Brief Information of the Cell Line and Protein
Cell Line ID: CL000006 , HEK293
Synonyms
Hek293
HEK-293
HEK/293
HEK 293
HEK;293
293
293 HEK
293 Ad5
Graham 293
Graham-293
Human Embryonic Kidney 293
Category Transformed cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0045
Protein ID: PT03433 , C-X-C chemokine receptor type 3
Gene Name CXCR3
Organism Homo sapiens, Human
Protein Classification Membrane receptor
Uniprot ID P49682
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000006  Protein ID: PT03433
 
Compound ID Compound Name Compound Formula
CP0453519
(3S)-N-[(2S)-6-amino-1-(2,2-diphenylethylamino)-1-oxohexan-2-yl]-2-(4-oxo-4-phenylbutanoyl)-3,4-dihydro-1H-isoquinoline-3-carboxamide
   Show/Hide
C40H44N4O4
 2
1
EC50 = 630.96 nM
   TI
   LI
   LO
   TS
2
Ki = 39.81 nM
   TI
   LI
   LO
   TS
CP0880789
1-(2',3'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 2
1
EC50 = 630.96 nM
   TI
   LI
   LO
   TS
2
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0896603
1-((1S,5R)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31I2N
 2
1
EC50 = 630.96 nM
   TI
   LI
   LO
   TS
2
Ki = 50.12 nM
   TI
   LI
   LO
   TS
CP0856423
1-(2,2'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 2
1
EC50 = 794.33 nM
   TI
   LI
   LO
   TS
2
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0857835
1-(2'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31BrIN
 2
1
EC50 = 794.33 nM
   TI
   LI
   LO
   TS
2
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0857839
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31I2N
 2
1
EC50 = 1000 nM
   TI
   LI
   LO
   TS
2
Ki = 63.1 nM
   TI
   LI
   LO
   TS
CP0857828
1-((1S,2R,5S)-6,6-Dimethylbicyclo[3.1.1]heptan-2-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H33I2N
 2
1
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS
2
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0866496
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((2'-methylbiphenyl-4-yl)methyl)methanaminium iodide
   Show/Hide
C26H34IN
 2
1
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS
2
Ki = 158.49 nM
   TI
   LI
   LO
   TS
CP0877777
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-fluorobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31FIN
 3
1
EC50 = 1258.93 nM
   TI
   LI
   LO
   TS
2
Ki = 501.19 nM
   TI
   LI
   LO
   TS
3
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0857833
1-((1S,5R)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-3-yl)-N-((2'-iodobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31I2N
 2
1
EC50 = 1584.89 nM
   TI
   LI
   LO
   TS
2
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0906868
1-(2'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 2
1
EC50 = 1584.89 nM
   TI
   LI
   LO
   TS
2
Ki = 100 nM
   TI
   LI
   LO
   TS
CP0896619
1-(2',6'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 2
1
EC50 = 1995.26 nM
   TI
   LI
   LO
   TS
2
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0857838
1-(2',5'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 2
1
EC50 = 5011.87 nM
   TI
   LI
   LO
   TS
2
Ki = 251.19 nM
   TI
   LI
   LO
   TS
CP0856441
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2',6'-dimethylbiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C27H36IN
 2
1
EC50 = 7943.28 nM
   TI
   LI
   LO
   TS
2
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0881021
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-methoxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C26H34INO
 2
1
EC50 = 12589.25 nM
   TI
   LI
   LO
   TS
2
Ki = 158.49 nM
   TI
   LI
   LO
   TS
CP0081914
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl3N5O3
 2
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
2
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0516010
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-butyl-1,4-diazepane-1-carboxamide
   Show/Hide
C32H36Cl3N5O3
 1
1
IC50 = 50 nM
   TI
   LI
   LO
   TS
CP0441530
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-isopropyl-1,4-diazepane-1-carboxamide
   Show/Hide
C31H34Cl3N5O3
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0476058
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl2FN5O3
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0516011
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-propyl-1,4-diazepane-1-carboxamide
   Show/Hide
C31H34Cl3N5O3
 1
1
IC50 = 60 nM
   TI
   LI
   LO
   TS
CP0403451
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-benzamidophenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33Cl2N5O3
 1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
CP0540285
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-cyanobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C31H32Cl2N6O3
 1
1
IC50 = 80 nM
   TI
   LI
   LO
   TS
CP0442861
4-(4-((4-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33Cl2N5O3
 1
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
CP0540284
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophene-2-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C28H31Cl2N5O3S
 1
1
IC50 = 130 nM
   TI
   LI
   LO
   TS
CP0403458
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-methoxybenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C31H35Cl2N5O4
 1
1
IC50 = 170 nM
   TI
   LI
   LO
   TS
CP0403455
4-(4-((2-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33Cl2N5O3
 1
1
IC50 = 190 nM
   TI
   LI
   LO
   TS
CP0403456
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(4-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl2FN5O3
 1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CP0442863
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,5-difluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H31Cl2F2N5O3
 1
1
IC50 = 240 nM
   TI
   LI
   LO
   TS
CP0403453
4-(4-((4-chlorobenzyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C29H31Cl2N5O3
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0441533
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(isonicotinamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C29H32Cl2N6O3
 1
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
CP0442864
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3,4-difluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H31Cl2F2N5O3
 1
1
IC50 = 290 nM
   TI
   LI
   LO
   TS
CP0559648
4-(4-((3-chlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33Cl2N5O3
 1
1
IC50 = 300 nM
   TI
   LI
   LO
   TS
CP0476056
4-(4-((4-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33ClFN5O3
 1
1
IC50 = 320 nM
   TI
   LI
   LO
   TS
CP0390561
4-(4-((2-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33ClFN5O3
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0403454
4-(4-((3-fluorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H33ClFN5O3
 1
1
IC50 = 340 nM
   TI
   LI
   LO
   TS
CP0390560
4-(4-((3,4-dimethoxyphenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C32H38ClN5O5
 1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
CP0436709
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(thiophene-3-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C28H31Cl2N5O3S
 1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
CP0441532
4-(2-(3-chlorobenzamido)-4-(phenethylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H34ClN5O3
 1
1
IC50 = 510 nM
   TI
   LI
   LO
   TS
CP0515837
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-fluorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl2FN5O3
 1
1
IC50 = 590 nM
   TI
   LI
   LO
   TS
CP0476057
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(furan-2-carboxamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C28H31Cl2N5O4
 1
1
IC50 = 640 nM
   TI
   LI
   LO
   TS
CP0409383
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(2-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl3N5O3
 1
1
IC50 = 700 nM
   TI
   LI
   LO
   TS
CP0516009
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-methyl-1,4-diazepane-1-carboxamide
   Show/Hide
C29H30Cl3N5O3
 1
1
IC50 = 800 nM
   TI
   LI
   LO
   TS
CP0403452
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N,N-dimethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C30H32Cl3N5O3
 1
1
IC50 = 890 nM
   TI
   LI
   LO
   TS
CP0428398
N-[1-[3-(4-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
   Show/Hide
C31H41N5O2
 1
1
IC50 = 930 nM
   TI
   LI
   LO
   TS
CP0431061
4-(4-(benzylcarbamoyl)-2-(3-chlorobenzamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C29H32ClN5O3
 1
1
IC50 = 1250 nM
   TI
   LI
   LO
   TS
CP0441531
4-(2-(3-chlorobenzamido)-4-((cyclopropylmethyl)carbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C26H32ClN5O3
 1
1
IC50 = 2150 nM
   TI
   LI
   LO
   TS
CP0559647
4-(2-(3-chlorobenzamido)-4-(isopropylcarbamoyl)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C25H32ClN5O3
 1
1
IC50 = 2160 nM
   TI
   LI
   LO
   TS
CP0496071
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-methylphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
   Show/Hide
C31H44N4O2
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0436678
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(nicotinamido)phenyl)-N-ethyl-1,4-diazepane-1-carboxamide
   Show/Hide
C29H32Cl2N6O3
 1
1
IC50 = 3100 nM
   TI
   LI
   LO
   TS
CP0493413
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-fluorophenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
   Show/Hide
C30H41FN4O2
 1
1
IC50 = 3200 nM
   TI
   LI
   LO
   TS
CP0391872
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-methoxyphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
   Show/Hide
C31H44N4O3
 1
1
IC50 = 3300 nM
   TI
   LI
   LO
   TS
CP0408765
N-[1-[3-(3-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
   Show/Hide
C31H41N5O2
 1
1
IC50 = 5800 nM
   TI
   LI
   LO
   TS
CP0516008
methyl 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-1,4-diazepane-1-carboxylate
   Show/Hide
C29H29Cl3N4O4
 1
1
IC50 = 9800 nM
   TI
   LI
   LO
   TS
CP0399861
N-[1-[3-(2-cyanophenyl)-4-oxoquinazolin-2-yl]ethyl]-N-[2-(dimethylamino)ethyl]decanamide
   Show/Hide
C31H41N5O2
 1
1
IC50 = 10000 nM
   TI
   LI
   LO
   TS
CP0559646
ethyl 4-[2-[(3-chlorobenzoyl)amino]-4-[2-(2,4-dichlorophenyl)ethylcarbamoyl]phenyl]-1,4-diazepane-1-carboxylate
   Show/Hide
C30H31Cl3N4O4
 1
1
IC50 = 13000 nM
   TI
   LI
   LO
   TS
CP0425371
N-[2-(dimethylamino)ethyl]-N-[1-(4-oxo-3-phenylquinazolin-2-yl)ethyl]decanamide
   Show/Hide
C30H42N4O2
 1
1
IC50 = 15000 nM
   TI
   LI
   LO
   TS
CP0399862
N-[2-(dimethylamino)ethyl]-N-[1-[3-(4-hydroxyphenyl)-4-oxoquinazolin-2-yl]ethyl]decanamide
   Show/Hide
C30H42N4O3
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0480335
N-[2-(dimethylamino)ethyl]-N-[1-[4-oxo-3-[4-(trifluoromethyl)phenyl]quinazolin-2-yl]ethyl]decanamide
   Show/Hide
C31H41F3N4O2
 1
1
IC50 > 100000 nM
   TI
   LI
   LO
   TS
CP0462976
(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-2-(4-fluoro-3-(trifluoromethyl)phenyl)-N-(pyridin-3-ylmethyl)acetamide
   Show/Hide
C32H27F4N5O3
 1
1
Ki = 10 nM
   TI
   LI
   LO
   TS
CP0095851
(-)-(R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl)ethyl)-N-(pyridin-3-ylmethyl)-2-(4-(trifluoromethoxy)phenyl)acetamide
   Show/Hide
C32H28F3N5O4
 2
1
Ki = 39.81 nM
   TI
   LI
   LO
   TS
2
Ki = 158.49 nM
   TI
   LI
   LO
   TS
CP0852740
1-(3'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 3
1
Ki = 125.89 nM
   TI
   LI
   LO
   TS
2
Ki = 251.19 nM
   TI
   LI
   LO
   TS
3
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CP0852404
N-(4-Chlorobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
   Show/Hide
C19H27ClIN
 2
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
2
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0852818
1-(3'-Bromobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31BrIN
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0912318
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-(4-(thiophen-3-yl)benzyl)methanaminium iodide
   Show/Hide
C23H30INS
 2
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
2
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CP0914967
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-nitrobiphenyl-4-yl)methyl)methanaminium iodide
   Show/Hide
C25H31IN2O2
 1
1
Ki = 199.53 nM
   TI
   LI
   LO
   TS
CP0914965
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-iodobenzyl)-N,Ndimethylmethanaminiumiodide
   Show/Hide
C19H27I2N
 2
1
Ki = 251.19 nM
   TI
   LI
   LO
   TS
2
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0944416
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-(furan-3-yl)benzyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C23H30INO
 1
1
Ki = 251.19 nM
   TI
   LI
   LO
   TS
CP0896623
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,5R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CP0857834
1-(Biphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,Ndimethylmethanaminium iodide
   Show/Hide
C25H32IN
 2
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
2
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0914968
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-fluorobiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31FIN
 1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CP0917603
N-(4-Bromobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C19H27BrIN
 1
1
Ki = 316.23 nM
   TI
   LI
   LO
   TS
CP0847110
N-((9H-Fluoren-2-yl)methyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
   Show/Hide
C26H32IN
 2
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
2
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0891183
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-methylbiphenyl-4-yl)methyl)methanaminium iodide
   Show/Hide
C26H34IN
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0904237
N-(3,4-Dichlorobenzyl)-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C19H26Cl2IN
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0914966
1-(3',5'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 1
1
Ki = 398.11 nM
   TI
   LI
   LO
   TS
CP0847111
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,5R)-6,6-dimethylbicyclo[3.1.1]hept-2-en-3-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0880820
1-(2,3'-Dichlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30Cl2IN
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0896602
1-(3'-Chlorobiphenyl-4-yl)-N-(((1S,2R,5S)-6,6-dimethylbicyclo[3.1.1]heptan-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H33ClIN
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0908466
1-(4'-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0908468
1-(3',4'-Dimethoxybiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C27H36INO2
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0917602
1-(Dibenzo[b,d]furan-2-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H30INO
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0934623
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((3'-(trifluoromethyl)biphenyl-4-yl)methyl)methanaminium iodide
   Show/Hide
C26H31F3IN
 1
1
Ki = 501.19 nM
   TI
   LI
   LO
   TS
CP0871778
1-(2-Chlorobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H31ClIN
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0848969
1-(3'-Acetylbiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C27H34INO
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0872332
N-(4-Iodobenzyl)-N,N-dimethyl-2-(1-adamantyl)ethanaminium iodide
   Show/Hide
C21H31I2N
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0881038
N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N-(4-iodobenzyl)-N-methylethanaminium iodide
   Show/Hide
C20H29I2N
 1
1
Ki = 630.96 nM
   TI
   LI
   LO
   TS
CP0852265
N-(4-Iodobenzyl)-N,N-dimethyl-2-adamantylmethanaminium iodide
   Show/Hide
C20H29I2N
 1
1
Ki = 794.33 nM
   TI
   LI
   LO
   TS
CP0852405
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-(methoxycarbonyl)biphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C27H34INO2
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0865307
2-(4-Chlorophenyl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylethanaminium iodide
   Show/Hide
C20H29ClIN
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0904238
(E)-1-Cyclooctenyl-N-(4-iodobenzyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C18H27I2N
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0917418
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((9-methyl-9H-carbazol-2-yl)methyl)methanaminium iodide
   Show/Hide
C26H33IN2
 1
1
Ki = 1000 nM
   TI
   LI
   LO
   TS
CP0917604
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(4-fluorobenzyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C19H27FIN
 1
1
Ki = 1258.93 nM
   TI
   LI
   LO
   TS
CP0944417
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-((4'-(trifluoromethyl)biphenyl-4-yl)methyl)methanaminium iodide
   Show/Hide
C26H31F3IN
 1
1
Ki = 1258.93 nM
   TI
   LI
   LO
   TS
CP0885513
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(2-iodobenzyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C19H27I2N
 1
1
Ki = 1584.89 nM
   TI
   LI
   LO
   TS
CP0885514
Endo/exo-N-(4-iodobenzyl)-N,N-dimethyl-1-((1S,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl)methanaminium iodide
   Show/Hide
C20H31I2N
 1
1
Ki = 1584.89 nM
   TI
   LI
   LO
   TS
CP0956182
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((3'-hydroxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H32INO
 1
1
Ki = 1584.89 nM
   TI
   LI
   LO
   TS
CP0862695
1-((1R,5S)-6,6-Dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-((2'-hydroxybiphenyl-4-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H32INO
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0481343
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-(3-nitrophenyl)phenyl]methyl]methanamine
   Show/Hide
C24H28N2O2
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0872333
N-(4-Iodobenzyl)-N,N-dimethyl-1-adamantylmethanaminium iodide
   Show/Hide
C20H29I2N
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0908471
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,N-dimethyl-N-(4-phenoxybenzyl)methanaminium iodide
   Show/Hide
C25H32INO
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0914970
1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N-(3-iodobenzyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C19H27I2N
 1
1
Ki = 1995.26 nM
   TI
   LI
   LO
   TS
CP0856424
N-Benzyl-1-((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)-N,Ndimethylmethanaminium iodide
   Show/Hide
C19H28IN
 2
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
2
Ki = 3981.07 nM
   TI
   LI
   LO
   TS
CP0499404
1-(2-adamantyl)-N-[(4-iodophenyl)methyl]methanamine
   Show/Hide
C18H24IN
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0522529
N-[(4-chlorophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C18H24ClN
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0544256
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(3-fluorophenyl)phenyl]methyl]-N-methylmethanamine
   Show/Hide
C24H28FN
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0914969
2-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-2-methyl-1,2,3,4-tetrahydroisoquinolinium iodide
   Show/Hide
C20H28IN
 1
1
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
CP0448252
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-phenylphenyl)methyl]methanamine
   Show/Hide
C24H29N
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0470431
N-[(3,4-dichlorophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C18H23Cl2N
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0470433
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(4-iodophenyl)methyl]-N-methylmethanamine
   Show/Hide
C18H24IN
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0499966
N-[(4-bromophenyl)methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C18H24BrN
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0912320
1-(3'-Aminobiphenyl-4-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H33IN2
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0944418
1-(Biphenyl-3-yl)-N-(((1R,5S)-6,6-dimethylbicyclo[3.1.1]hept-2-en-2-yl)methyl)-N,N-dimethylmethanaminium iodide
   Show/Hide
C25H32IN
 1
1
Ki = 3162.28 nM
   TI
   LI
   LO
   TS
CP0043434
2-(2-adamantyl)-1-(4-iodophenyl)guanidine
   Show/Hide
C17H22IN3
 1
1
Ki = 3981.07 nM
   TI
   LI
   LO
   TS
CP0474200
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-thiophen-3-ylphenyl)methyl]methanamine
   Show/Hide
C22H27NS
 1
1
Ki = 3981.07 nM
   TI
   LI
   LO
   TS
CP0481342
N-[[4-(3-chlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C24H28ClN
 1
1
Ki = 3981.07 nM
   TI
   LI
   LO
   TS
CP0488173
N-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-N-[(4-iodophenyl)methyl]ethanamine
   Show/Hide
C19H26IN
 1
1
Ki = 3981.07 nM
   TI
   LI
   LO
   TS
CP0412829
2-(4-chlorophenyl)-N-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-N-methylethanamine
   Show/Hide
C19H26ClN
 1
1
Ki = 5011.87 nM
   TI
   LI
   LO
   TS
CP0493526
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(2-iodophenyl)methyl]-N-methylmethanamine
   Show/Hide
C18H24IN
 1
1
Ki = 5011.87 nM
   TI
   LI
   LO
   TS
CP0554807
2-(1-adamantyl)-N-[(4-iodophenyl)methyl]-N-methylethanamine
   Show/Hide
C20H28IN
 1
1
Ki = 5011.87 nM
   TI
   LI
   LO
   TS
CP0381203
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(furan-3-yl)phenyl]methyl]-N-methylmethanamine
   Show/Hide
C22H27NO
 1
1
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CP0455513
3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]aniline
   Show/Hide
C24H30N2
 1
1
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CP0499967
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(4-fluorophenyl)methyl]-N-methylmethanamine
   Show/Hide
C18H24FN
 1
1
Ki = 6309.57 nM
   TI
   LI
   LO
   TS
CP0488174
1-[(1E)-cycloocten-1-yl]-N-[(4-iodophenyl)methyl]-N-methylmethanamine
   Show/Hide
C17H24IN
 1
1
Ki = 7943.28 nM
   TI
   LI
   LO
   TS
CP0493527
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[(3-iodophenyl)methyl]-N-methylmethanamine
   Show/Hide
C18H24IN
 1
1
Ki = 7943.28 nM
   TI
   LI
   LO
   TS
CP0493528
N-[(4-iodophenyl)methyl]-N-methyl-1-[(1S,4R)-1,7,7-trimethyl-2-bicyclo[2.2.1]heptanyl]methanamine
   Show/Hide
C19H28IN
 1
1
Ki = 7943.28 nM
   TI
   LI
   LO
   TS
CP0499403
1-(2-adamantyl)-N-[(4-iodophenyl)methyl]-N-methylmethanamine
   Show/Hide
C19H26IN
 1
1
Ki = 7943.28 nM
   TI
   LI
   LO
   TS
CP0412831
2-[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl]-3,4-dihydro-1H-isoquinoline
   Show/Hide
C19H25N
 1
1
Ki = 12589.25 nM
   TI
   LI
   LO
   TS
CP0534103
N-benzyl-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C18H25N
 1
1
Ki = 15848.93 nM
   TI
   LI
   LO
   TS
CP0412828
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(9-methylcarbazol-2-yl)methyl]methanamine
   Show/Hide
C25H30N2
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0448251
N-(dibenzofuran-2-ylmethyl)-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C24H27NO
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0455514
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-[3-(trifluoromethyl)phenyl]phenyl]methyl]methanamine
   Show/Hide
C25H28F3N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0474201
methyl 3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]benzoate
   Show/Hide
C26H31NO2
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0481344
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-(3-methylphenyl)phenyl]methyl]methanamine
   Show/Hide
C25H31N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0481674
N-[[4-(4-chlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
   Show/Hide
C24H28ClN
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0488170
N-[[4-(3,4-dimethoxyphenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
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C26H33NO2
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0488171
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-(9H-fluoren-2-ylmethyl)-N-methylmethanamine
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C25H29N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0493524
3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]phenol
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C24H29NO
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0493525
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(3-phenylphenyl)methyl]methanamine
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C24H29N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0499402
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[(4-phenoxyphenyl)methyl]methanamine
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C24H29NO
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0499964
1-[3-[4-[[[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]methyl-methylamino]methyl]phenyl]phenyl]ethanone
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C26H31NO
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0499965
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-[[4-(2-fluorophenyl)phenyl]methyl]-N-methylmethanamine
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C24H28FN
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0522528
N-[[4-(3,5-dichlorophenyl)phenyl]methyl]-1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methylmethanamine
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C24H27Cl2N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS
CP0544255
1-[(1R,5S)-6,6-dimethyl-2-bicyclo[3.1.1]hept-2-enyl]-N-methyl-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]methanamine
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C25H28F3N
 1
1
Ki > 316.23 nM
   TI
   LI
   LO
   TS