nM
   TI
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CP0439245
({[(2R,3S,4R,5R)-5-(2,4-Dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3,4-dihydroxy-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphoryl}-difluoro-methyl)-phosphonic acid
   Show/Hide
C10H14F2N2O11P2
 1
1
EC50 = 63 nM
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CP0864425
5-Iodouridine5'-Methylenediphosphate Triethylammonium salt
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C16H30IN3O11P2
 1
1
EC50 = 140 nM
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CP0398926
({[(2R,3S,4R,5R)-3,4-Dihydroxy-5-(5-iodo-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphoryl}-difluoro-methyl)-phosphonic acid
   Show/Hide
C10H13F2IN2O11P2
 1
1
EC50 = 142 nM
   TI
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CP0914501
Diphosphoric Acid 1-beta-Glycerol Ester 2-(Uridine-5'-yl)ester,bis-Triethylammonium Salt
   Show/Hide
C18H35N3O14P2
 1
1
EC50 = 167 nM
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CP0916086
Diphosphoric Acid 1-beta-tert-Butyl Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
   Show/Hide
C13H25N3O12P2
 1
1
EC50 = 252 nM
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CP0419133
4-Thio-UDP
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C9H14N2O11P2S
 1
1
EC50 = 320 nM
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CP0917612
Diphosphoric Acid 1-beta-(3-Butynyl)Ester 2-(Uridine-5'-yl)-ester, bis-Triethylammonium Salt
   Show/Hide
C19H33N3O12P2
 1
1
EC50 = 480 nM
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CP0916051
Diphosphoric Acid 1-beta-Phenyl Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
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C15H21N3O12P2
 1
1
EC50 = 768 nM
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CP0894017
Diphosphoric Acid 1-beta-(4-Nitrophenyl)Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
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C15H20N4O14P2
 1
1
EC50 = 1490 nM
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CP0914500
Diphosphoric Acid 1-r-Glycerol Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
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C12H23N3O14P2
 1
1
EC50 = 1600 nM
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CP0901964
Diphosphoric Acid 1-beta-(3-Chlorophenyl)Ester 2-(Uridine-5'-yl)ester, di ammonium Salt
   Show/Hide
C15H20ClN3O12P2
 1
1
EC50 = 1800 nM
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CP0888564
Diphosphoric Acid 1-beta-(4-Methoxyphenyl)Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
   Show/Hide
C16H23N3O13P2
 1
1
EC50 = 1900 nM
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CP0888563
Diphosphoric Acid 1-beta-Methyl Ester 2-(Uridine-5'-yl)ester, di ammonium Salt
   Show/Hide
C10H19N3O12P2
 1
1
EC50 = 2730 nM
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CP0844902
N4-Methoxycytidine 5'-Diphosphate triethylammonium Salt
   Show/Hide
C16H32N4O12P2
 1
1
EC50 = 3320 nM
   TI
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CP0874895
[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[(4E)-4-(methoxyimino)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid hydrochloride
   Show/Hide
C10H18ClN3O12P2
 1
1
EC50 = 3320 nM
   TI
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   TS
CP0914213
[({[(2R,3S,4R,5R)-3,4-dihydroxy-5-[4-(methoxyimino)-2-oxo-1,2,3,4-tetrahydropyrimidin-1-yl]oxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy]phosphonic acid
   Show/Hide
C16H31N3O11P2
 1
1
EC50 = 4580 nM
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CP0874914
Diphosphoric Acid 1-beta-Cyclohexyl Ester 2-(Uridine-5'-yl)ester,di ammonium Salt
   Show/Hide
C15H27N3O12P2
 1
1
EC50 = 5160 nM
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CP0918631
Diphosphoric Acid 1-beta-(2-Cyanoethyl)Ester 2-(Uridine-5'-yl)ester, di ammonium Salt
   Show/Hide
C12H20N4O12P2
 1
1
EC50 = 7460 nM
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CP0435758
3-[(4-methylbenzoyl)amino]-5-(4-piperidin-4-ylphenyl)benzoic acid
   Show/Hide
C26H26N2O3
 1
1
IC50 = 1.77 nM
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CP0569324
1-[(4-fluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
   Show/Hide
C19H16FN3O3
 1
1
IC50 = 1.93 nM
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CP0032210
4-(4-piperidin-4-ylphenyl)-7-[4-(trifluoromethyl)phenyl]naphthalene-2-carboxylic acid
   Show/Hide
C29H24F3NO2
 1
1
IC50 = 1.98 nM
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CP0546659
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(4-methoxyphenyl)acetamide
   Show/Hide
C22H18N2O3
 1
1
IC50 = 2 nM
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CP0551452
3-(furan-3-yl)-5-[(4-methylbenzoyl)amino]benzoic acid
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C19H15NO4
 1
1
IC50 = 2.18 nM
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CP0558094
3-[(4-methylbenzoyl)amino]-5-(1H-pyrazol-5-yl)benzoic acid
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C18H15N3O3
 1
1
IC50 = 2.63 nM
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CP0563460
3-(3,5-dimethyl-1,2-oxazol-4-yl)-5-[(4-methylbenzoyl)amino]benzoic acid
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C20H18N2O4
 1
1
IC50 = 2.95 nM
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CP0575592
5-[(4-acetylbenzoyl)amino]-1-[(4-fluorophenyl)methyl]pyrazole-3-carboxylic acid
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C20H16FN3O4
 1
1
IC50 = 3.81 nM
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CP0572909
5-[(4-methylbenzoyl)amino]-1-[[4-(trifluoromethyl)phenyl]methyl]pyrazole-3-carboxylic acid
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C20H16F3N3O3
 1
1
IC50 = 3.83 nM
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CP0547328
5-[(4-methylbenzoyl)amino]-1-[(3,4,5-trifluorophenyl)methyl]pyrazole-3-carboxylic acid
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C19H14F3N3O3
 1
1
IC50 = 4.01 nM
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CP0568085
1-[(3,4-difluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H15F2N3O3
 1
1
IC50 = 4.16 nM
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CP0580107
5-[(4-ethylbenzoyl)amino]-1-[(4-fluorophenyl)methyl]pyrazole-3-carboxylic acid
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C20H18FN3O3
 1
1
IC50 = 4.65 nM
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CP0547330
1-[(4-cyanophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C20H16N4O3
 1
1
IC50 = 4.66 nM
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CP0546985
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-[4-(trifluoromethoxy)phenyl]acetamide
   Show/Hide
C22H15F3N2O3
 1
1
IC50 = 4.8 nM
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CP0545529
5-[(4-methylbenzoyl)amino]-1-[[2-(trifluoromethyl)phenyl]methyl]pyrazole-3-carboxylic acid
   Show/Hide
C20H16F3N3O3
 1
1
IC50 = 4.83 nM
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CP0533864
3-[(4-methylbenzoyl)amino]-5-phenylbenzoic acid
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C21H17NO3
 1
1
IC50 = 4.85 nM
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CP0580196
5-[(4-methylbenzoyl)amino]-1-[(4-nitrophenyl)methyl]pyrazole-3-carboxylic acid
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C19H16N4O5
 1
1
IC50 = 5 nM
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CP0575967
1-[(3-fluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H16FN3O3
 1
1
IC50 = 5.39 nM
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CP0577362
1-[(3,5-dimethylphenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C21H21N3O3
 1
1
IC50 = 5.77 nM
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CP0546984
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamide
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C22H14ClF3N2O2
 1
1
IC50 = 6.1 nM
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CP0571384
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-(4-methylphenyl)acetamide
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C22H17ClN2O2
 1
1
IC50 = 6.7 nM
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CP0575995
1-[(4-chlorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H16ClN3O3
 1
1
IC50 = 7.11 nM
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CP0546657
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(4-methylphenyl)acetamide
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C22H18N2O2
 1
1
IC50 = 8.7 nM
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CP0545190
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-(4-methoxyphenyl)acetamide
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C22H17ClN2O3
 1
1
IC50 = 9.2 nM
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CP0578453
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(2-methylphenyl)acetamide
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C22H18N2O2
 1
1
IC50 = 9.3 nM
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CP0544882
N-[3-(5-chloro-1,3-benzoxazol-2-yl)-5-methylphenyl]-2-(3-methylphenyl)acetamide
   Show/Hide
C23H19ClN2O2
 1
1
IC50 = 9.7 nM
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CP0566510
3-[(4-methylbenzoyl)amino]-5-thiophen-3-ylbenzoic acid
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C19H15NO3S
 1
1
IC50 = 9.74 nM
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CP0546980
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-[4-(trifluoromethoxy)phenyl]acetamide
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C22H14ClF3N2O3
 1
1
IC50 = 9.8 nM
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CP0546982
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamide
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C22H15F3N2O2
 1
1
IC50 = 11.5 nM
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CP0567976
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(2-methoxyphenyl)acetamide
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C22H18N2O3
 1
1
IC50 = 12.2 nM
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CP0571385
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(4-butoxyphenyl)acetamide
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C25H24N2O3
 1
1
IC50 = 12.3 nM
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CP0544881
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-[3-(trifluoromethoxy)phenyl]acetamide
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C22H14ClF3N2O3
 1
1
IC50 = 12.6 nM
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CP0578454
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-(3-chlorophenyl)acetamide
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C21H14Cl2N2O2
 1
1
IC50 = 13.4 nM
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CP0576752
2-[1-[(4-fluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazol-3-yl]acetic acid
   Show/Hide
C20H18FN3O3
 1
1
IC50 = 14.26 nM
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CP0575968
5-[(4-methylbenzoyl)amino]-1-[[3-(trifluoromethyl)phenyl]methyl]pyrazole-3-carboxylic acid
   Show/Hide
C20H16F3N3O3
 1
1
IC50 = 15.7 nM
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CP0546661
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-[3-(trifluoromethoxy)phenyl]acetamide
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C22H15F3N2O3
 1
1
IC50 = 16.2 nM
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CP0546981
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-(2-methoxyphenyl)acetamide
   Show/Hide
C22H17ClN2O3
 1
1
IC50 = 17.1 nM
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CP0577724
N-[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-(4-methylphenyl)acetamide
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C23H20N2O2
 1
1
IC50 = 18.5 nM
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CP0577531
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(3-methylphenyl)acetamide
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C22H18N2O2
 1
1
IC50 = 21.8 nM
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CP0577757
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-(3-methoxyphenyl)acetamide
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C22H17ClN2O3
 1
1
IC50 = 23.8 nM
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CP0572726
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(3-methoxyphenyl)acetamide
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C22H18N2O3
 1
1
IC50 = 24.3 nM
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CP0550137
N-[3-(1,3-benzoxazol-2-yl)phenyl]-2-(3-bromophenyl)acetamide
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C21H15BrN2O2
 1
1
IC50 = 25.4 nM
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CP0547030
N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]-2-[3-(trifluoromethyl)phenyl]acetamide
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C22H14ClF3N2O2
 1
1
IC50 = 27.5 nM
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CP0546983
2-(2-bromophenyl)-N-[3-(5-chloro-1,3-benzoxazol-2-yl)phenyl]acetamide
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C21H14BrClN2O2
 1
1
IC50 = 32.9 nM
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CP0543240
N-[3-(5-methyl-1,3-benzoxazol-2-yl)phenyl]-2-[4-(trifluoromethyl)phenyl]acetamide
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C23H17F3N2O2
 1
1
IC50 = 35.1 nM
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CP0570113
1-[(3,5-difluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H15F2N3O3
 1
1
IC50 = 40.95 nM
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CP0544883
N-[4-(1-benzofuran-2-yl)phenyl]-2-(4-methylphenyl)acetamide
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C23H19NO2
 1
1
IC50 = 42.4 nM
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CP0579803
1-[(3-methoxyphenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C20H19N3O4
 1
1
IC50 = 61.22 nM
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CP0568773
1-[(4-acetylphenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C21H19N3O4
 1
1
IC50 = 67 nM
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CP0547331
1-(cyclopentylmethyl)-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C18H21N3O3
 1
1
IC50 = 99.65 nM
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CP0569319
1-[(2-fluorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H16FN3O3
 1
1
IC50 = 110.9 nM
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CP0567991
1-(cyclohexylmethyl)-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H23N3O3
 1
1
IC50 = 135.7 nM
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CP0564639
1-benzyl-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H17N3O3
 1
1
IC50 = 170.8 nM
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CP0545527
1-[(3-chlorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H16ClN3O3
 1
1
IC50 = 227.3 nM
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CP0578215
1-[(2-chlorophenyl)methyl]-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C19H16ClN3O3
 1
1
IC50 = 245.1 nM
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CP0573680
1-(cyclobutylmethyl)-5-[(4-methylbenzoyl)amino]pyrazole-3-carboxylic acid
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C17H19N3O3
 1
1
IC50 = 369 nM
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CP0580106
5-[(4-methylbenzoyl)amino]-1-[(2-methylphenyl)methyl]pyrazole-3-carboxylic acid
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C20H19N3O3
 1
1
IC50 = 531.5 nM
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