| Compound ID |
Compound Name |
Compound Formula |
|
CP0431895
|
methyl 5-fluoro-3-(octylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylate
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|
C15H22FN3O5
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0053976
|
N-octyl-2,4-dioxo-5-(trifluoromethyl)pyrimidine-1-carboxamide
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|
C14H20F3N3O3
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0459988
|
methyl 5-fluoro-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylate
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|
C13H18FN3O5
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0149076
|
US10174015, Compound 9
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|
C15H18ClNO3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0190369
|
N-hexyl-2,4-dioxo-5-(trifluoromethyl)pyrimidine-1-carboxamide
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|
C12H16F3N3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0540732
|
ethyl 5-fluoro-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylate
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|
C14H20FN3O5
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0480434
|
5-fluoro-N-hexyl-3-methyl-2,4-dioxopyrimidine-1-carboxamide
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|
C12H18FN3O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0507607
|
2-methylpropyl 5-fluoro-3-(hexylcarbamoyl)-2,6-dioxopyrimidine-1-carboxylate
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|
C16H24FN3O5
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0431896
|
3-ethyl-5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C13H20FN3O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0433315
|
3-benzoyl-5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C18H20FN3O4
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0528645
|
5-fluoro-N-hexyl-3-(2-methylpropanoyl)-2,4-dioxopyrimidine-1-carboxamide
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|
C15H22FN3O4
|
1
|
| 1 |
IC50 = 21 nM
|
|
|
|
CP0043665
|
CARMOFUR
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|
C11H16FN3O3
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0158200
|
5-fluoro-N-octyl-2,4-dioxopyrimidine-1-carboxamide
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|
C13H20FN3O3
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0319988
|
5-bromo-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C11H16BrN3O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0484122
|
N-hexyl-3-methyl-2,4-dioxopyrimidine-1-carboxamide
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|
C12H19N3O3
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0522911
|
3-(cyclopropylmethyl)-5-fluoro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C15H22FN3O3
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0402448
|
US10174015, Compound 31
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|
C15H19NO4
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0322620
|
5-chloro-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C11H16ClN3O3
|
1
|
| 1 |
IC50 = 67 nM
|
|
|
|
CP0429797
|
3-(4-cyclohexyloxybenzoyl)-1,3-oxazolidin-2-one
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|
C16H19NO4
|
1
|
| 1 |
IC50 = 92 nM
|
|
|
|
CP0367234
|
N-hexyl-5-iodo-2,4-dioxopyrimidine-1-carboxamide
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|
C11H16IN3O3
|
1
|
| 1 |
IC50 = 147 nM
|
|
|
|
CP0322248
|
N-hexyl-2,4-dioxo-5-phenylpyrimidine-1-carboxamide
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|
C17H21N3O3
|
1
|
| 1 |
IC50 = 177 nM
|
|
|
|
CP0536468
|
US10174015, Compound 2
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|
C15H19NO3
|
1
|
| 1 |
IC50 = 270 nM
|
|
|
|
CP0528644
|
N-octyl-2,4-dioxopyrimidine-1-carboxamide
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|
C13H21N3O3
|
1
|
| 1 |
IC50 = 283 nM
|
|
|
|
CP0418827
|
N-heptyl-2,4-dioxopyrimidine-1-carboxamide
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|
C12H19N3O3
|
1
|
| 1 |
IC50 = 325 nM
|
|
|
|
CP0489888
|
N-hexyl-5-(hydroxymethyl)-2,4-dioxopyrimidine-1-carboxamide
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|
C12H19N3O4
|
1
|
| 1 |
IC50 = 417 nM
|
|
|
|
CP0317448
|
N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C11H17N3O3
|
1
|
| 1 |
IC50 = 426 nM
|
|
|
|
CP0511231
|
N-nonyl-2,4-dioxopyrimidine-1-carboxamide
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|
C14H23N3O3
|
1
|
| 1 |
IC50 = 464 nM
|
|
|
|
CP0522912
|
5-ethyl-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
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|
C13H21N3O3
|
1
|
| 1 |
IC50 = 733 nM
|
|
|
|
CP0250534
|
N-hexyl-5-morpholin-4-yl-2,4-dioxopyrimidine-1-carboxamide
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|
C15H24N4O4
|
1
|
| 1 |
IC50 = 875 nM
|
|
|
|
CP0322621
|
N-hexyl-5-methoxy-2,4-dioxopyrimidine-1-carboxamide
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|
C12H19N3O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0367235
|
N-hexyl-5-(4-methylpiperazin-1-yl)-2,4-dioxopyrimidine-1-carboxamide
Show/Hide
|
C16H27N5O3
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0540733
|
N-hexyl-5-methyl-2,4-dioxopyrimidine-1-carboxamide
Show/Hide
|
C12H19N3O3
|
1
|
| 1 |
IC50 = 1460 nM
|
|
|
|
CP0540731
|
2,4-dioxo-N-pentylpyrimidine-1-carboxamide
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|
C10H15N3O3
|
1
|
| 1 |
IC50 = 2100 nM
|
|
|
|
CP0322622
|
N-hexyl-5-(methylamino)-2,4-dioxopyrimidine-1-carboxamide
Show/Hide
|
C12H20N4O3
|
1
|
| 1 |
IC50 = 3400 nM
|
|
|
|
CP0480435
|
5-[benzyl(methyl)amino]-N-hexyl-2,4-dioxopyrimidine-1-carboxamide
Show/Hide
|
C19H26N4O3
|
1
|
| 1 |
IC50 = 5500 nM
|
|
|
|
CP0431964
|
N-butyl-2,4-dioxopyrimidine-1-carboxamide
Show/Hide
|
C9H13N3O3
|
1
|
| 1 |
IC50 = 8500 nM
|
|
|
