| Compound ID |
Compound Name |
Compound Formula |
|
CP0481948
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1-methylindazol-5-yl)acetamide
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
IC50 = 0.76 nM
|
|
|
|
CP0477388
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
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|
C20H20F2N4O
|
1
|
| 1 |
IC50 = 0.89 nM
|
|
|
|
CP0396376
|
N-[1-[(3,5-difluoro-4-methoxyphenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
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|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 0.92 nM
|
|
|
|
CP0396378
|
2-[4-(dimethylamino)phenyl]-N-[1-[[4-(trifluoromethoxy)phenyl]methyl]pyrazol-3-yl]acetamide
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|
C21H21F3N4O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0412187
|
N-[1-[(4-chlorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
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|
C20H21ClN4O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0412191
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(3-methyloxetan-3-yl)phenyl]acetamide
Show/Hide
|
C22H21F2N3O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0481954
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(3-fluorooxetan-3-yl)phenyl]acetamide
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|
C21H18F3N3O2
|
1
|
| 1 |
IC50 = 1.3 nM
|
|
|
|
CP0143412
|
2-(4-propan-2-ylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)pyridin-2-yl]ethyl]acetamide
Show/Hide
|
C20H23F3N2O2
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0408536
|
N-[2-(3,4-Difluoro-benzyl)-2H-[1,2,3]triazol-4-yl]-2-(1-methyl-1H-indazol-5-yl)-acetamide
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|
C19H16F2N6O
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0412186
|
N-[1-[[4-(difluoromethoxy)phenyl]methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H22F2N4O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0255833
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(2,2,2-trifluoroethoxy)phenyl]acetamide
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|
C21H18F3N5O2
|
1
|
| 1 |
IC50 = 1.7 nM
|
|
|
|
CP0392102
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(2,2-dimethyl-1,3-dioxolan-4-yl)phenyl]acetamide
Show/Hide
|
C23H23F2N3O3
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0408590
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1,3,3-trimethyl-2-oxoindol-5-yl)acetamide
Show/Hide
|
C23H22F2N4O2
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0412180
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H21F2N3O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0412200
|
N-[1-[(4-cyano-3-fluorophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
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|
C21H20FN5O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0477385
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-methylphenyl)methyl]pyrazol-3-yl]acetamide
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|
C21H24N4O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0520044
|
2-[4-(3,3-difluorocyclobutyl)phenyl]-N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H19F4N3O
|
1
|
| 1 |
IC50 = 1.8 nM
|
|
|
|
CP0389186
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1H-indol-6-yl)acetamide
Show/Hide
|
C20H16F2N4O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0366788
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(trifluoromethoxy)phenyl]acetamide
Show/Hide
|
C20H16F3N5O2
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0412179
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-fluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C20H21FN4O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0404249
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1H-indol-5-yl)acetamide
Show/Hide
|
C20H16F2N4O
|
1
|
| 1 |
IC50 = 2.1 nM
|
|
|
|
CP0412184
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(3,3-difluoropyrrolidin-1-yl)pyridin-3-yl]acetamide
Show/Hide
|
C21H19F4N5O
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0412178
|
2-(4-tert-butylphenyl)-N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H23N5O
|
1
|
| 1 |
IC50 = 2.6 nM
|
|
|
|
CP0446098
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(3-methyl-2-oxo-1,3-benzoxazol-6-yl)acetamide
Show/Hide
|
C20H16F2N4O3
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0446099
|
2-[4-(dimethylamino)phenyl]-N-[1-[(3-methylphenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C21H24N4O
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0396344
|
N-(1-benzylpyrazol-3-yl)-2-[4-(dimethylamino)phenyl]acetamide
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|
C20H22N4O
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0541307
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-ethyl-4-(2,2,2-trifluoroethoxy)phenyl]acetamide
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 2.9 nM
|
|
|
|
CP0412468
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(1-methylpyrrolo[2,3-b]pyridin-5-yl)acetamide
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
IC50 = 3.3 nM
|
|
|
|
CP0494493
|
2-(4-propan-2-ylphenyl)-N-[1-[2-(2,2,2-trifluoroethoxy)ethyl]pyrazol-3-yl]acetamide
Show/Hide
|
C18H22F3N3O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0865213
|
2-(4-Dimethylamino-phenyl)-N-[1-(4-methoxy-benzyl)-1H-pyrazol-3-yl]-acetamide
Show/Hide
|
C21H24N4O2
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0396345
|
N-[1-[(4-cyanophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C21H21N5O
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0396377
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-(oxetan-3-yloxy)phenyl]acetamide
Show/Hide
|
C21H19F2N3O3
|
1
|
| 1 |
IC50 = 3.6 nM
|
|
|
|
CP0382618
|
(3R,5S)-N-benzyl-1-[(2,3-difluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27F2N3O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0424410
|
(3R,5S)-1-benzyl-8-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0446022
|
(3R,5S)-N,1-dibenzyl-8-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0455950
|
(3R,5S)-1-[dideuterio(phenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H26N4O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0412195
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(dimethylamino)pyridin-3-yl]acetamide
Show/Hide
|
C19H19F2N5O
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0227177
|
N-[1-[(5-cyanopyridin-2-yl)methyl]pyrazol-3-yl]-2-[3-methyl-4-(3,3,3-trifluoropropoxy)phenyl]acetamide
Show/Hide
|
C22H20F3N5O2
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0481946
|
2-[4-(dimethylamino)phenyl]-N-[1-[(4-fluorophenyl)methyl]pyrazol-3-yl]propanamide
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|
C21H23FN4O
|
1
|
| 1 |
IC50 = 4.7 nM
|
|
|
|
CP0382629
|
(3R,5S)-1-[(2-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0396285
|
(3R,5S)-1-[(3-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 5 nM
|
|
|
|
CP0412188
|
N-[(6-pyrrolidin-1-ylpyridin-3-yl)methyl]-2-[[4-(trifluoromethoxy)phenyl]methyl]-1,3-oxazole-4-carboxamide
Show/Hide
|
C22H21F3N4O3
|
1
|
| 1 |
IC50 = 5.2 nM
|
|
|
|
CP0412194
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-[(3S)-3-fluoropyrrolidin-1-yl]pyridin-3-yl]acetamide
Show/Hide
|
C21H20F3N5O
|
1
|
| 1 |
IC50 = 5.4 nM
|
|
|
|
CP0377009
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H26F3N3O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0477602
|
(3R,5S)-1-benzyl-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C27H31N3O2
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0519621
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-2-(1,3-thiazol-5-yl)ethanone
Show/Hide
|
C23H25N3OS
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0519622
|
(3R,5S)-1-[(3,4-difluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H24F2N4O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0551482
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25F3N4OS
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0471804
|
2-[4-(3,3-difluorocyclobutyl)oxyphenyl]-N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C22H19F4N3O2
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0481945
|
N-(1-benzylpyrazol-3-yl)-2-(4-methoxy-3-methylphenyl)acetamide
Show/Hide
|
C20H21N3O2
|
1
|
| 1 |
IC50 = 6.5 nM
|
|
|
|
CP0404251
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[4-[(3-methyloxetan-3-yl)methoxy]phenyl]acetamide
Show/Hide
|
C23H23F2N3O3
|
1
|
| 1 |
IC50 = 6.6 nM
|
|
|
|
CP0382630
|
(3R,5S)-1-[(4-fluorophenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0532988
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-2-morpholin-4-ylethanone
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0471802
|
N-[4-[(3,4-difluorophenyl)methyl]-1,3-thiazol-2-yl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H20F2N2OS
|
1
|
| 1 |
IC50 = 7.1 nM
|
|
|
|
CP0085643
|
Act-709478
Show/Hide
|
C22H18F3N5O
|
1
|
| 1 |
IC50 = 7.5 nM
|
|
|
|
CP0481950
|
N-(1-benzylpyrazol-3-yl)-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0471801
|
2-(4-tert-butylphenyl)-N-[1-[(3,4-difluorophenyl)methyl]-1,2,4-triazol-3-yl]acetamide
Show/Hide
|
C21H22F2N4O
|
1
|
| 1 |
IC50 = 7.9 nM
|
|
|
|
CP0377011
|
(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0382620
|
(3R,5S)-1-benzyl-6,8-difluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H24F2N4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0444045
|
(3R,5S)-1-benzyl-7-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0446069
|
[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-(oxan-4-yl)methanone
Show/Hide
|
C24H30N2O2
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0412463
|
N-[[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]methyl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C22H23F2N3O
|
1
|
| 1 |
IC50 = 8 nM
|
|
|
|
CP0377008
|
[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-morpholin-4-ylmethanone
Show/Hide
|
C23H29N3O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0444047
|
(3R,5S)-N,1-dibenzyl-6-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
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CP0452703
|
(3R,5S)-3,5-dimethyl-N-pyridin-3-yl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H23F3N4O2
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
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CP0404250
|
N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-(3-methylbenzimidazol-5-yl)acetamide
Show/Hide
|
C20H17F2N5O
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0865116
|
4-(3,4-Difluorobenzyl)-N-(4-(dimethylamino)benzyl)thiazole-2-carboxamide
Show/Hide
|
C20H19F2N3OS
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
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CP0568717
|
N-[1-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]ethyl]-2-(4-propan-2-ylphenyl)acetamide
Show/Hide
|
C23H25F2N3O
|
1
|
| 1 |
IC50 = 9.8 nM
|
|
|
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CP0382579
|
(3R,5S)-N-benzyl-1-[(2-fluoropyridin-3-yl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H27FN4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0396294
|
(3R,5S)-N-benzyl-1-[(6-methoxypyridin-3-yl)methyl]-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H30N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0444018
|
(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C24H25FN4O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0444161
|
1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0532987
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C24H25F3N4O2
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
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CP0408544
|
1-[(3,4-difluorophenyl)methyl]-N-[[6-(3,3-difluoropyrrolidin-1-yl)pyridin-3-yl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H19F4N5O
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0486049
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4-[[2-[(4-fluorophenyl)methyl]-4H-imidazo[4,5-c]pyrazol-5-yl]methyl]-N,N-dimethylaniline
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C20H20FN5
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1
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| 1 |
IC50 = 10 nM
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CP0865123
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N-(4-Cyano-1-(3,4-difluorobenzyl)-1H-pyrazol-3-yl)-2-(1-methyl-1H-indazol-5-yl)acetamide
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C21H16F2N6O
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1
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| 1 |
IC50 = 10 nM
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CP0908753
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2-(6-Cyclopropyl-pyridin-3-yl)-N-[1-(3,4-difluoro-benzyl)-1H-pyrazol-3-yl]-acetamide
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C20H18F2N4O
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1
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| 1 |
IC50 = 10 nM
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CP0455946
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(3R,5S)-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1-[[5-(trifluoromethyl)furan-2-yl]methyl]-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
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C25H27F3N4O3
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1
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| 1 |
IC50 = 11 nM
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CP0477386
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N-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-2-[6-(2,2,2-trifluoroethoxy)pyridin-3-yl]acetamide
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C19H15F5N4O2
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1
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| 1 |
IC50 = 11 nM
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CP0444013
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(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C22H30N4O
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1
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| 1 |
IC50 = 12 nM
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CP0444064
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(3R,5S)-N-benzyl-3,5-dimethyl-1-[2-[(2-methylpropan-2-yl)oxy]ethyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C25H35N3O2
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1
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| 1 |
IC50 = 12 nM
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CP0444065
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(3R,5S)-1-benzyl-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
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C26H30N4O2
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1
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| 1 |
IC50 = 12 nM
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CP0452701
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(3R,5S)-1-benzyl-3,5-dimethyl-N-(oxetan-3-yl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C22H27N3O2
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1
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| 1 |
IC50 = 12 nM
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CP0382624
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(3R,5S)-N-benzyl-1-[(2,3-difluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
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C25H26F2N4O
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1
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| 1 |
IC50 = 13 nM
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CP0396289
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1-[(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
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C24H33N3O
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1
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| 1 |
IC50 = 13 nM
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CP0444157
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1-[(3R,5S)-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
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C24H25F3N4OS
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1
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| 1 |
IC50 = 13 nM
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CP0452712
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(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-(oxetan-3-yl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C22H26FN3O2
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1
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| 1 |
IC50 = 13 nM
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CP0382631
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(3R,5S)-1-(cyclopentylmethyl)-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C23H30N4O
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1
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| 1 |
IC50 = 14 nM
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CP0396286
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(3R,5S)-N-benzyl-3,5-dimethyl-1-[[6-(trifluoromethyl)pyridin-2-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C26H27F3N4O
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1
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| 1 |
IC50 = 14 nM
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CP0455947
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(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C24H26N4O
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1
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| 1 |
IC50 = 14 nM
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CP0482176
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2-[(3,4-difluorophenyl)methyl]-N-[(1-methylindazol-5-yl)methyl]triazole-4-carboxamide
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C19H16F2N6O
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1
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| 1 |
IC50 = 14 nM
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CP0377006
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(3R,5S)-N,1-dibenzyl-7-fluoro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
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C25H27FN4O
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1
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| 1 |
IC50 = 15 nM
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CP0870883
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(+/-)-N-Benzyl-3,5-dimethyl-1-(phenylmethyl-d2)-1,2,3,5-tetrahydro-4H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
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C25H28N4O
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1
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| 1 |
IC50 = 15 nM
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CP0429720
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N-(1-benzylpyrazol-3-yl)-2-[4-(trifluoromethoxy)phenyl]acetamide
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C19H16F3N3O2
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1
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| 1 |
IC50 = 15 nM
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CP0521801
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2-[(3,4-difluorophenyl)methyl]-N-[[4-(dimethylamino)phenyl]methyl]-1,3-thiazole-4-carboxamide
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C20H19F2N3OS
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1
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| 1 |
IC50 = 15 nM
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CP0396153
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(3R,5S)-1-benzyl-9-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C24H25FN4O
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1
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| 1 |
IC50 = 17 nM
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CP0408322
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1-[(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
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C26H28FN3O
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1
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| 1 |
IC50 = 17 nM
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CP0412183
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1-[(3,4-difluorophenyl)methyl]-N-[[4-(3-fluorooxetan-3-yl)phenyl]methyl]pyrazole-3-carboxamide
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C21H18F3N3O2
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1
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| 1 |
IC50 = 17 nM
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CP0412466
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N-(1-benzylpyrazol-3-yl)-2-(4-methylphenyl)acetamide
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C19H19N3O
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1
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| 1 |
IC50 = 18 nM
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CP0542970
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1-[(3R,5S)-6-fluoro-3,5-dimethyl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
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C24H24F4N4OS
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1
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| 1 |
IC50 = 20 nM
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CP0377005
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(3R,5S)-N,1-dibenzyl-8-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H27ClN4O
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1
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| 1 |
IC50 = 22 nM
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CP0389209
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1-[(3,4-difluorophenyl)methyl]-N-(1H-indol-5-ylmethyl)pyrazole-3-carboxamide
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C20H16F2N4O
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1
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| 1 |
IC50 = 22 nM
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CP0396296
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(3R,5S)-3,5-dimethyl-1-[2-[(2-methylpropan-2-yl)oxy]ethyl]-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C23H32N4O2
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1
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| 1 |
IC50 = 23 nM
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CP0486051
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N-(1-benzylpyrazol-3-yl)-2-(4-chlorophenyl)acetamide
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C18H16ClN3O
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1
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| 1 |
IC50 = 24 nM
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CP0377007
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(3R,5S)-N-[(4-methoxyphenyl)methyl]-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
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C24H34N4O2
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1
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| 1 |
IC50 = 25 nM
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CP0395729
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1-[(3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepin-4-yl]-3-(4-fluorophenyl)propan-1-one
Show/Hide
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C26H28FN3O
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1
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| 1 |
IC50 = 25 nM
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CP0486052
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N-(1-benzylpyrazol-3-yl)-2-(4-ethoxyphenyl)acetamide
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C20H21N3O2
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1
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| 1 |
IC50 = 25 nM
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CP0382615
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(3R)-N,1-dibenzyl-3-methyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C25H27N3O
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1
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| 1 |
IC50 = 26 nM
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CP0452705
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(3R,5S)-N-benzyl-1-[(2-fluorophenyl)methyl]-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H27FN4O
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1
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| 1 |
IC50 = 31 nM
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CP0482179
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N-(1-benzylpyrazol-3-yl)-2-(4-methoxyphenyl)acetamide
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C19H19N3O2
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1
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| 1 |
IC50 = 32 nM
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CP0396287
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(3R,5S)-3,5-dimethyl-N-pyridin-3-yl-1-[[2-(trifluoromethyl)-1,3-thiazol-5-yl]methyl]-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
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C22H22F3N5OS
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1
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| 1 |
IC50 = 33 nM
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CP0396291
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(3R,5S)-N,1-dibenzyl-3,5,8-trimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
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C26H30N4O
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1
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| 1 |
IC50 = 33 nM
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CP0412189
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1-[(3,4-difluorophenyl)methyl]-N-[(4-propan-2-ylphenyl)methyl]pyrazole-3-carboxamide
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C21H21F2N3O
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1
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| 1 |
IC50 = 40 nM
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CP0412202
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2-[4-(dimethylamino)phenyl]-N-[1-[(2-methylphenyl)methyl]pyrazol-3-yl]acetamide
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C21H24N4O
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1
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| 1 |
IC50 = 40 nM
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CP0444069
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(3R,5S)-N,1-dibenzyl-7-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H27ClN4O
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1
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| 1 |
IC50 = 46 nM
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CP0510168
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1-[(3R,5S)-6-fluoro-3,5-dimethyl-1-(3-methylbutyl)-3,5-dihydro-2H-1,4-benzodiazepin-4-yl]-3-pyridin-3-ylpropan-1-one
Show/Hide
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C24H32FN3O
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1
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| 1 |
IC50 = 52 nM
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CP0452704
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(3R,5S)-N,1-dibenzyl-7-chloro-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H27ClN4O
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1
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| 1 |
IC50 = 55 nM
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CP0482178
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N-(1-benzylpyrazol-3-yl)-2-(3-chlorophenyl)acetamide
Show/Hide
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C18H16ClN3O
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1
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| 1 |
IC50 = 64 nM
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CP0865121
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N-(1-Benzyl-1H-pyrazol-3-yl)-2-m-tolyl-acetamide
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C19H19N3O
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1
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| 1 |
IC50 = 67 nM
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CP0382622
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(3R,5S)-1-benzyl-8-fluoro-7-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H27FN4O2
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1
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| 1 |
IC50 = 73 nM
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CP0396298
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(3R,5S)-1-benzyl-3,5,8-trimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 74 nM
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CP0410031
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N-[[1-[2-(tert-butylamino)-2-oxoethyl]piperidin-4-yl]methyl]-3-chloro-5-fluorobenzamide
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C19H27ClFN3O2
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1
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| 1 |
IC50 = 86 nM
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CP0382582
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(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,2-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 91 nM
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CP0396284
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(3S,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C26H29N3O
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1
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| 1 |
IC50 = 95 nM
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CP0455948
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(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-3-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 95 nM
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CP0446023
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(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-2-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 97 nM
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CP0382581
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(3R,5S)-1-benzyl-7-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O2
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1
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| 1 |
IC50 = 100 nM
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CP0429388
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4-bromo-5-cyclopropyl-1-(2-fluorophenyl)-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
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C22H18BrF4N3O2
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1
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| 1 |
IC50 = 110 nM
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CP0471814
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N-(1-benzylpyrazol-3-yl)-2-(2-methylphenyl)acetamide
Show/Hide
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C19H19N3O
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1
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| 1 |
IC50 = 120 nM
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CP0382580
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(3R,5S)-1-benzyl-6-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O2
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1
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| 1 |
IC50 = 130 nM
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CP0424412
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(3R,5S)-1-benzyl-6-fluoro-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C23H24FN5O
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1
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| 1 |
IC50 = 133 nM
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CP0446025
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(3R,5S)-1-benzyl-8-bromo-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C24H25BrN4O
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1
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| 1 |
IC50 = 137 nM
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CP0396295
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(3R,5S)-N-benzyl-1-ethyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C21H27N3O
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1
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| 1 |
IC50 = 139 nM
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CP0446027
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(3R,5S)-1-[dideuterio(phenyl)methyl]-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C23H25N5O
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1
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| 1 |
IC50 = 148 nM
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CP0444160
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(5S)-N,1-dibenzyl-5-methyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H27N3O
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1
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| 1 |
IC50 = 164 nM
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CP0519502
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(5S,7R)-N,9-dibenzyl-5,7-dimethyl-7,8-dihydro-5H-pyridazino[3,4-e][1,4]diazepine-6-carboxamide
Show/Hide
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C24H27N5O
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1
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| 1 |
IC50 = 206 nM
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CP0519761
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(3R,5S)-1-benzyl-3,5-dimethyl-4-(1-methylimidazol-4-yl)sulfonyl-3,5-dihydro-2H-1,4-benzodiazepine
Show/Hide
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C22H26N4O2S
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1
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| 1 |
IC50 = 210 nM
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CP0382626
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N,1-dibenzyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C24H25N3O
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1
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| 1 |
IC50 = 214 nM
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CP0396297
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(3R,5S)-N-benzyl-3,5-dimethyl-1-phenyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H27N3O
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1
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| 1 |
IC50 = 225 nM
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CP0475698
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(3R,5S)-3,5-dimethyl-1-(oxan-2-ylmethyl)-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C23H30N4O2
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1
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| 1 |
IC50 = 243 nM
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CP0444163
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(3R,5S)-3,5-dimethyl-1-(3-methylbutyl)-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C21H29N5O
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1
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| 1 |
IC50 = 251 nM
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CP0382627
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(3R,5S)-N,1-dibenzyl-3,5-dimethyl-2-oxo-3,5-dihydro-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C26H27N3O2
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1
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| 1 |
IC50 = 259 nM
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CP0471781
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3-chloro-2-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5-(trifluoromethyl)-4,5,6,7-tetrahydroisoindole-1-carboxamide
Show/Hide
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C22H26ClF3N2O2
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1
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| 1 |
IC50 = 270 nM
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CP0396292
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(3R,5S)-N,1-dibenzyl-3,5-dimethyl-8-(trifluoromethyl)-3,5-dihydro-2H-pyrido[2,3-e][1,4]diazepine-4-carboxamide
Show/Hide
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C26H27F3N4O
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1
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| 1 |
IC50 = 281 nM
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CP0477601
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(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
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C23H25N5O
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1
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| 1 |
IC50 = 306 nM
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CP0396288
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(3R,5S)-1-benzyl-8-cyano-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H25N5O
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1
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| 1 |
IC50 = 308 nM
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CP0470836
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3-chloro-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H23ClF3N3O2
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1
|
| 1 |
IC50 = 320 nM
|
|
|
|
CP0396283
|
(2R,5S)-N,1-dibenzyl-2,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 326 nM
|
|
|
|
CP0059960
|
N,3-bis(4-fluorophenyl)-5-pyridin-4-yl-3,4-dihydropyrazole-2-carboxamide
Show/Hide
|
C21H16F2N4O
|
1
|
| 1 |
IC50 = 340 nM
|
|
|
|
CP0429371
|
3-bromo-N-[[4-(methoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0471736
|
3-chloro-N-[(2-ethoxyphenyl)methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H27ClN2O2
|
1
|
| 1 |
IC50 = 370 nM
|
|
|
|
CP0475586
|
(5S,6S)-3-chloro-2,5,6-trimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-4,5,6,7-tetrahydroisoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0486053
|
N-(1-benzylpyrazol-3-yl)-2-phenylacetamide
Show/Hide
|
C18H17N3O
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0481947
|
3-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-5-[(4-propan-2-ylphenyl)methyl]-1H-1,2,4-triazole
Show/Hide
|
C22H21F2N5
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0475587
|
3-chloro-2-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5,6-dihydro-4H-cyclopenta[c]pyrrole-1-carboxamide
Show/Hide
|
C20H25ClN2O2
|
1
|
| 1 |
IC50 = 460 nM
|
|
|
|
CP0382617
|
benzyl (3R,5S)-1-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxylate
Show/Hide
|
C26H28N2O2
|
1
|
| 1 |
IC50 = 473 nM
|
|
|
|
CP0412197
|
2-[4-(dimethylamino)phenyl]-N-[1-[[4-(2-oxopyrrolidin-1-yl)phenyl]methyl]pyrazol-3-yl]acetamide
Show/Hide
|
C24H27N5O2
|
1
|
| 1 |
IC50 = 520 nM
|
|
|
|
CP0475589
|
3-bromo-N-[[2-(ethoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C21H26BrNO2S
|
1
|
| 1 |
IC50 = 540 nM
|
|
|
|
CP0408320
|
(3R,5S)-1-benzyl-8-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O2
|
1
|
| 1 |
IC50 = 610 nM
|
|
|
|
CP0475592
|
(2R,4S)-N-[[4-(ethoxymethyl)phenyl]methyl]-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C22H27NO2S
|
1
|
| 1 |
IC50 = 620 nM
|
|
|
|
CP0396293
|
(3S,5R)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 641 nM
|
|
|
|
CP0396364
|
4-(2-hydroxyethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C27H24F3N3O3
|
1
|
| 1 |
IC50 = 650 nM
|
|
|
|
CP0396309
|
3-chloro-N-[[2-(ethoxymethyl)phenyl]methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H29ClN2O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0482595
|
3-chloro-2,6,6-trimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-5,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0520052
|
5-chloro-4-ethyl-1,3-dimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
|
C20H27ClN2O2
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0536135
|
3-chloro-2,5,5-trimethyl-N-[[2-(pyrazol-1-ylmethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H27ClN4O
|
1
|
| 1 |
IC50 = 710 nM
|
|
|
|
CP0085972
|
3-chloro-2,5,5-trimethyl-N-[[2-(propan-2-yloxymethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C23H31ClN2O2
|
1
|
| 1 |
IC50 = 740 nM
|
|
|
|
CP0450852
|
5-chloro-3-ethyl-1,4-dimethyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
|
C20H27ClN2O2
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0475588
|
3-bromo-N-[[2-(methoxymethyl)phenyl]methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
|
CP0429392
|
4-(difluoromethyl)-1-methyl-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H18F5N3O2
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0389183
|
tert-butyl 3-chloro-2-methyl-1-[[2-(2-methylpropoxy)phenyl]methylcarbamoyl]-4,6-dihydropyrrolo[3,4-c]pyrrole-5-carboxylate
Show/Hide
|
C24H32ClN3O4
|
1
|
| 1 |
IC50 = 890 nM
|
|
|
|
CP0446070
|
(3R,5S)-N,1-dibenzyl-N,3,5-trimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C27H31N3O
|
1
|
| 1 |
IC50 = 892 nM
|
|
|
|
CP0463422
|
4-[2-(cyclopropylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C30H29F3N4O2
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
|
CP0470835
|
3-chloro-2,5,5-trimethyl-N-[[5-methyl-4-(pyrazol-1-ylmethyl)-1,2-oxazol-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H26ClN5O2
|
1
|
| 1 |
IC50 = 910 nM
|
|
|
|
CP0471738
|
3-chloro-2,5,5-trimethyl-N-[[2-(1,2,4-triazol-1-ylmethyl)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C22H26ClN5O
|
1
|
| 1 |
IC50 = 940 nM
|
|
|
|
CP0429373
|
3-cyano-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H23F3N4O2
|
1
|
| 1 |
IC50 = 980 nM
|
|
|
|
CP0534094
|
(7R,9S)-N,5-dibenzyl-7,9-dimethyl-7,9-dihydro-6H-pyrimido[5,4-e][1,4]diazepine-8-carboxamide
Show/Hide
|
C24H27N5O
|
1
|
| 1 |
IC50 = 1000 nM
|
|
|
|
CP0382616
|
(2S,5S)-N,1-dibenzyl-2,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 1003 nM
|
|
|
|
CP0486197
|
(2R,4S)-3,3,9-trimethyl-N-[[2-(trifluoromethyl)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NOS
|
1
|
| 1 |
IC50 = 1060 nM
|
|
|
|
CP0471735
|
(2R,4S)-3,3,9-trimethyl-N-[[3-(trifluoromethyl)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NOS
|
1
|
| 1 |
IC50 = 1150 nM
|
|
|
|
CP0408589
|
4-(hydroxymethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H22F3N3O3
|
1
|
| 1 |
IC50 = 1370 nM
|
|
|
|
CP0389184
|
4-(difluoromethyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-(2,2,2-trifluoroethyl)pyrazole-3-carboxamide
Show/Hide
|
C22H17F8N3O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0450864
|
4-bromo-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-1-(2,2,2-trifluoroethyl)pyrazole-3-carboxamide
Show/Hide
|
C21H16BrF6N3O2
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0408539
|
(2R,4S)-3,3,9-trimethyl-N-[(2-methylphenyl)methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
IC50 = 1500 nM
|
|
|
|
CP0382628
|
(3R)-1-benzyl-3-methyl-4-(2-phenylethyl)-2,3-dihydro-1,4-benzodiazepin-5-one
Show/Hide
|
C25H26N2O
|
1
|
| 1 |
IC50 = 1589 nM
|
|
|
|
CP0536131
|
(2R,4S)-3,3,9-trimethyl-N-[[3-(trifluoromethoxy)phenyl]methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H20F3NO2S
|
1
|
| 1 |
IC50 = 1640 nM
|
|
|
|
CP0486214
|
(2R,4S)-N-[(2-chlorophenyl)methyl]-3,3,9-trimethyl-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C19H20ClNOS
|
1
|
| 1 |
IC50 = 1660 nM
|
|
|
|
CP0408588
|
4-bromo-5-ethyl-1-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C21H19BrF3N3O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0483098
|
N-(1-benzylpyrazol-3-yl)-1-(4-methoxyphenyl)cyclopropane-1-carboxamide
Show/Hide
|
C21H21N3O2
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0382578
|
(3R,5S)-N-benzyl-3,5-dimethyl-1-(pyridin-4-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 = 1710 nM
|
|
|
|
CP0518118
|
4-bromo-1,5-diphenyl-N-[(2-pyrazol-1-ylphenyl)methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H20BrN5O
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0452711
|
(3R,5S)-1-(benzenesulfonyl)-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C23H24N4O3S
|
1
|
| 1 |
IC50 = 1810 nM
|
|
|
|
CP0213567
|
4-[2-(ethylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C29H29F3N4O2
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0450867
|
(2R,4S)-3,3,9-trimethyl-N-[(4-methylphenyl)methyl]-8-thiatricyclo[4.3.0.02,4]nona-1(9),6-diene-7-carboxamide
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0534565
|
2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-3-(trifluoromethyl)-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H23F6N3O2
|
1
|
| 1 |
IC50 = 2030 nM
|
|
|
|
CP0475590
|
3-chloro-2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C21H24ClF3N2O2
|
1
|
| 1 |
IC50 = 2250 nM
|
|
|
|
CP0389208
|
2-[4-(dimethylamino)phenyl]-N-(1-phenylpyrazol-3-yl)acetamide
Show/Hide
|
C19H20N4O
|
1
|
| 1 |
IC50 = 2300 nM
|
|
|
|
CP0475591
|
3-chloro-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-4-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H23ClF3N3O2
|
1
|
| 1 |
IC50 = 2360 nM
|
|
|
|
CP0450850
|
3-bromo-N-[(2-ethoxyphenyl)methyl]-5,5-dimethyl-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C20H24BrNO2S
|
1
|
| 1 |
IC50 = 2760 nM
|
|
|
|
CP0408587
|
4-bromo-1-methyl-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C20H17BrF3N3O2
|
1
|
| 1 |
IC50 = 2850 nM
|
|
|
|
CP0450851
|
3-bromo-5,5-dimethyl-N-[(2-propan-2-yloxyphenyl)methyl]-6,7-dihydro-4H-2-benzothiophene-1-carboxamide
Show/Hide
|
C21H26BrNO2S
|
1
|
| 1 |
IC50 = 2930 nM
|
|
|
|
CP0412185
|
N-[1-[(4-acetamidophenyl)methyl]pyrazol-3-yl]-2-[4-(dimethylamino)phenyl]acetamide
Show/Hide
|
C22H25N5O2
|
1
|
| 1 |
IC50 = 3300 nM
|
|
|
|
CP0475697
|
(3R,5S)-1-benzyl-3,5-dimethyl-N-pyridin-3-yl-8-(2,2,2-trifluoroethoxy)-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27F3N4O2
|
1
|
| 1 |
IC50 = 3557 nM
|
|
|
|
CP0396363
|
4-[2-(diethylamino)ethyl]-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C31H33F3N4O2
|
1
|
| 1 |
IC50 = 4370 nM
|
|
|
|
CP0389181
|
3,5-dichloro-4-cyclopropyl-1-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]pyrrole-2-carboxamide
Show/Hide
|
C20H24Cl2N2O2
|
1
|
| 1 |
IC50 = 6530 nM
|
|
|
|
CP0471732
|
2,5,5-trimethyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
|
C20H24F3N3O2
|
1
|
| 1 |
IC50 = 7500 nM
|
|
|
|
CP0450863
|
4-(difluoromethyl)-1-(2-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H19F6N3O2
|
1
|
| 1 |
IC50 = 8600 nM
|
|
|
|
CP0429387
|
(2S,4R)-N-[(2-methoxyphenyl)methyl]-3,3,9-trimethyl-8,9-diazatricyclo[4.3.0.02,4]nona-1(6),7-diene-7-carboxamide
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 = 9000 nM
|
|
|
|
CP0382577
|
(3R,5S)-1-benzyl-3,5-dimethyl-4-(oxan-4-ylmethyl)-3,5-dihydro-2H-1,4-benzodiazepine
Show/Hide
|
C24H32N2O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0382619
|
(3R,5S)-1-benzoyl-N-benzyl-3,5-dimethyl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C26H27N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0424411
|
(4S,6R)-N,8-dibenzyl-1,4,6-trimethyl-6,7-dihydro-4H-pyrazolo[3,4-e][1,4]diazepine-5-carboxamide
Show/Hide
|
C24H29N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0444048
|
(3S,5R)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[3,4-e][1,4]diazepine-4-carboxamide
Show/Hide
|
C25H28N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0446026
|
(3R,5S)-1-benzyl-3,5-dimethyl-8-methylsulfonyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
|
C25H28N4O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389185
|
4-(difluoromethyl)-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H20F5N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0389187
|
1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H20F3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0396361
|
1-benzyl-4-(difluoromethyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C27H22F5N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0396362
|
4-bromo-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H19BrF3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0408586
|
4-bromo-1-(2-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H18BrF4N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0429394
|
1-benzyl-4-bromo-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C26H21BrF3N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0450861
|
4-bromo-1-(3-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
Show/Hide
|
C25H18BrF4N3O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0463423
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4-ethenyl-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
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C27H22F3N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0476828
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4-bromo-1,5-diphenyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]pyrazole-3-carboxamide
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C24H18BrF3N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0482011
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N-benzyl-1,5-diphenylpyrazole-3-carboxamide
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C23H19N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0482012
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4-(difluoromethyl)-1-(4-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
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C26H19F6N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0482015
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4-bromo-1,5-diphenyl-N-[[2-(2,2,2-trifluoroethoxy)pyridin-3-yl]methyl]pyrazole-3-carboxamide
Show/Hide
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C24H18BrF3N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0482016
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N-[(2-fluorophenyl)methyl]-1,5-diphenylpyrazole-3-carboxamide
Show/Hide
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C23H18FN3O
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1
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| 1 |
IC50 > 10000 nM
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CP0536149
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4-bromo-1-(4-fluorophenyl)-5-phenyl-N-[[2-(2,2,2-trifluoroethoxy)phenyl]methyl]pyrazole-3-carboxamide
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C25H18BrF4N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0429377
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3-chloro-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C20H23ClF3N3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0455786
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3-chloro-N-[[3-[(3S)-3-fluoropyrrolidin-1-yl]pyridin-2-yl]methyl]-2,5,5-trimethyl-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C22H28ClFN4O
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1
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| 1 |
IC50 > 10000 nM
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CP0471731
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3-chloro-2,5,5-trimethyl-N-[[2-(3,3,3-trifluoropropoxy)phenyl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C22H26ClF3N2O2
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1
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| 1 |
IC50 > 10000 nM
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CP0471733
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3-cyano-2,5,5-trimethyl-N-[[3-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl]-6,7-dihydro-4H-isoindole-1-carboxamide
Show/Hide
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C21H23F3N4O2
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1
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| 1 |
IC50 > 10000 nM
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CP0471734
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4-chloro-5-methyl-N-[[2-(2-methylpropoxy)phenyl]methyl]-2,3-dihydro-1H-pyrrolo[3,4-c]pyrrole-6-carboxamide
Show/Hide
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C19H24ClN3O2
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1
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| 1 |
IC50 > 10000 nM
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CP0412204
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N-(1-benzylpyrazol-3-yl)benzamide
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C17H15N3O
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1
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| 1 |
IC50 > 10000 nM
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CP0483095
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3-[1-[(3,4-difluorophenyl)methyl]pyrazol-3-yl]-5-(4-propan-2-ylphenyl)-1,2,4-oxadiazole
Show/Hide
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C21H18F2N4O
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1
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| 1 |
IC50 > 10000 nM
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CP0377010
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(3R,5S)-N-benzyl-3,5-dimethyl-1,2,3,5-tetrahydro-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C19H23N3O
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1
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| 1 |
IC50 > 8605 nM
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CP0382635
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(3R,5S)-N,1-dibenzyl-3,5-dimethyl-3,5-dihydro-2H-pyrido[4,3-e][1,4]diazepine-4-carboxamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 > 8740 nM
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CP0382621
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(3R,5S)-1-benzyl-9-methoxy-3,5-dimethyl-N-pyridin-3-yl-3,5-dihydro-2H-1,4-benzodiazepine-4-carboxamide
Show/Hide
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C25H28N4O2
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1
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| 1 |
IC50 > 9000 nM
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