General Information of the Compound
Compound ID
CP0441530
Compound Name
4-(4-((2,4-dichlorophenethyl)carbamoyl)-2-(3-chlorobenzamido)phenyl)-N-isopropyl-1,4-diazepane-1-carboxamide
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Structure
Formula
C31H34Cl3N5O3
Molecular Weight
631.004
Canonical SMILES
CC(C)NC(=O)N1CCCN(CC1)c1ccc(cc1NC(=O)c1cccc(Cl)c1)C(=O)NCCc1ccc(Cl)cc1Cl
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InChI
InChI=1S/C31H34Cl3N5O3/c1-20(2)36-31(42)39-14-4-13-38(15-16-39)28-10-8-23(18-27(28)37-30(41)22-5-3-6-24(32)17-22)29(40)35-12-11-21-7-9-25(33)19-26(21)34/h3,5-10,17-20H,4,11-16H2,1-2H3,(H,35,40)(H,36,42)(H,37,41)
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InChIKey
SZSOOVFYMGFERA-UHFFFAOYSA-N
Physicochemical Property
logP
6.5017
Rotatable Bonds
8
Heavy Atom Count
42
Polar Areas
93.78
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
4
Complexity
42

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 15604604
SID: 21961591
ChEMBL ID
CHEMBL199406
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03433, C-X-C chemokine receptor type 3
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 60 nM
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