Compound ID |
Compound Name |
Compound Formula |
CP0453519
|
(3S)-N-[(2S)-6-amino-1-(2,2-diphenylethylamino)-1-oxohexan-2-yl]-2-(4-oxo-4-phenylbutanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide
Show/Hide
|
C40H44N4O4
|
2
|
1 |
EC50 = 630.96 nM
|
|
|
2 |
Ki = 39.81 nM
|
|
|
CP0880789
|
1-(2',3'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
2
|
1 |
EC50 = 630.96 nM
|
|
|
2 |
Ki = 398.11 nM
|
|
|
CP0896603
|
1-((1S,5R)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31I2N
|
2
|
1 |
EC50 = 630.96 nM
|
|
|
2 |
Ki = 50.12 nM
|
|
|
CP0856423
|
1-(2,2'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
2
|
1 |
EC50 = 794.33 nM
|
|
|
2 |
Ki = 199.53 nM
|
|
|
CP0857835
|
1-(2'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31BrIN
|
2
|
1 |
EC50 = 794.33 nM
|
|
|
2 |
Ki = 63.1 nM
|
|
|
CP0857839
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31I2N
|
2
|
1 |
EC50 = 1000 nM
|
|
|
2 |
Ki = 63.1 nM
|
|
|
CP0857828
|
1-((1S,2R,5S)-6,6-Dimethylbicyclo[3.1.1]heptan-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H33I2N
|
2
|
1 |
EC50 = 1258.93 nM
|
|
|
2 |
Ki = 100 nM
|
|
|
CP0866496
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((2'-methylbiphenyl-4-yl)methyl)methanaminium iodide
Show/Hide
|
C26H34IN
|
2
|
1 |
EC50 = 1258.93 nM
|
|
|
2 |
Ki = 158.49 nM
|
|
|
CP0877777
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-fluorobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31FIN
|
3
|
1 |
EC50 = 1258.93 nM
|
|
|
2 |
Ki = 501.19 nM
|
|
|
3 |
Ki = 630.96 nM
|
|
|
CP0857833
|
1-((1S,5R)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-3-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31I2N
|
2
|
1 |
EC50 = 1584.89 nM
|
|
|
2 |
Ki = 199.53 nM
|
|
|
CP0906868
|
1-(2'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
2
|
1 |
EC50 = 1584.89 nM
|
|
|
2 |
Ki = 100 nM
|
|
|
CP0896619
|
1-(2',6'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
2
|
1 |
EC50 = 1995.26 nM
|
|
|
2 |
Ki = 398.11 nM
|
|
|
CP0857838
|
1-(2',5'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
2
|
1 |
EC50 = 5011.87 nM
|
|
|
2 |
Ki = 251.19 nM
|
|
|
CP0856441
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2',6'-dimethylbiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C27H36IN
|
2
|
1 |
EC50 = 7943.28 nM
|
|
|
2 |
Ki = 1000 nM
|
|
|
CP0881021
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-methoxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C26H34INO
|
2
|
1 |
EC50 = 12589.25 nM
|
|
|
2 |
Ki = 158.49 nM
|
|
|
CP0081914
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl3N5O3
|
2
|
1 |
IC50 = 20 nM
|
|
|
2 |
IC50 = 60 nM
|
|
|
CP0516010
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-butyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C32H36Cl3N5O3
|
1
|
1 |
IC50 = 50 nM
|
|
|
CP0441530
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-isopropyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C31H34Cl3N5O3
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0476058
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl2FN5O3
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0516011
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-propyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C31H34Cl3N5O3
|
1
|
1 |
IC50 = 60 nM
|
|
|
CP0403451
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-benzamidophenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33Cl2N5O3
|
1
|
1 |
IC50 = 70 nM
|
|
|
CP0540285
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-cyanobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C31H32Cl2N6O3
|
1
|
1 |
IC50 = 80 nM
|
|
|
CP0442861
|
4-(4-((4-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33Cl2N5O3
|
1
|
1 |
IC50 = 120 nM
|
|
|
CP0540284
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophene-2-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C28H31Cl2N5O3S
|
1
|
1 |
IC50 = 130 nM
|
|
|
CP0403458
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-methoxybenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C31H35Cl2N5O4
|
1
|
1 |
IC50 = 170 nM
|
|
|
CP0403455
|
4-(4-((2-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33Cl2N5O3
|
1
|
1 |
IC50 = 190 nM
|
|
|
CP0403456
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(4-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl2FN5O3
|
1
|
1 |
IC50 = 200 nM
|
|
|
CP0442863
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,5-difluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H31Cl2F2N5O3
|
1
|
1 |
IC50 = 240 nM
|
|
|
CP0403453
|
4-(4-((4-chlorobenzyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C29H31Cl2N5O3
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0441533
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(isonicotinamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C29H32Cl2N6O3
|
1
|
1 |
IC50 = 250 nM
|
|
|
CP0442864
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,4-difluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H31Cl2F2N5O3
|
1
|
1 |
IC50 = 290 nM
|
|
|
CP0559648
|
4-(4-((3-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33Cl2N5O3
|
1
|
1 |
IC50 = 300 nM
|
|
|
CP0476056
|
4-(4-((4-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33ClFN5O3
|
1
|
1 |
IC50 = 320 nM
|
|
|
CP0390561
|
4-(4-((2-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33ClFN5O3
|
1
|
1 |
IC50 = 340 nM
|
|
|
CP0403454
|
4-(4-((3-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H33ClFN5O3
|
1
|
1 |
IC50 = 340 nM
|
|
|
CP0390560
|
4-(4-((3,4-dimethoxyphenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C32H38ClN5O5
|
1
|
1 |
IC50 = 420 nM
|
|
|
CP0436709
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophene-3-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C28H31Cl2N5O3S
|
1
|
1 |
IC50 = 490 nM
|
|
|
CP0441532
|
4-(2-(3-chlorobenzamido)-4-(phenethylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H34ClN5O3
|
1
|
1 |
IC50 = 510 nM
|
|
|
CP0515837
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl2FN5O3
|
1
|
1 |
IC50 = 590 nM
|
|
|
CP0476057
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(furan-2-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C28H31Cl2N5O4
|
1
|
1 |
IC50 = 640 nM
|
|
|
CP0409383
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl3N5O3
|
1
|
1 |
IC50 = 700 nM
|
|
|
CP0516009
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-methyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C29H30Cl3N5O3
|
1
|
1 |
IC50 = 800 nM
|
|
|
CP0403452
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N,N-dimethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C30H32Cl3N5O3
|
1
|
1 |
IC50 = 890 nM
|
|
|
CP0428398
|
N-[1-[3-(4-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
Show/Hide
|
C31H41N5O2
|
1
|
1 |
IC50 = 930 nM
|
|
|
CP0431061
|
4-(4-(benzylcarbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C29H32ClN5O3
|
1
|
1 |
IC50 = 1250 nM
|
|
|
CP0441531
|
4-(2-(3-chlorobenzamido)-4-((cyclopropylmethyl)carbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C26H32ClN5O3
|
1
|
1 |
IC50 = 2150 nM
|
|
|
CP0559647
|
4-(2-(3-chlorobenzamido)-4-(isopropylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C25H32ClN5O3
|
1
|
1 |
IC50 = 2160 nM
|
|
|
CP0496071
|
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
Show/Hide
|
C31H44N4O2
|
1
|
1 |
IC50 = 3100 nM
|
|
|
CP0436678
|
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(nicotinamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
Show/Hide
|
C29H32Cl2N6O3
|
1
|
1 |
IC50 = 3100 nM
|
|
|
CP0493413
|
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
Show/Hide
|
C30H41FN4O2
|
1
|
1 |
IC50 = 3200 nM
|
|
|
CP0391872
|
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-methoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
Show/Hide
|
C31H44N4O3
|
1
|
1 |
IC50 = 3300 nM
|
|
|
CP0408765
|
N-[1-[3-(3-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
Show/Hide
|
C31H41N5O2
|
1
|
1 |
IC50 = 5800 nM
|
|
|
CP0516008
|
methyl 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-1,4-diazepane-1-carboxylate
Show/Hide
|
C29H29Cl3N4O4
|
1
|
1 |
IC50 = 9800 nM
|
|
|
CP0399861
|
N-[1-[3-(2-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
Show/Hide
|
C31H41N5O2
|
1
|
1 |
IC50 = 10000 nM
|
|
|
CP0559646
|
ethyl 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-1,4-diazepane-1-carboxylate
Show/Hide
|
C30H31Cl3N4O4
|
1
|
1 |
IC50 = 13000 nM
|
|
|
CP0425371
|
N-[2-(dimethylamino)ethyl]-N-[1-(4-oxo-3-phenylquinazolin-2-yl)ethyl]decanamide
Show/Hide
|
C30H42N4O2
|
1
|
1 |
IC50 = 15000 nM
|
|
|
CP0399862
|
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-hydroxyphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
Show/Hide
|
C30H42N4O3
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0480335
|
N-[2-(dimethylamino)ethyl]-N-[1-[4-oxo-3-[4-(trifluoromethyl)phenyl]quinazolin-2-yl]ethyl]decanamide
Show/Hide
|
C31H41F3N4O2
|
1
|
1 |
IC50 > 100000 nM
|
|
|
CP0462976
|
(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(pyridin-3-ylmethyl)acetamide
Show/Hide
|
C32H27F4N5O3
|
1
|
1 |
Ki = 10 nM
|
|
|
CP0095851
|
(-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide
Show/Hide
|
C32H28F3N5O4
|
2
|
1 |
Ki = 39.81 nM
|
|
|
2 |
Ki = 158.49 nM
|
|
|
CP0852740
|
1-(3'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
3
|
1 |
Ki = 125.89 nM
|
|
|
2 |
Ki = 251.19 nM
|
|
|
3 |
Ki = 316.23 nM
|
|
|
CP0852404
|
N-(4-Chlorobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
Show/Hide
|
C19H27ClIN
|
2
|
1 |
Ki = 199.53 nM
|
|
|
2 |
Ki = 501.19 nM
|
|
|
CP0852818
|
1-(3'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31BrIN
|
1
|
1 |
Ki = 199.53 nM
|
|
|
CP0912318
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-(4-(thiophen-3-yl)benzyl)methanaminium iodide
Show/Hide
|
C23H30INS
|
2
|
1 |
Ki = 199.53 nM
|
|
|
2 |
Ki = 316.23 nM
|
|
|
CP0914967
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-nitrobiphenyl-4-yl)methyl)methanaminium iodide
Show/Hide
|
C25H31IN2O2
|
1
|
1 |
Ki = 199.53 nM
|
|
|
CP0914965
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-iodobenzyl)-N,Ndimethylmethanaminiumiodide
Show/Hide
|
C19H27I2N
|
2
|
1 |
Ki = 251.19 nM
|
|
|
2 |
Ki = 398.11 nM
|
|
|
CP0944416
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-(furan-3-yl)benzyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C23H30INO
|
1
|
1 |
Ki = 251.19 nM
|
|
|
CP0896623
|
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,5R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
1
|
1 |
Ki = 316.23 nM
|
|
|
CP0857834
|
1-(Biphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,Ndimethylmethanaminium iodide
Show/Hide
|
C25H32IN
|
2
|
1 |
Ki = 316.23 nM
|
|
|
2 |
Ki = 630.96 nM
|
|
|
CP0914968
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-fluorobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31FIN
|
1
|
1 |
Ki = 316.23 nM
|
|
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CP0917603
|
N-(4-Bromobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C19H27BrIN
|
1
|
1 |
Ki = 316.23 nM
|
|
|
CP0847110
|
N-((9H-Fluoren-2-yl)methyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
Show/Hide
|
C26H32IN
|
2
|
1 |
Ki = 398.11 nM
|
|
|
2 |
Ki = 501.19 nM
|
|
|
CP0891183
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-methylbiphenyl-4-yl)methyl)methanaminium iodide
Show/Hide
|
C26H34IN
|
1
|
1 |
Ki = 398.11 nM
|
|
|
CP0904237
|
N-(3,4-Dichlorobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C19H26Cl2IN
|
1
|
1 |
Ki = 398.11 nM
|
|
|
CP0914966
|
1-(3',5'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
1
|
1 |
Ki = 398.11 nM
|
|
|
CP0847111
|
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,5R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-3-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0880820
|
1-(2,3'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30Cl2IN
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0896602
|
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H33ClIN
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0908466
|
1-(4'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0908468
|
1-(3',4'-Dimethoxybiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C27H36INO2
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0917602
|
1-(Dibenzo[b,d]furan-2-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H30INO
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0934623
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-(trifluoromethyl)biphenyl-4-yl)methyl)methanaminium iodide
Show/Hide
|
C26H31F3IN
|
1
|
1 |
Ki = 501.19 nM
|
|
|
CP0871778
|
1-(2-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H31ClIN
|
1
|
1 |
Ki = 630.96 nM
|
|
|
CP0848969
|
1-(3'-Acetylbiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C27H34INO
|
1
|
1 |
Ki = 630.96 nM
|
|
|
CP0872332
|
N-(4-Iodobenzyl)-N,N-dimethyl-2-(1-adamantyl)ethanaminium iodide
Show/Hide
|
C21H31I2N
|
1
|
1 |
Ki = 630.96 nM
|
|
|
CP0881038
|
N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N-(4-iodobenzyl)-N-methylethanaminium iodide
Show/Hide
|
C20H29I2N
|
1
|
1 |
Ki = 630.96 nM
|
|
|
CP0852265
|
N-(4-Iodobenzyl)-N,N-dimethyl-2-adamantylmethanaminium iodide
Show/Hide
|
C20H29I2N
|
1
|
1 |
Ki = 794.33 nM
|
|
|
CP0852405
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-(methoxycarbonyl)biphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C27H34INO2
|
1
|
1 |
Ki = 1000 nM
|
|
|
CP0865307
|
2-(4-Chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylethanaminium iodide
Show/Hide
|
C20H29ClIN
|
1
|
1 |
Ki = 1000 nM
|
|
|
CP0904238
|
(E)-1-Cyclooctenyl-N-(4-iodobenzyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C18H27I2N
|
1
|
1 |
Ki = 1000 nM
|
|
|
CP0917418
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((9-methyl-9H-carbazol-2-yl)methyl)methanaminium iodide
Show/Hide
|
C26H33IN2
|
1
|
1 |
Ki = 1000 nM
|
|
|
CP0917604
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-fluorobenzyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C19H27FIN
|
1
|
1 |
Ki = 1258.93 nM
|
|
|
CP0944417
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)methanaminium iodide
Show/Hide
|
C26H31F3IN
|
1
|
1 |
Ki = 1258.93 nM
|
|
|
CP0885513
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(2-iodobenzyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C19H27I2N
|
1
|
1 |
Ki = 1584.89 nM
|
|
|
CP0885514
|
Endo/exo-N-(4-iodobenzyl)-N,N-dimethyl-1-((1S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)methanaminium iodide
Show/Hide
|
C20H31I2N
|
1
|
1 |
Ki = 1584.89 nM
|
|
|
CP0956182
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-hydroxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H32INO
|
1
|
1 |
Ki = 1584.89 nM
|
|
|
CP0862695
|
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-hydroxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H32INO
|
1
|
1 |
Ki = 1995.26 nM
|
|
|
CP0481343
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-(3-nitrophenyl)phenyl]methyl]methanamine
Show/Hide
|
C24H28N2O2
|
1
|
1 |
Ki = 1995.26 nM
|
|
|
CP0872333
|
N-(4-Iodobenzyl)-N,N-dimethyl-1-adamantylmethanaminium iodide
Show/Hide
|
C20H29I2N
|
1
|
1 |
Ki = 1995.26 nM
|
|
|
CP0908471
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-(4-phenoxybenzyl)methanaminium iodide
Show/Hide
|
C25H32INO
|
1
|
1 |
Ki = 1995.26 nM
|
|
|
CP0914970
|
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(3-iodobenzyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C19H27I2N
|
1
|
1 |
Ki = 1995.26 nM
|
|
|
CP0856424
|
N-Benzyl-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
Show/Hide
|
C19H28IN
|
2
|
1 |
Ki = 2511.89 nM
|
|
|
2 |
Ki = 3981.07 nM
|
|
|
CP0499404
|
1-(2-adamantyl)-N-[(4-iodophenyl)methyl]methanamine
Show/Hide
|
C18H24IN
|
1
|
1 |
Ki = 2511.89 nM
|
|
|
CP0522529
|
N-[(4-chlorophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C18H24ClN
|
1
|
1 |
Ki = 2511.89 nM
|
|
|
CP0544256
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(3-fluorophenyl)phenyl]methyl]-N-methylmethanamine
Show/Hide
|
C24H28FN
|
1
|
1 |
Ki = 2511.89 nM
|
|
|
CP0914969
|
2-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-2-methyl-1,2,3,4-tetrahydroisoquinolinium iodide
Show/Hide
|
C20H28IN
|
1
|
1 |
Ki = 2511.89 nM
|
|
|
CP0448252
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-phenylphenyl)methyl]methanamine
Show/Hide
|
C24H29N
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0470431
|
N-[(3,4-dichlorophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C18H23Cl2N
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0470433
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(4-iodophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C18H24IN
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0499966
|
N-[(4-bromophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C18H24BrN
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0912320
|
1-(3'-Aminobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H33IN2
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0944418
|
1-(Biphenyl-3-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
Show/Hide
|
C25H32IN
|
1
|
1 |
Ki = 3162.28 nM
|
|
|
CP0043434
|
2-(2-adamantyl)-1-(4-iodophenyl)guanidine
Show/Hide
|
C17H22IN3
|
1
|
1 |
Ki = 3981.07 nM
|
|
|
CP0474200
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-thiophen-3-ylphenyl)methyl]methanamine
Show/Hide
|
C22H27NS
|
1
|
1 |
Ki = 3981.07 nM
|
|
|
CP0481342
|
N-[[4-(3-chlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C24H28ClN
|
1
|
1 |
Ki = 3981.07 nM
|
|
|
CP0488173
|
N-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-N-[(4-iodophenyl)methyl]ethanamine
Show/Hide
|
C19H26IN
|
1
|
1 |
Ki = 3981.07 nM
|
|
|
CP0412829
|
2-(4-chlorophenyl)-N-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-N-methylethanamine
Show/Hide
|
C19H26ClN
|
1
|
1 |
Ki = 5011.87 nM
|
|
|
CP0493526
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(2-iodophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C18H24IN
|
1
|
1 |
Ki = 5011.87 nM
|
|
|
CP0554807
|
2-(1-adamantyl)-N-[(4-iodophenyl)methyl]-N-methylethanamine
Show/Hide
|
C20H28IN
|
1
|
1 |
Ki = 5011.87 nM
|
|
|
CP0381203
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(furan-3-yl)phenyl]methyl]-N-methylmethanamine
Show/Hide
|
C22H27NO
|
1
|
1 |
Ki = 6309.57 nM
|
|
|
CP0455513
|
3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]aniline
Show/Hide
|
C24H30N2
|
1
|
1 |
Ki = 6309.57 nM
|
|
|
CP0499967
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(4-fluorophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C18H24FN
|
1
|
1 |
Ki = 6309.57 nM
|
|
|
CP0488174
|
1-[(1E)-cycloocten-1-yl]-N-[(4-iodophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C17H24IN
|
1
|
1 |
Ki = 7943.28 nM
|
|
|
CP0493527
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(3-iodophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C18H24IN
|
1
|
1 |
Ki = 7943.28 nM
|
|
|
CP0493528
|
N-[(4-iodophenyl)methyl]-N-methyl-1-[(1S,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]methanamine
Show/Hide
|
C19H28IN
|
1
|
1 |
Ki = 7943.28 nM
|
|
|
CP0499403
|
1-(2-adamantyl)-N-[(4-iodophenyl)methyl]-N-methylmethanamine
Show/Hide
|
C19H26IN
|
1
|
1 |
Ki = 7943.28 nM
|
|
|
CP0412831
|
2-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-3,4-dihydro-1H-isoquinoline
Show/Hide
|
C19H25N
|
1
|
1 |
Ki = 12589.25 nM
|
|
|
CP0534103
|
N-benzyl-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C18H25N
|
1
|
1 |
Ki = 15848.93 nM
|
|
|
CP0412828
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(9-methylcarbazol-2-yl)methyl]methanamine
Show/Hide
|
C25H30N2
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0448251
|
N-(dibenzofuran-2-ylmethyl)-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C24H27NO
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0455514
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]methanamine
Show/Hide
|
C25H28F3N
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0474201
|
methyl 3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]benzoate
Show/Hide
|
C26H31NO2
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0481344
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-(3-methylphenyl)phenyl]methyl]methanamine
Show/Hide
|
C25H31N
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0481674
|
N-[[4-(4-chlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C24H28ClN
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0488170
|
N-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C26H33NO2
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0488171
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-(9H-fluoren-2-ylmethyl)-N-methylmethanamine
Show/Hide
|
C25H29N
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0493524
|
3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]phenol
Show/Hide
|
C24H29NO
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0493525
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(3-phenylphenyl)methyl]methanamine
Show/Hide
|
C24H29N
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0499402
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-phenoxyphenyl)methyl]methanamine
Show/Hide
|
C24H29NO
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0499964
|
1-[3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]phenyl]ethanone
Show/Hide
|
C26H31NO
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0499965
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(2-fluorophenyl)phenyl]methyl]-N-methylmethanamine
Show/Hide
|
C24H28FN
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0522528
|
N-[[4-(3,5-dichlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
Show/Hide
|
C24H27Cl2N
|
1
|
1 |
Ki > 316.23 nM
|
|
|
CP0544255
|
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]methanamine
Show/Hide
|
C25H28F3N
|
1
|
1 |
Ki > 316.23 nM
|
|
|