General Information of the Compound
Compound ID
CP0322622
Compound Name
N-hexyl-5-(methylamino)-2,4-dioxopyrimidine-1-carboxamide
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Structure
Formula
C12H20N4O3
Molecular Weight
268.317
Canonical SMILES
CCCCCCNC(=O)n1cc(NC)c(=O)[nH]c1=O
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InChI
InChI=1S/C12H20N4O3/c1-3-4-5-6-7-14-11(18)16-8-9(13-2)10(17)15-12(16)19/h8,13H,3-7H2,1-2H3,(H,14,18)(H,15,17,19)
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InChIKey
AKFJHMZDHFEJLR-UHFFFAOYSA-N
Physicochemical Property
logP
0.7163
Rotatable Bonds
6
Heavy Atom Count
19
Polar Areas
95.99
Hydrogen Bond Donor Count
3
Hydrogen Bond Acceptor Count
5
Complexity
19

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

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PubChem ID
CID: 71654964
ChEMBL ID
CHEMBL2333044
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03047, Acid ceramidase
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 3400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3400 nM